专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09375349B2 System and method for providing laser shot patterns to the lens of an eye 有权
标题翻译：用于向眼睛的镜片提供激光射击图案的系统和方法
公开(公告)号：US09375349B2
公开(公告)日：2016-06-28
申请号：US12842870
申请日：2010-07-23
申请人： Rudolph W. Frey , Steven E. Bott , Gary P. Gray
发明人： Rudolph W. Frey , Steven E. Bott , Gary P. Gray
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00825 , A61F9/00838 , A61F2009/0087 , A61F2009/00897
摘要： There is provided a system, apparatus and methods for developing laser systems that can create precise predetermined shot patterns for providing areas of varying softness in the lens of an eye. These areas of varying softness may have shapes that correspond to instruments used to remove material from the lens of the eye. There is further provided a multiplicity of spheres pattern, which may provide for bubble formation which in turn lubricates the lens material for removal after sectioning.
摘要翻译：提供了一种用于开发激光系统的系统，装置和方法，其可以创建精确的预定射击模式，以在眼睛的晶状体中提供变化的柔软度的区域。这些变化柔软的区域可以具有与用于从眼睛的镜片中去除材料的仪器相对应的形状。还提供了多种球形图案，其可以提供气泡形成，其又在切片之后润滑透镜材料以便去除。

2. 发明授权

US08556425B2 Purkinjie image-based alignment of suction ring in ophthalmic applications 有权
标题翻译： Purkinjie基于图像的吸引环在眼科应用中的对准
公开(公告)号：US08556425B2
公开(公告)日：2013-10-15
申请号：US13017702
申请日：2011-01-31
申请人： Rudolph W. Frey , Steven E. Bott
发明人： Rudolph W. Frey , Steven E. Bott
IPC分类号： A61B3/14 , A61B3/00 , A61B18/18
CPC分类号： A61F9/009 , A61F9/00825 , A61F2009/0087 , A61F2009/00872 , A61F2009/00889
摘要： An alignment device including means for releasably attaching a suction ring and means for applying a pattern of light to an eye of a patient. The alignment device further including means for detecting light reflected from the eye and determining whether the suction ring is aligned relative to the eye based on the detected light.
摘要翻译：一种对准装置，包括用于可释放地附接吸入环的装置和用于向患者的眼睛施加光图案的装置。对准装置还包括用于检测从眼睛反射的光并基于检测到的光来确定吸入环是否相对于眼睛对准的装置。

3. 发明申请

US20120330290A1 SYSTEM AND METHOD FOR MEASURING TILT IN THE CRYSTALLINE LENS FOR LASER PHACO FRAGMENTATION 审中-公开
标题翻译：用于激光激光碎片的晶体镜片中的倾斜测量系统和方法
公开(公告)号：US20120330290A1
公开(公告)日：2012-12-27
申请号：US13427319
申请日：2012-03-22
申请人： Gary P. Gray , Rudolph W. Frey , Steven E. Bott
发明人： Gary P. Gray , Rudolph W. Frey , Steven E. Bott
IPC分类号： A61B18/20 , G06K9/78
CPC分类号： A61B3/145 , A61B3/10 , A61F9/008 , A61F2009/0087 , A61F2009/00872 , A61F2009/00878 , A61F2009/00889 , H04N19/523
摘要： A method of generating three dimensional shapes for a cornea and lens, the method including illuminating an eye with multiple sections of light and obtaining multiple sectional images of the eye based on the multiple sections of light. For each obtained multiple sectional image, the following processes are performed: a) automatically identifying arcs corresponding to anterior and posterior corneal and lens surfaces of the eye by image analysis and curve fitting of the obtained multiple sectional images; and b) determining an intersection of lines ray traced back from the identified arcs with a known position of a section of space containing the section of light that generated the obtained multiple sectional images, wherein the intersection defines a three-dimensional arc curve. The method further including reconstructing three-dimensional shapes of the cornea surfaces and the lens surfaces based on fitting the three-dimensional arc curve to a three-dimensional shape.
摘要翻译：一种用于产生角膜和晶状体的三维形状的方法，所述方法包括以多个部分的光照射眼睛，并且基于所述多个部分的光线获得所述眼睛的多个截面图像。对于每个获得的多个截面图像，执行以下处理：a）通过所获得的多个截面图像的图像分析和曲线拟合来自动识别与眼睛的前角膜和后角膜和眼镜面相对应的弧; 以及b）确定从所识别的弧线回溯的线光线与包含产生所获得的多个截面图像的光的部分的空间部分的已知位置的交点，其中所述交点限定三维弧形曲线。该方法还包括基于将三维弧曲线拟合为三维形状来重建角膜表面和透镜表面的三维形状。

