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1. 发明申请

WO2016126622A1 NICKEL HYDROXIDE POSITIVE ELECTRODE FOR ALKALINE RECHARGEABLE BATTERY 审中-公开
标题翻译：用于碱性可充电电池的镍氢氧化物电极
公开(公告)号：WO2016126622A1
公开(公告)日：2016-08-11
申请号：PCT/US2016/016041
申请日：2016-02-02
申请人： BASF CORPORATION , YOUNG, Kwo , WANG, Lixin , MAYS, William , REICHMAN, Benjamin
发明人： YOUNG, Kwo , WANG, Lixin , MAYS, William , REICHMAN, Benjamin , CHAO-IAN, Hu , WONG, Diana , NEI, Jean
IPC分类号： H01M4/52 , H01M4/62 , H01M10/30
CPC分类号： H01M4/52 , H01M4/32 , H01M4/62 , H01M10/345 , H01M2004/021
摘要： A nickel hydroxide cathode active material for use in an alkaline rechargeable electrochemical cell, which active material is capable of transferring >1.67 electrons per Ni atom. A nickel hydroxide cathode active material for use in an alkaline rechargeable electrochemical cell, where the specific capacity of the material is ≥330mAh/g. A nickel hydroxide cathode active material for use in an alkaline rechargeable electrochemical cell, where Ni reaches an oxidation state of less than +2 during charge/discharge cycling of an alkaline rechargeable cell.
摘要翻译：一种用于碱性可再充电电化学电池的氢氧化镍阴极活性材料，该活性材料能够每个Ni原子传递> 1.67个电子。用于碱性可再充电电化学电池的氢氧化镍阴极活性材料，其中材料的比容量≥330mAh/ g。一种用于碱性可再充电电池的氢氧化镍阴极活性材料，其中Ni在碱性可再充电电池的充电/放电循环期间达到小于+2的氧化态。

2. 发明申请

WO2010029350A1 TREATMENT OF FIBROTIC EYE DISORDERS 审中-公开
标题翻译：纤维性眼病的治疗
公开(公告)号：WO2010029350A1
公开(公告)日：2010-03-18
申请号：PCT/GB2009/051146
申请日：2009-09-09
申请人： UNIVERSITY OF EAST ANGLIA , WORMSTONE, Ian Michael , DAWES, Lucy , ELDRED, Julie Ann , WANG, Lixin
发明人： WORMSTONE, Ian Michael , DAWES, Lucy , ELDRED, Julie Ann , WANG, Lixin
IPC分类号： A61K31/00 , A61K31/18 , A61K31/44 , A61K31/47 , A61K31/495 , A61P27/02 , A61P27/12
CPC分类号： A61K31/00 , A61K31/18 , A61K31/44 , A61K31/47 , A61K31/495
摘要： Inhibitors of myosin activity are used to treat or prevent a fibrotic disorder of the eye, for example posterior capsule opacification (PCO).
摘要翻译：肌球蛋白活性抑制剂用于治疗或预防眼睛的纤维化疾病，例如后囊膜混浊（PCO）。

3. 发明申请

WO2007030588A1 USE OF REPLICATORS TO PREVENT GENE SILENCING 审中-公开
标题翻译：使用替代者预防基因沉默
公开(公告)号：WO2007030588A1
公开(公告)日：2007-03-15
申请号：PCT/US2006/034812
申请日：2006-09-07
申请人： THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAM SERVICES , ALADJEM, Mirit, I. , TSENG, Cindy , FU, Haiqing , WANG, Lixin
发明人： ALADJEM, Mirit, I. , TSENG, Cindy , FU, Haiqing , WANG, Lixin
IPC分类号： C12N15/79
CPC分类号： C12N15/79
摘要： Regulatory elements, specifically replicators and transgene constructs containing replicator nucleic acid sequences, are disclosed herein. Methods of using replicators and transgene constructs including replicators to inhibit, delay, or prevent gene silencing are also disclosed herein.
摘要翻译：本文公开了包含复制子核酸序列的调节元件，特别是复制子和转基因构建体。本文还公开了使用包括复制子在内的复制子和转基因构建体抑制，延迟或预防基因沉默的方法。

