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1. 发明专利

AU2573799A Ion separation using a surface-treated xerogel 未知
公开(公告)号：AU2573799A
公开(公告)日：1999-08-23
申请号：AU2573799
申请日：1999-02-03
申请人： INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK INC
发明人： YANG ARTHUR JING-MIN
IPC分类号： B01J20/10 , B01D15/00 , B01J20/32 , B01J39/14 , C09K3/32 , B01J13/00
摘要： Amorphous, nanoporous silica gel having an open channel structure may be surface modified at higher loading of surface modifying ligands, e.g., 7.5 mmole per gram, than known nanoporous silica gels. In one embodiment, an amorphous silica gel has a bimodal pore size distribution of pores at about 10 nanometers and at about 10 microns, and a bulk density of about 0.2 to about 0.25 g/ml. Surface modification with functionalized ligand groups, effective for selective adsorption or reaction catalysis, is achieved by gelling silica sol solution to form a wet silica gel, maintaining the gel at a relatively low elevated temperature in a moist state to obtain a wet nanoporous silica gel having a plurality of open channels within the gel structure and silanol groups on the surface and reacting the surface silanol groups with the ligand group to introduce the functionalized group. The surface modifying reaction may be carried out concurrently with the gelling of a silica precursor in an aqueous alcoholic medium. 3-mercaptopropyltrialkoxysilane is an exemplary ligand introducing compound. The chemically surface modified gel may be used, for example, to remove or concentrate metallic substances in a liquid, or to separate two or more metallic impurities from a mixture thereof, or for cleanup of oil or chemical contaminants from the surface of a body of water.

2. 发明申请

WO2005117844A3 MUCOADHESIVE NANOCOMPOSITE DELIVERY SYSTEM 审中-公开
公开(公告)号：WO2005117844A3
公开(公告)日：2005-12-15
申请号：PCT/US2005/017638
申请日：2005-05-20
申请人： INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK, INC. , PARK, Yoon, Jeong , YANG, Arthur, Jin-Ming , DAVID, Allan, Emerson , ZHANG, Ruiyun
发明人： PARK, Yoon, Jeong , YANG, Arthur, Jin-Ming , DAVID, Allan, Emerson , ZHANG, Ruiyun
IPC分类号： A61K9/14
摘要： A nanocomposite delivery system uses chitosan as a mucoadhesive material encapsulated in a surface modified network of colloidal nanoporous nanoparticles, such as silica, or other colloid-forming materials, especially metal oxides. Drug delivery systems may be provided by binding a drug to the chitosan/silica nanocomposite, typically by adding a drug or other active agent during in-situ gellation of colloidal silica. When the active agent is, for example, amoxicillin or other antiobiotic agent, the drug delivery system may be used in the treatment of stomach ulcers, for example.

3. 发明申请

WO2018144922A1 FACILE CLAY EXFOLIATION USING POLYMER SILICONE SURFACTANTS 审中-公开
公开(公告)号：WO2018144922A1
公开(公告)日：2018-08-09
申请号：PCT/US2018/016712
申请日：2018-02-02
申请人： INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK, INC.
发明人： YANG, Arthur Jing-Min , LAI, Sun-Mou , DOMSZY, Roman C. , WANG, Tsung-Jen
IPC分类号： C01B33/44 , C09C1/42
摘要： The present invention is directed to processes for preparing a silicone surfactant intercalated clay and a polymer-clay nanocomposite. The processes use silicone surfactants having a molecular weight in the range of 10,000 to 100,000 Dalton to achieve fully exfoliating clay structures. Using these macromolecular silicone surfactants, along with the engineered control of the processing pH and drying stress conditions, this invention provides simple and low-cost methods of making a fully-exfoliated polymer-clay nanocomposite.

4. 发明申请

WO2004081188A2 NON-TOXIC MEMBRANE-TRANSLOCATING PEPTIDES 审中-公开
标题翻译：非毒性膜转录肽
公开(公告)号：WO2004081188A2
公开(公告)日：2004-09-23
申请号：PCT/US2004/007145
申请日：2004-03-10
申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN , INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK, INC. , PARK, Yoon, Jeong , LIANG, Jun, Feng , YANG, Victor, C. , CHANG, Li-Chien
发明人： PARK, Yoon, Jeong , LIANG, Jun, Feng , YANG, Victor, C. , CHANG, Li-Chien
IPC分类号： C12N
CPC分类号： C12N15/87 , A61K38/168 , A61K47/64 , A61K47/645 , A61K48/0008 , A61K49/0041 , A61K49/0043 , A61K49/0056 , C07K7/06 , C07K7/08 , C07K14/461 , C07K2319/03
摘要： Compositions for transport across a biological membrane include a membrane-translocating LMWP peptide and a cargo molecule. Methods for transporting a cargo molecule across a biological membrane are also described.
摘要翻译：用于在生物膜上运输的组合物包括膜易位的LMWP肽和货物分子。还描述了将货物分子穿过生物膜运送的方法。

