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1. 发明授权

US08629147B2 Heterocyclic compounds useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders 有权
标题翻译：可用于治疗肿瘤性疾病，炎症性疾病和免疫调节性疾病的杂环化合物
公开(公告)号：US08629147B2
公开(公告)日：2014-01-14
申请号：US11593191
申请日：2006-11-02
申请人： Alexey Vyacheslavovich Anikin , Vidyasagar Reddy Gantla , Vlad Edward Gregor , Luyong Jiang , Yahua Liu , Danny Peter Claude McGee , Charles Chamchoumis Mikel , Jason Conrad Pickens , Thomas Roy Webb , Zheng Yan , Tong Zhu , Aleksander Kadushkin , Sergey Sviridov , Sergey Zozulya , Alexander Chucholowski , Douglas Eric McGrath
发明人： Alexey Vyacheslavovich Anikin , Vidyasagar Reddy Gantla , Vlad Edward Gregor , Luyong Jiang , Yahua Liu , Danny Peter Claude McGee , Charles Chamchoumis Mikel , Jason Conrad Pickens , Thomas Roy Webb , Zheng Yan , Tong Zhu , Aleksander Kadushkin , Sergey Sviridov , Sergey Zozulya , Alexander Chucholowski , Douglas Eric McGrath
IPC分类号： A61K31/497 , A61K31/47 , A61K31/445
CPC分类号： C07D401/04 , C07D235/18 , C07D235/20 , C07D401/10 , C07D401/14 , C07D403/04 , C07D403/14 , C07D471/10 , C07D487/04 , C07D487/10 , C07D491/04 , C07D495/04
摘要： The present invention provides compounds capable of modulating tyrosine kinases, compositions comprising the compounds and methods of their use.
摘要翻译：本发明提供了能够调节酪氨酸激酶的化合物，包含该化合物的组合物及其使用方法。

2. 发明授权

US08467814B2 SMS shortcode allocation 有权
标题翻译：短信短码分配
公开(公告)号：US08467814B2
公开(公告)日：2013-06-18
申请号：US11853618
申请日：2007-09-11
申请人： Jiuhe Gan , Tong Zhu , Kenneth Tsz Ho , Zhaowei Charlie Jiang , Venkata Narasimha Rao Yerubandi
发明人： Jiuhe Gan , Tong Zhu , Kenneth Tsz Ho , Zhaowei Charlie Jiang , Venkata Narasimha Rao Yerubandi
IPC分类号： H04W4/00
CPC分类号： H04W4/12 , H04L51/38
摘要： A system, apparatus, and method are directed towards managing short code allocation policies across a plurality of different carriers for multiple applications. Each carrier provides to a centralized routing service a short code policy that includes an extension allocation policy. The extension allocation policy may specify whether the extensions are allocated based on a dynamical recycle allocation, a range recycle allocation, a pass-through allocation, or a re-usekey based allocation policy, or other mechanism. When a message is sent from an application, a carrier is determined to send the message to a destination mobile device. The carrier's short code policy, including the extension allocation policy, is then used to select how to allocate and/or re-allocate a short code and extension for use with the message. The message may then be modified to include the selected short code and extension, and is then sent using the determined network carrier.
摘要翻译：系统，装置和方法旨在管理用于多个应用的多个不同载波的短代码分配策略。每个运营商向集中式路由服务提供包括扩展分配策略的短代码策略。扩展分配策略可以基于动态循环分配，范围回收分配，直通分配或基于重用键分配策略或其他机制来指定分机是否被分配。当从应用发送消息时，确定运营商将消息发送到目的地移动设备。然后，运营商的短代码策略（包括分机分配策略）用于选择如何分配和/或重新分配用于消息的短代码和分机。然后可以修改消息以包括所选择的短代码和扩展，然后使用所确定的网络载体进行发送。