4. 发明申请

WO2011146863A1 SURGICAL COMPOSITIONS CONTAINING SIGMA-RECEPTOR AGONISTS 审中-公开
标题翻译：含有SIGMA-受体激动剂的外用组合物
公开(公告)号：WO2011146863A1
公开(公告)日：2011-11-24
申请号：PCT/US2011/037384
申请日：2011-05-20
申请人： ALCON RESEARCH, LTD. , WANG, Lixin , ONG, Marcia, Danielle , TSAI, Chi-Chun , HARTZER, Michael
发明人： WANG, Lixin , ONG, Marcia, Danielle , TSAI, Chi-Chun , HARTZER, Michael
IPC分类号： A61K31/485 , A61K45/06 , A61P27/02 , A61P27/04
CPC分类号： A61K31/137 , A61K9/0048 , A61K9/08 , A61K31/15 , A61K31/341 , A61K31/439 , A61K31/485 , A61K31/495 , A61K31/726 , A61K45/06 , A61K47/26 , A61K2300/00
摘要： One aspect of the present invention relates to aqueous surgical compositions comprising a sigma-1 receptor agonist. Another aspect of the present invention relates to methods of irrigating ocular tissues during an ophthalmic surgical procedure such as cataract surgery. Such methods comprise bathing the ocular tissues with a composition comprising a sigma-1 receptor agonist.
摘要翻译：本发明的一个方面涉及包含σ-1受体激动剂的含水手术组合物。本发明的另一方面涉及在诸如白内障手术的眼科手术过程中冲洗眼组织的方法。这种方法包括用包含σ-1受体激动剂的组合物洗澡眼组织。

5. 发明申请

WO2011104568A1 TREATMENT OF OXIDATIVE STRESS DISORDERS 审中-公开
标题翻译：治疗氧化应激障碍
公开(公告)号：WO2011104568A1
公开(公告)日：2011-09-01
申请号：PCT/GB2011/050386
申请日：2011-02-25
申请人： UNIVERSITY OF EAST ANGLIA , WANG, Lixin , WORMSTONE, Ian Michael
发明人： WANG, Lixin , WORMSTONE, Ian Michael
IPC分类号： A61K31/00 , A61K31/485 , A61P27/02
CPC分类号： A61K31/00 , A61K31/485
摘要： The use, in the treatment or prevention of ocular lens degeneration, corneal degeneration, skin degeneration or any ROS-induced degeneration of other tissues or organs characterised by the ER stress response, or in the preparation of a medicament for such degeneration treatment or prevention, of an active therapeutic agent comprising one or more sigma 1 receptor agonist.
摘要翻译：用于治疗或预防眼部变性，角膜变性，皮肤变性或其它组织或器官的任何ROS诱导的变性，其特征在于ER应激反应，或用于制备用于这种变性治疗或预防的药物，包含一种或多种σ1受体激动剂的活性治疗剂。

