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1. 发明授权

US08961584B2 Composite stent with regioselective material 有权
标题翻译：具有区域选择性材料的复合支架
公开(公告)号：US08961584B2
公开(公告)日：2015-02-24
申请号：US11641381
申请日：2006-12-18
申请人： Syed F. A. Hossainy , Orlando Padilla , Daryush Mirzaee , Fuh-Wei Tang
发明人： Syed F. A. Hossainy , Orlando Padilla , Daryush Mirzaee , Fuh-Wei Tang
IPC分类号： A61F2/06 , A61F2/915 , A61F2/91 , A61L31/10 , A61L31/16 , A61F2/07
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/075 , A61F2002/91533 , A61F2002/91575 , A61F2230/0013 , A61F2230/0076 , A61F2250/0018 , A61L31/10 , A61L31/16 , A61L2300/606 , Y10S623/916
摘要： A composite stent and a method for making the same are provided.
摘要翻译：提供复合支架及其制造方法。

2. 发明授权

US08298252B2 Flow restoration systems and methods for use 有权
标题翻译：流动恢复系统和使用方法
公开(公告)号：US08298252B2
公开(公告)日：2012-10-30
申请号：US12564892
申请日：2009-09-22
申请人： Jeffrey A. Krolik , Juan Domingo , Daryush Mirzaee , James H. Dreher
发明人： Jeffrey A. Krolik , Juan Domingo , Daryush Mirzaee , James H. Dreher
IPC分类号： A61F2/01 , A61B17/221
CPC分类号： A61B17/3207 , A61B17/221 , A61B17/320725 , A61B2017/00867 , A61B2017/22067 , A61B2017/22069 , A61B2017/22079 , A61B2017/2215 , A61B2017/320741
摘要： Apparatus and methods are provided for removing obstructive material within a body lumen. The apparatus includes a macerator device deployable from a sheath that includes an expandable cage carried by a shaft and within a constraint tube. The shaft is movable relative to the constraint tube for deploying and expanding the cage within a body lumen such that an open end of the cage is oriented towards obstructive material. The cage is advanced to capture the material or the material is directed into the cage using an expandable member expanded beyond the material and retracted to direct the material into the cage. The cage is withdrawn into the constraint tube to compress the cage radially inwardly. Material extending through apertures in the cage are sheared off by a sharpened edge of the constraint tube. The smaller, sheared off particles are then aspirated from the body lumen through the sheath.
摘要翻译：提供了用于去除体腔内的阻塞物质的装置和方法。该装置包括可从护套展开的剥离器装置，其包括由轴承载并在约束管内的可膨胀笼。轴可相对于约束管移动，用于在笼体内展开和膨胀笼，使得保持架的开口端朝向阻塞物质。保持架被推进以捕获材料，或者材料被引导到保持架中，使用膨胀材料膨胀超过材料并缩回以将材料引导到保持架中。将笼子拉出到约束管中，以径向向内压缩笼。延伸通过保持架中的孔的材料被约束管的锋利边缘剪切掉。然后通过护套从体腔吸出较小的剪切颗粒。

3. 发明授权

US08211457B2 Isocyanate coatings for implantable devices and a method of forming the same 有权
标题翻译：用于可植入装置的异氰酸酯涂层及其形成方法
公开(公告)号：US08211457B2
公开(公告)日：2012-07-03
申请号：US12723548
申请日：2010-03-12
申请人： Syed F. A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
发明人： Syed F. A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
IPC分类号： A61F13/00 , A61F2/00 , A61F2/06
CPC分类号： A61L27/34 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/02 , A61L2420/08 , C08L29/04
摘要： Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
摘要翻译：提供用于可植入装置或腔内假体（例如支架）的涂层，包括形成涂层的方法。涂层可用于递送活性成分或活性成分的组合。

