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1. 发明申请

US20100095986A1 METHOD OF CLEANING MICRO-FLOW PASSAGES 审中-公开
标题翻译：清洁微流通道的方法
公开(公告)号：US20100095986A1
公开(公告)日：2010-04-22
申请号：US12593860
申请日：2008-03-28
申请人： Yoshihiro Seto , Luc Bousse , Chen Li
发明人： Yoshihiro Seto , Luc Bousse , Chen Li
IPC分类号： B08B9/032 , B08B9/035
CPC分类号： B08B9/0321 , B08B9/035
摘要： To improve cleansing quality of wall surfaces of micro-flow channels in a micro-flow channel cleansing method. During cleansing of wall surfaces of micro-flow channels having at least one branching channel, by causing cleansing fluid to flow therethrough, the cleansing fluid is caused to flow through the at least one branching channel such that there is no residual fluid on the wall surfaces thereof.
摘要翻译：以微流通道清洗方式提高微流通道壁表面的清洁质量。在清洁具有至少一个分支通道的微流动通道的壁表面之间，通过使清洁流体流过其中，使净化流体流过至少一个分支通道，使得在壁表面上不存在残留流体其中。

2. 发明授权

US07429356B2 Extracting apparatus 有权
标题翻译：提取设备
公开(公告)号：US07429356B2
公开(公告)日：2008-09-30
申请号：US10920447
申请日：2004-08-18
申请人： Yoshihiro Seto , Takahiro Miyato , Keiichi Fujimoto
发明人： Yoshihiro Seto , Takahiro Miyato , Keiichi Fujimoto
IPC分类号： G01N35/10
CPC分类号： B01L3/50255 , B01L9/06 , B01L2400/0487 , G01N1/405 , G01N35/026
摘要： A loading mechanism holds at least one extracting cartridge provided with a filter member, at least one waste liquid vessel for accommodating a discharged liquid of a sample liquid and a discharged liquid of a washing liquid, which discharged liquids have been discharged from the extracting cartridge, and at least one recovery vessel for accommodating a recovery liquid, which contains a recovered nucleic acid and has been discharged from the extracting cartridge. A pressurized air supplying mechanism introduces pressurized air into the extracting cartridge. A liquid injecting mechanism injects each of the washing liquid and the recovery liquid into the extracting cartridge.
摘要翻译：装载机构保持至少一个提供有过滤构件的提取筒，至少一个用于容纳样品液体的排出液体和排出液体已经从提取筒排出的洗涤液的排出液体的废液容器，以及至少一个用于容纳回收液体的回收容器，所述回收液体含有回收的核酸并已从提取筒中排出。加压空气供给机构将加压空气引入提取筒。液体注入机构将每个洗涤液和回收液注入提取筒。

3. 发明申请

US20070041868A1 Biochemical analysis method and apparatus 失效
公开(公告)号：US20070041868A1
公开(公告)日：2007-02-22
申请号：US11588292
申请日：2006-10-27
申请人： Yoshihiro Seto , Nobuaki Tokiwa , Yoichi Endo
发明人： Yoshihiro Seto , Nobuaki Tokiwa , Yoichi Endo
IPC分类号： G01N31/22
CPC分类号： G01N35/1011 , G01N2035/00118 , G01N2035/0446 , Y10T436/112499 , Y10T436/114165
摘要： Samples and dry chemical analysis elements, which are necessary for analyses of the samples, are loaded on a sample tray. Each sample is sucked with a spotting nozzle of a spotting unit and spotted onto one dry chemical analysis element. Analysis information, which contains information representing a type of analysis, is appended to each dry chemical analysis element. The analysis information is read with a reading device located such that, when a certain sample is located at a position for sample suction by an operation of the sample tray, the reading device reads the analysis information, which has been appended to a next dry chemical analysis element to be used for the analysis of the certain sample, at a position at which the next dry chemical analysis element is located.

4. 发明授权

US06713018B2 Dry chemical analysis element cartridge 失效
标题翻译：干化学分析盒
公开(公告)号：US06713018B2
公开(公告)日：2004-03-30
申请号：US09836537
申请日：2001-04-18
申请人： Fumio Sugaya , Yoichi Endo , Nobuaki Tokiwa , Akihiro Komatsu , Yoshihiro Seto
发明人： Fumio Sugaya , Yoichi Endo , Nobuaki Tokiwa , Akihiro Komatsu , Yoshihiro Seto
IPC分类号： G01N3122
CPC分类号： G01N33/48757 , G01N35/00029 , G01N2035/00059 , G01N2035/00089
摘要： A dry chemical analysis element cartridge includes a box-like cartridge casing in which a plurality of chemical analysis elements are stacked and are taken out through an element take-out port formed at one end of the cartridge casing. The inner dimension of the cartridge casing in the direction of the stack of the chemical analysis elements is smaller than the longitudinal and transverse dimensions of each of the chemical analysis elements.
摘要翻译：干化学分析元件盒包括盒状盒壳体，其中堆叠多个化学分析元件，并且通过形成在盒壳体一端的元件取出口取出。药筒外壳在化学分析元件的堆叠方向上的内部尺寸小于每个化学分析元件的纵向和横向尺寸。

