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1. 发明申请

WO2011106433A1 GANTRY IMAGE GUIDED RADIOTHERAPY SYSTEM AND RELATED TREATMENT DELIVERY METHODS 审中-公开
标题翻译： GANTRY图像指导放射治疗系统及相关治疗方法
公开(公告)号：WO2011106433A1
公开(公告)日：2011-09-01
申请号：PCT/US2011/025936
申请日：2011-02-23
申请人： ACCURAY INCORPORATED , MAURER, Calvin, R., Jr. , THOMSON, Euan, S.
发明人： MAURER, Calvin, R., Jr. , THOMSON, Euan, S.
IPC分类号： A61N5/10 , A61N5/00
CPC分类号： A61N5/1039 , A61B5/0035 , A61B5/0059 , A61B5/055 , A61B6/025 , A61B6/032 , A61B6/06 , A61B6/4014 , A61B6/4085 , A61B6/4435 , A61B6/4452 , A61B6/488 , A61N5/10 , A61N5/1037 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1067 , A61N5/1081 , A61N5/1082 , A61N2005/1061 , A61N2005/1062 , A61N2005/1092 , G01N2223/308
摘要： Systems, methods, and related computer program products for image- guided radiation treatment (IGRT) are described. Provided according to one preferred embodiment is an IGRT apparatus including a barrel-style rotatable gantry structure that provides high mechanical stability, versatility in radiation delivery, and versatility in target tracking. Methods for treatment radiation delivery using the IGRT apparatus include conical non-coplanar rotational arc therapy and cono-helical non-coplanar rotational arc therapy. A radiation treatment head (MV source) and a treatment guidance imaging system including a kV imaging source are mounted to and rotatable with a common barrel-style rotatable gantry structure, or alternatively the MV and kV sources are mounted to separate barrel-style rotatable gantry structures independently rotatable around a common axis of rotation. Methods for intra-fraction target tracking in a gantry-style IGRT system based on comparisons between a pre- acquired planning image and intrafraction x-ray tomosynthesis images and/or intrafraction cone beam CT (CBCT) images are also described.
摘要翻译：描述了用于图像引导辐射治疗（IGRT）的系统，方法和相关计算机程序产品。根据一个优选实施例提供了一种IGRT装置，其包括提供高机械稳定性，辐射传递多功能性和目标跟踪的多功能性的桶式可旋转机架结构。使用IGRT装置治疗放射线递送的方法包括锥形非共面旋转电弧治疗和螺旋非共面旋转电弧疗法。放射治疗头（MV源）和包括kV成像源的治疗引导成像系统安装到可旋转的机架式可旋转式结构上并可旋转，或者MV和kV源安装到独立的桶式可旋转机架可以围绕公共旋转轴线独立地旋转的结构。还描述了基于预获取的规划图像和影像内X射线断层合成图像和/或分数锥束CT（CBCT）图像之间的比较的龙门式IGRT系统中的部分内目标跟踪的方法。

2. 发明申请

WO2011156526A2 IMAGING METHODS AND TARGET TRACKING FOR IMAGE-GUIDED RADIATION TREATMENT 审中-公开
标题翻译：用于图像导向辐射治疗的成像方法和目标跟踪
公开(公告)号：WO2011156526A2
公开(公告)日：2011-12-15
申请号：PCT/US2011/039678
申请日：2011-06-08
申请人： ACCURAY, INC. , THOMSON, Euan, S. , MAURER, Calvin, R., Jr. , LEE, Mu, Young , KUDUVALLI, Gopinath , JORDAN, Petr , CHOPRA, Prashant
发明人： THOMSON, Euan, S. , MAURER, Calvin, R., Jr. , LEE, Mu, Young , KUDUVALLI, Gopinath , JORDAN, Petr , CHOPRA, Prashant
IPC分类号： G06T7/00 , A61N5/10
CPC分类号： A61N5/1067 , A61B6/025 , A61B6/032 , A61B6/4014 , A61B6/4071 , A61B6/4085 , A61B6/4458 , A61B6/482 , A61B6/488 , A61N5/1049 , A61N5/1083 , A61N2005/1061 , G06T7/0014 , G06T7/70 , G06T2200/04 , G06T2207/10112 , G06T2207/30004
摘要： Systems, methods, and related computer program products for medical imaging and image-guided radiation treatment (IGRT) are described. In one preferred embodiment, an IGRT system provides intrafraction target tracking based on a comparison of intrafraction x-ray tomosynthesis image data with initial x-ray tomosynthesis image data acquired with the patient in an initial treatment position, the initial x-ray tomosynthesis image data having an inherent registration with co-acquired image data from a setup imaging system integral with, or having known geometry relative to, the tomosynthesis imaging system. Repeated registration of intrafraction x-ray tomosynthesis image data with pre-acquired reference image data from a different frame of reference is not required during intrafraction radiation delivery. Selective integration therewith of x-ray source arrays, dual-energy imaging, stereoscopic imaging, static and dynamic source collimation, and/or inverse geometry tomosynthesis imaging are also described. Advantages include streamlined intrafraction computation, reduced patient x-ray dose, and/or reduced treatment delivery margins.
摘要翻译：描述了用于医学成像和图像引导辐射治疗（IGRT）的系统，方法和相关的计算机程序产品。在一个优选实施例中，IGRT系统基于将分数内x射线断层合成图像数据与在初始治疗位置中与患者获取的初始x射线断层合成图像数据的比较，初始x射线断层合成图像数据具有与来自与所述断层摄影成像系统成一体或具有已知几何形状的建立成像系统的共同获取的图像数据的固有配准。在分组内辐射传递期间，不需要从不同的参照系参考图像数据重新注册分组内x射线断层合成图像数据。还描述了与x射线源阵列，双能量成像，立体成像，静态和动态源准直以及/或反向几何断层合成成像的选择性整合。优点包括流线型内分泌计算，减少患者x射线剂量和/或减少治疗输送余量。