6. 发明申请

WO2007149938A2 METHODS FOR PROMOTING HAIR GROWTH 审中-公开
标题翻译：促进头发生长的方法
公开(公告)号：WO2007149938A2
公开(公告)日：2007-12-27
申请号：PCT/US2007/071695
申请日：2007-06-20
申请人： THE SALK INSTITUTE BIOLOGICAL STUDIES , THE REGENTS OF UNIVERSITY OF CALIFORNIA , MILLION, Mulugeta , WANG, Lixin , TACHE, Yvette , RIVIER, Jean
发明人： MILLION, Mulugeta , WANG, Lixin , TACHE, Yvette , RIVIER, Jean
IPC分类号： A61K38/17
CPC分类号： A61K38/17
摘要： This disclosure reveals that cyclic corticotrophin releasing factor (CRF) antagonist peptides (such as astressin B, its functional fragments, and their derivatives) induce hair growth and prevent hair loss in vivo. This important discovery enables, for instance, methods of promoting hair growth, and methods of treating hair loss (such as the hair loss that occurs normally in some individuals or that is the result of a health disorder or therapeutic treatment). Exemplary cyclic CRF antagonist peptides useful in the disclosed methods are provided throughout the disclosure.
摘要翻译：本公开揭示了循环促肾上腺皮质激素释放因子（CRF）拮抗剂肽（例如阿斯匹林B，其功能片段及其衍生物）诱导毛发生长并预防体内脱发。这个重要的发现使得例如促进毛发生长的方法和治疗脱发的方法（例如在一些个体中正常发生的那些脱发，或者是健康障碍或治疗性治疗的结果）。在本公开内容中提供了可用于所公开方法的示例性环状CRF拮抗剂肽。

7. 发明申请

WO2017119979A1 NICKEL HYDROXIDE COMPOSITE MATERIAL FOR ALKALINE RECHARGEABLE BATTERY 审中-公开
标题翻译：用于碱性可充电电池的氢氧化镍复合材料
公开(公告)号：WO2017119979A1
公开(公告)日：2017-07-13
申请号：PCT/US2016/065155
申请日：2016-12-06
申请人： BASF CORPORATION
发明人： YOUNG, Kwo , MAYS, William, C. , WANG, Lixin
IPC分类号： H01M4/36 , H01M4/525 , H01M4/02
CPC分类号： H01M4/32 , C01G53/006 , C01P2002/85 , C01P2004/03 , C01P2004/04 , C01P2004/32 , C01P2004/61 , C01P2006/11 , C01P2006/12 , C01P2006/14 , H01M4/28 , H01M4/362 , H01M4/52 , H01M4/626 , H01M2004/021
摘要： Provided are uniquely structured electrochemically active particles characterized by a first electrochemically active material and a second electrochemically active material disposed about the first material whereby at least the second material includes a modifier present as a continuous transition concentration gradient from the first material into the second material whereby the concentration is lower in the first material than the second material. Also provided are processes of producing the particle and electrochemical cells incorporating the particles as a positive electrode material in a cathode.
摘要翻译：提供了独特结构的电化学活性颗粒，其特征在于第一电化学活性材料和围绕第一材料设置的第二电化学活性材料，由此至少第二材料包括作为连续过渡浓度梯度存在的改性剂，第一材料进入第二材料中，由此第一材料中的浓度低于第二材料。还提供了生产颗粒和电化学电池的方法，所述颗粒和电化学电池包含颗粒作为正极材料在阴极中。