4. 发明申请

US20110190740A1 PLACIDO RING MEASUREMENT OF ASTIGMATISM AXIS AND LASER MARKING OF ASTIGMATISM AXIS 审中-公开
标题翻译：惯性轴的定位环测量和轴向的激光标记
公开(公告)号：US20110190740A1
公开(公告)日：2011-08-04
申请号：US13017499
申请日：2011-01-31
申请人： Rudolph W. Frey , Steven E. Bott
发明人： Rudolph W. Frey , Steven E. Bott
IPC分类号： A61B18/20 , A61B3/107
CPC分类号： A61F9/00825 , A61F9/00827 , A61F2009/0087 , A61F2009/00872 , A61F2009/00889
摘要： A laser treatment system that includes means for measuring an astigmatism axis of a cornea of an eye of a patient and means for applying a laser beam to the eye.
摘要翻译：一种激光治疗系统，其包括用于测量患者眼睛的角膜的散光轴线的装置和将激光束施加到眼睛的装置。

5. 发明申请

US20100022994A1 LIQUID FILLED INDEX MATCHING DEVICE FOR OPHTHALMIC LASER PROCEDURES 有权
标题翻译：液体填充指示器用于光学激光程序
公开(公告)号：US20100022994A1
公开(公告)日：2010-01-28
申请号：US12509021
申请日：2009-07-24
申请人： Rudolph W. Frey , Steven E. Bott , Gerrit N. Porter
发明人： Rudolph W. Frey , Steven E. Bott , Gerrit N. Porter
IPC分类号： A61F9/009
CPC分类号： A61F9/009 , A61F2009/0087 , A61F2009/00889
摘要： There is provided a device for use as an interface between a laser surgery device and the eye of a patient. The device is filled with a liquid that matches the index of refraction of the eye. The device further has a curved lens that follows the curvature of the outer surface of the patient's eye. In this manner the interface device, through which the laser beam must travel, has essentially the same index of refraction as the eye.
摘要翻译：提供了用作激光手术装置和患者眼睛之间的界面的装置。该装置充满与眼睛的折射率匹配的液体。该装置还具有跟随患者眼睛的外表面的曲率的弯曲透镜。以这种方式，激光束必须行进的界面装置具有与眼睛基本上相同的折射率。

6. 发明授权

US5698411A Method for determining activity of enzymes in metabolically active whole cells 失效
标题翻译：测定代谢活性全细胞中酶活性的方法
公开(公告)号：US5698411A
公开(公告)日：1997-12-16
申请号：US444051
申请日：1995-05-18
申请人： Frank J. Lucas , Gerald E. Jaffe , Steven E. Bott , James H. Carter
发明人： Frank J. Lucas , Gerald E. Jaffe , Steven E. Bott , James H. Carter
IPC分类号： C12Q1/26 , C12Q1/34 , C12Q1/37 , G01N33/574 , G01N33/58 , C12Q1/02 , C12Q1/00
CPC分类号： G01N33/574 , C12Q1/26 , C12Q1/34 , C12Q1/37 , G01N33/582 , G01N2333/95 , G01N2333/96413 , G01N2333/96466 , G01N2333/96469 , G01N2800/52
摘要： A method for assaying the activity of an enzyme inside a metabolically active whole cell is disclosed. The assay compound includes a leaving group and an indicator group. The leaving group is selected from the group comprising amino acids, peptides, saccharides, sulfates, phosphates, esters, phosphate esters, nucleotides, polynucleotides, nucleic acids, pyrimidines, purines, nucleosides, lipids and mixtures thereof. The indicator group is selected from compounds which have a first state when joined to the leaving group, and a second state when the leaving group is cleaved from the indicator group by the enzyme. Preferably, the indicator compounds are rhodamine 110, rhodol, and fluorescein and analogs of these compounds. A method of synthesizing the compound is also disclosed.
摘要翻译：公开了一种用于测定代谢活性全细胞内酶的活性的方法。测定化合物包括离去基团和指示剂组。离去基团选自包括氨基酸，肽，糖，硫酸盐，磷酸盐，酯，磷酸酯，核苷酸，多核苷酸，核酸，嘧啶，嘌呤，核苷，脂质及其混合物的组。指示基团选自与离去基团连接时具有第一状态的化合物，当离去基团被酶从指示剂基团切割时的第二种状态。优选地，指示剂化合物是这些化合物的罗丹明110，rhodol和荧光素以及类似物。还公开了合成该化合物的方法。

