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1. 发明专利

AR020190A1 COMPOSICIONES RELACIONADAS CON ESTEAROIL-COA DESATURASA HUMANA Y METODOS PARA TRATAR DESORDENES DE LA PIEL 未知
公开(公告)号：AR020190A1
公开(公告)日：2002-05-02
申请号：ARP990104075
申请日：1999-08-13
申请人： JOHNSON MICHAEL H
IPC分类号： C07K16/40 , C12N9/02 , C12Q1/68 , C12Q1/6809 , C12Q1/6883 , C12N15/85 , A61K39/395 , A61K48/00 , C12N5/10 , G01N33/573
摘要： Esta invencion provee una molécula de ácido nucleico que codifica la estearoil-CoA desaturasa humana, y la proteína aislada codificada por la misma. Estainvencion porvee también un método de diagnostico de un sujeto humano para un desorden de la pielcaracterizado por un nivel anormal de expresion de estearoil-CoA desaturasa. Esta invencion provee además un método para determinar si un agente aumenta el nivel de expresion de la estearoil-CoA desaturasa humana en lascélulas de la piel que ya expresan la misma. Esta invencion provee además métodos para determinar si un agente aumenta o disminuye el nivel de expresion o deactividad de la estearoil-CoA desaturasa humana en las células de la piel que ya expresan la misma. Esta invencion provee además composiciones farmacéuticaspara tratar desordenes de la piel humana caracterizados por una expresion y/o actividad anormal de estearoil-CoA desaturasa, y métodos de tratamientorelacionados. Finalmente, esta invencion provee anticuerpos relacionados, vectores para terapia génica y ratones trasn-génicos.

2. 发明申请

WO2013066562A3 POLARIZABLE NANOPARTICLES AND ELECTRORHEOLOGICAL FLUID COMPRISING SAME 审中-公开
标题翻译：可偏振的纳米颗粒和包含该纳米颗粒的电流变流体
公开(公告)号：WO2013066562A3
公开(公告)日：2013-07-18
申请号：PCT/US2012058952
申请日：2012-10-05
申请人： BAKER HUGHES INC , MAZYAR OLEG A , CHAKRABORTY SOMA , BUSSEAR TERRY R , JOHNSON MICHAEL H
发明人： MAZYAR OLEG A , CHAKRABORTY SOMA , BUSSEAR TERRY R , JOHNSON MICHAEL H
IPC分类号： B82B1/00 , B22F1/02 , C10M171/00
CPC分类号： B22F1/02 , B22F1/0022 , B82Y30/00 , C10M171/001 , C10M2201/05 , C10M2203/1006 , C10M2203/1085 , C10N2210/01 , C10N2210/03 , C10N2210/04 , C10N2210/06 , C10N2210/07 , C10N2210/08 , C10N2220/082 , C10N2230/08 , C10N2230/10 , C10N2230/60 , C10N2240/201 , C22C26/00 , C22C2026/001 , C22C2026/002 , Y10T428/2991
摘要： A nanoparticle composition includes a metal nanoparticle, and a continuous dielectric coating on a surface of the metal nanoparticle, the nanoparticle composition being a dielectric material. A nanoparticle is in addition the reaction product of an organometallic compound. An electrorheological fluid comprises the nanoparticle composition and a dielectric fluid, and a method of making an electrorheological fluid is also disclosed.
摘要翻译：纳米粒子组合物包含金属纳米粒子和金属纳米粒子表面上的连续介电涂层，纳米粒子组合物为介电材料。另外纳米颗粒是有机金属化合物的反应产物。电流变流体包含纳米颗粒组合物和介电流体，并且还公开了制造电流变流体的方法。

3. 发明申请

WO2012112261A3 SAND SCREEN, EXPANDABLE SCREEN AND METHOD OF MAKING 审中-公开
标题翻译： SAND屏幕，可扩展屏幕和制作方法
公开(公告)号：WO2012112261A3
公开(公告)日：2012-10-26
申请号：PCT/US2012022318
申请日：2012-01-24
申请人： BAKER HUGHES INC , GUEST RANDALL V , JOHNSON MICHAEL H , HUBER KIRK J
发明人： GUEST RANDALL V , JOHNSON MICHAEL H , HUBER KIRK J
IPC分类号： B01D39/02 , B01D29/11 , B01D35/02 , B01D39/10 , B01D39/14
CPC分类号： B21F27/18 , B01D39/12 , B21F45/008
摘要： An expandable screen includes, a body constructed of one or more strands of a shape memory material randomly distributed in a mat structure, the body is stable at a first volume and expandable to a second volume upon a change in environment.
摘要翻译：可膨胀屏幕包括由随机分布在垫结构中的形状记忆材料的一股或多股构成的主体，所述身体在第一体积下是稳定的，并且在环境变化时可扩展到第二体积。

