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    • 4. 发明授权
    • Functional food containing sodium tricaffeoylaldarate
    • 功能性食品含有三角酰基乳酸钠
    • US08372890B2
    • 2013-02-12
    • US12304803
    • 2007-06-18
    • Sumio TeradaKikuo ItohNaoto NoguchiTakashi Ishida
    • Sumio TeradaKikuo ItohNaoto NoguchiTakashi Ishida
    • A61K31/045A61K36/00
    • A61K36/00A61K31/216
    • Components that demonstrate an α-glucosidase inhibitory activity and hyperglycemic inhibitory activity have clearly been provided from among the components included in Yacon. The present inventors found that as a result of screening for a strong anti-oxidant component in a Yacon aerial portion extract, an antioxidant activity was converged in a DIAION HP-20 column chromatography 50% methanol-eluted fraction of hot water extract. Thus, since a previously unidentified high-content component was confirmed, the present inventors conducted purification thereof, and thereby separated TCAA. As a result, this TCAA was found to be the component that demonstrates the α-glucosidase inhibitory activity and hyperglycemic inhibitory activity.
    • 从Yacon中包含的成分中可以清楚地提供表现出α-葡萄糖苷酶抑制活性和高血糖抑制活性的成分。 本发明人发现,通过在Yacon天线部分提取物中筛选强抗氧化成分的结果,将抗氧化活性会聚在DIAION HP-20柱色谱法50%甲醇洗脱的热水提取物部分中。 因此,由于确认了先前未鉴定的高含量成分,本发明人进行了纯化,从而分离出TCAA。 结果发现该TCAA是显示α-葡糖苷酶抑制活性和高血糖抑制活性的成分。