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1. 发明申请

US20120289932A1 DEVICE AND METHOD FOR COMBINING A TREATMENT AGENT AND A GEL 失效
公开(公告)号：US20120289932A1
公开(公告)日：2012-11-15
申请号：US13559438
申请日：2012-07-26
申请人： Charles D. Claude , Paul J. Kawula , Syed Faiyaz Ahmed Hossainy , KimChi Tran
发明人： Charles D. Claude , Paul J. Kawula , Syed Faiyaz Ahmed Hossainy , KimChi Tran
IPC分类号： A61M5/00 , A61P9/00 , A61P35/00 , A61K38/19
CPC分类号： A61K9/0024 , A61K9/06
摘要： A method including introducing a treatment agent at a treatment site within a mammalian host; and introducing a bioerodable gel material at the treatment site. An apparatus including a first annular member having a first lumen disposed about a length of the first annular member and a first entry port at a proximal end of the first annular member, and a second annular member coupled to the first annular member having a second lumen disposed about a length of the second annular member and a second entry port at a proximal end of the second annular member, wherein the first annular member and the second annular member are positioned to allow a combining of treatment agents introduced through each annular member at the treatment site.

2. 发明申请

US20080114293A1 DEVICE AND METHOD FOR COMBINING A TREATMENT AGENT AND A GEL 有权
标题翻译：用于组合治疗剂和凝胶的装置和方法
公开(公告)号：US20080114293A1
公开(公告)日：2008-05-15
申请号：US12013286
申请日：2008-01-11
申请人： Charles Claude , Paul Kawula , Syed Hossainy , Kimchi Tran
发明人： Charles Claude , Paul Kawula , Syed Hossainy , Kimchi Tran
IPC分类号： A61M37/00
CPC分类号： A61K9/0024 , A61K9/06
摘要： A method including introducing a treatment agent at a treatment site within a mammalian host; and introducing a bioerodable gel material at the treatment site. An apparatus including a first annular member having a first lumen disposed about a length of the first annular member and a first entry port at a proximal end of the first annular member, and a second annular member coupled to the first annular member having a second lumen disposed about a length of the second annular member and a second entry port at a proximal end of the second annular member, wherein the first annular member and the second annular member are positioned to allow a combining of treatment agents introduced through each annular member at the treatment site.
摘要翻译：一种方法，包括在哺乳动物宿主内的处理部位引入处理剂; 并在处理部位引入可生物浸渍的凝胶材料。一种包括第一环形构件的装置，所述第一环形构件具有围绕所述第一环形构件的长度设置的第一腔和在所述第一环形构件的近端处的第一入口，以及联接到所述第一环形构件的第二环形构件，所述第二环形构件具有第二内腔设置在所述第二环形构件的大约一定长度处和在所述第二环形构件的近端处的第二入口，其中所述第一环形构件和所述第二环形构件被定位成允许通过每个环形构件引入的处理剂在治疗部位。

3. 发明授权

US08715265B2 Device and method for combining a treatment agent and a gel 失效
公开(公告)号：US08715265B2
公开(公告)日：2014-05-06
申请号：US13559438
申请日：2012-07-26
申请人： Charles D. Claude , Paul J. Kawula , Syed Faiyaz Ahmed Hossainy , Kimchi Tran
发明人： Charles D. Claude , Paul J. Kawula , Syed Faiyaz Ahmed Hossainy , Kimchi Tran
IPC分类号： A61M31/00
CPC分类号： A61K9/0024 , A61K9/06
摘要： A method including introducing a treatment agent at a treatment site within a mammalian host; and introducing a bioerodable gel material at the treatment site. An apparatus including a first annular member having a first lumen disposed about a length of the first annular member and a first entry port at a proximal end of the first annular member, and a second annular member coupled to the first annular member having a second lumen disposed about a length of the second annular member and a second entry port at a proximal end of the second annular member, wherein the first annular member and the second annular member are positioned to allow a combining of treatment agents introduced through each annular member at the treatment site.