4. 发明申请

WO2012112246A2 POLYMERIC COMPONENT AND METHOD OF MAKING 审中-公开
标题翻译：聚合物组分和制备方法
公开(公告)号：WO2012112246A2
公开(公告)日：2012-08-23
申请号：PCT/US2012/021273
申请日：2012-01-13
申请人： BAKER HUGHES INCORPORATED , GUEST, Randall V. , JOHNSON, Michael H. , HUBER, Kirk J.
发明人： GUEST, Randall V. , JOHNSON, Michael H. , HUBER, Kirk J.
IPC分类号： D04H3/16 , D04H3/14 , D04H3/10
CPC分类号： B32B5/02 , B32B27/12 , D04H3/12 , D04H3/14 , D04H3/16 , Y10T428/2481
摘要： A method of making a polymeric component includes, extruding one or more strands of a polymer, halting curing of the one or more strands, forming a mat with the extruded one or more strands, bonding the one or more strands to one another at points of contact therebetween, and curing the one or more strands.
摘要翻译：制造聚合物组分的方法包括挤出一股或多股聚合物，停止一根或多根股线的固化，用挤出的一根或多根股线形成垫子，将一根或多根股线粘合或在它们之间的接触点处彼此更多的股线，以及固化一个或多个股线。

5. 发明申请

WO2012005979A3 WELLBORE CENTRALIZER FOR TUBULARS 审中-公开
标题翻译：井式集中器用于管件
公开(公告)号：WO2012005979A3
公开(公告)日：2012-04-26
申请号：PCT/US2011041789
申请日：2011-06-24
申请人： BAKER HUGHES INC , BARNARD JASON J , HORNER DONALD N , JOHNSON MICHAEL H
发明人： BARNARD JASON J , HORNER DONALD N , JOHNSON MICHAEL H
IPC分类号： E21B17/10
CPC分类号： E21B17/1078 , E21B17/10
摘要： A tubular centralizer is secured to the tubular for run in. The profile for run in is small so that damage to the centralizer is minimized during run in. When the string is in position the centralizer is actuated to change shape or volume to engage the surrounding borehole to centralize the tubular for subsequent operations such as cementing or in the case of screens for gravel packing. The centralizer can be a shape memory material that is initially compressed at above its transition temperature to hold the smaller shape. At the desired location after run in it is brought above the transition temperature and changes back to the original shape or volume to centralize the tubular string. The structure can be spaced ring segments or a cohesive ring structure with an undulating profile or radiating blades to create flow spaces in the annulus where it is deployed for flow of a sealing material or gravel, for example.
摘要翻译：一个管状扶正器固定在管道上以便进入。用于运行的轮廓很小，因此在运行期间对扶正器的损坏最小化。当绳索处于适当位置时，扶正器被致动以改变形状或体积以接合周围钻孔以将管状物集中以用于随后的操作，例如固井或用于砾石充填的筛网。扶正器可以是形状记忆材料，其最初在其转变温度以上被压缩以保持较小的形状。在运行之后，在所需的位置处，其在转变温度以上并且变回到原始形状或体积以集中管柱。例如，该结构可以是具有波状轮廓的间隔环段或粘性环结构或辐射叶片，以便在其中部署用于密封材料或砾石的流动的环形空间中产生流动空间。

6. 发明申请

WO2012009098A3 BALL SEAT HAVING COLLAPSIBLE HELICAL SEAT 审中-公开
标题翻译：球座具有可折叠螺旋座椅
公开(公告)号：WO2012009098A3
公开(公告)日：2012-04-12
申请号：PCT/US2011040803
申请日：2011-06-17
申请人： BAKER HUGHES INC , KORKMAZ LALE , JOHNSON MICHAEL H , PORTER ANDRE J
发明人： KORKMAZ LALE , JOHNSON MICHAEL H , PORTER ANDRE J
IPC分类号： E21B34/14 , E21B34/06 , E21B34/10
CPC分类号： F16K15/044 , E21B23/04 , F16K15/183 , F16K17/0406
摘要： Apparatuses for restricting fluid flow through a well conduit comprise a tubular member having a helically-shaped seat member disposed within the tubular member. The helically-shaped seat member comprises first and second ends, a first position in which the first and second ends relative to each other to provide a first diameter opening through the helically-shaped seat member for receiving a plug element, and a second position in which the second end is disposed axially below and radially outward relative to the first end to provide a second diameter opening through the helically seat member, the second diameter being greater than the first diameter thereby facilitating the plug element passing through the helically-shaped seat.
摘要翻译：用于限制通过井导管的流体流动的装置包括管状构件，该管状构件具有布置在管状构件内的螺旋形座椅构件。螺旋形座椅构件包括第一端和第二端，第一位置中第一端和第二端相对于彼此以提供穿过螺旋形座构件的第一直径开口以用于接收插塞元件，并且第二位置在第一位置所述第二端相对于所述第一端在轴向下方且径向向外布置，以提供穿过所述螺旋形座部件的第二直径开口，所述第二直径大于所述第一直径，由此便于所述插塞元件穿过所述螺旋形座。

7. 发明申请

WO2012044810A3 ANISOTROPIC FILTRATION MEDIA AND METHOD OF MAKING 审中-公开
公开(公告)号：WO2012044810A3
公开(公告)日：2012-04-05
申请号：PCT/US2011/053964
申请日：2011-09-29
申请人： BAKER HUGHES INCORPORATED , CARREJO, Nicholas , JOHNSON, Michael H. , GUEST, Randall V.
发明人： CARREJO, Nicholas , JOHNSON, Michael H. , GUEST, Randall V.
IPC分类号： B01D39/14 , B01D39/20 , B01D46/00 , B01D53/00
摘要： A method of making an anisotropic filtration media includes, foaming a media, straining the media in a selected direction, and relieving strain of the media in the selected direction.

