基本信息:
- 专利标题： 一种改善阿尔茨海默病认知功能障碍的组合物
- 专利标题（英）：Composition for improving Alzheimer's disease cognition impairment
- 申请号：CN201611194946.1 申请日：2016-12-20
- 公开(公告)号：CN106581307A 公开(公告)日：2017-04-26
- 发明人： 蒋与刚 , 庞伟 , 刘伟 , 杨亚丹 , 谭龙 , 杨红澎 , 孙寿丹
- 申请人： 中国人民解放军军事医学科学院卫生学环境医学研究所
- 申请人地址： 天津市和平区大理道1号
- 专利权人： 中国人民解放军军事医学科学院卫生学环境医学研究所
- 当前专利权人： 中国人民解放军军事医学科学院卫生学环境医学研究所
- 当前专利权人地址： 天津市和平区大理道1号
- 代理机构： 天津市北洋有限责任专利代理事务所
- 代理人： 陆艺
- 主分类号： A61K36/82
- IPC分类号： A61K36/82 ; A61P25/28 ; A61K31/714 ; A61K31/519 ; A61K31/4415 ; A61K31/375 ; A61K31/355 ; A61K33/30 ; A61K31/202
The invention discloses a composition for improving Alzheimer's disease cognition impairment. The composition comprises blueberry extract, Folium Ginkgo extract, vitamin B6, vitamin B12, vitamin E, vitamin C, folic acid, docosahexenoic acid, green tea polyphenol extract, zinc lactate and selenious yeast. A result of animal experiments shows that compared with AD model groups, the composition has the following advantages: obvious shortening of the latent time and obvious increase of the platform crossing frequency of experiment animal APP/PS1 mice in Morris water labyrinth experiments are realized, that is, the space learning memory ability is obviously improved; and the quantity of senile plaques in hippocampuses and cortical areas is obviously reduced, and the effect of the composition is better than individually supplemented blueberry extract. Above experiment result shows that a proper amount of the composition supplemented to an Alzheimer's disease model obviously improves the learning memory function disorder.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K36/00 | 含有来自藻类、苔藓、真菌或植物或其派生物，例如传统草药的未确定结构的药物制剂 |
| --------A61K36/18 | .被子植物亚门 |
| ----------A61K36/185 | ..双子叶植物纲 |
| ------------A61K36/82 | ...山茶科，如山茶 |