5. 发明授权

US06642058B2 Analysis method using dry chemical analysis element 失效
标题翻译：使用干化学分析元素的分析方法
公开(公告)号：US06642058B2
公开(公告)日：2003-11-04
申请号：US09853751
申请日：2001-05-14
申请人： Fumio Sugaya , Yoichi Endo , Nobuaki Tokiwa , Akihiro Komatsu , Yoshihiro Seto
发明人： Fumio Sugaya , Yoichi Endo , Nobuaki Tokiwa , Akihiro Komatsu , Yoshihiro Seto
IPC分类号： G01N3348
CPC分类号： G01N21/5907
摘要： An analysis method using a dry chemical analysis element accurately measures change in optical density indicating the composition of a liquid sample without requiring accurate control of the amount and position of the liquid sample dripped on the dry chemical analysis element. A one-dimensional or two-dimensional optical reading apparatus measures one-dimensional or two-dimensional distribution of degree of color reaction for a reacted portion of the dry chemical analysis element. Concurrently, the one-dimensional or two-dimensional optical reading apparatus measures a length or a spread area of the reacted portion. Physical density or activity of a target component contained in the liquid sample is determined based on an integrated value of the degree of the color reaction and the measured length or the spread area of the reacted portion.
摘要翻译：使用干化学分析元件的分析方法精确地测量表示液体样品组成的光密度变化，而不需要精确控制滴在干化学分析元件上的液体样品的量和位置。一维或二维光学读取装置测量干化学分析元件的反应部分的显色反应程度的一维或二维分布。同时，一维或二维光学读取装置测量反应部分的长度或扩展面积。基于颜色反应程度和反应部分的测量长度或扩展面积的积分值来确定液体样品中包含的目标组分的物理密度或活性。

6. 发明授权

US5731207A Transferring method and device for dry chemical analysis film 失效
标题翻译：干化学分析膜的转移方法和装置
公开(公告)号：US5731207A
公开(公告)日：1998-03-24
申请号：US698162
申请日：1996-08-07
申请人： Yoshihiro Seto
发明人： Yoshihiro Seto
IPC分类号： G01N31/22 , B65H5/08 , B65H5/16 , G01N35/00 , G01N35/04 , G01N35/10
CPC分类号： G01N35/00029 , G01N2035/00059 , G01N2035/00089 , Y10S436/807 , Y10T436/110833 , Y10T436/112499 , Y10T436/115831
摘要： A frameless chemical analysis film includes a reagent layer formed on a support sheet. When the frameless chemical analysis film which has been held on a resilient suction pad under a suction force supplied to the suction pad is transferred to a predetermined member, the suction force supplied to the suction pad is gradually released taking at least a time which the suction pad, which has been deformed under the suction force, takes to be restored to the original shape.
摘要翻译：无框化学分析膜包括形成在支撑片上的试剂层。当被提供给吸盘的抽吸力被保持在弹性吸盘上的无框架的化学分析膜被转移到预定的构件时，至少吸入吸力的吸力被缓慢地释放，在吸力作用下变形的垫片恢复原来的形状。

7. 发明授权

US5617973A Cartridge for dry-type chemical analysis films 失效
标题翻译：干式化学分析胶片盒
公开(公告)号：US5617973A
公开(公告)日：1997-04-08
申请号：US405808
申请日：1995-03-16
申请人： Yoshihiro Seto , Fumio Sugaya
发明人： Yoshihiro Seto , Fumio Sugaya
IPC分类号： G01N31/22 , A61B10/00 , G01N1/28 , G01N35/00 , B65H1/08
CPC分类号： G01N35/00029 , A61B5/150358 , A61B10/007 , A61B5/150015 , G01N2035/00089 , G01N2035/00108
摘要： A cartridge for dry-type chemical analysis films comprises a box housing, which accommodates therein a stack of dry-type chemical analysis films and which has a take-out opening at one end such that the dry-type chemical analysis films may be taken out of the box housing through the take-out opening one after another. A push member is located in the box housing so as to be capable of sliding. The push member comes into contact with the stack of the dry-type chemical analysis films from the side opposite to the take-out opening and pushes the stack of the dry-type chemical analysis films in the direction heading towards the take-out opening. An urging member is located in the box housing and urges the push member in the direction heading towards the take-out opening. A restriction member is located in the box housing and restricts the distance of movement of the push member in the direction heading away from the take-out opening to at most a value equal to the width of each dry-type chemical analysis film.
摘要翻译：用于干式化学分析膜的盒包括盒壳体，其容纳有干式化学分析膜的堆叠，并且其一端具有取出开口，使得可以取出干式化学分析膜的箱子通过出口开口一个接一个。推动构件位于箱体中以便能够滑动。推动构件从与取出开口相对的一侧与干式化学分析膜的堆叠接触，并且在朝向取出开口的方向上推动干式化学分析膜的堆叠。推动构件位于箱体中并沿着朝向取出开口的方向推动推动构件。限制构件位于盒体中，并且限制推动构件在远离取出开口的方向上的移动距离至多等于每个干式化学分析膜的宽度的值。

