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1. 发明专利

JP2010046080A Expression cloning in filamentous fungus 审中-公开
标题翻译：在真菌中表达克隆
公开(公告)号：JP2010046080A
公开(公告)日：2010-03-04
申请号：JP2009241780
申请日：2009-10-20
申请人： Koninkl Dsm Nv , コニンクリーケデーエスエムナムローゼフェンノートシャップ
发明人： VAN DEN BRINK JOHANNES MAARTEN , SELTEN GERARD CORNELIS MARIA , VAN DEN HOMBERGH JOHANNES PETRUS THEODORUS WILHELM
IPC分类号： C12N15/09 , C12N1/15 , C12N9/16 , C12N9/24 , C12N15/10 , C12N15/80 , C12P21/02 , C12Q1/68 , C12R1/66 , C12R1/685
CPC分类号： C12N15/1086 , C12N15/1034 , C12N15/80
摘要： PROBLEM TO BE SOLVED: To provide a method for isolating a DNA sequence encoding protein(s) having properties of interest by means of expression cloning in filamentous fungal host cells.
SOLUTION: The method comprises (a) a step of preparing a DNA library as an appropriate cloning vector from an organism supposed to have the ability to produce one or more proteins having properties of interest, (b) a step of transforming filamentous host cells by the DNA library, (c) a step of culturing transformed cells obtained in the step (c) under the condition of inducing the expression of the DNA sequence of the DNA library, and (d) a step of screening the transformed cell clone expressing the protein (s) having properties of interest by analysis of the protein (s) produced in the step (c).
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：待解决的问题：提供通过在丝状真菌宿主细胞中的表达克隆分离编码具有感兴趣性质的蛋白质的DNA序列的方法。解决方案：该方法包括（a）从被认为具有产生一种或多种具有感兴趣性质的蛋白质的能力的生物体制备作为合适的克隆载体的DNA文库的步骤，（b）转化丝状的步骤宿主细胞，（c）在诱导DNA文库的DNA序列表达的条件下培养在步骤（c）中获得的转化细胞的步骤，和（d）筛选转化细胞的步骤通过分析步骤（c）中产生的蛋白质来表达具有感兴趣性质的蛋白质的克隆。版权所有（C）2010，JPO＆INPIT

2. 发明专利

JP2006036989A Liquid state, curable resin composition 有权
标题翻译：液体状态，可固化树脂组合物
公开(公告)号：JP2006036989A
公开(公告)日：2006-02-09
申请号：JP2004221113
申请日：2004-07-29
申请人： Jsr Corp , Jsr株式会社 , Koninkl Dsm Nv , コニンクラッケデーエスエムエヌヴィKoninnklijke DSM N.V.
发明人： YAMAGUCHI CHIYUUSHI , KAMO OSAMU , SHIGEMOTO TAKEO
IPC分类号： C08F299/06
摘要： PROBLEM TO BE SOLVED: To provide a liquid state curable resin composition having conventional characteristics as a protecting film of a secondary material or tape material and also showing a good surface property having a low adhering force between the cured materials.
SOLUTION: This liquid state curable resin composition contains the following components (A) and (B). (A) A urethane (meth)acrylate as a reaction product of a polyether polyol, a polyisocyanate and a hydroxy group-containing (meth)acrylate and having ≥800 and
摘要翻译：要解决的问题：提供具有常规特性的液态固化树脂组合物作为二次材料或带材的保护膜，并且还显示出在固化材料之间具有低粘附力的良好的表面性质。该液状固化型树脂组合物含有下列成分（A）和（B）。（A）作为聚醚多元醇，多异氰酸酯和含羟基（甲基）丙烯酸酯的反应产物的氨基甲酸酯（甲基）丙烯酸酯，其数均分子量≥800和<4000。（B）作为与异氰酸酯基反应的聚醚多元醇，多异氰酸酯和乙烯基化合物的反应产物，具有≥4,000和≤2,000数均分子量的聚氨酯乙烯基醚。版权所有（C）2006，JPO＆NCIPI

