The utility model relates to a 2.1 multimedia integrated sound box. The sound box comprises a wooden box (14), a woofer (13) on the front surface of the wooden box, a guide pipe (19) on the back surface of the wooden box and a control circuit board electrically connected with the woofer, and is characterized by further comprising a left channel horn (151) and a right channel horn (152) which are electrically connected with the control circuit board and are fixedly mounted on the left side and the right side of the wooden box respectively, and the left channel horn and the right channel horn are completely isolated from a bass cavity formed by the enclosed space in the wooden box through a flexible sealing layer (17) which covers the outer surface of the respective basin stand and seals theair guide through hole and the respective shells. The loudspeaker box is lower in cost, simple in process, larger in bass resonance space, higher in mid-high pitch sound pressure and better in tone quality while concentrating space.