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1. 发明专利

BR112018013214A2 métodos para a produção de produtos de fermentação a partir de matéria-prima 未知
公开(公告)号：BR112018013214A2
公开(公告)日：2018-12-11
申请号：BR112018013214
申请日：2016-12-20
申请人： DANISCO US INC , GANG DUAN , KANNAN RANGANATHAN , VIPUL GOHEL , XIAOPING ZHANG , XUAN LIU , YING QIAN
发明人： GANG DUAN , KANNAN RANGANATHAN , VIPUL GOHEL , XIAOPING ZHANG , XUAN LIU , YING QIAN
IPC分类号： C12P7/06 , C12P7/08 , C12P7/10 , C12P19/00
摘要： são descritos métodos e composições para produção melhorada de pelo menos um produto de fermentação resultante da fermentação de meio contendo açúcar obtido a partir de uma ou mais matérias-primas. as composições reveladas no presente documento compreendem trealase.

2. 发明申请

WO2012027226A1 A FOOD PRODUCT COMPRISING A LOW TEMPERATURE RICE PROTEIN CONCENTRATE 审中-公开
标题翻译：一种包含低温玉米蛋白浓缩物的食品
公开(公告)号：WO2012027226A1
公开(公告)日：2012-03-01
申请号：PCT/US2011/048448
申请日：2011-08-19
申请人： DANISCO US INC. , DUAN, Gang , JACOBSEN, Kathleen Burns , SHETTY, Jayarama K. , YING, Qian , WILSON, Troy
发明人： DUAN, Gang , JACOBSEN, Kathleen Burns , SHETTY, Jayarama K. , YING, Qian , WILSON, Troy
IPC分类号： A23L1/305 , A23J1/12 , A23J3/14 , A23J3/34 , A23K1/00 , A23K1/16 , A23G3/54 , A23G1/54
CPC分类号： A23J3/346 , A23G1/54 , A23G3/54 , A23J1/125 , A23J3/14 , A23K20/147 , A23L33/185 , A23V2002/00 , C12Y302/01001 , C12Y302/01003 , A23V2250/548
摘要： Rice protein concentrates prepared at low temperature exhibit improved functionality and beneficial physiological benefits, including lowered cholesterol and enhanced lactic acid dehydrogenase activity, without an increase in blood urea nitrogen. The rice protein concentration could be made into a wet dough with comparatively less water than a soy protein concentrate. Use of the rice protein concentrate thus improved processing steps in the formulation of a food article containing the concentrate. The food product advantageously shows an extending shelf life and improved palatable texture.
摘要翻译：在低温下制备的大米蛋白浓缩物显示改善的功能和有益的生理益处，包括降低的胆固醇和提高的乳酸脱氢酶活性，而不增加血液尿素氮。大米蛋白质浓度可以制成湿面团，水分比大豆蛋白浓缩物少。大米蛋白浓缩物的使用从而改善了含有浓缩物的食品制剂的加工步骤。食品有利地显示出延长的保质期和改善的可口的质感。

