The invention discloses a high-toughness long-service-life rapid open-end wrench. A wrench body is provided with a clamping jaw capable of clamping a work piece; the clamping jaw is internally provided with an arc-shaped slide groove, an expansion groove and a slide block which can slide relative to the arc line of the slide groove; a first gripping jaw with a force applying plane is formed on theclamping jaw, and an evasion part is formed in the position, on the force applying plane, of the clamping jaw; when the clamping jaw rotates the work piece and generates elastic deformation, the expansion effect, within the elasticity limit, of the clamping jaw is improved through the expansion groove, thus, the end corner between a first forward stress surface and a sixth reverse stress surfaceof the work piece can cross the force applying plane of the first gripping jaw to enter the evasion part, the situation that the slide block and the first gripping jaw cannot bear the reacting force coming from the work piece and are damaged is avoided, and the rapid open-end wrench has the high toughness and the long service life.