7. 发明授权

US11185226B2 System and method for measuring tilt in the crystalline lens for laser phaco fragmentation 有权
公开(公告)号：US11185226B2
公开(公告)日：2021-11-30
申请号：US13427319
申请日：2012-03-22
申请人： Gary P. Gray , Rudolph W. Frey , Steven E. Bott
发明人： Gary P. Gray , Rudolph W. Frey , Steven E. Bott
IPC分类号： A61B18/20 , G06K9/78 , A61B3/14 , A61F9/008 , A61B3/10 , H04N19/523
摘要： A method of generating three dimensional shapes for a cornea and lens, the method including illuminating an eye with multiple sections of light and obtaining multiple sectional images of the eye based on the multiple sections of light. For each obtained multiple sectional image, the following processes are performed: a) automatically identifying arcs corresponding to anterior and posterior corneal and lens surfaces of the eye by image analysis and curve fitting of the obtained multiple sectional images; and b) determining an intersection of lines ray traced back from the identified arcs with a known position of a section of space containing the section of light that generated the obtained multiple sectional images, wherein the intersection defines a three-dimensional arc curve. The method further including reconstructing three-dimensional shapes of the cornea surfaces and the lens surfaces based on fitting the three-dimensional arc curve to a three-dimensional shape.

8. 发明授权

US10463541B2 System and method for correcting astigmatism using multiple paired arcuate laser generated corneal incisions 有权
公开(公告)号：US10463541B2
公开(公告)日：2019-11-05
申请号：US13427149
申请日：2012-03-22
申请人： Rudolph W. Frey , Eric Valas Teuma , Steven E. Bott
发明人： Rudolph W. Frey , Eric Valas Teuma , Steven E. Bott
IPC分类号： A61F9/008
摘要： A method for the reduction or elimination of astigmatism in an eye that includes an astigmatism axis, the method including determining an astigmatism axis of an eye and forming a first set of incisions in a cornea of the eye that are bisected by the astigmatism axis. The method including forming a second set of incisions in the cornea that are bisected by the astigmatism axis, wherein the first set of incisions and the second set of incisions reduce or eliminate astigmatism in the eye.

9. 发明申请

US20170014027A9 SYSTEM AND METHOD FOR MEASURING TILT IN THE CRYSTALLINE LENS FOR LASER PHACO FRAGMENTATION 审中-公开
标题翻译：用于激光激光碎片的晶体镜片中的倾斜测量系统和方法
公开(公告)号：US20170014027A9
公开(公告)日：2017-01-19
申请号：US13427319
申请日：2012-03-22
申请人： Gary P. Gray , Rudolph W. Frey , Steven E. Bott
发明人： Gary P. Gray , Rudolph W. Frey , Steven E. Bott
IPC分类号： A61B18/20 , G06K9/78
CPC分类号： A61B3/145 , A61B3/10 , A61F9/008 , A61F2009/0087 , A61F2009/00872 , A61F2009/00878 , A61F2009/00889 , H04N19/523
摘要： A method of generating three dimensional shapes for a cornea and lens, the method including illuminating an eye with multiple sections of light and obtaining multiple sectional images of the eye based on the multiple sections of light. For each obtained multiple sectional image, the following processes are performed: a) automatically identifying arcs corresponding to anterior and posterior corneal and lens surfaces of the eye by image analysis and curve fitting of the obtained multiple sectional images; and b) determining an intersection of lines ray traced back from the identified arcs with a known position of a section of space containing the section of light that generated the obtained multiple sectional images, wherein the intersection defines a three-dimensional arc curve. The method further including reconstructing three-dimensional shapes of the cornea surfaces and the lens surfaces based on fitting the three-dimensional arc curve to a three-dimensional shape.
摘要翻译：一种用于产生角膜和晶状体的三维形状的方法，所述方法包括以多个部分的光照射眼睛，并且基于所述多个部分的光线获得所述眼睛的多个截面图像。对于每个获得的多个截面图像，执行以下处理：a）通过所获得的多个截面图像的图像分析和曲线拟合来自动识别与眼睛的前角膜和后角膜和眼镜面相对应的弧; 以及b）确定从所识别的弧线回溯的线光线与包含产生所获得的多个截面图像的光的部分的空间部分的已知位置的交点，其中所述交点限定三维弧形曲线。该方法还包括基于将三维弧曲线拟合为三维形状来重建角膜表面和透镜表面的三维形状。

10. 外观设计

USD695408S1 Laser system for treatment of the eye 有权
标题翻译：用于治疗眼睛的激光系统
公开(公告)号：USD695408S1
公开(公告)日：2013-12-10
申请号：US29377018
申请日：2010-10-15
申请人： Steven E. Bott , Rudolph W. Frey , Gerrit N. Porter , Scott Howard Wakefield , William D. Chura
设计人： Steven E. Bott , Rudolph W. Frey , Gerrit N. Porter , Scott Howard Wakefield , William D. Chura

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式