3. 发明专利

JP2005097110A Coating material system for glass adhesivity retention 有权
标题翻译：玻璃胶粘剂涂料系统
公开(公告)号：JP2005097110A
公开(公告)日：2005-04-14
申请号：JP2004289464
申请日：2004-10-01
申请人： Dsm Nv , デーエスエムエヌ.ヴェー.
发明人： SZUM DAVID M
IPC分类号： G02B6/44 , C03C17/32 , C03C25/10 , C03C25/24 , C03C25/26 , C08F2/46 , C08G18/67 , C21D9/60 , C23C2/28
CPC分类号： C03C25/26 , C03C17/32 , C03C25/106 , C03C25/1065 , C08G18/672 , C21D9/60 , C23C2/28 , Y02P10/253 , Y10T428/2938 , Y10T428/2942 , Y10T428/2947 , C08G18/62
摘要： PROBLEM TO BE SOLVED: To obtain an improved coating material composition for glass substrates that comprises a tetrasubstituted compound. SOLUTION: The introduction of the tetrasubstituted compound into a coating material composition for the glass substrates, and in particular, for an optical fiber, acts to delay the rate of deterioration of the glass or optical fiber due to moisture, and improves adhesivity between the glass substrate and the coating material composition. The introduction of the tetrasubstituted compound into a polymeric coating material composition also improves the interlayer adhesivity when more than one coating materials are applied to a glass substrate. An outer primary coating material composition or a matrix material that comprises an acid functional ethylenically unsaturated monomer is further provided. An improved coated glass substrate having a decreased rate of deterioration due to moisture, improved adhesivity between the glass substrate and the coating material composition and between coatings of various coating materials, wherein the coating material composition comprises the tetrasubstituted compound, is also provided. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：获得包含四取代化合物的玻璃基板的改进的涂料组合物。解决方案：将四取代化合物引入用于玻璃基板，特别是光纤的涂料组合物中，用于延迟由于水分导致的玻璃或光纤的劣化速率，并提高粘合性在玻璃基板和涂层材料组成之间。将四取代化合物引入聚合物涂料组合物中，当将多于一种涂料施用于玻璃基底时，还可提高层间粘合性。进一步提供包含酸官能烯键式不饱和单体的外部初级涂料组合物或基质材料。还提供了一种改进的涂覆玻璃基板，其具有由于水分降低的劣化速率，改善了玻璃基板和涂层材料组成之间的粘合性以及各种涂层材料的涂层之间，其中涂层材料组合物包含四取代化合物。版权所有（C）2005，JPO＆NCIPI

4. 发明专利

JP2003065467A Pressurized fluid conduit 有权
标题翻译：加压流体管道
公开(公告)号：JP2003065467A
公开(公告)日：2003-03-05
申请号：JP2002174577
申请日：2002-06-14
申请人： Dsm Nv , ディーエスエムエヌ.ブイ.
发明人： KOENEN JACOB
IPC分类号： F16L11/06 , B29C49/04 , B29K67/00 , B29L23/00 , B29L31/30 , B32B1/08 , F16L9/12 , F16L11/00 , F16L11/04 , F16L11/11
CPC分类号： B32B1/08 , F16L9/12 , F16L11/04 , Y10S138/07 , Y10T428/1397
摘要： PROBLEM TO BE SOLVED: To inexpensively manufacture a pressurized fluid conduit superior in flexibility or bending flexibility by a comparatively simple method. SOLUTION: The pressurized fluid conduit includes a monolayer of a semicrystalline thermoplastic substance having hardness of 50-65 Shore D and an elastic modulus of at least 60 MPa at 150 deg.C. The conduit is formed by extrusion blow molding. An advantage of the conduit is simple manufacture, for example, easy handling and assembly at room temperature while necessary conditions are still satisfied regarding a burst pressure and deformation at raised operating temperature. Other important advantages include a significant reduction in substance usage and favorable damping of vibration and noise.
摘要翻译：要解决的问题：通过比较简单的方法廉价地制造柔性或弯曲柔软性优异的加压流体导管。解决方案：加压流体导管包括硬度为50-65肖氏D的半结晶热塑性物质的单层，在150℃下的弹性模量为至少60MPa。导管通过挤出吹塑成型形成。导管的优点是简单的制造，例如，在室温下易于处理和组装，同时在升高的工作温度下对爆裂压力和变形仍然满足必要条件。其他重要优点包括物质使用的显着减少和振动和噪音的有利的阻尼。