3. 发明申请

WO2015048365A1 NOVEL 20(S)-SULFONYLAMIDINE DERIVATIVES OF CAMPTOTHECIN AND THE USE THEREOF AS A POTENT ANTITUMOR AGENT 审中-公开
标题翻译：氨茶碱的新二十（S） - 磺酰胺衍生物及其作为抗肿瘤剂的用途
公开(公告)号：WO2015048365A1
公开(公告)日：2015-04-02
申请号：PCT/US2014/057575
申请日：2014-09-26
申请人： LEE, Kuo-Hsiung , QIAN, Keduo , YANG, Xiaoming , GOTO, Masuo , LIU, Ying-Qian , ZHAO, Yong-Long , YANG, Liu , WANG, Mei-Juan , ZHANG, Zhi-Jun , WU, Tian-Shung , TENG, Che-Ming , WANG, Chih-Ya , PAN, Shiow-Lin , KUO, Sheng-Chu , HUNG, Hsin-Yi , CHANG, Ling-Chu , WU, Yang-Chang , HSIEH, Min-Tsang , HSU, Chung Y. , SHYU, Woei-Cherng , LIN, Chen-Huan
发明人： LEE, Kuo-Hsiung , QIAN, Keduo , YANG, Xiaoming , GOTO, Masuo , LIU, Ying-Qian , ZHAO, Yong-Long , YANG, Liu , WANG, Mei-Juan , ZHANG, Zhi-Jun , WU, Tian-Shung , TENG, Che-Ming , WANG, Chih-Ya , PAN, Shiow-Lin , KUO, Sheng-Chu , HUNG, Hsin-Yi , CHANG, Ling-Chu , WU, Yang-Chang , HSIEH, Min-Tsang , HSU, Chung Y. , SHYU, Woei-Cherng , LIN, Chen-Huan
IPC分类号： C07D491/12 , C07D471/04 , A61K31/4745 , A61K35/00
CPC分类号： C07D491/22 , C07F7/0812 , C07F9/6561
摘要： The present invention is related to novel 20-sulfonylamidine derivatives of camptothecin (1), method of synthesizing the same, and use thereof as an antitumor agent, for examples an antitumor agent for treating nasopharyngeal, lung, breast or prostate cancer.
摘要翻译：本发明涉及喜树碱（1）的新型20-磺酰脒衍生物，其合成方法及其作为抗肿瘤剂的用途，例如用于治疗鼻咽癌，肺癌，乳腺癌或前列腺癌的抗肿瘤剂。

4. 发明申请

US20130203140A1 PRODUCTION OF ISOPRENOIDS UNDER NEUTRAL pH CONDITIONS 有权
标题翻译：在中性pH条件下生产异烟肼
公开(公告)号：US20130203140A1
公开(公告)日：2013-08-08
申请号：US13566923
申请日：2012-08-03
申请人： Martien H. BERGSMA , Anthony R. Calabria , Gopal K. Chotani , William A. Cuevas , Gang Duan , Sung Ho Lee , Ying Qian , Vivek Sharma , Jayarama K. Shetty , Bruce A. Strohm , Paula Johanna Maria Teunissen , Hongxian Xu
发明人： Martien H. BERGSMA , Anthony R. Calabria , Gopal K. Chotani , William A. Cuevas , Gang Duan , Sung Ho Lee , Ying Qian , Vivek Sharma , Jayarama K. Shetty , Bruce A. Strohm , Paula Johanna Maria Teunissen , Hongxian Xu
IPC分类号： C12P5/00
CPC分类号： C12P5/007 , C12N9/1085 , C12N9/2428 , C12Y205/0101 , C12Y302/01003
摘要： Embodiments of the present disclosure relate to a process for producing isoprenoid precursor molecules and/or isoprenoids from a starch substrate by saccharification and/or fermentation. The saccharification is effectively catalyzed by a glucoamylase at a pH in the range of 5.0 to 8.0. At a pH of 6.0 or above, the glucoamylase possesses at least 50% activity relative to its maximum activity. The saccharification and fermentation may be performed as a simultaneous saccharification and fermentation (SSF) process.
摘要翻译：本公开的实施方案涉及通过糖化和/或发酵从淀粉底物生产类异戊二烯前体分子和/或类异戊二烯的方法。糖化在pH为5.0至8.0的范围内由葡糖淀粉酶有效地催化。在6.0或更高的pH下，葡糖淀粉酶相对于其最大活性具有至少50％的活性。糖化和发酵可以作为同时糖化和发酵（SSF）方法进行。

