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1. 发明专利

IL177244D0 ASTAXANTHIN, ESTERS THEREOF AND COMPOSITIONS CONTAINING THEM, FOR REGULATING GENE EXPRESSION, AND THEIR USE IN THE MANUFACTURE OF MEDICAMENTS 未知
公开(公告)号：IL177244D0
公开(公告)日：2006-12-10
申请号：IL17724406
申请日：2006-08-02
申请人： FUJI CHEM IND CO LTD , YUJI NAITO , TAKAHASHI JIRO , AOI WATARU , NAITO YUJI
IPC分类号： A23L20100101 , A23L1/30 , A61K31/122 , A61K31/21 , A61P1/04 , A61P1/18 , A61P3/06 , A61P3/10 , A61P9/10 , A61P9/12 , A61P11/00 , A61P13/12 , A61P25/02 , A61P25/28 , A61P27/02 , A61P27/12 , A61P29/00 , A61P35/00 , A61P37/08 , A61P43/00
摘要： To provide a gene expression regulating agent which includes astaxanthin and/or its ester as an effective ingredient; and a food and drink having an effect of regulating gene expression which includes astaxanthin and/or its ester. Abnormal gene expression due to, for example, oxidative stress can be treated, improved, and/or prevented, and diseases caused by the abnormal gene expression can be treated, improved, and/or prevented. A gene expression regulating agent which includes astaxanthin and/or its ester as an effective ingredient; and a food and drink having an effect of regulating gene expression which includes astaxanthin and/or its ester are provided and are useful for treating, improving, and/or preventing the symptom caused by the abnormal gene expression, that is, excessive expression or suppression of expression.

2. 发明专利

JP2006213667A Muscular atrophy-improving agent containing astaxanthin and/or its ester as active ingredient and food or drink 有权
标题翻译：含有ASTAXANTHIN和/或其作为活性成分和食物或饮料的肌肉ATROPHY改进剂
公开(公告)号：JP2006213667A
公开(公告)日：2006-08-17
申请号：JP2005029487
申请日：2005-02-04
申请人： Fuji Chem Ind Co Ltd , Yuji Naito , 裕二内藤 , 富士化学工業株式会社
发明人： NAITO YUJI , AOI WATARU , TAKAHASHI JIRO
IPC分类号： A61K31/122 , A23L1/30 , A61P21/00 , A61P21/04
摘要： PROBLEM TO BE SOLVED: To provide a medicine for improving, treating and preventing muscular atrophy lesions caused by nervous disorders, long period immobilization, senility, or the like, to provide a medicine for improving, treating and preventing diseases caused by the muscular atrophy lesions, and to provide a food or drink having effects for improving, treating and preventing the muscular atrophy lesions.
SOLUTION: Astaxanthin having widely used as a pigment and having been noted to have high anti-oxidizing ability is provided as an agent for improving muscular atrophy lesions. Thereby, provided can be an agent for improving, treating and preventing the muscular atrophy lesions, containing the astaxanthin as an active ingredient, and a food or drink having effects for improving, treating and preventing the muscular atrophy lesions, containing the astaxanthin as an active ingredient.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：待解决的问题：提供用于改善，治疗和预防由神经障碍，长期固定化，衰老等引起的肌肉萎缩性病变的药物，以提供用于改善，治疗和预防由肌肉萎缩病变，并提供具有改善，治疗和预防肌肉萎缩性病变的作用的食物或饮料。提供广泛用作颜料并被注意到具有高抗氧化能力的虾青素作为改善肌肉萎缩性病变的药剂。因此，可以提供含有虾青素作为活性成分的肌肉萎缩病变的改善，治疗和预防剂，以及具有改善，治疗和预防含有虾青素作为活性物质的肌肉萎缩病变的作用的食品或饮料成分。版权所有（C）2006，JPO＆NCIPI

3. 发明专利

JP2012231752A Genetic biomarker predicting stability of blood concentration of azathioprine(azt) in patient with inflammatory intestine disease 有权
标题翻译：遗传生物标志物预测AZATHIOPRINE（AZT）在患有炎症性肠病的患者中血液浓度的稳定性
公开(公告)号：JP2012231752A
公开(公告)日：2012-11-29
申请号：JP2011103133
申请日：2011-05-02
申请人： Haplo Pharma:Kk , 株式会社ハプロファーマ , Yuji Naito , 裕二内藤 , Kazuhiko Uchiyama , 和彦内山
发明人： NAITO YUJI , UCHIYAMA KAZUHIKO , NEMOTO YASUHISA
IPC分类号： C12N15/09 , C12Q1/68
摘要： PROBLEM TO BE SOLVED: To provide a genetic biomarker involved in such a phenotype that the blood concentration of the medicament's metabolite is kept high when azathioprine is administered.SOLUTION: A method for predicting the stability of the blood concentration of azathioprine in a subject administered therewith is provided, comprising: detecting in vitro a genetic polymorphism enabling the determination of the difference among expression levels in 15 kinds of genes with differences occurring in the subject administered with azathioprine.
摘要翻译：要解决的问题：提供涉及这种表型的遗传生物标志物，当施用硫唑嘌呤时，药物代谢物的血液浓度保持较高。提供了一种用于预测施用对象的受试者中硫唑嘌呤血药浓度稳定性的方法，其包括：体外检测遗传多态性，从而能够测定出现差异的15种基因中的表达水平之间的差异在服用硫唑嘌呤的受试者中。版权所有（C）2013，JPO＆INPIT

