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81. 发明授权

US08086351B2 Methods and systems for area search using a plurality of unmanned vehicles 有权
标题翻译：使用多个无人驾驶车辆进行区域搜索的方法和系统
公开(公告)号：US08086351B2
公开(公告)日：2011-12-27
申请号：US11052386
申请日：2005-02-07
申请人： Paolo Gaudiano , Benjamin Shargel , Eric Bonabeau
发明人： Paolo Gaudiano , Benjamin Shargel , Eric Bonabeau
IPC分类号： G05B19/04 , G05B19/18
CPC分类号： G01C11/00 , G05D1/104
摘要： Disclosed are methods and systems that include a method for controlling movement of a first unmanned vehicle (UV) to search an area, where the method includes generating a first trace associated with prior positions in which the first UV has been located, determining a direction in which the first UV is to move using the first generated trace, and causing the first UV to move in the determined direction. The trace may be a numerical value that decreases as a function of the time that has elapsed since the first trace was generated. The methods and systems may also include receiving data relating to a second trace, and using that second trace to determine the direction. The second trace may be generated by a second UV. The second trace may be associated with a position within a predetermined radius from a position associated with the first UV.
摘要翻译：公开了包括用于控制第一无人驾驶车辆（UV）的移动以搜索区域的方法和系统，其中该方法包括生成与其中已经位于第一UV的先前位置相关联的第一轨迹，确定方向第一UV将使用第一生成的迹线移动，并且使得第一UV沿所确定的方向移动。跟踪可以是随着从生成第一个跟踪以来经过的时间的函数而减小的数值。方法和系统还可以包括接收与第二跟踪有关的数据，并且使用该第二跟踪来确定方向。第二个痕迹可以由第二个UV产生。第二迹线可以与从与第一UV相关联的位置的预定半径内的位置相关联。

82. 发明授权

US08001922B2 Application of a coating on a medical device 有权
标题翻译：涂在医疗器械上的应用
公开(公告)号：US08001922B2
公开(公告)日：2011-08-23
申请号：US11238554
申请日：2005-09-28
申请人： Roger Labrecque , Geoffrey Moodie , Joseph Ferraro , Lisa Rogers , Paul Martakos , Theodore Karwoski , Steve A. Herweck , Suzanne Conroy , Brian Sunter , Georgette Henrich
发明人： Roger Labrecque , Geoffrey Moodie , Joseph Ferraro , Lisa Rogers , Paul Martakos , Theodore Karwoski , Steve A. Herweck , Suzanne Conroy , Brian Sunter , Georgette Henrich
IPC分类号： B05C1/00
CPC分类号： A61L31/08 , A61F2/82 , A61F2/86 , A61F2250/0067 , A61K47/10 , A61K47/22 , A61K47/44 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/22 , A61L2300/416 , A61L2300/428 , A61L2300/45 , A61L2300/606 , A61L2300/802 , A61L2420/02 , A61M25/0009 , A61M25/0045
摘要： Devices for the provision of a coating on an implantable medical device are provided. The coating includes a bio-absorbable carrier component. In addition to the bio-absorbable carrier component, a therapeutic agent component can also be provided. The devices provide a coating having improved uniformity and coverage which in turn allow for greater control of the amount and dosage of the coating.
摘要翻译：提供了用于在可植入医疗装置上提供涂层的装置。涂层包括生物吸收载体组分。除了生物可吸收载体组分之外，还可以提供治疗剂成分。这些装置提供具有改进的均匀性和覆盖度的涂层，这又允许更大程度地控制涂层的量和剂量。

83. 发明授权

US11636418B2 Currency reduction for predictive human resources synchronization rectification 有权
公开(公告)号：US11636418B2
公开(公告)日：2023-04-25
申请号：US16902944
申请日：2020-06-16
申请人： PredictiveHR, Inc.
发明人： William M. Lyerly , Charles Occhino
IPC分类号： G06Q10/00 , G06Q10/0637 , G06Q10/1053 , G06F16/23 , G06F16/25 , G06N20/00 , G06Q40/12 , G06Q30/0204 , G06Q20/38 , G06N5/04 , G06F18/00
摘要： A method and system for repairing data with incongruent or incompatible types that detects anomalies in human resources data, and if anomalies are present in the data, then suggests to a user corrections and synchronizing actions that better match patterns in the data, specifically listing reasons why the data is potentially erroneous and justifies the suggestion based on objective data to aid the user in accepting corrections and synchronizing actions or performing further review and analysis on the data using the method and system.

