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1. 发明申请

WO2013055940A3 NON-REGULAR ELECTRICAL STIMULATION PATTERNS FOR TREATING NEUROLOGICAL DISORDERS 审中-公开
标题翻译：用于治疗神经疾病的非正常电刺激模式
公开(公告)号：WO2013055940A3
公开(公告)日：2014-05-30
申请号：PCT/US2012059787
申请日：2012-10-11
申请人： UNIV DUKE , GRILL WARREN M , BROCKER DAVID T , BIRDNO MERRILL J
发明人： GRILL WARREN M , BROCKER DAVID T , BIRDNO MERRILL J
IPC分类号： A61N1/00
CPC分类号： A61N1/36067 , A61N1/0534 , A61N1/36082 , A61N1/36178 , A61N1/36196
摘要： Systems and methods for stimulation of neurological tissue and generation stimulation trains with temporal patterns of stimulation, in which the interval between electrical pulses (the inter-pulse intervals) changes or varies over time. The features of the stimulation trains may be selected and arranged algorithmically to by clinical trial. These stimulation trains are generated to target a specific neurological disorder, by arranging sets of features which reduce symptoms of that neurological disorder into a pattern which is effective at reducing those symptoms while maintaining or reducing power consumption versus regular stimulation signals. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention provide increased efficacy and/or a lower than average frequency.
摘要翻译：用于刺激神经组织和生成刺激训练的系统和方法，其中刺激的时间模式（电脉冲间隔（脉冲间隔）随时间变化）变化。可以通过临床试验来选择和布置刺激训练的特征。产生这些刺激训练是为了靶向特定的神经系统疾病，通过将能够将神经系统疾病的症状减少到有助于减少这些症状同时维持或降低功率消耗与常规刺激信号的模式的一组特征。与具有规则（即，恒定）脉冲间隔的常规连续高速脉冲串相比，体现本发明特征的非规则（即不是恒定的）脉冲模式或火车提供增加的功效和/或低于平均频率

2. 发明申请

WO2013055940A2 NON-REGULAR ELECTRICAL STIMULATION PATTERNS FOR TREATING NEUROLOGICAL DISORDERS 审中-公开
标题翻译：用于治疗神经疾病的非正常电刺激模式
公开(公告)号：WO2013055940A2
公开(公告)日：2013-04-18
申请号：PCT/US2012/059787
申请日：2012-10-11
申请人： DUKE UNIVERSITY , GRILL, Warren, M. , BROCKER, David, T. , BIRDNO, Merrill, J.
发明人： GRILL, Warren, M. , BROCKER, David, T. , BIRDNO, Merrill, J.
IPC分类号： A61N1/32
CPC分类号： A61N1/36067 , A61N1/0534 , A61N1/36082 , A61N1/36178 , A61N1/36196
摘要： Systems and methods for stimulation of neurological tissue and generation stimulation trains with temporal patterns of stimulation, in which the interval between electrical pulses (the inter-pulse intervals) changes or varies over time. The features of the stimulation trains may be selected and arranged algorithmically to by clinical trial. These stimulation trains are generated to target a specific neurological disorder, by arranging sets of features which reduce symptoms of that neurological disorder into a pattern which is effective at reducing those symptoms while maintaining or reducing power consumption versus regular stimulation signals. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention provide increased efficacy and/or a lower than average frequency.
摘要翻译：用于刺激神经组织和生成刺激训练的系统和方法，其中刺激的时间模式（电脉冲间隔（脉冲间隔）随时间变化）变化。可以通过临床试验来选择和布置刺激训练的特征。产生这些刺激训练是为了靶向特定的神经系统疾病，通过将能够将神经系统疾病的症状减少到有助于减少这些症状同时维持或降低功率消耗与常规刺激信号的模式的一组特征。与具有规则（即，恒定）脉冲间隔的常规连续高速脉冲串相比，体现本发明特征的非规则（即不是恒定的）脉冲模式或火车提供增加的功效和/或低于平均频率

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