3. 发明申请

US20130025000A1 PROMOTER FOR REGULATION OF GENE EXPRESSION IN PLANT ROOTS 审中-公开
标题翻译：用于调节植物基因表达的促销者
公开(公告)号：US20130025000A1
公开(公告)日：2013-01-24
申请号：US13514119
申请日：2010-12-07
申请人： Tong Zhu , Vance Cary Kramer , Anthony Todd Richmond
发明人： Tong Zhu , Vance Cary Kramer , Anthony Todd Richmond
IPC分类号： C12N15/113 , A01H5/10 , A01H5/00 , C12N15/82 , C12N5/10
CPC分类号： C12N15/8227 , C07K14/415
摘要： The invention is directed to a promoter isolated from maize. The promoter of the invention have particular utility in driving root preferred expression, specifically root-cap expression, of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given transgenic plant. The invention is also drawn to DNA molecules comprising the promoter of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
摘要翻译：本发明涉及从玉米分离的启动子。本发明的启动子在驱动给定转基因植物赋予增加的农艺，园艺和/或杀虫特性的异源基因的根优选表达，特别是根帽表达方面具有特别的用途。本发明还涉及包含本发明启动子的DNA分子和含有可操作地连接到异源基因或基因的本发明启动子的DNA分子的转化植物组织及其种子。

4. 发明授权

US08170584B2 Providing an actionable event in an intercepted text message for a mobile device based on customized user information 有权
标题翻译：基于定制的用户信息，在移动设备的拦截文本消息中提供可操作的事件
公开(公告)号：US08170584B2
公开(公告)日：2012-05-01
申请号：US11422534
申请日：2006-06-06
申请人： Ben Kim , Irvin Henderson , Tong Zhu
发明人： Ben Kim , Irvin Henderson , Tong Zhu
IPC分类号： H04W24/00
CPC分类号： H04L67/306 , G06Q30/02 , H04L51/063 , H04L51/38 , H04L63/166 , H04W4/00 , H04W4/14 , H04W4/18 , H04W8/18
摘要： A network device, method, and apparatus are directed towards intercepting a message, such as an SMS, EMS, MMS message, email message, or the like, from a source device directed towards a mobile device. The intercepted message's contents are analyzed. In addition, a mobile user profile is determined from characteristics of the mobile device and tracked usage of a mobile user of the mobile device. An actionable event may then be inserted into the intercepted message based, in part, on the analysis and the mobile user profile. The modified message is then provided to the mobile device, where the mobile user may select the actionable event to receive non-requested content.
摘要翻译：网络设备，方法和设备被指向从指向移动设备的源设备拦截诸如SMS，EMS，MMS消息，电子邮件消息等的消息。对截取的消息内容进行分析。此外，移动用户简档由移动设备的特征和移动设备的移动用户的跟踪使用来确定。然后可以部分地基于分析和移动用户简档将可操作的事件插入被拦截的消息中。然后将修改的消息提供给移动设备，其中移动用户可以选择可操作事件来接收未请求的内容。

5. 发明授权

US08063225B2 Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders 有权
标题翻译：可用于治疗肿瘤性疾病，炎症性疾病和免疫调节性疾病的三环类化合物衍生物
公开(公告)号：US08063225B2
公开(公告)日：2011-11-22
申请号：US11891604
申请日：2007-08-10
申请人： Vlad E. Gregor , Yahua Liu , Alexey Anikin , Danny Peter Claude McGee , Charles Mikel , Douglas Eric McGrath , Goverdhan Reddy Vavilala , Jason C. Pickens , Alexander Kadushkin , Luyong Jiang , Mohan Santhanam Thiruvazhi , Sergey Zozulya , Rajendran Vairagoundar , Tong Zhu , Alexander Chucholowski , Thomas Webb , Vidyasagar Reddy Gantla , Zheng Yan
发明人： Vlad E. Gregor , Yahua Liu , Alexey Anikin , Danny Peter Claude McGee , Charles Mikel , Douglas Eric McGrath , Goverdhan Reddy Vavilala , Jason C. Pickens , Alexander Kadushkin , Luyong Jiang , Mohan Santhanam Thiruvazhi , Sergey Zozulya , Rajendran Vairagoundar , Tong Zhu , Alexander Chucholowski , Thomas Webb , Vidyasagar Reddy Gantla , Zheng Yan
IPC分类号： C07D401/00 , A61K31/44
CPC分类号： C07D487/04
摘要： Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.
摘要翻译：提供式（I）化合物或其调节酪氨酸激酶活性的立体异构体，互变异构体，盐，水合物或前药，包含该化合物的组合物及其使用方法。