4. 发明授权

US08870847B2 Blood vessel permeability-enhancement for the treatment of vascular diseases 有权
标题翻译：血管通透性增强用于治疗血管疾病
公开(公告)号：US08870847B2
公开(公告)日：2014-10-28
申请号：US13079239
申请日：2011-04-04
申请人： Dariush Davalian , Stephen Pacetti , Florian Niklas Ludwig , Syed Faiyaz Ahmed Hossainy , Irina Astafieva , Kimchi Tran
发明人： Dariush Davalian , Stephen Pacetti , Florian Niklas Ludwig , Syed Faiyaz Ahmed Hossainy , Irina Astafieva , Kimchi Tran
IPC分类号： A61M31/00 , A61L31/16 , A61L29/16 , A61M25/00 , A61M25/10 , A61F2/95
CPC分类号： A61K9/0019 , A61F2/95 , A61L29/16 , A61L31/16 , A61L2300/416 , A61L2300/62 , A61M25/0084 , A61M25/104 , A61M2025/105
摘要： This invention is directed to a method of treating a vascular disease involving administration to a patient by means of an angioplasty balloon a composition comprising a permeability-enhancing substance and a therapeutic agent.
摘要翻译：本发明涉及一种治疗血管疾病的方法，所述血管疾病涉及通过血管成形术球囊向患者施用包含渗透性增强物质和治疗剂的组合物。

5. 发明授权

US08500680B2 Device and method for combining a treatment agent and a gel 有权
标题翻译：用于组合处理剂和凝胶的装置和方法
公开(公告)号：US08500680B2
公开(公告)日：2013-08-06
申请号：US12013286
申请日：2008-01-11
申请人： Charles D. Claude , Paul J. Kawula , Syed Faiyaz Ahmed Hossainy , Kimchi Tran
发明人： Charles D. Claude , Paul J. Kawula , Syed Faiyaz Ahmed Hossainy , Kimchi Tran
IPC分类号： A61M37/00
CPC分类号： A61K9/0024 , A61K9/06
摘要： A method including introducing a treatment agent at a treatment site within a mammalian host; and introducing a bioerodable gel material at the treatment site. An apparatus including a first annular member having a first lumen disposed about a length of the first annular member and a first entry port at a proximal end of the first annular member, and a second annular member coupled to the first annular member having a second lumen disposed about a length of the second annular member and a second entry port at a proximal end of the second annular member, wherein the first annular member and the second annular member are positioned to allow a combining of treatment agents introduced through each annular member at the treatment site.
摘要翻译：一种方法，包括在哺乳动物宿主内的处理部位引入处理剂; 并在处理部位引入可生物浸渍的凝胶材料。一种包括第一环形构件的装置，所述第一环形构件具有围绕所述第一环形构件的长度设置的第一腔和在所述第一环形构件的近端处的第一入口，以及联接到所述第一环形构件的第二环形构件，所述第二环形构件具有第二内腔设置在所述第二环形构件的大约一定长度处和在所述第二环形构件的近端处的第二入口，其中所述第一环形构件和所述第二环形构件被定位成允许通过每个环形构件引入的处理剂在治疗部位。

6. 发明申请

US20120296312A1 DEVICE AND METHOD FOR COMBINING A TREATMENT AGENT AND A GEL 有权
标题翻译：用于组合治疗剂和凝胶的装置和方法
公开(公告)号：US20120296312A1
公开(公告)日：2012-11-22
申请号：US13559423
申请日：2012-07-26
申请人： Charles D. Claude , Paul J. Kawula , Syed Faiyaz Ahmed Hossainy , Kimchi Tran
发明人： Charles D. Claude , Paul J. Kawula , Syed Faiyaz Ahmed Hossainy , Kimchi Tran
IPC分类号： A61M5/00 , A61M25/00
CPC分类号： A61K9/0024 , A61K9/06
摘要： A method including introducing a treatment agent at a treatment site within a mammalian host; and introducing a bioerodable gel material at the treatment site. An apparatus including a first annular member having a first lumen disposed about a length of the first annular member and a first entry port at a proximal end of the first annular member, and a second annular member coupled to the first annular member having a second lumen disposed about a length of the second annular member and a second entry port at a proximal end of the second annular member, wherein the first annular member and the second annular member are positioned to allow a combining of treatment agents introduced through each annular member at the treatment site.
摘要翻译：一种方法，包括在哺乳动物宿主内的处理部位引入处理剂; 并在处理部位引入可生物浸渍的凝胶材料。一种包括第一环形构件的装置，所述第一环形构件具有围绕所述第一环形构件的长度设置的第一腔和在所述第一环形构件的近端处的第一入口，以及联接到所述第一环形构件的第二环形构件，所述第二环形构件具有第二内腔设置在所述第二环形构件的大约一定长度处和在所述第二环形构件的近端处的第二入口，其中所述第一环形构件和所述第二环形构件被定位成允许通过每个环形构件引入的处理剂在治疗部位。

