The invention belongs to the technical field of medical instruments, and particularly relates to a rotary loading syringe and injector system with a pressure sleeve. The system is characterized by comprising a syringe, a push rod, a syringe body and a piston; the syringe body is composed of a far end, a near end and a central section between the far end and the near end, wherein the far end is composed of an injection neck and a conical surface, the central section is a whole section of a cylinder with the same outer diameter and inner diameter, and the near end is a cylinder with the inner diameter slightly larger than that of the central section. The part, with protrusions, of the far end can follow an injector bracket rotating body to rotate, the piston is composed of a conical surface,a sealing ring, a step for clamping the sealing ring and a boss with the step, the sealing ring is matched with the step for clamping the sealing ring, a push rod is locked with the boss through thestep, and therefore the piston is driven to move front and back. The novel rotary-free loading syringe and injector system with the pressure sleeve is suitable for computed tomography scanning equipment (CT), nuclear magnetic resonance equipment (MRI), digital subtraction angiography equipment (DSA) and the like, the experience of users is improved, and the installation time for the users is saved.