6. 发明申请

US20100275333A1 ABIOTIC STRESS RESPONSIVE POLYNUCLEOTIDES AND POLYPEPTIDES 审中-公开
标题翻译：生物应力响应多核苷酸和多肽
公开(公告)号：US20100275333A1
公开(公告)日：2010-10-28
申请号：US12827087
申请日：2010-06-30
申请人： Joel Kreps , Steven P. Briggs , Stephen A. Goff , Fumiaki Katagiri , Todd Moughamer , Nicholas Provart , Darrell Ricke , Tong Zhu , Robert Dietrich , Bret Cooper
发明人： Joel Kreps , Steven P. Briggs , Stephen A. Goff , Fumiaki Katagiri , Todd Moughamer , Nicholas Provart , Darrell Ricke , Tong Zhu , Robert Dietrich , Bret Cooper
IPC分类号： A01H5/00 , C07H21/00 , C12N15/63 , C07K14/415 , C12N5/10 , C12N1/21 , C12N1/19
CPC分类号： C07K14/415 , C12N15/8271
摘要： Abiotic stress responsive polynucleotides and polypeptides are disclosed. Also disclosed are vectors, expression cassettes, host cells, and plants containing such polynucleotides. Also provided are methods for using such polynucleotides and polypeptides, for example, to alter the responsiveness of a plant to abiotic stress.
摘要翻译：公开了非生物应激反应多核苷酸和多肽。还公开了载体，表达盒，宿主细胞和含有此类多核苷酸的植物。还提供了使用这种多核苷酸和多肽的方法，例如改变植物对非生物胁迫的响应性。

7. 发明授权

US07777097B2 Plant disease resistance genes 有权
标题翻译：植物抗病基因
公开(公告)号：US07777097B2
公开(公告)日：2010-08-17
申请号：US10482526
申请日：2002-06-21
申请人： Jane Glazebrook , Steven P. Briggs , Bret Cooper , Stephen A. Goff , Todd Moughamer , Fumiyaki Katagiri , Joel Kreps , Nicholas Provart , Darrell Ricke , Tong Zhu
发明人： Jane Glazebrook , Steven P. Briggs , Bret Cooper , Stephen A. Goff , Todd Moughamer , Fumiyaki Katagiri , Joel Kreps , Nicholas Provart , Darrell Ricke , Tong Zhu
IPC分类号： C12N15/09 , C12N15/82 , A01H5/00
CPC分类号： C07H21/04 , C07K14/415 , C12N9/0008 , C12N15/8271 , C12N15/8273 , C12Q1/6895 , C12Q2600/13 , C12Q2600/156 , C12Q2600/158
摘要： The invention relates to methods of producing plants with increased resistance to pathogen infection by expressing disease resistance genes in the plants and transgenic plants having enhanced pathogen resistance.
摘要翻译：本发明涉及通过在植物中表达抗病基因和具有增强的病原体抗性的转基因植物来生产对病原体感染抗性增加的植物的方法。

8. 发明授权

US07715990B2 Probe correction for gene expression level detection 有权
标题翻译：基因表达水平检测的探针校正
公开(公告)号：US07715990B2
公开(公告)日：2010-05-11
申请号：US10500587
申请日：2003-01-17
申请人： Guangzhou Zou , Hur-Song Chang , Yiping Fan , Fan Long , Xun Wang , Tong Zhu
发明人： Guangzhou Zou , Hur-Song Chang , Yiping Fan , Fan Long , Xun Wang , Tong Zhu
IPC分类号： G01N33/483
CPC分类号： G06F19/20 , C12Q1/6837 , C12Q2600/158
摘要： Individual probes on micro-arrays are re-scaled and corrected with a set of probe dependent coefficients derived from genomic-DNA hybridization signals. A dynamic range for gDNA binding is determined by measuring a concentration signal curve. Signals for each probe are measured during multiple hybridizations within a linear range. Concentration insensitive probes are then found for two sets of experiments. Probes are discarded based on a threshold compared to their standard deviation divided by their average in each set. The correction coefficients are used to calculate a corrected intensity for each probe. Probes having high uncertainty (0.5 in one embodiment) are discarded. A weighting factor for each probe is determined along with an uncertainty factor. Finally, a call for each gene is made, such as absent, marginal or present.
摘要翻译：使用从基因组DNA杂交信号衍生的一组探针依赖系数对微阵列上的单个探针进行重新定标和校正。通过测量浓度信号曲线确定gDNA结合的动态范围。在线性范围内的多次杂交期间测量每个探针的信号。然后发现两组实验的浓度不敏感探针。探针根据其标准偏差除以每组中的平均值的阈值进行丢弃。校正系数用于计算每个探针的校正强度。具有高不确定度的探针（在一个实施例中为0.5）被丢弃。确定每个探头的加权系数以及不确定因素。最后，调用每个基因，如缺席，边缘或存在。

