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1. 发明申请

US20100330598A1 METHOD, SYSTEM, AND COMPUTER PROGRAM PRODUCT FOR PROVIDING BOTH AN ESTIMATED TRUE MEAN BLOOD GLUCOSE VALUE AND ESTIMATED GLYCATED HEMOGLOBIN (HbA1C) VALUE FROM STRUCTURED SPOT MEASUREMENTS OF BLOOD GLUCOSE 审中-公开
标题翻译：方法，系统和计算机程序产品，用于提供两个估计的平均血糖值和估计的糖化血红蛋白（HbA1C）价值从血液葡萄糖的结构化点测量
公开(公告)号：US20100330598A1
公开(公告)日：2010-12-30
申请号：US12492667
申请日：2009-06-26
申请人： Ajay Thukral , Stefan Weinert , Zhengzheng Pan
发明人： Ajay Thukral , Stefan Weinert , Zhengzheng Pan
IPC分类号： C12Q1/54 , G06F19/00
CPC分类号： A61B5/14532 , G06F19/3456
摘要： A method and system for providing both an estimated true mean blood glucose value and estimated glycated hemoglobin (HbA1C) value from spot blood glucose (bG) measurements are disclosed. The bG measurements and associated context of the bG measurement are collected at daily times specified by a structured sampling schema, and the collected bG measurements are weighted based on the associated context. The estimated true mean bG value and the estimate HbA1C value are then determined from the weighted measurements of the collected bG measurements. A computer program for implementing the method for providing both an estimated true mean blood glucose value and estimated glycated hemoglobin (HbA1C) value from spot blood glucose (bG) measurements is also disclosed.
摘要翻译：公开了一种从点血糖（bG）测量中提供估计的真实平均血糖值和估计的糖化血红蛋白（HbA1C）值的方法和系统。 bG测量和bG测量的相关上下文在由结构化采样模式指定的每日时间收集，并且收集的bG测量值基于相关联的上下文进行加权。然后从所收集的bG测量的加权测量中确定估计的真实平均值bG值和估计HbA1C值。还公开了一种用于实现从斑点血糖（bG）测量值提供估计的真实平均血糖值和估计的糖化血红蛋白（HbA1C）值的方法的计算机程序。

2. 发明申请

US20090326357A1 Method, system, and computer program product for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights 有权
标题翻译：方法，系统和计算机程序产品，用于计算具有时间权重的葡萄糖测量（或派生数量）的每日加权平均值
公开(公告)号：US20090326357A1
公开(公告)日：2009-12-31
申请号：US12215175
申请日：2008-06-25
申请人： Stefan Weinert , Ajay Thukral
发明人： Stefan Weinert , Ajay Thukral
IPC分类号： A61B5/00
CPC分类号： G06F19/3406 , A61B5/14532 , C12Q1/00 , G06F19/00 , G06F19/3456 , G16H40/63
摘要： A method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights are disclosed. The present invention computes an average daily glucose value using the time based weights based on only consecutive glucose measurements in the plurality of glucose measurements with acceptable time intervals that do not exceed a predefined maximum time interval. The invention further relates to a computer program for implementing the method for calculating daily weighted averages of spot monitoring glucose measurements (or derived quantities) with the time-based weights.
摘要翻译：公开了一种用于计算具有时间权重的葡萄糖测量（或派生数量）的每日加权平均值的方法和系统。本发明基于仅在不超过预定最大时间间隔的可接受的时间间隔的多个葡萄糖测量中仅连续的葡萄糖测量值，使用基于时间的权重来计算平均每日葡萄糖值。本发明还涉及一种计算机程序，用于实现用时间权重计算点监测葡萄糖测量（或派生量）的每日加权平均值的方法。

