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1. 发明专利

IL273401D0 Novel anti-hla-a2 antibodies and uses thereof 未知
公开(公告)号：IL273401D0
公开(公告)日：2020-05-31
申请号：IL27340120
申请日：2020-03-18
申请人： UNIV BRITISH COLUMBIA , SANGAMO THERAPEUTICS FRANCE , LI ZHOU , TOBIAS ABEL , FRANCOIS MEYER , MEGAN LEVINGS , NICOLAS DAWSON , CAROLINE LAMARCHE
发明人： LI ZHOU , TOBIAS ABEL , FRANCOIS MEYER , MEGAN LEVINGS , NICOLAS DAWSON , CAROLINE LAMARCHE
IPC分类号： A61K35/17 , A61K39/00 , A61P37/06 , C07K14/705 , C07K14/725 , C07K16/28 , C12N15/62
摘要： The present invention relates to a novel anti-HLA-A2 antibody, and to a chimeric antigen receptor comprising said HLA-A2 antibody. The present invention further relates to an immune cell expressing said chimeric receptor antigen, and to therapeutic uses thereof, in particular for treating or preventing graft rejection or GVHD.

2. 发明公开

EP4134129A1 INTRACARDIAC ENERGY HARVESTING APPARATUS AND IMPLANTABLE ELECTRONIC MEDICAL DEVICE 审中-公开
公开(公告)号：EP4134129A1
公开(公告)日：2023-02-15
申请号：EP20930123.3
申请日：2020-05-26
申请人： Hua, Wei , LI, Zhou
发明人： LI, Zhou , HUA, Wei , LIU, Zhuo , HU, Yiran , OUYANG, Han
IPC分类号： A61N1/378 , A61N1/362
摘要： The present invention discloses an intracardiac energy harvesting device and an implantable electronic medical device, and belongs to the field of medical instruments. The intracardiac energy harvesting device includes a shell; a fixing mechanism arranged on the shell, and a fixing mechanism configured to fix the shell to an interior of a heart chamber to enable the shell to move along with beating of heart; wherein a nanogenerator module is packaged in the shell, which is configured to output electric energy in response to movement of the shell along with the heart beat; and a power management module is packaged in the shell for managing electric energy output by the nanogenerator module. According to the intracardiac energy collecting device disclosed by the present invention, the biological mechanical energy generated by heart beating can be collected in the heart through a minimally invasive interventional operation mode, surgical wounds are small, damage to the heart cannot be caused, and infection can be effectively avoided.

3. 发明申请

US20210228060A1 DISH WASHING MACHINE WITH HEAT EXCHANGERS 有权
公开(公告)号：US20210228060A1
公开(公告)日：2021-07-29
申请号：US17230571
申请日：2021-04-14
申请人： Kwok Din WONG , Li ZHOU
发明人： Kwok Din WONG , Li ZHOU
IPC分类号： A47L15/42 , A47L15/00 , F28D7/00
摘要： A dish washing machine including a housing having an interior wash space for washing dishes. The housing has a liquid inlet for adding a liquid to the dish washing machine. At least one rotating spray nozzle sprays the liquid onto dishes positioned within the interior wash space. The machine further includes a heating tank for heating the liquid which is supplied to the at least one rotating spray nozzle for spraying onto the dishes in the interior wash space. Two heat exchange systems are within the housing. The two heat exchange systems transfer heat from the liquid heated by the heating tank to the liquid added to the dish washing machine from the liquid inlet. A first one of the two heat exchange systems passes heat from water in the wash tank or the interior wash space to water in the first one of the two heat exchange systems.