4. 发明授权

US07820190B2 Coating for implantable devices and a method of forming the same 有权
标题翻译：用于可植入装置的涂层及其形成方法
公开(公告)号：US07820190B2
公开(公告)日：2010-10-26
申请号：US10751289
申请日：2004-01-02
申请人： Syed F. A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
发明人： Syed F. A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
IPC分类号： A61F2/02
CPC分类号： A61L27/34 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/02 , A61L2420/08 , C08L29/04
摘要： Coatings, particularly primer coatings, for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. The primer coatings include diacrylates and polyacrylates.
摘要翻译：提供了用于可植入装置或腔内假体（例如支架）的涂层，特别是底漆涂层，包括形成涂层的方法。涂层可用于递送活性成分或活性成分的组合。底漆涂料包括二丙烯酸酯和聚丙烯酸酯。

5. 发明申请

US20100168843A1 Coating For Implantable Devices And A Method Of Forming The Same 有权
标题翻译：可植入装置的涂层及其形成方法
公开(公告)号：US20100168843A1
公开(公告)日：2010-07-01
申请号：US12723552
申请日：2010-03-12
申请人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
发明人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
IPC分类号： A61F2/82
CPC分类号： A61L27/34 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/02 , A61L2420/08 , C08L29/04
摘要： Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
摘要翻译：提供用于可植入装置或腔内假体（例如支架）的涂层，包括形成涂层的方法。涂层可用于递送活性成分或活性成分的组合。

6. 发明申请

US20070116856A1 Composite stent with regioselective material 有权
公开(公告)号：US20070116856A1
公开(公告)日：2007-05-24
申请号：US11641236
申请日：2006-12-18
申请人： Syed Hossainy , Orlando Padilla , Daryush Mirzaee
发明人： Syed Hossainy , Orlando Padilla , Daryush Mirzaee
IPC分类号： A61L33/00
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/075 , A61F2002/91533 , A61F2002/91575 , A61F2230/0013 , A61F2230/0076 , A61F2250/0018 , A61L31/10 , A61L31/16 , A61L2300/606 , Y10S623/916
摘要： A composite stent and a method for making the same are provided.

7. 发明申请

US20060280770A1 Coating for implantable devices and a method of forming the same 审中-公开
标题翻译：用于可植入装置的涂层及其形成方法
公开(公告)号：US20060280770A1
公开(公告)日：2006-12-14
申请号：US11506656
申请日：2006-08-17
申请人： Syed Hossainy , Stephen Pacetti , Keith Fong , Vinayak Bhat , Deborra Sanders Millare , Judy Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
发明人： Syed Hossainy , Stephen Pacetti , Keith Fong , Vinayak Bhat , Deborra Sanders Millare , Judy Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
IPC分类号： A61K9/22
CPC分类号： A61L27/34 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/02 , A61L2420/08 , C08L29/04
摘要： Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
摘要翻译：提供用于可植入装置或腔内假体（例如支架）的涂层，包括形成涂层的方法。涂层可用于递送活性成分或活性成分的组合。

8. 发明申请

US20050033411A1 Surface features of an implantable medical device 审中-公开
标题翻译：可植入医疗器械的表面特征
公开(公告)号：US20050033411A1
公开(公告)日：2005-02-10
申请号：US10911968
申请日：2004-08-04
申请人： Steven Wu , Sameer Harish , Deborra Sanders-Millare , Judy Guruwaiya , Daryush Mirzaee , Syed Hossainy , Charlene Chen
发明人： Steven Wu , Sameer Harish , Deborra Sanders-Millare , Judy Guruwaiya , Daryush Mirzaee , Syed Hossainy , Charlene Chen
IPC分类号： A61F2/00 , A61F2/06 , A61F2/90
CPC分类号： A61F2/0077 , A61F2/848 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2230/0013 , A61F2250/0067 , A61F2250/0068 , Y10S623/901
摘要： An implantable medical device, such as a stent or graft, having asperities on a designated region of its outer surface is disclosed. The asperities can serve to improve retention of one or more layers of a coating on the device and to increase the amount of coating that can be carried by the device. The asperities can be formed by using a stream of pressurized grit to roughen the surface. The asperities can also be formed by removing material from the outer surface, for example, by chemical etching with or without a patterned mask. Alternatively, the asperities can be formed by adding material to the outer surface, for example, by welding powder particles to the outer surface or sputtering.
摘要翻译：公开了一种在其外表面的指定区域上具有凹凸的可植入医疗装置，例如支架或移植物。粗糙度可用于改善设备上一层或多层涂层的保留性并增加该装置可承载的涂层量。可以通过使用加压砂粒流粗糙表面来形成凹凸。也可以通过从外表面去除材料来形成凹凸，例如通过具有或不具有图案化掩模的化学蚀刻来形成。或者，可以通过向外表面添加材料，例如通过将粉末颗粒焊接到外表面或溅射来形成凹凸。