5. 发明专利

JP2002097235A LIQUID CURABLE RESIN COMPOSITION AND ITS CURED PRODUCT 失效
公开(公告)号：JP2002097235A
公开(公告)日：2002-04-02
申请号：JP2000291391
申请日：2000-09-26
申请人： JSR CORP , DSM NV
发明人： SUGIMOTO MASANOBU , HASHIGUCHI ETSUJI , KOMIYA ZEN , UKAJI TAKASHI
IPC分类号： G02B6/44 , C08F2/44 , C08F2/46 , C08F290/06 , C08G18/48 , C08G18/67 , C09D175/16
摘要： PROBLEM TO BE SOLVED: To provide a liquid curable resin composition composed of a transparent material and whose surface of a cured product is smooth, and which gives a cured product with which resin does not stick each other. SOLUTION: (A) A urethane (meth)acrylate obtained by reaction of a diol shown by the formula (I), a diisocyanate, and a (meth)acrylate having a hydroxyl group. (In the formula, R1 shows a hydrogen atom or a methyl group independently with each other, R2 shows a hydrogen atom, a methyl group, or a propyl group, m or n is the number of 5-95 respectively; however the total of m and n is 20-100), (B) A non-polymerizable polysiloxane whose number average molecular weight is 200-100,000, and (C) a liquid curable resin composition including a polymerizable monomer capable of copolymerizing the urethane (meth)acrylate (A) are provided.

6. 发明专利

JP2002088039A PROCESS FOR PREPARING (SCHIFF BASE OF) alpha-ALKYL-alpha-AMINO ACID AMIDE 审中-公开
公开(公告)号：JP2002088039A
公开(公告)日：2002-03-27
申请号：JP2001212314
申请日：2001-07-12
申请人： DSM NV
发明人： CALLANT DOMINIQUE MONIQUE CHAR , MINK DANIEL , CASTELIJNS ANNA MARIA CORNELIA
IPC分类号： C07C231/06 , C07C237/06 , C07C237/20 , C07C249/02 , C07C251/04 , C07C251/16 , C07C251/24
摘要： PROBLEM TO BE SOLVED: To provide a process by which a Schiff base of an α-alkyl-α-amino acid amide and an aldehyde can be prepared with a high yield and a high selectivity even when a reaction mixture contains water. SOLUTION: This process comprises bringing the corresponding α-aminonitrile into contact with a base and the aldehyde and ensuring that the reagents are in good contact. The resultant Schiff base may further be hydrolyzed to form the α-alkyl-α-amino acid amide and the aldehyde. A substituted or an unsubstituted benzaldehyde is preferably used as the aldehyde. The reaction is preferably carried out in a practically homogeneously mixed phase obtained by using a solvent, e.g. methanol or ethanol. NaOH or KOH is preferably used as the base.

7. 发明专利

JP2002037767A METHOD FOR RACEMIZING SCHIFF BASE OF AMINO ACID AMIDE HAVING HIGH ENANTIOMER CONTENT 审中-公开
公开(公告)号：JP2002037767A
公开(公告)日：2002-02-06
申请号：JP2001190159
申请日：2001-06-22
申请人： DSM NV
发明人： HOF ROBERT PATRICK , HERMSEN PETRUS JOHANNES , DE BODE RONUS
IPC分类号： C07B55/00 , C07C249/02 , C07C251/24
摘要： PROBLEM TO BE SOLVED: To provide a method for racemizing a Schiff base of a primary amino acid amide without causing the problem of no or slow progress of the reaction in conventional method using a base derived from an alkali or alkaline earth metal hydroxide and a tetraalkylammonium hydroxide and a water-miscible organic solvent. SOLUTION: The objective method for the racemization of a Schiff base of a primary amino acid amide having high enantiomer content uses a strong base chemically reactive with water. The reaction is carried out in an organic solvent using a metal alkoxide, an alkyl metal, a metal amide or a metal hydride, especially a metal alkoxide as the strong base. The Schiff base is preferably N-benzylidene primary amino acid amide and the primary amino acid amide is preferably derived from an aliphatic primary amino acid amide, e.g. t-leucinamide. The organic solvent is aromatic hydrocarbon, alicyclic hydrocarbon or ether, especially aromatic hydrocarbon.