3. 发明公开

EP2539020A1 GANTRY IMAGE GUIDED RADIOTHERAPY SYSTEM AND RELATED TREATMENT DELIVERY METHODS 有权
标题翻译：图像引导放射治疗设备龙门吊
公开(公告)号：EP2539020A1
公开(公告)日：2013-01-02
申请号：EP11707282.7
申请日：2011-02-23
申请人： Accuray Incorporated
发明人： MAURER, Calvin, R., Jr. , THOMSON, Euan, S.
IPC分类号： A61N5/10 , A61N5/00
CPC分类号： A61N5/1039 , A61B5/0035 , A61B5/0059 , A61B5/055 , A61B6/025 , A61B6/032 , A61B6/06 , A61B6/4014 , A61B6/4085 , A61B6/4435 , A61B6/4452 , A61B6/488 , A61N5/10 , A61N5/1037 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1067 , A61N5/1081 , A61N5/1082 , A61N2005/1061 , A61N2005/1062 , A61N2005/1092 , G01N2223/308
摘要： Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. Provided according to one preferred embodiment is an IGRT apparatus including a barrel-style rotatable gantry structure that provides high mechanical stability, versatility in radiation delivery, and versatility in target tracking. Methods for treatment radiation delivery using the IGRT apparatus include conical non-coplanar rotational are therapy and cono-helical non-coplanar rotational are therapy. A radiation treatment head (MV source) and treatment guidance imaging system including a kV imaging source are mounted to and rotatable with a common barrel-style rotatable gantry structure, or alternatively the MV and kV sources are mounted to separate barrel-style rotatable gantry structures independently rotatable around a common axis of rotation. Methods for intra-fraction target tracking in a gantry-style IGRT system based on comparisons between a pre-acquired planning image and intrafraction x-ray tomosynthesis images and/or intrafraction cone beam CT (CBCT) images are also described.

4. 发明授权

EP2539020B1 GANTRY IMAGE GUIDED RADIOTHERAPY SYSTEM 有权
标题翻译： BILDGEFÜHRTESGANTRY-STRAHLENTHERAPIESYSTEM
公开(公告)号：EP2539020B1
公开(公告)日：2017-03-22
申请号：EP11707282.7
申请日：2011-02-23
申请人： Accuray Incorporated
发明人： MAURER, Calvin, R., Jr. , THOMSON, Euan, S.
IPC分类号： A61N5/10 , A61N5/00
CPC分类号： A61N5/1039 , A61B5/0035 , A61B5/0059 , A61B5/055 , A61B6/025 , A61B6/032 , A61B6/06 , A61B6/4014 , A61B6/4085 , A61B6/4435 , A61B6/4452 , A61B6/488 , A61N5/10 , A61N5/1037 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1067 , A61N5/1081 , A61N5/1082 , A61N2005/1061 , A61N2005/1062 , A61N2005/1092 , G01N2223/308
摘要： Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. Provided according to one preferred embodiment is an IGRT apparatus including a barrel-style rotatable gantry structure that provides high mechanical stability, versatility in radiation delivery, and versatility in target tracking. Methods for treatment radiation delivery using the IGRT apparatus include conical non-coplanar rotational are therapy and cono-helical non-coplanar rotational are therapy. A radiation treatment head (MV source) and treatment guidance imaging system including a kV imaging source are mounted to and rotatable with a common barrel-style rotatable gantry structure, or alternatively the MV and kV sources are mounted to separate barrel-style rotatable gantry structures independently rotatable around a common axis of rotation. Methods for intra-fraction target tracking in a gantry-style IGRT system based on comparisons between a pre-acquired planning image and intrafraction x-ray tomosynthesis images and/or intrafraction cone beam CT (CBCT) images are also described.
摘要翻译：描述了用于图像引导辐射治疗（IGRT）的系统，方法和相关计算机程序产品。根据一个优选实施例提供了一种IGRT装置，其包括提供高机械稳定性，辐射传递多功能性和目标跟踪的多功能性的桶形可旋转机架结构。使用IGRT装置的治疗放射线递送的方法包括锥形非共面旋转是治疗和螺旋非共面旋转治疗。包括一个kV成像源的辐射治疗头（MV源）和治疗引导成像系统安装在可旋转的机架式结构上并可旋转，或者，MV和kV源安装到独立的桶式可旋转机架结构可以围绕共同的旋转轴线独立地旋转。还描述了基于预采集的计划图像和影像内X射线断层合成图像和/或分数锥束CT（CBCT）图像之间的比较的龙门式IGRT系统中的部分内目标跟踪的方法。

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