3. 发明申请

US20090006133A1 PATIENT INFORMATION INPUT INTERFACE FOR A THERAPY SYSTEM 审中-公开
标题翻译：患者信息输入界面治疗系统
公开(公告)号：US20090006133A1
公开(公告)日：2009-01-01
申请号：US12119207
申请日：2008-05-12
申请人： Stefan Weinert , Ajay Thukral
发明人： Stefan Weinert , Ajay Thukral
IPC分类号： G06Q50/00 , A61B5/145
CPC分类号： A61B5/4839 , A61B5/14503 , A61B5/14532 , G06Q50/24 , G16H15/00 , G16H50/50
摘要： A patient interface for a therapy system allows a patient to input information that characterizes at least one patient event or condition and from which therapy information can be determined. The patient interface may illustratively be formed by developing a patient model that is configured to simulate the patient's physiological response to the at least one patient event or condition, collecting patient-specific information over time that relates to actual occurrences of the at least one patient event or condition, and defining a graphical interface, based on the patient model and on the collected patient-specific information, that maps input from the patient of the information that characterizes the at least one patient event or condition to corresponding therapy information.
摘要翻译：用于治疗系统的患者界面允许患者输入表征至少一个患者事件或病症的信息，并且可以从哪个治疗信息确定。可以说明性地通过开发患者模型来形成患者界面，所述患者模型被配置为模拟患者对至少一个患者事件或病症的生理反应，收集与时间相关的患者特定信息，该信息与至少一个患者事件的实际发生相关或条件，并且基于患者模型和所收集的患者特定信息来定义图形界面，其将来自患者的来自表征所述至少一个患者事件或病症的信息的输入映射到相应的治疗信息。

4. 发明申请

US20070179434A1 System and method for determining drug administration information 有权
标题翻译：用于确定药物管理信息的系统和方法
公开(公告)号：US20070179434A1
公开(公告)日：2007-08-02
申请号：US11297733
申请日：2005-12-08
申请人： Stefan Weinert , Paul Galley , Ajay Thukral , Siva Chittajallu , Harvey Buck , Robin Wagner , Kym Marco , James Long , Stefan Bousamra
发明人： Stefan Weinert , Paul Galley , Ajay Thukral , Siva Chittajallu , Harvey Buck , Robin Wagner , Kym Marco , James Long , Stefan Bousamra
IPC分类号： A61M31/00 , A61B5/02
CPC分类号： G06F19/3456 , G06F9/451 , G06F19/00 , G16H40/63
摘要： A system for determining drug administration information may comprise an input device providing for user input of feed forward information having a first parameter component and a second parameter component, a data storage device and a processor. The data storage device may have stored therein a map correlating values of the first and second parameters to drug administration information. The processor may be responsive to user input of the feed forward information to determine corresponding drug administration information according to the map.
摘要翻译：用于确定药物管理信息的系统可以包括提供用户输入具有第一参数组件和第二参数组件的前馈信息的输入设备，数据存储设备和处理器。数据存储装置可以在其中存储将第一和第二参数的值与药物管理信息相关联的图。处理器可以响应于前馈信息的用户输入，以根据地图确定相应的药物管理信息。

5. 发明申请

US20120197536A1 METHOD, SYSTEM, AND COMPUTER PROGRAM PRODUCT FOR CALCULATING DAILY WEIGHTED AVERAGES OF GLUCOSE MEASUREMENTS (OR DERIVED QUANTITIES) WITH TIME-BASED WEIGHTS 有权
标题翻译：使用基于时间的权重计算葡萄糖测量（或衍生数量）的每日加权平均值的方法，系统和计算机程序产品
公开(公告)号：US20120197536A1
公开(公告)日：2012-08-02
申请号：US13439935
申请日：2012-04-05
申请人： Stefan Weinert , Ajay Thukral
发明人： Stefan Weinert , Ajay Thukral
IPC分类号： G06F19/00 , G01N33/66
CPC分类号： G06F19/3406 , A61B5/14532 , C12Q1/00 , G06F19/00 , G06F19/3456 , G16H40/63
摘要： A method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights are disclosed. The present invention computes an average daily glucose value using the time based weights based on only consecutive glucose measurements in the plurality of glucose measurements with acceptable time intervals that do not exceed a predefined maximum time interval. The invention further relates to a computer program for implementing the method for calculating daily weighted averages of spot monitoring glucose measurements (or derived quantities) with the time-based weights.
摘要翻译：公开了一种用于计算具有时间权重的葡萄糖测量（或派生数量）的每日加权平均值的方法和系统。本发明基于仅在不超过预定最大时间间隔的可接受的时间间隔的多个葡萄糖测量中仅连续的葡萄糖测量值，使用基于时间的权重来计算平均每日葡萄糖值。本发明还涉及一种计算机程序，用于实现用时间权重计算点监测葡萄糖测量（或派生量）的每日加权平均值的方法。

