The present invention relates to a large-screen mobile phone screen unlocking method and a large-screen mobile phone. The method comprises the steps: S1, screen unlocking interface display: a touch screen is started, a CPU module randomly generates a binary feature module and convert the binary feature module to a three-dimensional figure to display a three-dimensional figure random feature surface on the unlocking interface of the touch screen; S2, unlocking, the rotation of the three-dimensional figure in the horizontal direction and/or the vertical direction on the unlocking interface is controlled through the touch screen, when the three-dimensional figure rotates to a pre-unlocking feature surface, the confirmation input is performed through the touch screen, the CPU module is configured to compare whether the binary feature module of the three-dimensional figure pre-unlocking feature surface on the current unlocking interface is the same as a preset binary feature module or not, if the binary feature module of the three-dimensional figure pre-unlocking feature surface on the current unlocking interface is the same as a preset binary feature module, the CPU module controls the touch screen to unlock, and if the binary feature module of the three-dimensional figure pre-unlocking feature surface on the current unlocking interface is not the same as a preset binary feature module, the step returns back to the step 1 and the binary feature module of the three-dimensional figure feature surface is randomly reset. The large-screen mobile phone screen unlocking method and the large-screen mobile phone can rapidly unlock the mobile phone screen in the state that the mobile phone is stably held by one hand so as to overcome the convenient unlocking caused by the large screen of the mobile phone.