The utility model is a deaeration device provided with electrical and mechanical dual interlock structure comprising a pressure chamber body, a hinged face plate being arranged on a front end of the pressure chamber body, a tooth-type flange being installed on a door and the chamber, having a rotary hoop installed on the external part, a pressure-type positioning pin being installed on the upper part of the door, a pressure-type V-shaped sealing strip being installed in the middle of the tooth-type flange. The utility model is equipped with set of flange interlock structure, the pressure linkage positioning pin, and the mechanical and electrical dual interlock device, therefore it ensures that the operating staff cannot open the door with pressure; the sealed part is provided with pressure V-type sealing ring, which will be sealed along with fluctuation of the pressure, so that it is safe and convenient.