6. 发明授权

US08175812B2 Method, system, and computer program product for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights 有权
标题翻译：方法，系统和计算机程序产品，用于计算具有时间权重的葡萄糖测量（或派生数量）的每日加权平均值
公开(公告)号：US08175812B2
公开(公告)日：2012-05-08
申请号：US12215175
申请日：2008-06-25
申请人： Stefan Weinert , Ajay Thukral
发明人： Stefan Weinert , Ajay Thukral
IPC分类号： G01N33/48
CPC分类号： G06F19/3406 , A61B5/14532 , C12Q1/00 , G06F19/00 , G06F19/3456 , G16H40/63
摘要： A method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights are disclosed. The present invention computes an average daily glucose value using the time based weights based on only consecutive glucose measurements in the plurality of glucose measurements with acceptable time intervals that do not exceed a predefined maximum time interval. The invention further relates to a computer program for implementing the method for calculating daily weighted averages of spot monitoring glucose measurements (or derived quantities) with the time-based weights.
摘要翻译：公开了一种用于计算具有时间权重的葡萄糖测量（或派生数量）的每日加权平均值的方法和系统。本发明基于仅在不超过预定最大时间间隔的可接受的时间间隔的多个葡萄糖测量中仅连续的葡萄糖测量值，使用基于时间的权重来计算平均每日葡萄糖值。本发明还涉及一种计算机程序，用于实现用时间权重计算点监测葡萄糖测量（或派生量）的每日加权平均值的方法。

7. 发明申请

US20090006061A1 SYSTEM FOR DEVELOPING PATIENT SPECIFIC THERAPIES BASED ON DYNAMIC MODELING OF PATIENT PHYSIOLOGY AND METHOD THEREOF 有权
标题翻译：基于患者生理学动态建模的患者特异性治疗系统及其方法
公开(公告)号：US20090006061A1
公开(公告)日：2009-01-01
申请号：US12119143
申请日：2008-05-12
申请人： Ajay Thukral , Paul Galley , Siva Chittajallu , Stefan Weinert
发明人： Ajay Thukral , Paul Galley , Siva Chittajallu , Stefan Weinert
IPC分类号： G06G7/48
CPC分类号： G06F19/3437 , A61M5/1723 , A61M2005/14296 , G06F19/00 , G06F19/325 , G06F19/3456 , G06F19/3468 , G06F19/3475 , G06F19/3481 , G06F19/36 , G16H10/20 , G16H50/20 , G16H50/50
摘要： A system for developing patient-specific therapies based on dynamic modeling of patient-specific physiology and method thereof are disclosed. The system includes software modules configured to provide access via a computer to one or more data collection protocols defining at least a type of patient-specific data to be collected and a manner in which the patient-specific data is to be collected, and to information from which one or more patient-specific models, configured to simulate one or more aspects of the patient's physiology, is developed. Another software module of the system is configured to provide access via the computer to one or more software tools that apply patient-specific data, collected according to the one or more data collection protocols, to the one or more patient specific models to determine therefrom one or more patient-specific therapies.
摘要翻译：公开了一种基于患者特异性生理学的动态建模及其方法开发患者特异性疗法的系统。该系统包括软件模块，被配置为经由计算机向一个或多个数据收集协议提供访问，所述数据收集协议至少定义了要收集的患者特定数据类型，以及要收集患者特定数据的方式以及信息开发了用于模拟患者生理学的一个或多个方面的一个或多个患者特异性模型。该系统的另一个软件模块被配置为经由计算机向一个或多个软件工具提供访问，该软件工具将根据一个或多个数据收集协议收集的患者特定数据应用于一个或多个患者特定模型，从而确定一个或更多的患者特异性疗法。

