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1. 发明专利

BR1100908A 未知
公开(公告)号：BR1100908A
公开(公告)日：1999-08-31
申请号：BR1100908
申请日：1997-05-14
申请人： MOHAMMED SHOYAB , JOYCE M. ZARLING , HANS MARQUARDT , MARCIA B. HANSON , THOMAS J. BROWN
发明人： SHOYAB MOHAMMED , ZARLING JOYCE M , MARQUARDT HANS , HANSON MARCIA B , BROWN THOMAS J
IPC分类号： A61B20060101 , A61K20060101 , A61K38/16 , A61K38/21 , A61K39/395 , C07K20060101 , C07K14/00 , C07K14/555 , C12N20060101 , C12N15/00 , C12P19/34 , C12Q20060101 , G01N33/68

2. 发明申请

US20110006921A1 ANTI-THEFT, EMERGENCY SYSTEM 有权
标题翻译：防盗，紧急系统
公开(公告)号：US20110006921A1
公开(公告)日：2011-01-13
申请号：US12499481
申请日：2009-07-08
申请人： Thomas J. BROWN
发明人： Thomas J. BROWN
IPC分类号： G08B23/00
CPC分类号： B63J99/00 , B63B2017/0009
摘要： Disclosed is an antitheft, emergency system for a vehicle. The system may include a system activation switch, at least one emergency switch, an engine shutoff element connected to the engine, and an emergency transmitter. The at least one emergency switch may trigger the engine shutoff element to render the engine inoperational and may simultaneously, covertly trigger an emergency transmitter to transmit a distress signal.
摘要翻译：公开了一种用于车辆的防盗，应急系统。系统可以包括系统激活开关，至少一个紧急开关，连接到发动机的发动机关闭元件和紧急发射器。所述至少一个紧急开关可以触发所述发动机关闭元件以使所述发动机不工作，并且可以同时隐蔽地触发紧急发射器发送遇险信号。

3. 发明授权

US5958442A Oncostatin M for treating inflammation 失效
标题翻译：制瘤素M用于治疗炎症
公开(公告)号：US5958442A
公开(公告)日：1999-09-28
申请号：US957234
申请日：1997-10-24
申请人： Philip M. Wallace , Thomas J. Brown
发明人： Philip M. Wallace , Thomas J. Brown
IPC分类号： A61K38/00 , A61K38/19 , C07K14/52 , A61F2/02
CPC分类号： C07K14/52 , A61K38/204
摘要： Oncostatin M is employed in methods to treat acute and chronic gastrointestinal inflammation, rheumatoid arthritis and multiple sclerosis.
摘要翻译：制瘤素M用于治疗急性和慢性胃肠道炎症，类风湿性关节炎和多发性硬化症的方法。

4. 发明授权

US5410971A Adjustable work station for the handicapped 失效
标题翻译：残疾人可调工作站
公开(公告)号：US5410971A
公开(公告)日：1995-05-02
申请号：US961226
申请日：1992-10-15
申请人： Jo-Ann Golden , Angelo Squatrito , Thomas J. Brown , Lawrence J. Yates , Kenneth Elfman
发明人： Jo-Ann Golden , Angelo Squatrito , Thomas J. Brown , Lawrence J. Yates , Kenneth Elfman
IPC分类号： A47B17/02 , A47F5/12
CPC分类号： A47B17/02 , A47B2200/0041 , A47B2200/13
摘要： A work station for the handicapped includes work surface structure, support structure, and structure for urging the work surface structure upward relative to said support structure. Engagement structure is provided for securing the work surface structure in a plurality of positions relative to the support structure. Release structure is provided for disengaging the engagement structure to permit repositioning of the work surface structure. The release structure is preferably a grip bar positioned substantially at the front of the work surface structure to facilitate operation by the handicapped.
摘要翻译：用于残疾人的工作站包括工作表面结构，支撑结构和用于相对于所述支撑结构向上推动工作表面结构的结构。提供接合结构用于将工作表面结构相对于支撑结构固定在多个位置。提供释放结构用于使接合结构脱离以允许工作表面结构的重新定位。释放结构优选地是基本位于工作表面结构的前部的把手杆，以便于残疾人的操作。