84. 外观设计

USD978768S1 Aircraft airframe 有权
公开(公告)号：USD978768S1
公开(公告)日：2023-02-21
申请号：US29779140
申请日：2021-05-13
申请人： Alakai Technologies Corporation
设计人： Brian D. Morrison , Andre H. De Salis , Martti J. Lampela , Adil M. Ali , Peter F. Falt

85. 发明授权

US11573545B2 Interactive dynamic interface for capacitor control 有权
公开(公告)号：US11573545B2
公开(公告)日：2023-02-07
申请号：US16777518
申请日：2020-01-30
申请人： Advanced Control Systems Corporation
发明人： Charles W. Marshall, Jr. , Peter Battelino , Spartak Daci , David Rossano-Collier
IPC分类号： G05B19/042 , G06F3/0488 , G06F3/048 , H02J3/06 , H02J50/00
摘要： A system, method and apparatus for an interactive dynamic interface for wireless distributed capacitor control that comprises a touchscreen display that eliminates the conventional dials and switches that are part of a conventional control, and with these efficiencies can locally, remotely or autonomously implement “personality” settings for the capacitor control that speeds and simplifies custom configurations and recovery in relation to user, electrical and environmental input that meets certain operating criteria, including after a shut-down event, thereby improving the of the capacitor control system to function more appropriately, effectively, and efficiently under a greater range of parameters.

86. 发明授权

US11512291B2 Satellite cells and compositions and methods for producing the same 有权
公开(公告)号：US11512291B2
公开(公告)日：2022-11-29
申请号：US16297548
申请日：2019-03-08
申请人： President and Fellows of Harvard College
发明人： Lee L. Rubin , Feodor D. Price
IPC分类号： C12N5/077 , A61K35/34 , A61K35/12
摘要： Disclosed herein are methods for generating satellite cells and compositions including satellite cells.

87. 发明授权

US11499981B2 Methods of identifying modulators of SAMTOR-GATOR1 interaction and use of same to modulate mTORC1 有权
公开(公告)号：US11499981B2
公开(公告)日：2022-11-15
申请号：US16164644
申请日：2018-10-18
申请人： Whitehead Institute for Biomedical Research
发明人： David M. Sabatini , Xin Gu , Jose M. Orozco
IPC分类号： G01N33/53 , G01N33/68 , A61K38/00 , G01N33/48 , C12Q1/00 , G01N33/50 , C07K19/00 , G01N33/532
摘要： The invention relates to methods of identifying compounds that modulate mTORC1 activity in a cell by modulating the activity of SAMTOR, as well as to the use of such identified compounds in the modulation of mTORC1 and the treatment of diseases and conditions characterized by aberrant mTORC1 activity.

88. 发明授权

US11434476B2 Methods of editing DNA methylation 有权
公开(公告)号：US11434476B2
公开(公告)日：2022-09-06
申请号：US16326700
申请日：2017-08-18
申请人： Whitehead Institute for Biomedical Research
发明人： Rudolf Jaenisch , X Shawn Liu , Hao Wu
IPC分类号： C12N9/22 , A61K35/30 , A61K35/33 , C12N9/10 , C12N15/11 , C12N15/86 , C12N15/90 , A61P3/10 , A61P9/00 , A61P9/10 , A61P9/12 , A61P11/00 , A61P25/00 , A61P25/16 , A61P25/28 , A61P35/00 , A61P37/06 , A61K38/46 , C12N15/00 , C12N15/113 , A61K31/7088
摘要： The invention relates to methods of modifying DNA methylation by contacting a catalytically inactive site specific nuclease fused to an effector domain having methylation or demethylation activity and one or more guide sequences.

89. 发明授权

US11419901B2 Porphyromonas gingivalis immune modulators and uses thereof 有权
公开(公告)号：US11419901B2
公开(公告)日：2022-08-23
申请号：US16964577
申请日：2019-01-23
申请人： Trustees of Tufts College
发明人： Caroline Attaro Genco , George Papadopoulos
IPC分类号： A61K35/74 , A61P37/02 , A61P35/00 , A61K39/00 , A61K39/39
摘要： A heat killed Porphyromonas gingivalis bacterium expressing a homogenous lipid A structure having a molecular negative mass ion of 1368, 1435/1449, or 1690/1768 is used as an immunomodulator. The immunomodulator may be used in combination with an antigen of interest to potentiate or restrain a host immune response toward the selected antigen.

90. 发明授权

US11407828B2 Anti-CLauDiN 18 antibodies and methods of use thereof 有权
公开(公告)号：US11407828B2
公开(公告)日：2022-08-09
申请号：US17427909
申请日：2020-02-03
申请人： NovaRock Biotherapeutics, Ltd.
发明人： Han Li , Ming Lei , Yi Pei , Haichun Huang
IPC分类号： C07K16/28
摘要： Antibodies that specifically bind to the human tight junction molecule CLDN18.2 and have functional properties that make them suitable for use in antibody-based immunotherapies of a disease associated with aberrant expression of CLDN18.2 are disclosed.

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