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1. 发明专利

BR8300720U 未知
公开(公告)号：BR8300720U
公开(公告)日：2005-02-01
申请号：BR8300720
申请日：2003-05-27
申请人： KUO DANIEL SHEN CHOU , CHEN CELINA CHUNTIEN
发明人： KUO DANIEL SHEN CHOU , CHEN CELINA CHUNTIEN
IPC分类号： A61J9/00

2. 发明申请

US20200253504A1 SYSTEMS AND METHODS FOR TISSUE CHARACTERIZATION 审中-公开
公开(公告)号：US20200253504A1
公开(公告)日：2020-08-13
申请号：US16758494
申请日：2017-11-01
申请人： Daniel Shen , Brett Herscher , David Krawzsenek , Kyler Connelly , Michael Baker , R. Maxwell Flaherty , J. Christopher Flaherty
发明人： Daniel Shen , Brett Herscher , David Krawzsenek , Kyler Connelly , Michael Baker , R. Maxwell Flaherty , J. Christopher Flaherty
IPC分类号： A61B5/053 , A61B5/01 , A61B5/00
摘要： Systems for characterizing tissue comprise: a tissue probe comprising a plurality of probe electrodes; a signal generator, a controller, and a user interface. The signal generator is in communication with the probe electrodes for delivering a drive signal to at least one probe electrode. The controller receives a recorded signal from one or more probe electrodes, the recorded signal resulting from delivery of the drive signal through tissue proximate the plurality of probe electrodes. The controller is configured to determine patient-to-patient differences when the tissue probe is proximate a known type of patient tissue and/or bodily fluid, and it produces tissue characterization information based on the recorded signal and the patient-to-patient differences. The user interface provides the tissue characterization information to an operator of the system. Methods of characterizing tissue are also provided.

3. 发明申请

US20170164121A1 Apparatus, System and Method for Reducing Acoustic Feedback Interference Signals 审中-公开
公开(公告)号：US20170164121A1
公开(公告)日：2017-06-08
申请号：US15373389
申请日：2016-12-08
申请人： Bret Herscher , Takahiro Unno , Daniel Shen , Florent Michel , Raphael Michel
发明人： Bret Herscher , Takahiro Unno , Daniel Shen , Florent Michel , Raphael Michel
IPC分类号： H04R25/00
CPC分类号： H04R25/453 , H04R25/402 , H04R25/405 , H04R25/505 , H04R2201/003 , H04R2201/401 , H04R2201/403 , H04R2201/405 , H04R2225/025 , H04R2460/09
摘要： Apparatus, systems and methods for reducing feedback in a hearing aid that includes a transducer configured to detect sound, a sound processor configured to process signals from the transducer, a receiver configured to receive signals outputted from the sound processor, and an acoustic feedback reduction system. The acoustic feedback reduction system is configured to provide signals to the sound processor to produce a null targeting signal steerable toward a source of feedback.

4. 外观设计

USD717959S1 Open ear hearing aid 有权
标题翻译：开耳助听器
公开(公告)号：USD717959S1
公开(公告)日：2014-11-18
申请号：US29486468
申请日：2014-03-30
申请人： Florent Michel , Raphael Michel , Daniel Shen , Bret Herscher , Michael Perry
设计人： Florent Michel , Raphael Michel , Daniel Shen , Bret Herscher , Michael Perry

5. 外观设计

USD693007S1 Open ear hearing aid 有权
标题翻译：开耳助听器
公开(公告)号：USD693007S1
公开(公告)日：2013-11-05
申请号：US29421337
申请日：2012-07-03
申请人： Florent Michel , Raphael Michel , Daniel Shen
设计人： Florent Michel , Raphael Michel , Daniel Shen

6. 发明授权

US08577067B2 Open ear canal hearing aid 有权
标题翻译：打开耳道助听器
公开(公告)号：US08577067B2
公开(公告)日：2013-11-05
申请号：US13865717
申请日：2013-04-18
申请人： Florent Michel , Raphael Michel , Daniel Shen
发明人： Florent Michel , Raphael Michel , Daniel Shen
IPC分类号： H04R25/00
CPC分类号： H04R25/656 , H04R1/42 , H04R25/02 , H04R25/456 , H04R25/48 , H04R25/604 , H04R25/606 , H04R25/652 , H04R25/658 , H04R2225/023 , H04R2460/09 , H04R2460/11 , H04R2460/13 , H04R2460/17
摘要： The invention provides systems and methods for providing hearing aid. An open ear canal hearing aid may be provided in accordance with an embodiment of the invention. The hearing aid may include a part that contains electronic components, a passive amplifier, and a securing mechanism. The securing mechanism may include bristles or balloons. The securing mechanism may have various configurations and be adjustable.
摘要翻译：本发明提供了用于提供助听器的系统和方法。可以根据本发明的实施例提供开放式耳道助听器。助听器可以包括包含电子部件的部件，无源放大器和固定机构。固定机构可以包括刷毛或气球。固定机构可以具有各种构造并且可调节。

