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    • 1. 发明授权
    • Process for preparing blown vegetable oil
    • 吹制植物油的制备方法
    • US07262311B2
    • 2007-08-28
    • US10835367
    • 2004-04-29
    • Rodney ChristiansonMichael NobleAndrew RourkeEric GeigerLarry Mahlum
    • Rodney ChristiansonMichael NobleAndrew RourkeEric GeigerLarry Mahlum
    • C11B7/00C11B3/00
    • C11B3/00A23D9/00C11B3/16
    • A method for partially refining a crude vegetable oil utilizing physical refining techniques is described. The crude vegetable oil is first degummed by either (1) allowing the crude oil to settle over a period of time, such as twenty days, so that the oil becomes stratified into at least two layers, wherein one layer comprises gums with low oil content and a second layer comprises oil containing only a fraction of the gums originally present and then separating the oil layer from the gum layer, or (2) heating the crude oil to a temperature of about 270-300° F. with agitation and then allowing the crude oil to settle for a period of time until the oil becomes stratified into the at least two layers. The degummed oil is then aerated and agitated while being maintained at a temperature of 170-180° F. for a time period sufficient to obtain a desired oil viscosity. The resulting partially refined oil is suitable for use in industrial applications such as the preparation of urethane foams.
    • 描述了利用物理精制技术部分精炼粗植物油的方法。 首先使原油植物油脱胶,(1)允许原油在一段时间如二十天内沉降,使得油分层成至少两层,其中一层包含油含量低的树胶 并且第二层包含仅含有原始存在的一部分树胶的油,然后将油层与胶层分离,或(2)在搅拌下将原油加热至约270-300°F的温度,然后允许 原油沉淀一段时间,直到油分层成至少两层。 然后将脱胶油充气并搅拌,同时保持在170-180°F的温度下足够长的时间以获得所需的油粘度。 所得到的部分精制油适用于工业应用,例如制备聚氨酯泡沫。
    • 2. 发明申请
    • Process for preparing blown vegetable oil
    • 吹制植物油的制备方法
    • US20050065356A1
    • 2005-03-24
    • US10835367
    • 2004-04-29
    • Rodney ChristiansonMichael NobleAndrew RourkeEric GeigerLarry Mahlum
    • Rodney ChristiansonMichael NobleAndrew RourkeEric GeigerLarry Mahlum
    • A23D9/00C11B3/00C11B3/16C07C51/43
    • C11B3/00A23D9/00C11B3/16
    • A method for partially refining a crude vegetable oil utilizing physical refining techniques is described. The crude vegetable oil is first degummed by either (1) allowing the crude oil to settle over a period of time, such as twenty days, so that the oil becomes stratified into at least two layers, wherein one layer comprises gums with low oil content and a second layer comprises oil containing only a fraction of the gums originally present and then separating the oil layer from the gum layer, or (2) heating the crude oil to a temperature of about 270-300° F. with agitation and then allowing the crude oil to settle for a period of time until the oil becomes stratified into the at least two layers. The degummed oil is then aerated and agitated while being maintained at a temperature of 170-180° F. for a time period sufficient to obtain a desired oil viscosity. The resulting partially refined oil is suitable for use in industrial applications such as the preparation of urethane foams.