5. 发明授权

US5104086A Computer work station 失效
标题翻译：电脑工作站
公开(公告)号：US5104086A
公开(公告)日：1992-04-14
申请号：US692588
申请日：1991-04-29
申请人： Thomas B. Ramey, III. , Thomas J. Brown , James C. Brown
发明人： Thomas B. Ramey, III. , Thomas J. Brown , James C. Brown
IPC分类号： A47B23/00 , A47B21/04 , B41J29/15 , F16M13/00 , G06F1/16
CPC分类号： F16M13/00 , A47B21/045 , B41J29/15 , F16M11/046 , F16M11/2085 , F16M11/22 , F16M11/24 , A47B2200/0094 , Y10S248/918
摘要： A computer work station includes a generally planar base plate with an upstanding easel connected to the forward end of the base plate. The easal has a projecting lip which will support documents or other copy in an upright position for viewing by the user of the work station. In the preferred embodiment, the easel is connected to a support member which is slidably connected to the base plate to permit transverse lateral slidable movement of the easel with respect to the base plate. The easel is adjustably connected to the support member to permit vertical adjustable movement of the easel with respect to the base plate.
摘要翻译：计算机工作站包括大致平面的基板，其具有连接到基板的前端的直立架架。该容器具有突出的唇缘，其将支撑文件或其它副本，直立位置以供工作站的用户观看。在优选实施例中，画架连接到支撑构件，该支撑构件可滑动地连接到基板，以允许画架相对于基板的横向横向滑动运动。画架可调节地连接到支撑构件，以允许画架相对于基板垂直可调的运动。

6. 发明授权

US3527321A Ladder leveling device 失效
标题翻译：梯子平衡装置
公开(公告)号：US3527321A
公开(公告)日：1970-09-08
申请号：US3527321D
申请日：1969-03-17
申请人： THOMAS J BROWN
发明人： BROWN THOMAS J
IPC分类号： E06C7/44
CPC分类号： E06C7/44

7. 发明授权

US07832618B2 Termination bonding 有权
标题翻译：终止粘合
公开(公告)号：US07832618B2
公开(公告)日：2010-11-16
申请号：US11972074
申请日：2008-01-10
申请人： John L. Galvagni , Thomas J. Brown
发明人： John L. Galvagni , Thomas J. Brown
IPC分类号： B23K31/02
CPC分类号： B23K1/0016 , H01G2/065 , H01G4/228 , H01G13/006
摘要： Disclosed are methodologies for producing lead type electrical components. Components are placed in a lead frame with termination paste applied to selected portions of the component. Upon firing of the assembled lead frame and electrical components, the electrical components are concurrently terminated, and provided with strongly secured leads.
摘要翻译：公开了用于生产铅型电气部件的方法。将部件放置在引线框架中，并将端接膏施加到部件的选定部分。在组装的引线框架和电气部件点火时，电气部件同时终止，并且设置有牢固固定的引线。

8. 发明授权

US5814307A Method for regulating cell growth, leukocyte differentiation and tumor cell growth using Oncostatin M to stimulate synthesis of IL-6 失效
标题翻译：使用制瘤素M调节细胞生长，白细胞分化和肿瘤细胞生长刺激IL-6合成的方法
公开(公告)号：US5814307A
公开(公告)日：1998-09-29
申请号：US312205
申请日：1994-09-26
申请人： Philip M. Wallace , Thomas J. Brown
发明人： Philip M. Wallace , Thomas J. Brown
IPC分类号： A61K38/00 , A61K38/19 , A61K38/22 , A61K47/48 , A61P7/06 , A61P35/00 , A61K38/18 , C07K14/54
CPC分类号： A61K47/48269 , A61K38/1816 , A61K38/193 , A61K38/196 , A61K38/202 , A61K38/204 , A61K47/48423
摘要： The present invention relates to methods of using oncostatin M (OM). In particular, it relates to the use of OM to stimulate interleukin 6 (IL-6) synthesis in target cells, especially human endothelial cells. The resultant IL-6, in turn, may perform a variety of functions such as cell growth regulation, leukocyte differentiation, and tumor inhibition. Furthermore, the present invention also relates to the use of OM to treat cytopenias, including anemia and thrombocytopoiesis, and to increase tolerance to irradiation and cytotoxic drugs. Therefore, the methods of the invention may have a wide range of applications, including, but not limited to, the inhibition of tumor growth, the treatment of cytopenias, and to increase the tolerance to radio- and chemotherapy. OM may be used in combination with various cytokines, including erythropoietin, colony-stimulating factors, interleukin-3 or thrombopoietin.
摘要翻译：本发明涉及使用制瘤素M（OM）的方法。特别地，它涉及使用OM来刺激靶细胞，特别是人内皮细胞中的白细胞介素6（IL-6）合成。所得到的IL-6又可以进行各种功能，例如细胞生长调节，白细胞分化和肿瘤抑制。此外，本发明还涉及OM用于治疗血细胞减少症（包括贫血和血小板生成）并增加对照射和细胞毒性药物的耐受性的用途。因此，本发明的方法可以具有广泛的应用，包括但不限于抑制肿瘤生长，治疗血细胞减少以及增加对放射和化学疗法的耐受性。 OM可以与各种细胞因子，包括促红细胞生成素，集落刺激因子，白介素-3或血小板生成素组合使用。