5. 发明授权

US08211823B2 Selective hydrogenation catalyst and the preparation thereof 有权
标题翻译：选择性氢化催化剂及其制备方法
公开(公告)号：US08211823B2
公开(公告)日：2012-07-03
申请号：US12747865
申请日：2008-10-22
申请人： Shunqin Liang , Limin Sun , Longgang Lv , Ying Qian , Yundi Zheng , Jie Wu , Tinghai Wang , Xiaoyan Li
发明人： Shunqin Liang , Limin Sun , Longgang Lv , Ying Qian , Yundi Zheng , Jie Wu , Tinghai Wang , Xiaoyan Li
IPC分类号： B01J23/00 , B01J21/00 , B01J20/00
CPC分类号： B01J23/63 , B01J21/04 , B01J23/002 , B01J35/008 , B01J35/1038 , B01J37/0205 , B01J37/0207 , B01J2523/00 , C10G45/40 , C10G2400/02 , B01J2523/24 , B01J2523/31 , B01J2523/3706 , B01J2523/824 , B01J2523/22 , B01J2523/3712 , B01J2523/25
摘要： A selective hydrogenation catalyst, with alumina as carrier, and palladium as active component that distributed on the surface of the carrier in an egg-shell form, characterized in that: provided that the catalyst is weighed 100%, it comprises 0.2-0.5 wt % active component Pd, 2-8 wt % aids lanthanum and/or cerium, and 2-8 wt % alkaline earth metal. The specific surface area of the catalyst is 70-150 m2/g, the pore volume is 0.3-0.6 ml/g, and the crystal form of the carrier may be θ form or θ, α mixed form mainly composed of θ form. The catalyst is suitable for the selective hydrogenation of medium or low distillate oil, especially for the first stage selective hydrogenation of pyrolysis gasoline. The catalyst has good hydrogenation performance, and can keep good hydrogenation activity and stability especially under the condition that the feed contains a small quantity of water, and the content of colloid, arsenic, and diolefin is higher.
摘要翻译：以氧化铝为载体的选择性氢化催化剂和以蛋壳形式分布在载体表面上的钯作为活性组分，其特征在于：如果催化剂称重为100％，则其包含0.2-0.5重量％活性组分Pd，2-8重量％有助于镧和/或铈，以及2-8重量％的碱土金属。催化剂的比表面积为70-150m2 / g，孔体积为0.3-0.6ml / g，载体的晶体形式可以是; 形式或主题;α混合形式主要由＆thetas组成; 形成。该催化剂适用于中等或低馏分油的选择性氢化，特别是热解汽油的第一阶段选择氢化。该催化剂具有良好的氢化性能，特别是在含有少量水的条件下，可保持良好的氢化活性和稳定性，胶体，砷和二烯含量较高。

6. 发明申请

US20120034659A1 NEUTRAL pH SACCHARIFICATION AND FERMENTATION 审中-公开
标题翻译：中性pH浓度和发酵
公开(公告)号：US20120034659A1
公开(公告)日：2012-02-09
申请号：US13204561
申请日：2011-08-05
申请人： Martien H. Bergsma , Gopal K. Chotani , William A. Cuevas , Gang Duan , Sung Ho Lee , Ying Qian , Vivek Sharma , Jayarama K. Shetty , Bruce A. Strohm , Paula Johanna Maria Teunissen , Hongxian Xu
发明人： Martien H. Bergsma , Gopal K. Chotani , William A. Cuevas , Gang Duan , Sung Ho Lee , Ying Qian , Vivek Sharma , Jayarama K. Shetty , Bruce A. Strohm , Paula Johanna Maria Teunissen , Hongxian Xu
IPC分类号： C12P19/20 , C12P7/04 , C12P7/16 , C12P7/56 , C12P7/46 , C12P7/18 , C12P13/04 , C12P7/14 , C12P13/14
CPC分类号： C12P7/06 , C12P7/04 , C12P7/14 , C12P7/16 , C12P7/18 , C12P7/46 , C12P7/56 , C12P13/04 , C12P13/14 , C12P19/20 , Y02E50/10 , Y02E50/17
摘要： Embodiments of the present disclosure relate to a process for producing downstream products, such as fermentable sugars and end products, from a starch substrate by saccharification and/or fermentation. The saccharification is effectively catalyzed by a glucoamylase at a pH in the range of 5.0 to 8.0. At a pH of 6.0 or above, the glucoamylase possesses at least 50% activity relative to its maximum activity. The saccharification and fermentation may be performed as a simultaneous saccharification and fermentation (SSF) process.
摘要翻译：本公开的实施方案涉及通过糖化和/或发酵从淀粉底物生产下游产物如可发酵糖和终产物的方法。糖化在pH为5.0至8.0的范围内由葡糖淀粉酶有效地催化。在6.0或更高的pH下，葡糖淀粉酶相对于其最大活性具有至少50％的活性。糖化和发酵可以作为同时糖化和发酵（SSF）方法进行。