5. 发明申请

WO2009134425A1 SUPERINSULATION WITH NANOPORES 审中-公开
标题翻译：与纳米级的监督
公开(公告)号：WO2009134425A1
公开(公告)日：2009-11-05
申请号：PCT/US2009/002693
申请日：2009-05-01
申请人： INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK, INC. , YANG, Arthur, J.
发明人： YANG, Arthur, J.
IPC分类号： B65D39/00 , C04B38/02
CPC分类号： C08F12/08 , C04B26/10 , C04B38/103 , C04B2111/00853 , C04B2111/40 , C08G18/14 , C08G2101/00 , C08J9/122 , C08J2201/032 , C08J2203/06 , C08J2205/042 , C08J2325/00 , C08J2375/04 , C04B14/10 , C04B24/2676 , C04B24/282 , C04B38/0051 , C04B38/0054
摘要： This invention relates to the field of thermal insulation. In particular, the invention describes superinsulation articles having a desired porosity, reduced pore size and cost-effective methods for manufacturing such articles. In one aspect of the present invention, the article may comprise a material system with at least about 20 % porosity. In a further aspect of the invention, an article may comprise greater than about 25 % of nanopores having a pore size no greater than about 1500 nanometers in its shortest axis.
摘要翻译：本发明涉及隔热领域。特别地，本发明描述了具有所需孔隙率，减小的孔径和用于制造这种制品的成本有效的方法的超临界制品。在本发明的一个方面，制品可以包括具有至少约20％孔隙率的材料体系。在本发明的另一方面，制品可包含大于约25％的孔径在其最短轴上不大于约1500纳米的纳米孔。

6. 发明申请

WO2009020577A2 INNOVATIVE FORMULATION FOR ORAL INSULIN DELIVERY 审中-公开
标题翻译：口服胰岛素的创新配方
公开(公告)号：WO2009020577A2
公开(公告)日：2009-02-12
申请号：PCT/US2008/009365
申请日：2008-08-04
申请人： INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK, INC. , DAVID, Allan, E. , YANG, Arthur, J. , PARK, Yoon, Jeong , CHANG, Li-chien , YANG, Victor, C.
发明人： DAVID, Allan, E. , YANG, Arthur, J. , PARK, Yoon, Jeong , CHANG, Li-chien , YANG, Victor, C.
IPC分类号： C07K14/62
CPC分类号： C07K14/62 , A61K38/00
摘要： The present invention provides for an encapsulated, mucoadhesive oral formulation for hormones, such as insulin, and methods of using such formulations.
摘要翻译：本发明提供了用于激素例如胰岛素的胶囊包封粘膜粘附剂口服制剂，以及使用此类制剂的方法。

7. 发明申请

WO2008057382A2 NANOPORE REACTIVE ADSORBENTS FOR THE HIGH-EFFICIENCY REMOVAL OF WASTE SPECIES 审中-公开
标题翻译：用于高效除去废物的纳米反应性吸附剂
公开(公告)号：WO2008057382A2
公开(公告)日：2008-05-15
申请号：PCT/US2007/023069
申请日：2007-10-31
申请人： INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK INC. , DOMSZY, Roman , LEE, Yun, Han
发明人： DOMSZY, Roman , LEE, Yun, Han
IPC分类号： A62D3/30 , A62D101/43
CPC分类号： C22B3/24 , B01J20/048 , B01J20/103 , B01J20/26 , B01J20/262 , B01J20/28007 , B01J20/2808 , B01J39/09 , B01J39/12 , B01J41/10 , B01J47/018 , B01J2220/46 , B82Y30/00 , C02F1/288 , C02F2101/20 , C22B13/045 , Y02P10/234
摘要： A nanopore reactive adsorbent composite material, which may be a porous adsorbent comprising a chemically surface modified gel, has a composition and micro structure, which integrals ion exchange components such as hydroxy apatite.
摘要翻译：可以是包含化学表面改性凝胶的多孔吸附剂的纳米孔反应性吸附剂复合材料具有积分离子交换组分如羟基磷灰石的组成和微观结构。