8. 发明申请

US20100108514A1 METHOD OF CONTROLLING TEMPERATURE 审中-公开
标题翻译：控制温度的方法
公开(公告)号：US20100108514A1
公开(公告)日：2010-05-06
申请号：US12593875
申请日：2008-03-28
申请人： Yoshihiro Seto , Tomohisa Kawabata , Chungsoo Charles Park
发明人： Yoshihiro Seto , Tomohisa Kawabata , Chungsoo Charles Park
IPC分类号： G01N27/26
CPC分类号： G01N27/44708
摘要： To suppress temperature variations of sample fluids within flow channels for electrophoresis, in a method for controlling temperatures within micro flow channels. When controlling the temperatures of sample fluids within micro flow channels of electrophoresis chips, in which flow channels through which electrophoresis occurs by application of electrical potential differences can be switched, temperature variations of the sample fluids within the micro flow channels, caused by differences in heat generated by the sample fluids prior to and following the switching of the flow channels, are predicted. Control properties for temperature control in order to cancel the temperature variations are changed during the switching of the flow channels.
摘要翻译：为了抑制用于电泳的流动通道内的样品流体的温度变化，用于控制微流动通道内的温度的方法。当控制电泳芯片的微流通道内的样品流体的温度，其中可以切换通过施加电势差而发生电泳的流动通道时，由微热流通道中的热差导致的样品流体的温度变化预测在流动通道切换之前和之后由样品流体产生的。为了消除温度变化，温度控制的控制特性在流道切换期间发生变化。

9. 发明授权

US07285245B2 Biochemical analysis method and apparatus 有权
标题翻译：生化分析方法及仪器
公开(公告)号：US07285245B2
公开(公告)日：2007-10-23
申请号：US10233554
申请日：2002-09-04
申请人： Yoshihiro Seto
发明人： Yoshihiro Seto
IPC分类号： G01N21/00
CPC分类号： G01N35/00029 , G01N2035/00049 , Y10T436/11 , Y10T436/112499 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： Samples and dry chemical analysis elements necessary for analyses of the samples are loaded on a circular sampler tray. Each of the samples having been loaded on the sampler tray is sucked through a spotting nozzle and spotted onto one of the dry chemical analysis elements. A temperature of each of the dry chemical analysis elements having been spotted with the samples is kept at a constant temperature in an incubator. The sampler tray is provided with a circular rotating disk. Sample vessels, each of which accommodates one of the samples, the dry chemical analysis elements of kinds corresponding to types of the analyses of the samples, nozzle tips, each of which is to be fitted to the spotting nozzle, diluent liquid vessels accommodating a diluent liquid, and mixing cups for dilution are supported on the rotating disk.
摘要翻译：将样品分析所需的样品和干化学分析元素装载在圆形取样器托盘上。已经装载在采样器托盘上的每个样品通过点样喷嘴吸入并且被点到其中一个干化学分析元件上。已经将样品点样的每个干化学分析元件的温度在培养箱中保持恒定温度。取样器托盘设有圆形旋转盘。样品容器，每个样品容纳一个样品，对应于样品分析类型的干燥化学分析元素，每个要装配到点样喷嘴的喷嘴尖端，容纳稀释剂的稀释液体容器液体和用于稀释的混合杯支撑在旋转盘上。

10. 发明申请

US20050042146A1 Rack for extracting apparatuses 审中-公开
标题翻译：用于提取设备的机架
公开(公告)号：US20050042146A1
公开(公告)日：2005-02-24
申请号：US10920441
申请日：2004-08-18
申请人： Yoshihiro Seto
发明人： Yoshihiro Seto
IPC分类号： B01L3/00 , B01L9/06 , G01N1/34 , G01N1/40 , B01L9/00
CPC分类号： G01N1/34 , B01L3/50255 , B01L9/06 , B01L2200/0631 , B01L2200/141 , G01N1/405
摘要： A rack holds, in a state of a set, an extracting cartridge, a waste liquid vessel for accommodating discharged liquids of a sample liquid and a washing liquid having been discharged from the extracting cartridge, and a recovery vessel for accommodating a recovery liquid, which contains a recovered predetermined substance and has been discharged from the extracting cartridge. The extracting cartridge is held at a top section of the rack. The waste liquid vessel and the recovery vessel are held at positions below the top section of the rack, such that the waste liquid vessel and the recovery vessel are capable of being moved alternately to the position just below the extracting cartridge having been held at the top section of the rack.
摘要翻译：一种架子以一组状态保持提取筒，用于容纳样品液体的排出液体和从提取筒排出的洗涤液的废液容器和用于容纳回收液体的回收容器，其中含有回收的预定物质并已从提取筒排出。提取盒被保持在机架的顶部。废液容器和回收容器被保持在机架的顶部下方的位置处，使得废液容器和回收容器能够交替移动到刚被保持在顶部的提取筒的正下方的位置机架部分。

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