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1. 发明专利

AU5277199A Supergravitational field vortex reactor and the use thereof 未知
公开(公告)号：AU5277199A
公开(公告)日：2000-10-23
申请号：AU5277199
申请日：1999-08-12
申请人： XIAOJUN PAN , WUYI WANG
发明人： PAN XIAOJUN , WANG WUYI
IPC分类号： B01J19/18 , B01D3/30

2. 发明申请

US20120297505A1 TRANSGENIC PLANTS HAVING INCREASED BIOMASS 审中-公开
标题翻译：具有增加生物量的转基因植物
公开(公告)号：US20120297505A1
公开(公告)日：2012-11-22
申请号：US13385000
申请日：2010-07-20
申请人： Chuan-Yin Wu , Han-Suk Kim , Gerard Magpantay , Fasong Zhou , Julissa Sosa , Greg Nadzan , Roger I. Pennell , Mircea Achiriloaie , Wuyi Wang
发明人： Chuan-Yin Wu , Han-Suk Kim , Gerard Magpantay , Fasong Zhou , Julissa Sosa , Greg Nadzan , Roger I. Pennell , Mircea Achiriloaie , Wuyi Wang
IPC分类号： A01H5/00 , C12N15/82 , C12N5/04 , C12N5/10 , A01H5/10
CPC分类号： C07K14/415 , C12N15/8261 , Y02A40/146
摘要： Methods and materials for modulating biomass levels in plants are disclosed. For example, nucleic acids encoding biomass-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased biomass levels and plant products produced from plants having increased biomass levels.
摘要翻译：公开了调节植物生物量的方法和材料。例如，公开了编码生物质调节多肽的核酸以及使用这种核酸来转化植物细胞的方法。还公开了具有增加的生物量水平的植物和由具有增加的生物量水平的植物产生的植物产物。

3. 发明授权

US07985769B2 Compounds and methods for the treatment or prevention of Flavivirus infections 失效
标题翻译：用于治疗或预防黄病毒感染的化合物和方法
公开(公告)号：US07985769B2
公开(公告)日：2011-07-26
申请号：US11042442
申请日：2005-01-26
申请人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen Ba , Oswy Z. Pereira , Thumkunta Jagadeeswar Reddy , Mohammad Arshad Siddiqui , Wuyi Wang , Constanin Yannopoulos
发明人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen Ba , Oswy Z. Pereira , Thumkunta Jagadeeswar Reddy , Mohammad Arshad Siddiqui , Wuyi Wang , Constanin Yannopoulos
IPC分类号： A61K31/35 , C07D333/38 , C07D333/36
CPC分类号： C07D409/04 , A61K31/20 , A61K31/341 , A61K31/343 , A61K31/381 , A61K31/426 , A61K45/06 , C07D333/38 , C07D409/06 , C07D409/12 , C07D409/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D419/14 , C07D471/10 , C07D495/04
摘要： The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
摘要翻译：本发明提供由式I表示的新化合物：或其药学上可接受的盐，用于治疗黄病毒科病毒感染。

4. 发明授权

US07541355B2 Conversion process for 2,3-benzodiazepine enantiomers 有权
标题翻译： 2,3-苯并二氮杂异对映体的转化过程
公开(公告)号：US07541355B2
公开(公告)日：2009-06-02
申请号：US11135100
申请日：2005-05-23
申请人： Yong Victoria Wei , Naidaong Ye , Kimm Galbraith , Jianfeng Shi , Wuyi Wang , Yungen Xu , Mallikarjun Reddy Ravi
发明人： Yong Victoria Wei , Naidaong Ye , Kimm Galbraith , Jianfeng Shi , Wuyi Wang , Yungen Xu , Mallikarjun Reddy Ravi
IPC分类号： A61P25/22 , A61K31/551 , C07D243/02
CPC分类号： C07D243/02
摘要： Methods for the racemization of an enantiomer of a 2,3-benzodiazepine molecule into the corresponding racemic mixture under either basic or acidic conditions are described. Furthermore, the invention relates to the conversion of an enantiomer of tofisopam or its metabolites to the corresponding opposite enantiomer.
摘要翻译：描述了2,3-苯并二氮杂分子的对映异构体在碱性或酸性条件下相应外消旋混合物外消旋化的方法。此外，本发明涉及将替泊伐姆或其代谢物的对映异构体转化为相应的对映异构体。

5. 发明申请

US20060264421A1 Conversion process for 2,3-benzodiazepine enantiomers 有权
公开(公告)号：US20060264421A1
公开(公告)日：2006-11-23
申请号：US11135100
申请日：2005-05-23
申请人： Yong Wei , Naidong Ye , Kimm Galbraith , Jianfeng Shi , Wuyi Wang , Yungen Xu , Mallikarjun Ravi
发明人： Yong Wei , Naidong Ye , Kimm Galbraith , Jianfeng Shi , Wuyi Wang , Yungen Xu , Mallikarjun Ravi
IPC分类号： A61K31/5513 , C07D487/02
CPC分类号： C07D243/02
摘要： Methods for the racemization of an enantiomer of a 2,3-benzodiazepine molecule into the corresponding racemic mixture under either basic or acidic conditions are described. Furthermore, the invention relates to the conversion of an enantiomer of tofisopam or its metabolites to the corresponding opposite enantiomer.