8. 发明申请

WO2007050100A2 IMMOBILIZED ENZYMES AND PROCESSES FOR PREPARING AND USING SAME 审中-公开
标题翻译：固定化酶及其制备和使用过程
公开(公告)号：WO2007050100A2
公开(公告)日：2007-05-03
申请号：PCT/US2005/042657
申请日：2005-11-23
申请人： INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK, INC. , DAVID, Allan , YANG, Arthur
发明人： DAVID, Allan , YANG, Arthur
IPC分类号： C12N11/14
CPC分类号： C12N11/14 , C12N9/54 , C12P21/06
摘要： A highly loaded immobilized enzyme conjugate is prepared from a nanopore silica gel support. The enzyme may be immobilized in an amount, based on the silica gel support, of at least about 500 mg enzyme per gram of silica gel. The immobilized enzyme conjugate may be prepared by a method which includes the following steps: (a) surface modifying silicic acid by reacting the silicic acid with a basic aminoalkylsilane in solution in an alcoholic medium, wherein the amount of the basic aminoalkylsilane is sufficient to raise the pH of the solution to induce gelation and form a chemically surface-modified silica gel; (b) activating the chemically surface-modified silica gel by reaction with a cross-linking agent; and (c) contacting the activated chemically surface-modified silica gel with an enzyme. Immobilized thermolysin has been used to prepare a low molecular weight protamine with high efficiency.
摘要翻译：从纳米孔硅胶载体制备高负载的固定化酶缀合物。基于硅胶载体，酶可以固定在至少约500mg酶/克硅胶的量。可通过包括以下步骤的方法制备固定化酶缀合物：（a）通过硅酸与碱性氨基烷基硅烷在醇类介质中的溶液中反应来表面改性硅酸，其中碱性氨基烷基硅烷的量足以提高该溶液的pH诱导凝胶化并形成化学表面改性的硅胶; （b）通过与交联剂反应活化化学表面改性的硅胶; 和（c）使活化的化学表面改性的硅胶与酶接触。固定的嗜热菌蛋白酶已被用于高效率地制备低分子量鱼精蛋白。

9. 发明申请

WO2014172645A2 ADVANCED THERMAL INSULATION BY PORE MORPHOLOGY CONTROL IN FOAMING 审中-公开
标题翻译：泡沫形态控制的先进隔热技术
公开(公告)号：WO2014172645A2
公开(公告)日：2014-10-23
申请号：PCT/US2014/034663
申请日：2014-04-18
申请人： INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK, INC.
发明人： YANG, Arthur, Jing-min
IPC分类号： B29C45/57
CPC分类号： B29C44/468
摘要： A foam extrusion slot die is provided, comprising a plurality of parallel dividers extending transversely across the slot, wherein the plurality of dividers define a plurality of adjacent rectangular slit openings each having a length extending perpendicularly across the lateral length of the slot die. An article of manufacture is provided, comprising a polymer material system with at least 95% porosity comprising greater than 10%> asymmetrical pores. A method an article of manufacture is provided, comprising: extruding polymer material through an extruder die opening having an output orifice partitioned by a plurality of parallel dividers defining a plurality of adjacent slit openings each having a vertical height greater than a lateral width.
摘要翻译：提供了一种泡沫挤出狭缝模具，其包括多个横向延伸穿过狭缝的平行分隔器，其中多个分隔器限定多个相邻的矩形狭缝开口，每个狭缝开口具有垂直于横向延伸的长度槽模的长度。提供了一种制造物品，其包含具有至少95％孔隙率的聚合物材料体系，其包含大于10％不对称的毛孔。提供了一种制造物品的方法，包括：挤出聚合物材料通过挤出机模具开口，所述挤出机模具开口具有由多个平行分隔器分隔的输出孔，所述多个平行分隔器限定多个相邻的狭缝开口，每个狭缝开口具有大于横向宽度的竖直高度。 p>

10. 发明申请

WO2008039228A1 NANOENGINEERED COMPOSITE DEFOG COATING 审中-公开
标题翻译：纳米复合材料定义涂料
公开(公告)号：WO2008039228A1
公开(公告)日：2008-04-03
申请号：PCT/US2007/003534
申请日：2007-02-08
申请人： INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK, INC. , ZHANG, Ruiyun , YANG, Arthur, J.
发明人： ZHANG, Ruiyun , YANG, Arthur, J.
IPC分类号： C08G18/67
CPC分类号： C09D175/16 , C08G18/672 , C08G2290/00 , Y10T428/31504 , Y10T428/31507 , Y10T428/31649 , Y10T428/31797 , Y10T428/31891 , Y10T428/31928 , Y10T428/31935
摘要： An engineered nano-composite coating may include hydrophobic an hydrophilic domains, may be applied to transparent and non-transparent substrates using a continuous process, may be UV curable and may impart antifogging characteristics to the substrate.
摘要翻译：工程化的纳米复合涂层可以包括疏水性亲水区域，可以使用连续方法施加到透明和非透明基底上，可以是UV固化的并且可以赋予基底防雾特性。

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