4. 发明申请

US20190307307A1 DISH WASHING MACHINE WITH HEAT EXCHANGERS 审中-公开
公开(公告)号：US20190307307A1
公开(公告)日：2019-10-10
申请号：US15945279
申请日：2018-04-04
申请人： Kwok Din WONG , Li ZHOU
发明人： Kwok Din WONG , Li ZHOU
IPC分类号： A47L15/00 , A47L15/22 , A47L15/42
摘要： A dish washing machine including a housing having an interior wash space for washing dishes. The housing has a liquid inlet for adding a liquid to the dish washing machine. At least one spray nozzle sprays the liquid onto dishes positioned within the interior wash space. The machine further includes a heating tank for heating the liquid which is supplied to the at least one spray nozzle for spraying onto the dishes in the interior wash space. At least one heat exchange system is within the housing. The at least one heat exchange system transfers heat from the liquid heated by the heating tank to the liquid added to the dish washing machine from the liquid inlet.

5. 发明授权

US10390001B2 Rear view vision system for a vehicle 有权
公开(公告)号：US10390001B2
公开(公告)日：2019-08-20
申请号：US15634363
申请日：2017-06-27
申请人： He Li Zhou
发明人： He Li Zhou
IPC分类号： H04N13/00 , H04N13/02 , H04N13/04 , H04N7/18 , H04N13/243 , G06K9/00 , G02B27/14 , G02B27/01 , B60R1/00 , B60R1/04 , H04N13/156 , H04N13/344 , H04N5/445
摘要： A rear-view vision system for a vehicle is provided. The system includes a reflection device mounted adjacent a front windshield surface to redirect a reflection of a rear view of the vehicle. The system includes an image capturing device having a field of view facing the reflection device to capture a rear-view image of the reflection. The system may also include a display unit in communication with the image capturing device for displaying the captured rear-view image to a vehicle operator.

6. 发明授权

US08604351B2 Printed circuit board with circuit topology 失效
标题翻译：带电路拓扑的印刷电路板
公开(公告)号：US08604351B2
公开(公告)日：2013-12-10
申请号：US13335996
申请日：2011-12-23
申请人： Hua-Li Zhou , Chia-Nan Pai , Shou-Kuo Hsu
发明人： Hua-Li Zhou , Chia-Nan Pai , Shou-Kuo Hsu
IPC分类号： H05K1/09
CPC分类号： H05K1/0253
摘要： A printed circuit board includes a signal layer and a reference layer. The signal layer is covered with copper foil. A circuit topology for multiple loads is set on the signal layer. The circuit topology includes a driving terminal, a first signal receiving terminal, and a second signal receiving terminal. The driving terminal is connected to a node through a first transmission line. The node is connected to the first and second signal receiving terminals respectively through a second and a third transmission lines. A difference between lengths of the second and third transmission lines is greater than a product of a transmission speed and a rise time of signals from the driving terminal. The reference layer is covered with copper foil, and arranged under the signal layer. A region without copper foil is formed on the reference layer, under the second transmission line.
摘要翻译：印刷电路板包括信号层和参考层。信号层被铜箔覆盖。在信号层上设置多个负载的电路拓扑。电路拓扑包括驱动端子，第一信号接收端子和第二信号接收端子。驱动终端通过第一传输线连接到节点。节点分别通过第二和第三传输线连接到第一和第二信号接收终端。第二和第三传输线的长度之差大于来自驱动终端的信号的传输速度和上升时间的乘积。参考层用铜箔覆盖，并布置在信号层下面。在第二传输线下方，在参考层上形成没有铜箔的区域。