9. 发明申请

US20090183283A1 RICE PROMOTERS FOR REGULATION OF PLANT EXPRESSION 审中-公开
标题翻译：用于调节植物表达的米饭促销者
公开(公告)号：US20090183283A1
公开(公告)日：2009-07-16
申请号：US12395171
申请日：2009-02-27
申请人： Paul Budworth , Todd Moughamer , Steven P. Briggs , Bret Cooper , Jane Glazebrook , Stephen Arthur Goff , Fumiaki Katagiri , Jeol Kreps , Nicholas Provart , Darrell Ricke , Tong Zhu
发明人： Paul Budworth , Todd Moughamer , Steven P. Briggs , Bret Cooper , Jane Glazebrook , Stephen Arthur Goff , Fumiaki Katagiri , Jeol Kreps , Nicholas Provart , Darrell Ricke , Tong Zhu
IPC分类号： A01H5/00 , C12N15/11 , C12N15/00 , C12N5/04
CPC分类号： C07K14/415 , C12N15/8234 , C12Q1/6895 , C12Q2600/158
摘要： The present invention provides promoters from plants capable of driving gene expression in plant cells. The promoters vary in strength and in tissue specificity, and can be used to facilitate the development of transgenic plants in which tissue preferred expression, constitutive expression, and the strength of transgene expression is either more or less critical.
摘要翻译：本发明提供能够驱动植物细胞中基因表达的植物的启动子。启动子在强度和组织特异性方面不同，并且可以用于促进其中组织优选表达，组成型表达和转基因表达的强度或多或少关键的转基因植物的开发。

10. 发明申请

US20090109978A1 Application interface for global mobile message delivery 有权
标题翻译：用于全球移动邮件传送的应用程序界面
公开(公告)号：US20090109978A1
公开(公告)日：2009-04-30
申请号：US11981980
申请日：2007-10-31
申请人： Tong Zhu , Zhaowei Charlie Jiang , Ben Kim , Kenneth Tsz Ho , Jiuhe Gan , Venkata Narasimha Rao Yerubandi , Daniel John Woods
发明人： Tong Zhu , Zhaowei Charlie Jiang , Ben Kim , Kenneth Tsz Ho , Jiuhe Gan , Venkata Narasimha Rao Yerubandi , Daniel John Woods
IPC分类号： H04L12/28 , H04L12/56 , H04L12/66 , H04M1/00
CPC分类号： H04W4/12 , H04L51/38
摘要： A device, system, and method are directed towards communicating mobile information over a network. A mobile message (MM) is generated by an Internet Protocol (IP) enabled application interface. The MM may include advertising information. The MM is received at a routing server and comprises a destination phone number and/or advertising information. If the MM is determined to be locally processed, the routing server selectively routes the MM to a destination carrier associated with the destination phone number. If the MM is determined to be remotely processed, the MM is recursively forwarded until the MM reaches another routing server associated with the destination phone number. The other routing server is configured to selectively route the MM to the destination carrier. A response MM may be received at a boundary routing server. The response MM may be sent to the API if at least a portion of the response MM matches information associated with the MM.
摘要翻译：设备，系统和方法旨在通过网络传送移动信息。移动消息（MM）由启用因特网协议（IP）的应用接口生成。 MM可以包括广告信息。 MM在路由服务器处被接收并且包括目的地电话号码和/或广告信息。如果确定MM被本地处理，则路由选择服务器选择性地将MM路由到与目的地电话号码相关联的目的地载波。如果确定MM被远程处理，则MM被递归转发，直到MM到达与目的地电话号码相关联的另一个路由服务器。另一路由服务器被配置为选择性地将MM路由到目的地载波。可以在边界路由服务器处接收响应MM。如果响应MM的至少一部分匹配与MM相关联的信息，则可以将响应MM发送到API。

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