7. 发明授权

US5966966A Process and system for freeze concentration using ultrasonic nucleation useful in effluent processing 失效
标题翻译：使用超声波成核的冷冻浓缩过程和系统可用于废水处理
公开(公告)号：US5966966A
公开(公告)日：1999-10-19
申请号：US82169
申请日：1998-05-20
申请人： Gregory D. Botsaris , Ru-Ying Qian
发明人： Gregory D. Botsaris , Ru-Ying Qian
IPC分类号： B01D9/00 , B01D9/04
CPC分类号： B01D9/0013
摘要： A freeze concentration method separates the nucleation and the growth processes at least to the extent necessary to enable nucleation and crystal growth to occur at different temperatures. Nucleation, however, is triggered by a sonicator, i.e., ultrasonic radiation. This provides excellent control of the process since the variables of the input sonic energy are adjusted easily. Most importantly, the use of ultrasound permits nucleation at low supercooling. The consequences of this are: an inexpensive plain--as opposed to the more complex and expensive scraped-surface--heat exchanger can be used since the coolant temperature is only slightly lower than that of the solution, preventing ice scaling in the heat exchanger; the higher coolant temperature leads to savings also in the operation costs. In addition ultrasonic nucleators are easily scaled-up to treating the large-volume effluents from industrial plants. The only way to scale-up scraped-surface nucleators is by using multiple nucleators in parallel.
摘要翻译：冷冻浓缩法将成核和生长过程至少分离成使得成核和晶体生长在不同温度下发生所必需的程度。然而，成核由超声波器即超声波辐射触发。由于输入声波能量的变量容易调整，因此可以很好地控制过程。最重要的是，使用超声波可以在低过冷度下成核。其结果是：廉价的平面 - 与更复杂和更昂贵的刮表面热交换器相反，因为冷却剂温度仅略低于溶液的温度，防止热交换器中的冰结垢; 较高的冷却液温度也可以节省运营成本。此外，超声波成核剂容易扩大到处理来自工厂的大容积流出物。刮除表面成核剂的唯一方法是平行使用多个成核剂。

8. 发明授权

US08817723B2 Methods and apparatus for inter-cell interference coordination self-organized network 有权
标题翻译：细胞间干扰协调自组织网络的方法和装置
公开(公告)号：US08817723B2
公开(公告)日：2014-08-26
申请号：US13298893
申请日：2011-11-17
申请人： Mohammadhadi Baligh , Ying Qian
发明人： Mohammadhadi Baligh , Ying Qian
IPC分类号： H04W4/00 , H04W72/00
CPC分类号： H04W24/02 , H04W16/10 , H04W24/08
摘要： A method of resource allocation for use in a wireless network is disclosed. A network coloring decision to assign a plurality of resource blocks to a plurality of cells within the wireless network is triggered upon occurrence of a network event. A network coloring is performed by assigning each cell of the plurality of cells a resource block from the plurality of resource blocks. An effect of interference among adjacent cells with a same resource block assignment is reduced as measured by a network performance metric related to a number of resource block assignment conflicts over the plurality of cells.
摘要翻译：公开了一种在无线网络中使用的资源分配方法。在发生网络事件时，触发对无线网络内的多个小区分配多个资源块的网络着色决定。通过从多个资源块分配多个小区的资源块来执行网络着色。通过与多个小区上的资源块分配冲突的数量有关的网络性能度量来测量相同资源块分配的相邻小区之间的干扰的影响。