7. 发明申请

US20130074202A1 GENE SEQUENCES AND USES THEREOF IN PLANTS 审中-公开
公开(公告)号：US20130074202A1
公开(公告)日：2013-03-21
申请号：US13470467
申请日：2012-05-14
申请人： Thomas Adams , Ameeta K. Agarwa , Jeffrey Ahrens , James A. Ball , Amarjit Basra , Erin Bell , Terry L. Bradshaw , Paul S. Chomet , James H. Crowley , Jill Deikman , Molian Deng , Meghan Donnarummo , Kimberly Faye Zobrist Duff , Stephen Duff , Michael D. Edgerton , Banu Gopalan , Xiaoping He , Mackenzie Heal , Brendan S. Hinchey , Shihshieh Huang , Richard G. Johnson , Vincent Jung , Keith Kretzmer , Lucille B. Laccetti , Chao Qiang Lai , Garrett J. Lee , Michael H. Luethy , Timothy J. Leland , Jingdong Liu , Bin Lu , Adrian A. Lund , Linda L. Madson , Kathleen P. Malloy , Marcus Paul McNabnay , Manchikanti Padmavati , Thomas Ruff , William Start , Daniel Tennessen , Carl P. Urwin , Gabriela Vaduva , K. R. Vidya , Steven Thomas Voss , Christine Voyles , Zhango Xin , Nanfei Xu , Qingzhang Xu , Qiang Zhang , Yajuan Zhao , Li Zhou
发明人： Thomas Adams , Ameeta K. Agarwa , Jeffrey Ahrens , James A. Ball , Amarjit Basra , Erin Bell , Terry L. Bradshaw , Paul S. Chomet , James H. Crowley , Jill Deikman , Molian Deng , Meghan Donnarummo , Kimberly Faye Zobrist Duff , Stephen Duff , Michael D. Edgerton , Banu Gopalan , Xiaoping He , Mackenzie Heal , Brendan S. Hinchey , Shihshieh Huang , Richard G. Johnson , Vincent Jung , Keith Kretzmer , Lucille B. Laccetti , Chao Qiang Lai , Garrett J. Lee , Michael H. Luethy , Timothy J. Leland , Jingdong Liu , Bin Lu , Adrian A. Lund , Linda L. Madson , Kathleen P. Malloy , Marcus Paul McNabnay , Manchikanti Padmavati , Thomas Ruff , William Start , Daniel Tennessen , Carl P. Urwin , Gabriela Vaduva , K. R. Vidya , Steven Thomas Voss , Christine Voyles , Zhango Xin , Nanfei Xu , Qingzhang Xu , Qiang Zhang , Yajuan Zhao , Li Zhou
IPC分类号： C12N15/82 , A01D45/00
CPC分类号： C12N15/8279 , A01D45/00 , A01N25/34 , A01N31/16 , A01N41/10 , A01N43/40 , A01N43/653 , A01N43/78 , A01N43/80 , A01N55/02 , C07K14/415 , C12N9/0071 , C12N15/8241 , C12N15/8243 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12N15/8273 , C12N15/8274 , C12N15/8275 , C12Y114/12017 , A01N25/10 , A01N25/02 , A01N2300/00
摘要： This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.

8. 发明申请

US20130049461A1 CIRCUIT TOPOLOGY OF PRINTED CIRCUIT BOARD 审中-公开
标题翻译：印刷电路板电路拓扑
公开(公告)号：US20130049461A1
公开(公告)日：2013-02-28
申请号：US13336000
申请日：2011-12-23
申请人： SHI-PIAO LUO , HUA-LI ZHOU , CHIA-NAN PAI , SHOU-KUO HSU
发明人： SHI-PIAO LUO , HUA-LI ZHOU , CHIA-NAN PAI , SHOU-KUO HSU
IPC分类号： H02J4/00
CPC分类号： H05K1/0248 , H03K5/1534 , H03K19/00346 , H04L25/0278 , H05K1/0231 , H05K1/0246 , H05K2201/10015 , Y10T307/25
摘要： A circuit topology for multiple loads includes a driving terminal, first and second signal receiving terminals, and a capacitor. The driving terminal is connected to a node through a first transmission line. The node is connected to the first and second signal receiving terminals through second and third transmission lines. The second transmission line is longer than the third transmission line, and a difference between lengths of the second and third transmission lines is greater than a product of a transmission speed and a rise time of signals from the driving terminal. A first terminal of the capacitor is connected to the third transmission line. A second terminal of the capacitor is grounded. A distance between the capacitor and the second signal receiving terminal is less than a distance between the capacitor and the node.
摘要翻译：用于多个负载的电路拓扑包括驱动端子，第一和第二信号接收端子以及电容器。驱动终端通过第一传输线连接到节点。节点通过第二和第三传输线连接到第一和第二信号接收终端。第二传输线比第三传输线长，并且第二传输线和第三传输线的长度之间的差大于来自驱动终端的信号的传输速度和上升时间的乘积。电容器的第一端子连接到第三传输线。电容器的第二个端子接地。电容器和第二信号接收端子之间的距离小于电容器和节点之间的距离。

