The invention discloses a nutrient substitute food for tumor recovery and a preparation method of the nutrient substitute food. The nutrient substitute food is prepared from the following raw materials in parts by weight: 1-2 parts of superoxide dismutase dry powder, 1-2 parts of ganoderma lucidum spore powder, 5-8 parts of Tuckahoe, 20-35 parts of oat, 4-6 parts of sesame, 5-7 parts of walnut kernels, 0.5-2 parts of radix semiaquilegiae, 3-6 parts of peach kernels, 1-3 parts of tremella fuciformis, 0.2-1 part of cream powder and 15-20 parts of soybeans. The various raw materials are compatible and synergistic, so that the nutrient substitute food has the functions of strengthening the body resistance to eliminate pathogenic factors, promoting blood circulation to remove blood stasis, clearing away heat and toxic materials, harmonizing liver-spleen, suppressing tumor growth and enhancing the immunity, improves the tolerance of tumor patients to operations, radiotherapy and chemotherapy, is also capable of meeting the nutrient demands of the tumor patients, relieving accompanying symptoms of patients suffering from malignant tumor radiotherapy and chemotherapy if being eaten for a long term and achieving the aims of strengthening the body resistance to eliminate pathogenic factors, relieving the symptoms, enhancing the immunity of the patients and prolonging the lifetime, is a food suitable for patients accepting operations, radiotherapy and chemotherapy in a recovery period and is beneficial to the physical recovery of the tumor patients.