9. 发明授权

US5341793A Drawer attachment for barbecue grills 失效
标题翻译：烤箱附件烤箱
公开(公告)号：US5341793A
公开(公告)日：1994-08-30
申请号：US103668
申请日：1993-08-10
申请人： Thomas J. Brown
发明人： Thomas J. Brown
IPC分类号： A47J37/07 , A47J37/00 , F24C3/00
CPC分类号： A47J37/0786
摘要： An apparatus for use with a gas grill cart which comprises a cutting board and a drawer for preparation of food and storage of grilling accessories. The apparatus is adapted for use with grill carts having a base and a four-posted vertically extending structure having arms extending perpendicularly from each post. The invention is adapted to be placed between two of the arms previously having wooden slots extending therebetween and is comprised of a cutting board which has a length greater than the length of the space between the arms of the cart. The cutting board has guides attached to the underside thereof for engagement with a drawer which is similarly held on the cart via the engagement of the cutting board with the arms. The drawer has a locking device thereon for engagement with a cutout in one of the guides attached to the cutting board. As such, the drawer cannot be fully removed from the slots of the guides and, therefore, accidental spillage of the drawer and its contents is prevented. The cutting board can be permanently attached to the arms of the cart via screws or the like used to previously attach the slats. The cutting board can be used to cut and otherwise prepare food to be grilled and the drawer can be used to store grilling accessories such as brushes and spatulas.
摘要翻译：一种与燃气格栅推车一起使用的装置，其包括切割板和用于制备食物和储存烧烤配件的抽屉。该装置适用于具有底座的格栅推车和具有从每个柱垂直延伸的臂的四张垂直延伸结构。本发明适于放置在之前具有在其间延伸的木制狭槽的两个臂之间，并且包括具有大于推车臂之间的空间长度的切割板。切割板具有附接到其下侧的引导件，用于与通过切割板与臂的接合类似地保持在推车上的抽屉接合。抽屉在其上具有锁定装置，用于与附接到切割板的导轨之一中的切口接合。因此，抽屉不能从引导件的槽中完全移除，因此防止了抽屉及其内容物的意外泄漏。切割板可以通过用于预先连接板条的螺钉等永久地附接到推车的臂上。砧板可以用来切割和准备要烧烤的食物，并且抽屉可以用来存放烧烤配件如刷子和铲子。

10. 发明授权

US5340925A Normal human growth regulatory receptor for TGF-.beta. 失效
标题翻译： TGF-β的正常人生长调节受体
公开(公告)号：US5340925A
公开(公告)日：1994-08-23
申请号：US900511
申请日：1992-06-17
申请人： Mario N. Lioubin , Thomas J. Brown , Anthony F. Purchio
发明人： Mario N. Lioubin , Thomas J. Brown , Anthony F. Purchio
IPC分类号： C07K14/705 , C07K1/22 , C07K14/00 , C07K14/71 , C07K14/715 , C12N15/09 , C12P21/02 , C12R1/91 , C07K15/00
CPC分类号： C07K14/71
摘要： Type III TGF-.beta. receptor is identified in and purified from normal human embryonic palatal mesenchyme (HEPM) cells and the purified product characterized structurally and functionally. HEPM cells were found to express high levels of the type III TGF-.beta. receptor and were found to significantly down-regulate two classes of TGF-.beta. receptor binding site. Purification of the type III TGF-.beta. receptor from solubilized HEPM cell membranes by affinity chromatography yielded a biologically active protein of about 205 kd which specifically binds both the recombinant and natural forms of TGF-.beta.1 and TGF-.beta.2, with affinity dissociation constants in the picomolar range.
摘要翻译： III型TGF-β受体在正常人胚胎腭裂间质（HEPM）细胞中鉴定并纯化，纯化的产物在结构和功能上表征。发现HEPM细胞表达高水平的III型TGF-β受体，并被发现显着下调两类TGF-β受体结合位点。通过亲和层析从溶解的HEPM细胞膜中纯化III型TGF-β受体，产生约205kd的生物活性蛋白，其特异性结合重组和天然形式的TGF-β1和TGF-β2，具有亲和解离常数在皮摩摩范围内。

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