6. 发明授权

US06337319B1 &mgr;-Selective opioid peptides 失效
标题翻译： mu-选择性阿片肽
公开(公告)号：US06337319B1
公开(公告)日：2002-01-08
申请号：US08718585
申请日：1996-10-02
申请人： Wuyi Wang
发明人： Wuyi Wang
IPC分类号： A61K3807
CPC分类号： C07K5/1027 , A61K38/00 , C07K5/1016
摘要： This invention relates to novel opioid peptides for the treatment of pain as well as a method for the preparation thereof and pharmaceutically acceptable compositions comprising these peptides. The invention also relates to methods for controlling pain in patients using compositions of the invention and the use of said compounds in the preparation of formulations effective in pain treatment. The peptides of this invention have a high degree of selectivity for the &mgr;-opioid receptor. The peptides of the present invention are particularly well-suited as analgesic agents acting substantially on peripheral &mgr;-opioid receptors. Because these peptides act peripherally, they substantially avoid producing side effects normally associated with central analgesic action.
摘要翻译：本发明涉及用于治疗疼痛的新型阿片类肽以及其制备方法和包含这些肽的药学上可接受的组合物。本发明还涉及使用本发明组合物治疗患者疼痛的方法以及所述化合物在制备有效治疗疼痛的配方中的用途。本发明的肽对μ-阿片受体具有高度的选择性。本发明的肽特别适合作为基本上作用于外周mu-阿片受体的止痛剂。因为这些肽在外周作用，它们基本上避免产生通常与中枢镇痛作用相关的副作用。

7. 发明授权

US5736523A Antineoplastic heteronapthoquinones 失效
标题翻译：抗肿瘤异二氢醌
公开(公告)号：US5736523A
公开(公告)日：1998-04-07
申请号：US401493
申请日：1995-03-10
申请人： Giorgio Attardo , Tibor Breining , Marc Courchesne , Serge Lamothe , Jean-Fran.cedilla.ois Lavallee , Dieu Nguyen , Rabindra Rej , Yves St-Denis , Wuyi Wang , Yao-Chang Xu , France Barbeau , Elaine Lebeau , Jean Louis Kraus
发明人： Giorgio Attardo , Tibor Breining , Marc Courchesne , Serge Lamothe , Jean-Fran.cedilla.ois Lavallee , Dieu Nguyen , Rabindra Rej , Yves St-Denis , Wuyi Wang , Yao-Chang Xu , France Barbeau , Elaine Lebeau , Jean Louis Kraus
IPC分类号： C07D311/76 , C07D311/92 , C07D335/08 , C07D493/04 , C07H15/252 , C07H17/00 , C07H17/04 , C07H17/08 , A61K31/70 , C07H15/24
CPC分类号： C07D311/76 , C07D311/92 , C07D335/08 , C07D493/04 , C07H15/252 , C07H17/00 , C07H17/04 , C07H17/08
摘要： This invention relates to a naphthoquinone derivatives, to processes and to intermediates for preparing these derivatives, to pharmaceutical composition and to the use of these derivatives as antitumor agents in mammals.
摘要翻译：本发明涉及萘醌衍生物，制备这些衍生物的方法和中间体，以及这些衍生物作为哺乳动物抗肿瘤剂的用途。