7. 发明申请

US20060004191A1 Modified sodium iodide symporter proteins and genes for imaging and cancer therapy 审中-公开
标题翻译：修饰的碘化钠同向转运蛋白和成像和癌症治疗的基因
公开(公告)号：US20060004191A1
公开(公告)日：2006-01-05
申请号：US10519183
申请日：2003-06-25
申请人： Sissy Jhiang , Daniel Shen , Xiaoqin Lin
发明人： Sissy Jhiang , Daniel Shen , Xiaoqin Lin
IPC分类号： C12Q1/68 , C07H21/04 , C07K14/705
CPC分类号： C07K14/705
摘要： The invention provides modified sodium iodide symporter (NIS) proteins, and polynucleotides encoding modified NIS proteins. The modified NIS proteins have a net electrostatic charge more positive than that of corresponding wild-type NIS proteins. Expression of a modified NIS protein in a cell results in higher intracellular concentrations of NIS substrates as compared to equivalent expression of the corresponding wild-type NIS protein in a cell. The invention also provides methods for imaging cells or for therapy of cancer cells, using the modified NIS proteins to facilitate transport of NIS substrates into cells in the body of an individual. Uptake of NIS substrates suitable for either imaging or that have cytotoxic activity, into the cells of the individual that express modified NIS protein facilitate detection of the substrate (for imaging) or killing of the cancer cells (for therapy).
摘要翻译：本发明提供修饰的碘化钠同向转运体（NIS）蛋白质和编码修饰的NIS蛋白质的多核苷酸。修饰的NIS蛋白具有比相应的野生型NIS蛋白更纯正的净静电电荷。与细胞中相应的野生型NIS蛋白的等同表达相比，修饰的NIS蛋白在细胞中的表达导致更高的NIS底物的细胞内浓度。本发明还提供了用于成像细胞或用于治疗癌细胞的方法，其使用经修饰的NIS蛋白促进NIS底物输送到个体体内的细胞中。适用于成像或具有细胞毒活性的NIS底物摄取到表达修饰的NIS蛋白的个体的细胞中有助于检测底物（用于成像）或杀死癌细胞（用于治疗）。

8. 发明授权

US10334370B2 Apparatus, system and method for reducing acoustic feedback interference signals 有权
公开(公告)号：US10334370B2
公开(公告)日：2019-06-25
申请号：US15373389
申请日：2016-12-08
申请人： Bret Herscher , Takahiro Unno , Daniel Shen , Florent Michel , Raphael Michel
发明人： Bret Herscher , Takahiro Unno , Daniel Shen , Florent Michel , Raphael Michel
IPC分类号： H04R25/00
摘要： Apparatus, systems and methods for reducing feedback in a hearing aid that includes a transducer configured to detect sound, a sound processor configured to process signals from the transducer, a receiver configured to receive signals outputted from the sound processor, and an acoustic feedback reduction system. The acoustic feedback reduction system is configured to provide signals to the sound processor to produce a null targeting signal steerable toward a source of feedback.

9. 发明申请

US20140270300A1 Hearing Aid Delivery and Retrieval Platform 审中-公开
标题翻译：助听器交付和检索平台
公开(公告)号：US20140270300A1
公开(公告)日：2014-09-18
申请号：US14291483
申请日：2014-05-30
申请人： Florent Michel , Raphael Michel , Daniel Shen
发明人： Florent Michel , Raphael Michel , Daniel Shen
IPC分类号： H04R25/00
CPC分类号： H04R25/00 , H04R25/60 , H04R25/70 , H04R2225/023 , H04R2460/17
摘要： An apparatus for insertion, positioning and removal of an in-ear-canal hearing aid, comprising a resilient handle, an elongated support member configured to fit into an ear canal, the support member having a first end that is configured to engage the handle and a second end that includes magnetic engagement means configured to removably engage an in-ear-canal hearing aid, and an ear canal ingression stop that is configured to limit travel of the support member and, thereby, the in-ear-canal hearing aid when engaged thereto in the ear canal.
摘要翻译：一种用于插入，定位和移除耳内助听器的装置，包括弹性手柄，构造成装配到耳道中的细长支撑构件，所述支撑构件具有构造成接合手柄的第一端和包括被配置为可移除地接合耳内助听器的磁性接合装置的第二端和被配置为限制支撑构件的行进的耳道入口止挡件，从而限制耳道内助听器与耳道接合。

10. 发明申请

US20130266168A1 Open Ear Canal Hearing Aid 有权
公开(公告)号：US20130266168A1
公开(公告)日：2013-10-10
申请号：US13865717
申请日：2013-04-18
申请人： Florent Michel , Raphael Michel , Daniel Shen
发明人： Florent Michel , Raphael Michel , Daniel Shen
IPC分类号： H04R25/02
CPC分类号： H04R25/656 , H04R1/42 , H04R25/02 , H04R25/456 , H04R25/48 , H04R25/604 , H04R25/606 , H04R25/652 , H04R25/658 , H04R2225/023 , H04R2460/09 , H04R2460/11 , H04R2460/13 , H04R2460/17
摘要： The invention provides systems and methods for providing hearing aid. An open ear canal hearing aid may be provided in accordance with an embodiment of the invention. The hearing aid may include a part that contains electronic components, a passive amplifier, and a securing mechanism. The securing mechanism may include bristles or balloons. The securing mechanism may have various configurations and be adjustable.

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