8. 发明申请

US20060276771A1 System and method providing for user intervention in a diabetes control arrangement 审中-公开
标题翻译：提供糖尿病控制安排中的用户干预的系统和方法
公开(公告)号：US20060276771A1
公开(公告)日：2006-12-07
申请号：US11145910
申请日：2005-06-06
申请人： Paul Galley , Ajay Thukral , Siva Chittajallu , Robin Wagner , Stefan Weinert , Steven Bousamra
发明人： Paul Galley , Ajay Thukral , Siva Chittajallu , Robin Wagner , Stefan Weinert , Steven Bousamra
IPC分类号： A61M31/00
CPC分类号： A61M5/172 , A61M5/1723 , A61M2005/14208 , A61M2005/14296 , A61M2205/3569 , A61M2230/201 , G06F19/3468 , G16H50/50
摘要： A system providing for user intervention in a medical control arrangement may comprise a first user intervention mechanism responsive to user selection thereof to produce a first user intervention signal, a second user intervention mechanism responsive to user selection thereof to produce a second user intervention signal, and a processor executing a drug delivery algorithm forming part of the medical control arrangement. The processor may be responsive to the first user intervention signal to include an intervention therapy value in the execution of the drug delivery algorithm, and responsive to the second user intervention signal to exclude the intervention therapy value from the execution of the drug delivery algorithm. The medical control arrangement may be a diabetes control arrangement, the drug delivery algorithm may be an insulin delivery algorithm, and the intervention therapy value may be, for example, an intervention insulin quantity or an intervention carbohydrate quantity.
摘要翻译：提供用户干预医疗控制装置的系统可以包括响应于用户选择其以产生第一用户干预信号的第一用户干预机制，响应于用户选择以产生第二用户干预信号的第二用户干预机制，以及执行形成医疗控制装置的一部分的药物递送算法的处理器。所述处理器可以响应于所述第一用户干预信号，以在所述药物递送算法的执行中包括干预治疗值，并且响应于所述第二用户干预信号排除所述介入治疗值与所述药物递送算法的执行。医疗控制装置可以是糖尿病控制装置，药物递送算法可以是胰岛素递送算法，并且干预治疗值可以是例如干预胰岛素量或干预碳水化合物量。

9. 发明授权

US06544212B2 Diabetes management system 有权
标题翻译：糖尿病管理系统
公开(公告)号：US06544212B2
公开(公告)日：2003-04-08
申请号：US09918623
申请日：2001-07-31
申请人： Paul J. Galley , Ajay Thukral , Siva K. Chittajallu , Stefan Weinert
发明人： Paul J. Galley , Ajay Thukral , Siva K. Chittajallu , Stefan Weinert
IPC分类号： A61M100
CPC分类号： A61B5/14532 , A61B5/7275 , G06F19/00 , G06F19/3456
摘要： A system is provided that enables glycemic control for a subject. The system includes an insulin delivery unit, a glucose sensor, and a control unit. The control unit includes a processor unit that receives glucose value readings from the glucose sensor, executes an algorithm that predicts a glucose value at a predetermined time in the future, compares that predicted glucose value to a pre-determined glucose value range, and determines a corrective amount of insulin to be administered when the predictive glucose value lies outside of the predetermined glucose value range. The control unit also includes a communication unit that transmits the corrective amount to the delivery unit.
摘要翻译：提供了能够使受试者进行血糖控制的系统。该系统包括胰岛素输送单元，葡萄糖传感器和控制单元。控制单元包括处理器单元，其从葡萄糖传感器接收葡萄糖值读数，执行在将来的预定时间预测葡萄糖值的算法，将该预测葡萄糖值与预定葡萄糖值范围进行比较，并确定当预测葡萄糖值处于预定葡萄糖值范围之外时要施用的胰岛素的校正量。控制单元还包括将校正量发送到传送单元的通信单元。

10. 发明授权

US09092553B2 Method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time based-weights 有权
标题翻译：用时间基准权重计算葡萄糖测量（或派生数量）的每日加权平均值的方法和系统
公开(公告)号：US09092553B2
公开(公告)日：2015-07-28
申请号：US13439935
申请日：2012-04-05
申请人： Stefan Weinert , Ajay Thukral
发明人： Stefan Weinert , Ajay Thukral
IPC分类号： C12Q1/00 , G06F19/00 , A61B5/145
CPC分类号： G06F19/3406 , A61B5/14532 , C12Q1/00 , G06F19/00 , G06F19/3456 , G16H40/63
摘要： A method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights are disclosed. The present invention computes an average daily glucose value using the time based weights based on only consecutive glucose measurements in the plurality of glucose measurements with acceptable time intervals that do not exceed a predefined maximum time interval. The invention further relates to a computer program for implementing the method for calculating daily weighted averages of spot monitoring glucose measurements (or derived quantities) with the time-based weights.
摘要翻译：公开了一种用于计算具有时间权重的葡萄糖测量（或派生数量）的每日加权平均值的方法和系统。本发明基于仅在不超过预定最大时间间隔的可接受的时间间隔的多个葡萄糖测量中仅连续的葡萄糖测量值，使用基于时间的权重来计算平均每日葡萄糖值。本发明还涉及一种计算机程序，用于实现用时间权重计算点监测葡萄糖测量（或派生量）的每日加权平均值的方法。

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