    • 描述了利用物理精制技术部分精炼粗植物油的方法。 首先使原油植物油脱胶,(1)允许原油在一段时间如二十天内沉降,使得油分层成至少两层,其中一层包含油含量低的树胶 并且第二层包含仅含有原始存在的一部分树胶的油,然后将油层与胶层分离,或(2)在搅拌下将原油加热至约270-300°F的温度,然后允许 原油沉淀一段时间,直到油分层成至少两层。 然后将脱胶油充气并搅拌,同时保持在170-180°F的温度下足够长的时间以获得所需的油粘度。 所得到的部分精制油适用于工业应用,例如制备聚氨酯泡沫。
    • 3. 发明申请
    • DEVICES AND METHODS FOR TESTING ANALYTES
    • 用于测试分析仪的设备和方法
    • US20130112573A1
    • 2013-05-09
    • US13696380
    • 2011-05-06
    • Michael NobleCraig NelsonMark HumphriesCarys LloydDavid EdingtonJohn Rippeth
    • Michael NobleCraig NelsonMark HumphriesCarys LloydDavid EdingtonJohn Rippeth
    • C12Q1/00
    • G01N27/3272C12Q1/006C12Q1/54G01N27/3274G01N33/4915G01N2496/00
    • A method and device are provided for measuring a level of a clinically relevant analyte (such as glucose) in a fluid (such as blood). The device includes a flow path for conducting said fluid through the device; a detection chamber arranged on said flow path; and detector means arranged to detect analyte levels in the fluid in said chamber, wherein: said detection chamber contains a predetermined amount of an analyte such that that analyte mixes with fluid in the detection chamber to form, at the detector means, a calibration sample of the fluid at a time after the arrival of the fluid in said detection chamber, and said detector means is arranged to detect a first analyte level of an unadulterated sample of the fluid at a first time which is before the formation of said calibration sample and to detect a second analyte level of said calibration sample at a second time which is after the formation of said calibration sample.
    • 提供了一种用于测量流体(例如血液)中的临床相关分析物(例如葡萄糖)的水平的方法和装置。 该装置包括用于通过该装置传导所述流体的流路; 布置在所述流路上的检测室; 以及检测器装置,其布置成检测所述室中的流体中的分析物水平,其中:所述检测室包含预定量的分析物,使得分析物与检测室中的流体混合,以在检测器装置处形成校准样品 在流体到达所述检测室之后的时间处的流体和所述检测器装置被布置成在形成所述校准样品之前的第一时间检测流体的未掺杂样品的第一分析物水平,并且 在形成所述校准样品之后的第二时间检测所述校准样品的第二分析物水平。
    • 4. 发明授权
    • Devices and methods for measuring clinically relevant analytes in fluids
    • 用于测量流体中临床相关分析物的装置和方法
    • US07548773B2
    • 2009-06-16
    • US10589532
    • 2005-02-16
    • Michael Noble
    • Michael Noble
    • A61B5/05A61B5/157
    • G01N27/3274
    • Methods and devices for the measurement of clinically relevant analytes in fluids are provided. The devices and methods are particularly relevant for detection of glucose in blood and allow internal calibration of measurements. One device includes a flow path for conducting the fluid through the device; a predetermined amount of the analyte arranged on the flow path such that the analyte mixes with fluid that passes it to form a calibration sample of the fluid and detector means arranged on the flow path for detecting respective analyte levels in an unadulterated sample of the fluid and in the calibration sample. Another device provides a predetermined amount of a calibration analyte of a different species to the clinically relevant analyte arranged on the flow path, and first and second detector means for detecting the levels of the clinically relevant analyte and the calibration analyte.
    • 提供了用于测量流体中临床相关分析物的方法和装置。 这些装置和方法对于检测血液中的葡萄糖和测量的内部校准特别重要。 一个装置包括用于使流体穿过装置的流路; 预定量的分析物布置在流动路径上,使得分析物与通过其的流体混合以形成流体的校准样品和布置在流动路径上的检测器装置,用于检测流体的未掺杂样品中的相应分析物水平, 在校准样品中。 另一个装置向布置在流动路径上的临床相关分析物提供预定量的不同物种的校准分析物,以及用于检测临床相关分析物和校准分析物的水平的第一和第二检测器装置。
    • 7. 发明申请
    • AN INSERTER
    • 插入器
    • US20110172593A1
    • 2011-07-14
    • US13119399
    • 2009-09-11
    • Heikki LyyikäinenIikka JutilaCalvo AlonsonHarri JukarainenTaina TjäderAndrew MacleodMichael NobleDavid Whitaker
    • Heikki LyyikäinenIikka JutilaCalvo AlonsonHarri JukarainenTaina TjäderAndrew MacleodMichael NobleDavid Whitaker
    • A61M31/00
    • A61F6/18A61F6/142
    • The present invention relates to an inserter for an intrauterine system, comprising a handle (3) having a longitudinal opening (8) at its first end, said opening (8) having a longitudinal axis parallel to the longitudinal axis of the inserter, a first end (8a) and a second end (8b), a movable slider (5) arranged in said longitudinal opening (8) and having a first end (5a) and a second end (5b), a plunger (2) attached to the handle (3) and having a longitudinal axis, and an insertion tube (6) having a first end, a second end and a longitudinal axis essentially parallel to the longitudinal axis of the plunger (2), the insertion tube (6) being, along said longitudinal axis, movably arranged around the plunger (2). The invention is characterised in that it further comprises a flange (4) arranged on the insertion tube (6) at its first end, and means for locking the slider (5) into a position showing the correct insertion depth for the intrauterine system, said means being adjustable with respect to the opening (8) of the handle.