8. 发明申请

WO2011119316A1 VARIABLE Tg SHAPE MEMORY POLYURETHANE FOR WELLBORE DEVICES 审中-公开
标题翻译：用于井筒设备的可变Tg形状记忆聚氨酯
公开(公告)号：WO2011119316A1
公开(公告)日：2011-09-29
申请号：PCT/US2011/027346
申请日：2011-03-07
申请人： BAKER HUGHES INCORPORATED , CARREJO, Nicholas , JOHNSON, Michael, H.
发明人： CARREJO, Nicholas , JOHNSON, Michael, H.
IPC分类号： E21B43/08 , E21B43/10
CPC分类号： E21B41/00 , C08L2201/12 , C09K3/1021 , E21B43/08 , E21B43/108 , F03G7/065 , Y10T29/49865 , Y10T156/1005
摘要： Wellbore devices for use in filtration, wellbore isolation, production control, lifecycle management and wellbore construction may include at least a first and a second shape-memory material each having a an altered geometric position and each an original geometric position. Each shape- memory material may include a polyurethane material held in the altered geometric run-in position at a temperature below glass transition temperature (T g ), where the T g s and/or the respective slope changes of the first and second polyurethane materials are different. Once the wellbore device is in place downhole and the first and second shape-memory materials are subjected to temperatures above their T g s, the materials will deploy and expand to recovered geometric positions at or near their original geometric positions to perform their filtration, isolation, control or other function. These deployments or expansions may occur at different times or rates.
摘要翻译：用于过滤，井眼隔离，生产控制，生命周期管理和井眼结构的井筒装置可以包括至少第一和第二形状记忆材料，每个具有改变的几何位置和每个原始几何位置。每种形状记忆材料可以包括在低于玻璃化转变温度（Tg）的温度下保持在改变的几何入口位置的聚氨酯材料，其中第一和第二聚氨酯材料的Tg和/或相应的斜率变化是不同的。一旦井眼装置在井下就位，并且第一和第二形状记忆材料经受高于其Tg的温度，则材料将在其原始几何位置处或附近展开并扩展至恢复的几何位置，以执行其过滤，隔离，控制或其他功能。这些部署或扩展可能会发生在不同的时间或速度。

9. 发明申请

WO2010141199A3 PERMEABILITY FLOW BALANCING WITHIN INTEGRAL SCREEN JOINTS AND METHOD 审中-公开
标题翻译：渗透性流动平衡与整体筛选接头和方法
公开(公告)号：WO2010141199A3
公开(公告)日：2011-02-03
申请号：PCT/US2010034760
申请日：2010-05-13
申请人： BAKER HUGHES INC , JOHNSON MICHAEL H , KIM NAMHYO
发明人： JOHNSON MICHAEL H , KIM NAMHYO
IPC分类号： E21B43/08
CPC分类号： E21B43/12
摘要： A borehole system having a permeability controlled flow profile including a tubular string; one or more permeability control devices disposed in the string; and the plurality of permeability control devices being selected to produce particular pressure drops for fluid entering or exiting various discrete locations along the string and method.
摘要翻译：一种钻孔系统，其具有包括管状柱的渗透性控制的流动轮廓; 设置在琴弦中的一个或多个磁导率控制装置; 并且所述多个磁导率控制装置被选择以产生流体沿着弦和方法进入或离开各种离散位置的特定压降。

10. 发明申请

WO2010141195A3 PERMEABILITY FLOW BALANCING WITHIN INTEGRAL SCREEN JOINTS AND METHOD 审中-公开
标题翻译：渗透性流动平衡与整体筛选接头和方法
公开(公告)号：WO2010141195A3
公开(公告)日：2011-02-03
申请号：PCT/US2010034747
申请日：2010-05-13
申请人： BAKER HUGHES INC , JOHNSON MICHAEL H , KIM NAMHYO
发明人： JOHNSON MICHAEL H , KIM NAMHYO
IPC分类号： E21B43/08
CPC分类号： E21B43/2406
摘要： A method for uniform heating of a formation including applying a high temperature fluid to a tubular located within an open hole formation borehole; modifying a permeability of the tubular along its length by reducing permeability at a heel of the borehole and by increasing permeability towards a toe of the borehole; and impeding annular movement of the heated fluid by radially extending one or more baffles from the tubular.
摘要翻译：一种用于均匀加热地层的方法，包括将高温流体施加到位于开孔形成钻孔内的管状物; 通过减少钻孔后跟处的渗透性并增加对钻孔的趾部的渗透性来改变管状物沿其长度的渗透性; 并且通过从管状物径向延伸一个或多个挡板来阻止被加热流体的环形运动。

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