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    • 68. 发明授权
    • 표면적 및/또는 다공성이 조절된 당알콜을 담체로 이용한 리포솜 조성물 및 그의 제조방법
    • 使用表面区域和改性糖醇作为载体的制剂制剂及其制备方法
    • KR101598752B1
    • 2016-02-29
    • KR1020150013399
    • 2015-01-28
    • 순천향대학교 산학협력단
    • 송건형
    • A61K9/127A61K47/36A61K47/30
    • A61K47/26A61K8/345A61K8/60A61K9/127A61K9/1271A61K47/30A61K47/36G01N25/4866
    • 본발명은고체상의유동성이있으면서표면적및/또는다공성이증가되거나감소된즉 조절된신규한당알콜의제조방법, 이제조방법에의해제조된당알콜, 또는이 당알콜을담체로서포함하는약제학적조성물, 화장료조성물, 식품조성물, 사료조성물에관한것이다. 본발명의당알콜의제조방법은 (A) 고체상태의당알콜이용매(S)에의해용해되지않고고체분산체로서용매(S)와반응되는단계및 (B) 상기용매(S)를제거하는단계를포함한다. 본발명의제조방법으로제조된당알콜은기존의당알콜에비하여표면적및/또는다공성이증가또는감소, 즉조절된다. 이러한제조방법에의해제조된당알콜을담체또는피코팅체등 그자체로서활용하거나, 또는이를의약품, 식품, 화장품, 사료등의조성물의구성요소로사용시, 담체에대한유효성분의비율을조절할수 있어제형/제조또는조성물의제조에활용할수 있다.
    • 本发明涉及一种制备表面积和/或孔隙率增加或降低的糖醇的新方法,即具有固相流动性的调节,通过相同制备方法制备的糖醇和药物组合物,化妆品 组合物,食物组合物和含有糖醇作为载体的饲料组合物。 制备本发明的糖醇的方法包括以下步骤:(A)使固体糖醇与溶剂(S)作为固体分散体反应而不被溶剂(S)溶解; 和(B)除去溶剂(S)。 通过本发明的制备方法制备的糖醇的表面积和/或孔隙率增加或降低,即与常规的糖醇相比调节。 通过制备方法制备的糖醇,当作为载体和被涂物的本身被使用或用作组合物的组分如药物,食品,化妆品和饲料等时。 可以调节活性成分与用于配制/制备或制备组合物的载体的比例。
    • 69. 发明授权
    • 복렬구조 열유속 측정게이지
    • 用于测量具有双向线的热通量的量具
    • KR101221972B1
    • 2013-01-15
    • KR1020120073336
    • 2012-07-05
    • 한국기계연구원
    • 이정호오동욱이공훈
    • G01K17/08G01K17/00B21B37/74
    • G01K17/20B21B37/74G01N25/4866
    • PURPOSE: A heat flux measurement gauge of a double-row structure is provided to measure temperature at two points which are spaced from each other along a thickness direction of a rear plate near a surface of the rear plate and to measure heat flux and heat transfer coefficient on the surface of the rear plate in which errors caused by cooling fluid are eliminated by arranging a case on the surface of the rear plate to prevent the cooling fluid being in contact with a lateral side of the rear plate. CONSTITUTION: A heat flux measurement gauge of a double-row structure comprises an upper plate(110), a body(120), a heater(160), a first temperature sensor unit, a second temperature sensor unit, and a case(150). The upper plate is in contact with sprayed cooling fluid. The body is joined to the upper part so that an edge of the body forms a stepped portion by being extended to an edge of the upper plate to an outer side. The heater is installed in the body, thereby heating the upper plate and the body. The first temperature sensor unit is arranged in one end portion of the upper plate and measures the temperature of a first measurement unit. The second temperature sensor unit is arranged in the other end portion of the upper plate to be corresponded to the first temperature sensor unit and measures the temperature of a second measurement unit. A through-groove is formed in the central portion of the case so that the case is joined to the stepped portion formed by the upper plate and body. The case is formed so that fluid cooling the upper plate by being sprayed on the upper plate is spaced from an exterior surface of the upper plate.
    • 目的:提供双排结构的热通量测量计,以测量两个点之间的温度,这两个点沿后板附近的后板的厚度方向彼此间隔开,并测量热通量和热传递 通过在后板的表面上布置壳体以防止冷却流体与后板的侧面接触,消除了由冷却液引起的错误导致的后板的表面上的系数。 构造:双列结构的热通量测量计包括上板(110),主体(120),加热器(160),第一温度传感器单元,第二温度传感器单元和壳体(150 )。 上板与喷射冷却液接触。 主体接合到上部,使得主体的边缘通过向上延伸到上板的边缘而形成台阶部分。 加热器安装在主体中,从而加热上板和主体。 第一温度传感器单元布置在上板的一个端部中并测量第一测量单元的温度。 第二温度传感器单元布置在上板的另一端部,以对应于第一温度传感器单元,并测量第二测量单元的温度。 在壳体的中央部形成有贯通槽,使得壳体与由上板和主体形成的阶梯部接合。 壳体形成为使得通过喷射在上板上冷却上板的流体与上板的外表面间隔开。