The invention discloses a regeneration device and clothes treatment equipment. The regeneration device comprises a regeneration shell and at least one partition plate, wherein a cavity used for containing saline water is defined in the regeneration shell; at least one part of the partition plates are non-horizontally arranged in the regeneration shell so as to divide the cavity, and a plurality ofscreen holes which are communicated in the thickness direction are formed in the partition plates. According to the regeneration device in the embodiment, by arranging at least one part of non-horizontal partition plates in the cavity and forming the screen holes in the partition plates, the water flow speed is reduced, regenerated salt particles or regenerated salt blocks are quickly and fully dissolved in the cavity, the situation that the salt particles or the salt blocks block the regeneration device, and accordingly, use is affected can be avoided, and moreover, the concentration of thesaline water meets requirements.