9. 发明授权

US06485500B1 Emboli protection system 有权
标题翻译： Emboli保护系统
公开(公告)号：US06485500B1
公开(公告)日：2002-11-26
申请号：US09531740
申请日：2000-03-21
申请人： Arkady Kokish , Daryush Mirzaee , Eric J. Penn , Benjamin C. Huter , Kent C. B. Stalker , Gregg A. Jackson
发明人： Arkady Kokish , Daryush Mirzaee , Eric J. Penn , Benjamin C. Huter , Kent C. B. Stalker , Gregg A. Jackson
IPC分类号： A61M2900
CPC分类号： A61M25/104 , A61M2025/0079 , A61M2025/1013 , A61M2025/105 , A61M2025/1052 , A61M2025/1093 , A61M2025/1095
摘要： The emboli protection system provides one or more inflatable blocking balloons for isolation of a section of a blood vessel to prevent migration of emboli from the section during an interventional procedure, and fluid infusion and evacuation ports for flushing emboli from the isolated section. One embodiment provides for a distal blocking balloon catheter, over which an interventional device can be introduced, and a proximal blocking balloon catheter to be introduced over the interventional device for isolating a portion of a blood vessel to be treated. The blocking balloons can be perforated to provide the infusion ports, and thrombolytic inflation fluid may be used to break down and dissolve thrombus and plaque in the isolated portion of the blood vessel. The interventional therapeutic device such as an angioplasty balloon catheter may be incorporated into the distal blocking balloon catheter, or the distal and blocking proximal balloon catheters can be incorporated with the interventional therapeutic device together in one device. Infusion ports may also be provided in either or both of the distal and proximal blocking catheters.
摘要翻译：栓塞保护系统提供一个或多个可膨胀的阻塞气球，用于隔离血管的一部分，以防止在介入手术过程中栓塞从该部分移位，以及用于从隔离部分冲洗栓塞的流体输注和排出口。一个实施例提供远端阻塞气囊导管，介入装置可以在其上引入，以及近端阻塞气囊导管，其被引入到介入装置上，用于隔离待治疗血管的一部分。阻塞气囊可以被穿孔以提供输注口，并且可以使用溶栓膨胀流体来分解和溶解血管的孤立部分中的血栓和斑块。诸如血管成形术气囊导管的介入治疗装置可以并入到远端阻塞气囊导管中，或者远端和阻塞近端球囊导管可以与介入治疗装置并入一个装置中。输液口也可以设置在远端和近端阻塞导管中的一个或两者中。

10. 发明授权

US08652501B2 Primer layer coatings of a material with a high content of hydrogen bonding groups for implantable devices and a method of forming the same 有权
标题翻译：用于可植入装置的具有高含量氢键基团的材料的底漆层涂层及其形成方法
公开(公告)号：US08652501B2
公开(公告)日：2014-02-18
申请号：US13427608
申请日：2012-03-22
申请人： Syed F. A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
发明人： Syed F. A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
IPC分类号： A61F13/00 , A61F2/06
CPC分类号： A61L27/34 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/02 , A61L2420/08 , C08L29/04
摘要： Primer coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The primer coatings can include a material with a high content of hydrogen bonding groups, such as some types of epoxy polymers and melamine formaldehydes. Coatings subsequently disposed over the primer coating can be used for the delivery of an active ingredient or a combination of active ingredients.
摘要翻译：提供用于可植入装置或腔内假体（例如支架）的底漆涂层，包括形成涂层的方法。底漆涂层可以包括具有高含量氢键基团的材料，例如一些类型的环氧聚合物和三聚氰胺甲醛。随后布置在底漆涂层上的涂层可用于递送活性成分或活性成分的组合。

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