8. 发明专利

JP2001348412A LIQUID CURABLE RESIN COMPOSITION AND BILAYER FILM 失效
公开(公告)号：JP2001348412A
公开(公告)日：2001-12-18
申请号：JP2001034191
申请日：2001-02-09
申请人： JSR CORP , DSM NV
发明人： KOMIYA ZEN , UKAJI TAKASHI
IPC分类号： G02B6/44 , B32B27/40 , C08F2/44 , C08F2/48 , C08F290/06 , C08J7/04
摘要： PROBLEM TO BE SOLVED: To provide a liquid curable resin composition capable of giving a tape material which has such characteristics as to be completely separated from a colored layer in separating an optical fiber tape core wire. SOLUTION: This resin composition contains (1) 30-80 wt.% urethane (meth) acrylate prepared by reacting (A) a polyol compound, (B) a polyisocyanate compound, and (C) a hydroxyl-group-containing (meth)acrylate compound, (2) 0.01-10 wt.% 2-methyl-1-[4-(methylthio)phenyl]-2-morpholinopropan-1-one, and (3) 10-70 wt.% polymerizable diluent containing a monofunctional vinyl monomer copolymerizable with component (1).

9. 发明专利

JP2001316434A CURABLE LIQUID RESIN COMPOSITION 失效
公开(公告)号：JP2001316434A
公开(公告)日：2001-11-13
申请号：JP2000132195
申请日：2000-05-01
申请人： JSR CORP , DSM NV
发明人： MASE MASAHITO , NOMIYAMA HITOMI , YOSHIZAWA JUNJI , KOMIYA ZEN , UKAJI TAKASHI
IPC分类号： G02B6/44 , C03C25/10 , C08F2/44 , C08F2/50 , C08F222/10 , C08F290/06 , C08G18/67 , C08K5/375 , C08L75/16 , C09D4/06 , C09D175/16
摘要： PROBLEM TO BE SOLVED: To provide a curable liquid resin composition to give the cured substance which is excellent in the light resistance, is satisfactory to the thermal stability and is useful as a covering material for optical fibers. SOLUTION: The curable liquid resin composition contains (A) a urthane (meth)acrylate oligomer, (B) an unsaturated polymerizable compound, (C) a photopolymerization initiator, and (D) a compound expressed by formula (1) [wherein, Ra is a hydrogen atom or a 1-4C alkyl group; Rb and Rc are independently a 1-12C alkyl group] or a compound of 2-tert-butyl-6-(3'-tert-butyl-5'- methyl-2'-hydroxybenzyl)-4-methylphenyl acrylate.

10. 发明专利

JP2000273127A CURABLE LIQUID RESIN COMPOSITION 失效
公开(公告)号：JP2000273127A
公开(公告)日：2000-10-03
申请号：JP7720199
申请日：1999-03-23
申请人： JSR CORP , DSM NV
发明人： SUGIMOTO MASANOBU , KOMIYA TAMOTSU , UKAJI TAKASHI
IPC分类号： G02B6/44 , C08F290/06 , C09D4/02
摘要： PROBLEM TO BE SOLVED: To obtain a composition which gives a cured material showing low surface resistance, shows good hardenability and enables high speed coating by forming the composition containing urethane (meth)acrylate, a reactive dilu ent, a polymerization initiator and a conductive powder having a diameter of not more than a specific value and/or an antistatic agent. SOLUTION: A composition of the present invention contains 5-90 pts.wt. of urethane (meth)acrylate, 5-90 pts.wt. of a reactive diluent, 0.1-10 pts.wt. of a polymerization initiator, 0.01-70 pts.wt. of a conductive powder having a diameter of not more than 0.3 μm such as antimony-doped tin oxide, or the like, and/or 0.01-45 pts.wt. of an antistatic agent such as a fatty acid ester of glycerol and the hardened material of the composition shows surface resistance of not more than 1×1012 Ω/(square). The urethane (meth)acrylate includes a reaction product of hydroxyethyl (meth)acrylate and 2,4-tolylene diisocyante. The reactive diluent to be used includes a polymerizable polyfunctional compound represented by the formula such as ethyleneglycol di(meth)acrylate, and the like (wherein R1 and R2 are each hydrogen or methyl; and (n) is 1-100).

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