    • 本发明涉及一种用于子宫内系统的插入器,包括在其第一端具有纵向开口(8)的手柄(3),所述开口(8)具有平行于插入器的纵向轴线的纵向轴线,第一 端部(8a)和第二端(8b),布置在所述纵向开口(8)中并具有第一端(5a)和第二端(5b)的可动滑块(5) 手柄(3)并且具有纵向轴线,以及插入管(6),其具有基本上平行于柱塞(2)的纵向轴线的第一端,第二端和纵向轴线, 沿着所述纵向轴线可移动地布置在所述柱塞(2)周围。 本发明的特征在于它还包括在其第一端处布置在插入管(6)上的凸缘(4),以及用于将滑块(5)锁定到显示宫内系统的正确插入深度的位置的装置,所述 相对于手柄的开口(8)可调节的装置。
    • 10. 发明申请
    • Devices And Methods For Measuring Clinically Relevant Analytes In Fluids
    • 用于测量液体中临床相关分析物的装置和方法
    • US20070202606A1
    • 2007-08-30
    • US10589532
    • 2005-02-16
    • Michael Noble
    • Michael Noble
    • G01N21/00
    • G01N27/3274
    • Methods and devices for the measurement of clinically relevant analytes in fluids are provided. The devices and methods are particularly relevant for detection of glucose in blood and allow internal calibration of measurements. One device includes a flow path for conducting the fluid through the device; a predetermined amount of the analyte arranged on the flow path such that the analyte mixes with fluid that passes it to form a calibration sample of the fluid and detector means arranged on the flow path for detecting respective analyte levels in an unadulterated sample of the fluid and in the calibration sample. Another device provides a predetermined amount of a calibration analyte of a different species to the clinically relevant analyte arranged on the flow path, and first and second detector means for detecting the levels of the clinically relevant analyte and the calibration analyte. One method includes the steps of mixing a sample of the fluid with a known amount of the analyte to form a calibration sample, measuring the analyte levels in both the calibration sample and the unadulterated sample and adjusting the level measured in the unadulterated sample using the level measured in the calibration sample. Another method mixes a known amount of a calibration analyte of a different species to the clinically relevant analyte with the fluid; measures the levels of the clinically relevant analyte and the calibration analyte and adjusts the measured level of the clinically relevant analyte accordingly.
    • 提供了用于测量流体中临床相关分析物的方法和装置。 这些装置和方法对于检测血液中的葡萄糖和测量的内部校准特别重要。 一个装置包括用于使流体穿过装置的流路; 预定量的分析物布置在流动路径上,使得分析物与通过其的流体混合以形成流体的校准样品和布置在流动路径上的检测器装置,用于检测流体的未掺杂样品中的相应分析物水平, 在校准样品中。 另一个装置向布置在流动路径上的临床相关分析物提供预定量的不同物种的校准分析物,以及用于检测临床相关分析物和校准分析物的水平的第一和第二检测器装置。 一种方法包括以下步骤:将流体样品与已知量的分析物混合以形成校准样品,测量校准样品和未掺杂样品中的分析物水平,并使用水平调节在未掺杂样品中测量的水平 在校准样品中测量。 另一种方法将已知量的不同物种的校准分析物与临床相关的分析物与流体混合; 测量临床相关分析物和校准分析物的水平,并相应调整临床相关分析物的测量水平。