4. 发明专利

JP2006212167A Golf swing practice aid 审中-公开
标题翻译：高尔夫挥杆练习
公开(公告)号：JP2006212167A
公开(公告)日：2006-08-17
申请号：JP2005027262
申请日：2005-02-03
申请人： Yuji Naito , Yamani:Kk , 雄士内藤 , 株式会社ヤマニ
发明人： NAITO YUJI , NISHI KAZUTOSHI
IPC分类号： A63B69/36
CPC分类号： A63B69/3608 , A63B69/0059 , A63B2209/10
摘要： PROBLEM TO BE SOLVED: To improve a swing practice effect by reducing a gap between a case of wearing a swing practice device and non-wearing it as much as possible. SOLUTION: This golf swing practice aid 1 comprises an interval retaining body 10 closely interposed between the both wrists or the front arm parts in a triangle formed between the both shoulders and the grip in a golf swing, and a band 20 provided in the interval retaining body 10 and attaching the interval retaining body 10 to one wrist or one front arm part. The abutment parts of the interval retaining body 10 on the both wrists or the both front arm parts are formed with recessed parts 12L and 12R along the curved faces of the both wrists or the both front arms. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：通过减少穿着摆动练习装置的情况和尽可能不佩戴之间的间隙来改善摆动练习效果。解决方案：该高尔夫挥杆练习辅助装置1包括间隔保持体10，该间隔保持体10紧密地插入在两个手腕或前臂部件之间，三角形形成在两个肩部和高尔夫挥杆中的把手之间，并且带20设置在间隔保持体10并且将间隔保持体10附接到一个手腕或一个前臂部。两个腕部或两个前臂部分上的间隔保持体10的邻接部分沿着两个手腕或两个前臂的弯曲面形成有凹陷部分12L和12R。版权所有（C）2006，JPO＆NCIPI

5. 发明申请

US20110124212A1 Card Connector 有权
标题翻译：卡连接器
公开(公告)号：US20110124212A1
公开(公告)日：2011-05-26
申请号：US12989548
申请日：2009-04-23
申请人： Yuji Naito , Mitsuhiro Tomita , Yoko Takeuchi
发明人： Yuji Naito , Mitsuhiro Tomita , Yoko Takeuchi
IPC分类号： H01R13/62
CPC分类号： H01R13/635 , G06K7/0021
摘要： A card connector comprises a housing, an auxiliary urging member and a card guide mechanism. The housing is provided with connection terminals connected to a card housed therein. The auxiliary urging member is capable of urging the card in a direction opposite to an insertion direction of the card. The card guide mechanism is provided with an urging member capable of urging the card in the direction opposite to the insertion direction of the card. The urging member and the auxiliary urging member are also configured to cooperate with each other to move the card.
摘要翻译：卡连接器包括壳体，辅助推动构件和卡引导机构。壳体设置有连接到容纳在其中的卡的连接端子。辅助推动构件能够沿与卡的插入方向相反的方向推动卡。卡引导机构设置有能够沿与卡的插入方向相反的方向推动卡的推动构件。推动构件和辅助推动构件也构造成彼此协作以移动卡。

6. 外观设计

USD599802S1 Memory-card attachment 有权
标题翻译：存储卡附件
公开(公告)号：USD599802S1
公开(公告)日：2009-09-08
申请号：US29302781
申请日：2008-01-24
申请人： Yasuyoshi Matsumoto , Mitsuhiro Tomita , Yuichi Hasegawa , Yuji Naito , Yoko Takeuchi , Hideaki Matsuoto , Kazuya Igarashi
设计人： Yasuyoshi Matsumoto , Mitsuhiro Tomita , Yuichi Hasegawa , Yuji Naito , Yoko Takeuchi , Hideaki Matsuoto , Kazuya Igarashi