9. 发明申请

US20120244583A1 Method for Preparing High Purity L-alpha Glycerylphosphorylcholine 有权
标题翻译：高纯度L-α甘油磷酰胆碱的制备方法
公开(公告)号：US20120244583A1
公开(公告)日：2012-09-27
申请号：US13071126
申请日：2011-03-24
申请人： Yuanfa Liu , Kangyi Zhang , Xingguo Wang , Xiangyun Qian , Li Zhou , Zhihua Song
发明人： Yuanfa Liu , Kangyi Zhang , Xingguo Wang , Xiangyun Qian , Li Zhou , Zhihua Song
IPC分类号： C12P13/00
CPC分类号： C12P9/00 , C12P13/001
摘要： Disclosed is a method for preparing L-α-Glycerylphosphorylcholine with high yields and purity. The method uses phospholipase A1-based enzymatic hydrolysis, ion-exchange resin purification and silica gel column chromatography to prepare L-α-glycerylphosphorylcholin with purity up to 99.8% and a final yield up to 78.4%. The method disclosed is simple, cost-effective, environmentally friendly, and adaptable to industrial applications.
摘要翻译：公开了以高产率和纯度制备L-α-甘油基磷酰胆碱的方法。该方法采用磷脂酶A1酶水解，离子交换树脂纯化和硅胶柱色谱法制备纯度高达99.8％的L-α-甘油基磷酰胆碱，最终产率高达78.4％。所公开的方法简单，成本效益高，环保，适用于工业应用。

10. 发明申请

US20120007688A1 PRINTED CIRCUIT BOARD 有权
标题翻译：印刷电路板
公开(公告)号：US20120007688A1
公开(公告)日：2012-01-12
申请号：US12960321
申请日：2010-12-03
申请人： HUA-LI ZHOU , MING WEI , CHIA-NAN PAI , SHOU-KUO HSU
发明人： HUA-LI ZHOU , MING WEI , CHIA-NAN PAI , SHOU-KUO HSU
IPC分类号： H01P3/08
CPC分类号： H05K1/0245 , H05K2201/09727
摘要： A printed circuit board includes an insulation layer and a signal layer attached to the insulation layer. The signal layer includes a pair of differential transmission lines. Width W of each of the differential transmission lines is changed according to change of space S between the differential transmission lines, based on the following formula: W = C   1 × H × ( C   2 × H 0.8  W 0 + T ) C   3 ×  C   4 × S 0 H - 1 1 - C   3 ×  C   4 × S H - 1.25  T In above formula, C1=7.475, C2=5.98, C3=0.48, C4=−0.96, H is a thickness of the insulation layer, W0 is an original width of each of the differential transmission lines, and S0 is an original space between the differential transmission lines, and T is a thickness of each of the differential transmission lines.
摘要翻译：印刷电路板包括绝缘层和附着到绝缘层的信号层。信号层包括一对差动传输线。差分传输线的宽度W根据以下公式根据差分传输线之间的空间S的变化而改变：W = C 1 / H×（C 2 2×H 0.8 W 0 + 在上式中，C 1 = 7.475，C 2 = 5.98，C 3 = C 9，C 3 = 0.48，C4 = -0.96，H是绝缘层的厚度，W0是差分传输线的原始宽度，S0是差动传输线之间的原始空间，T是各个差分传输线的厚度差动传输线。

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