8. 发明授权

US09568237B2 Method and apparatus for rapidly cooling a gem, including two stage cooling 有权
标题翻译：用于快速冷却宝石的方法和装置，包括两级冷却
公开(公告)号：US09568237B2
公开(公告)日：2017-02-14
申请号：US13920941
申请日：2013-06-18
申请人： Matt Hall , Ren Lu , Wuyi Wang
发明人： Matt Hall , Ren Lu , Wuyi Wang
IPC分类号： G01N21/00 , F25D3/10 , F25D19/00 , G01N21/03 , G01N21/31 , G01N21/87 , G01N21/3563
CPC分类号： F25B19/005 , F25D3/10 , F25D19/006 , G01N21/0332 , G01N21/31 , G01N21/3563 , G01N21/87 , G01N2021/0335 , G01N2021/3155 , G01N2201/065
摘要： A cooling apparatus includes a container configured to contain a coolant within a space. The apparatus further includes a cooling block positioned substantially within the space and having a high heat capacity such that the space not occupied by the cooling block is filled with a coolant to a level at or below the top of the cooling block, and a placement structure having high thermal conductivity positioned on top of the cooling block and outside of the space. A method for cooling an object is also provided, which includes inserting a coolant into a container configured to contain the coolant within a space, and placing the object on a placement structure outside the space. For this method, the placement structure has a high thermal conductivity and is coupled to a cooling block, the cooling block having a high heat capacity and positioned substantially within the space. A two-stage cooling apparatus and method is also described.
摘要翻译：一种冷却装置包括：容器，其构造成在空间内容纳冷却剂。该装置还包括基本上位于该空间内并且具有高热容量的冷却块，使得未被冷却块占据的空间用冷却剂填充到冷却块的顶部或下方的水平面，以及放置结构具有高的导热性位于冷却块的顶部并且位于空间外部。还提供了一种用于冷却物体的方法，其包括将冷却剂插入构造成在空间内容纳冷却剂的容器中，并将物体放置在空间外部的放置结构上。对于该方法，放置结构具有高导热性并且耦合到冷却块，该冷却块具有高的热容并且基本位于该空间内。还描述了两级冷却装置和方法。

9. 发明申请

US20110023193A1 DROUGHT AND HEAT TOLERANCE IN PLANTS 审中-公开
标题翻译：在植物中的耐旱和耐热性
公开(公告)号：US20110023193A1
公开(公告)日：2011-01-27
申请号：US12856204
申请日：2010-08-13
申请人： Cory Christensen , Wuyi Wang , Dennis Yang
发明人： Cory Christensen , Wuyi Wang , Dennis Yang
IPC分类号： A01H5/00 , C12N5/10
CPC分类号： C12N15/8201 , A01H5/10 , C07K14/415 , C12N15/8271 , C12N15/8273
摘要： Methods and materials for modulating heat and/or drought tolerance in plants are disclosed. For example, nucleic acids encoding heat and/or drought-tolerance polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased heat and/or drought tolerance and plant products produced from plants having increased heat and/or drought tolerance.
摘要翻译：公开了用于调节植物中热和/或耐旱性的方法和材料。例如，公开了编码热和/或耐旱多肽的核酸以及使用这种核酸来转化植物细胞的方法。还公开了具有增加的热和/或耐旱性的植物和由具有增加的热和/或耐旱性的植物产生的植物产品。

10. 发明申请

US20090172840A1 NUCLEOTIDE SEQUENCES AND CORRESPONDING POLYPEPTIDES CONFERRING AN ALTERED FLOWERING TIME IN PLANTS 失效
标题翻译：核苷酸序列和相应的聚糖在植物中占用更换的花期
公开(公告)号：US20090172840A1
公开(公告)日：2009-07-02
申请号：US12281616
申请日：2007-03-14
申请人： Wuyi Wang , Kenneth A. Feldmann
发明人： Wuyi Wang , Kenneth A. Feldmann
IPC分类号： C12N15/82 , A01H5/00 , C07H21/04 , C12N15/63 , C12N5/10 , A23L1/212 , A23K1/00 , C12Q1/68
CPC分类号： C07K14/415 , C12N15/827
摘要： The present invention relates to isolated nucleic acid molecules and their corresponding encoded polypeptides able to confer the trait of altered flowering time in plants. The present invention further relates to using the nucleic acid molecules and polypeptides to make transgenic plants, plant cells, plant materials or seeds of a plant having flowering times that are altered with respect to wild-type plants grown under similar conditions. Altered flowering time includes both plants having an early flowering time and a late flowering time with respect to wild-type plants grown under similar conditions. Flowering time in plants may be altered either with respect to the normal time at which wild-type plants flower within their normal life cycle or altered temporally such that the entire life cycle of the plant is accelerated or prolonged using the nucleic acid molecules and polypeptides of the present invention.
摘要翻译：本发明涉及分离的核酸分子及其相应的编码多肽，其能够赋予植物中改变的开花时间的性状。本发明还涉及使用核酸分子和多肽来制备具有相对于在相似条件下生长的野生型植物改变的花期的植物的转基因植物，植物细胞，植物材料或种子。改变的开花时间包括相对于在类似条件下生长的野生型植物具有早期开花时间和延迟开花时间的植物。植物中的开花时间可以相对于野生型植物在其正常生命周期内花期或在时间上变化的正常时间而改变，使得植物的整个生命周期被加速或延长，使用核酸分子和多肽本发明。

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