7. 发明申请

US20090156657A1 ANTI-INFLAMMATORY COMPOSITION 有权
标题翻译：抗炎组合物
公开(公告)号：US20090156657A1
公开(公告)日：2009-06-18
申请号：US12267907
申请日：2008-11-10
申请人： Yuji Naito , Naoto Koyama , Katsuya Suzuki , Hideaki Kihara , Yuka Ikenoue
发明人： Yuji Naito , Naoto Koyama , Katsuya Suzuki , Hideaki Kihara , Yuka Ikenoue
IPC分类号： A61K31/405
CPC分类号： A61K31/4045 , A23L33/105 , A61K36/286
摘要： The present invention provides a method of improving or preventing various conditions through suppression of the expression of inflammatory cytokines based on the action mechanism of suppression of NF-κB activation. The present invention provides a composition for suppressing NF-κB activation, containing a serotonin derivative such as feruloyl serotonin (N-feruloyl serotonin) and p-coumaroyl serotonin (N-(p-coumaroyl)serotonin), a composition for suppressing the expression of VCAM-1 and/or MCP-1 via NF-κB, containing the serotonin derivative and an anti-inflammatory composition containing the serotonin derivative. The composition of the present invention can be used as a pharmaceutical agent or a food.
摘要翻译：本发明提供了通过抑制NF-κB活化的作用机制来抑制炎性细胞因子的表达来改善或预防各种病症的方法。本发明提供一种抑制NF-κB活化的组合物，其中含有血清素衍生物如阿魏酰5-羟色胺（N-阿魏酰5-羟色胺）和对 - 香豆酰5-羟色胺（N-（对 - 香豆酰基）5-羟色胺），用于抑制含有5-羟色胺衍生物的NF-κB的VCAM-1和/或MCP-1以及含有5-羟色胺衍生物的抗炎组合物。本发明的组合物可以用作药剂或食品。

8. 发明授权

US08632350B2 Card connector 有权
标题翻译：卡连接器
公开(公告)号：US08632350B2
公开(公告)日：2014-01-21
申请号：US13542954
申请日：2012-07-06
申请人： Ryo Uesaka , Masamitsu Takasaki , Yuji Naito , Mitsuhiro Tomita
发明人： Ryo Uesaka , Masamitsu Takasaki , Yuji Naito , Mitsuhiro Tomita
IPC分类号： H01R13/62
CPC分类号： G06K13/0825
摘要： A slide member includes a side edge holding part, which extends towards the front end edge of the housing, and a front end holding part, which is connected to the front end of the side edge holding part and extends in the transverse direction of the housing. The slide member is able to slide forward and backward along one side edge of the bottom wall part of the housing. The housing contains a mistaken insertion prevention convex part which the front end or rear end of a mistakenly inserted card contacts.
摘要翻译：滑动构件包括朝向壳体的前端边缘延伸的侧边缘保持部分，以及前端保持部分，其连接到侧边缘保持部分的前端并沿着壳体的横向方向延伸。滑动构件能够沿着壳体的底壁部分的一个侧边缘向前和向后滑动。壳体包含错误插入卡片的前端或后端接触的错误插入防止凸部。

9. 外观设计

USD604738S1 Memory-card attachment 有权
公开(公告)号：USD604738S1
公开(公告)日：2009-11-24
申请号：US29302759
申请日：2008-01-24
申请人： Yasuyoshi Matsumoto , Mitsuhiro Tomita , Yuichi Hasegawa , Yuji Naito , Yoko Takeuchi , Hideaki Matsuoto , Kazuya Igarashi
设计人： Yasuyoshi Matsumoto , Mitsuhiro Tomita , Yuichi Hasegawa , Yuji Naito , Yoko Takeuchi , Hideaki Matsuoto , Kazuya Igarashi

10. 发明申请

US20080269349A1 Gene expression regulating agent 审中-公开
标题翻译：基因表达调控剂
公开(公告)号：US20080269349A1
公开(公告)日：2008-10-30
申请号：US12155914
申请日：2008-06-11
申请人： Yuji Naito , Jiro Takahashi , Wataru Aoi
发明人： Yuji Naito , Jiro Takahashi , Wataru Aoi
IPC分类号： A61K31/122 , A61P3/10
CPC分类号： A61K31/122 , A23L2/52 , A23L33/10 , A23L33/105 , A23V2002/00 , A61K31/21
摘要： An object of the invention is to provide a gene expression regulating agent which includes astaxanthin and/or its ester as an effective ingredient; and a food and drink having an effect of regulating gene expression which includes astaxanthin and/or its ester. Abnormal gene expression due to, for example, oxidative stress can be treated, improved, and/or prevented, and diseases caused by the abnormal gene expression can be treated, improved, and/or prevented. A gene expression regulating agent which includes astaxanthin and/or its ester as an effective ingredient; and a food and drink having an effect of regulating gene expression which includes astaxanthin and/or its ester are provided and are useful for treating, improving, and/or preventing the symptom caused by the abnormal gene expression, that is, excessive expression or suppression of expression.
摘要翻译：本发明的目的是提供一种包含虾青素和/或其酯作为有效成分的基因表达调节剂; 以及具有调节基因表达的作用的食品和饮料，其包括虾青素和/或其酯。可以治疗，改善和/或预防由于例如氧化应激引起的异常基因表达，并且可以治疗，改善和/或预防由异常基因表达引起的疾病。包含虾青素和/或其酯作为有效成分的基因表达调节剂; 并且提供具有调节基因表达的作用的食物和饮料，其包括虾青素和/或其酯，并且可用于治疗，改善和/或预防由异常基因表达引起的症状，即过度表达或抑制的表达。

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