9. 发明申请

US20120301927A1 Production Of Maltotetraose Syrup Using A Pseudomonas Saccharophila Maltotetraohydrolase Variant 审中-公开
标题翻译：使用糖酵母假单胞菌Maltotetraohydrolase变体生产麦芽四糖糖浆
公开(公告)号：US20120301927A1
公开(公告)日：2012-11-29
申请号：US13263419
申请日：2010-04-08
申请人： Gang Duan , Sung Ho Lee , Ying Qian , Rafael F. Sala , Jayarama Shetty
发明人： Gang Duan , Sung Ho Lee , Ying Qian , Rafael F. Sala , Jayarama Shetty
IPC分类号： C12N9/28 , C12N15/63 , C12P19/14 , D06M16/00 , C12N1/19 , C12P7/14 , C12P19/16 , C12N15/56 , C12N1/21
CPC分类号： C12P19/14 , C12N9/2417 , C12P7/10 , C12P7/14 , C12P19/16 , D06L1/14 , D06M16/003 , Y02E50/16
摘要： Variants of a Pseudomonas saccharophila G4-forming amylase (PS4) advantageously can catalyze high temperature saccharification to produce maltotetraose syrup from a starch liquefact or granular starch, e.g., derived from cornstarch. The PS4 variants are useful in a process of saccharification of starch that advantageously produces significant amounts of maltotetraose, which can be used downstream in a process of producing a maltotetraose syrup. In one embodiment, a thermostable PS4 variant is provided that can produce about 40% to about 60% by weight maltotetraose, based on total saccharide content.
摘要翻译：酿酒酵母G4形成淀粉酶（PS4）的变体有利地可以催化高温糖化以从淀粉液化或颗粒淀粉（例如衍生自玉米淀粉）产生麦芽四糖糖浆。 PS4变体可用于淀粉糖化过程，其有利地产生显着量的麦芽四糖，其可以在生产麦芽四糖糖浆的方法中在下游使用。在一个实施方案中，提供了基于总糖含量可产生约40重量％至约60重量％麦芽四糖的耐热性PS4变体。

10. 发明申请

US20120135466A1 Production Of Maltotetraose Syrup Using A Pseudomonas Saccharophila Maltotetraohydrolase Variant And A Debranching Enzyme 审中-公开
标题翻译：使用糖酵母假单胞菌麦芽四氢水解酶变体和脱支酶生产麦芽四糖糖浆
公开(公告)号：US20120135466A1
公开(公告)日：2012-05-31
申请号：US13263606
申请日：2010-04-08
申请人： Gang Duan , Ying Qian , Rafael F. Sala , Jayarama Shetty
发明人： Gang Duan , Ying Qian , Rafael F. Sala , Jayarama Shetty
IPC分类号： C12P19/00
CPC分类号： C12P19/14
摘要： The combination of a Pseudomonas saccharophila G4-forming amylase (PS4) variant and a pullulanase advantageously can catalyze at a high temperature saccharification to produce an increased amount of maltotetraose, which can be used downstream in a process of producing a maltotetraose syrup. In one embodiment, a thermostable PS4 variant supplement with a pullulanase is provided that can produce about 40% to about 60% by weight maltotetraose, based on total saccharide content.
摘要翻译：酿酒酵母G4形成淀粉酶（PS4）变体和支链淀粉酶的组合有利地可以在高温糖化下催化产生增加量的麦芽四糖，其可以在生产麦芽四糖糖浆的方法中用于下游。在一个实施方案中，提供了具有支链淀粉酶的热稳定性PS4变体，其可以基于总糖含量产生约40重量％至约60重量％的麦芽四糖。

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