7. 发明授权

US08637069B2 Device and method for combining a treatment agent and a gel 有权
标题翻译：用于组合处理剂和凝胶的装置和方法
公开(公告)号：US08637069B2
公开(公告)日：2014-01-28
申请号：US13559423
申请日：2012-07-26
申请人： Charles D. Claude , Paul J. Kawula , Syed Faiyaz Ahmed Hossainy , Kimchi Tran
发明人： Charles D. Claude , Paul J. Kawula , Syed Faiyaz Ahmed Hossainy , Kimchi Tran
IPC分类号： A61F13/00
CPC分类号： A61K9/0024 , A61K9/06
摘要： A method including introducing a treatment agent at a treatment site within a mammalian host; and introducing a bioerodable gel material at the treatment site. An apparatus including a first annular member having a first lumen disposed about a length of the first annular member and a first entry port at a proximal end of the first annular member, and a second annular member coupled to the first annular member having a second lumen disposed about a length of the second annular member and a second entry port at a proximal end of the second annular member, wherein the first annular member and the second annular member are positioned to allow a combining of treatment agents introduced through each annular member at the treatment site.
摘要翻译：一种方法，包括在哺乳动物宿主内的处理部位引入处理剂; 并在处理部位引入可生物浸渍的凝胶材料。一种包括第一环形构件的装置，所述第一环形构件具有围绕所述第一环形构件的长度设置的第一腔和在所述第一环形构件的近端处的第一入口，以及联接到所述第一环形构件的第二环形构件，所述第二环形构件具有第二内腔设置在所述第二环形构件的大约一定长度处和在所述第二环形构件的近端处的第二入口，其中所述第一环形构件和所述第二环形构件被定位成允许通过每个环形构件引入的处理剂在治疗部位。

8. 发明申请

US20110184384A1 Blood Vessel Permeability-Enhancement For The Treatment Of Vascular Diseases 有权
标题翻译：血管通透性增强用于治疗血管疾病
公开(公告)号：US20110184384A1
公开(公告)日：2011-07-28
申请号：US13079239
申请日：2011-04-04
申请人： Dariush Davalian , Stephen Pacetti , Florian Niklas Ludwig , Syed Faiyaz Ahmed Hossainy , Irina Astafieva , Kimchi Tran
发明人： Dariush Davalian , Stephen Pacetti , Florian Niklas Ludwig , Syed Faiyaz Ahmed Hossainy , Irina Astafieva , Kimchi Tran
IPC分类号： A61M25/00 , A61M25/10
CPC分类号： A61K9/0019 , A61F2/95 , A61L29/16 , A61L31/16 , A61L2300/416 , A61L2300/62 , A61M25/0084 , A61M25/104 , A61M2025/105
摘要： This invention relates to methods of enhancing the permeability of blood vessels to therapeutic agents.
摘要翻译：本发明涉及增强血管对治疗剂的渗透性的方法。

9. 发明授权

US07361368B2 Device and method for combining a treatment agent and a gel 有权
标题翻译：用于组合处理剂和凝胶的装置和方法
公开(公告)号：US07361368B2
公开(公告)日：2008-04-22
申请号：US10187007
申请日：2002-06-28
申请人： Charles D. Claude , Paul J. Kawula , Syed Faiyaz Ahmed Hossainy , Kimchi Tran
发明人： Charles D. Claude , Paul J. Kawula , Syed Faiyaz Ahmed Hossainy , Kimchi Tran
IPC分类号： A61F2/00 , A61K9/22
CPC分类号： A61K9/0024 , A61K9/06
摘要： A method including introducing a treatment agent at a treatment site within a mammalian host; and introducing a bioerodable gel material at the treatment site. An apparatus including a first annular member having a first lumen disposed about a length of the first annular member and a first entry port at a proximal end of the first annular member, and a second annular member coupled to the first annular member having a second lumen disposed about a length of the second annular member and a second entry port at a proximal end of the second annular member, wherein the first annular member and the second annular member are positioned to allow a combining of treatment agents introduced through each annular member at the treatment site.
摘要翻译：一种方法，包括在哺乳动物宿主内的处理部位引入处理剂; 并在处理部位引入可生物浸渍的凝胶材料。一种包括第一环形构件的装置，所述第一环形构件具有围绕所述第一环形构件的长度设置的第一腔和在所述第一环形构件的近端处的第一入口，以及联接到所述第一环形构件的第二环形构件，所述第二环形构件具有第二内腔设置在所述第二环形构件的大约一定长度处和在所述第二环形构件的近端处的第二入口，其中所述第一环形构件和所述第二环形构件被定位成允许通过每个环形构件引入的处理剂在治疗部位。

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