The invention relates to an organosilicon synthetic leather and a preparation method thereof. The organosilicon synthetic leather includes a top rubber layer, a bottom rubber layer and a base layer which are successively laminated, wherein the preparation materials of the top rubber layermainly include organic polysiloxane, organic hydrogenated polysiloxane, vinyl MTQ silicone resin and sphericalvinyl MQ silicone resin. And the above preparation materialsare mixed atan appropriate ratio to prepare the top rubber. The preparation materials of the bottom rubber layer mainly include organic polysiloxane, organic hydrogenated polysiloxane and vinyl MTQ silicone resin. And the above preparation materialsare mixed atan appropriate ratio to prepare the bottom rubber. The top rubber is coated onrelease papers. When the coated top rubber is cured, the bottom rubber is coated on the cured top rubber to form a bottom rubber layer. Then the bottom rubber layer is combined with the base layer. And the cured composite bottom layer is peeled off from the release papers, andtheorganosilicone synthetic leather is prepared. The organosilicone synthetic leather has excellent safety, abrasion resistance, anti-fouling resistance and flame retardancy. The preparation method of the organosilicone synthetic leather is simple and the preparation process does not require the use of solvents.