8. 发明申请

WO2016077303A1 ELECTROLYTES AND METAL HYDRIDE BATTERIES 审中-公开
标题翻译：电解液和金属氢化物电池
公开(公告)号：WO2016077303A1
公开(公告)日：2016-05-19
申请号：PCT/US2015/059883
申请日：2015-11-10
申请人： BASF CORPORATION
发明人： YOUNG, Kwo , NEI, Jean , WONG, Diana , LI, Wentao , WANG, Lixin
IPC分类号： H01M10/34 , H01M10/26 , H01M4/38
CPC分类号： H01M10/345 , H01M4/383 , H01M10/26 , H01M2300/0014 , H01M2300/0017
摘要： A metal hydride battery comprising an electrolyte composition comprising an ionic compound selected from the group consisting of protic acids, protic ammonium compounds, protic oxonium compounds, aprotic ammonium compounds, aprotic oxonium compounds, aprotic phosphonium compounds and alkali or alkali earth metal salts; or comprising an ionic compound selected from the group consisting of alkali or alkali earth metal hydroxides and alkali or alkali earth metal alkoxides and an organic solvent; or comprising an alkali metal hydroxide, water and one or more further components selected from the group consisting of organic solvents, further ionic compounds and additives; or comprising an ionic compound selected from the group consisting of carboxylate compounds and carboxylic acids. Ionic compounds include ionic liquids and salts. Metal hydride batteries comprising certain electrolyte compositions have a nominal open-circuit voltage of from about 1.5 V to about 5.0 V.
摘要翻译：一种金属氢化物电池，其包含电解质组合物，所述电解质组合物包含选自质子酸，质子铵化合物，质子氧化合物，非质子性铵化合物，非质子性氧化合物，非质子鏻化合物和碱金属或碱土金属盐的离子化合物; 或包含选自碱金属或碱土金属氢氧化物和碱金属或碱土金属醇盐和有机溶剂的离子化合物; 或包含碱金属氢氧化物，水和一种或多种选自有机溶剂，其它离子化合物和添加剂的其它组分; 或包含选自羧酸酯化合物和羧酸的离子化合物。离子化合物包括离子液体和盐。包含某些电解质组合物的金属氢化物电池具有约1.5V至约5.0V的标称开路电压。

9. 发明公开

EP3400625A1 NICKEL HYDROXIDE COMPOSITE MATERIAL FOR ALKALINE RECHARGEABLE BATTERY 审中-公开
公开(公告)号：EP3400625A1
公开(公告)日：2018-11-14
申请号：EP16884155.9
申请日：2016-12-06
申请人： BASF Corporation
发明人： YOUNG, Kwo , MAYS, William, C. , WANG, Lixin
IPC分类号： H01M4/36 , H01M4/525 , H01M4/02
CPC分类号： H01M4/32 , C01G53/006 , C01P2002/85 , C01P2004/03 , C01P2004/04 , C01P2004/32 , C01P2004/61 , C01P2006/11 , C01P2006/12 , C01P2006/14 , H01M4/28 , H01M4/362 , H01M4/52 , H01M4/626 , H01M2004/021
摘要： Provided are uniquely structured electrochemically active particles characterized by a first electrochemically active material and a second electrochemically active material disposed about the first material whereby at least the second material includes a modifier present as a continuous transition concentration gradient from the first material into the second material whereby the concentration is lower in the first material than the second material. Also provided are processes of producing the particle and electrochemical cells incorporating the particles as a positive electrode material in a cathode.

10. 发明公开

EP3218955A1 ELECTROLYTES AND METAL HYDRIDE BATTERIES 审中-公开
标题翻译：电解质和金属氢化物电池
公开(公告)号：EP3218955A1
公开(公告)日：2017-09-20
申请号：EP15859568.6
申请日：2015-11-10
申请人： BASF Corporation
发明人： YOUNG, Kwo , NEI, Jean , WONG, Diana , LI, Wentao , WANG, Lixin
IPC分类号： H01M10/34 , H01M10/26 , H01M4/38
CPC分类号： H01M10/345 , H01M4/383 , H01M10/26 , H01M2300/0014 , H01M2300/0017
摘要： A metal hydride battery comprising an electrolyte composition comprising an ionic compound selected from the group consisting of protic acids, protic ammonium compounds, protic oxonium compounds, aprotic ammonium compounds, aprotic oxonium compounds, aprotic phosphonium compounds and alkali or alkali earth metal salts; or comprising an ionic compound selected from the group consisting of alkali or alkali earth metal hydroxides and alkali or alkali earth metal alkoxides and an organic solvent; or comprising an alkali metal hydroxide, water and one or more further components selected from the group consisting of organic solvents, further ionic compounds and additives; or comprising an ionic compound selected from the group consisting of carboxylate compounds and carboxylic acids. Ionic compounds include ionic liquids and salts. Metal hydride batteries comprising certain electrolyte compositions have a nominal open-circuit voltage of from about 1.5 V to about 5.0 V.
摘要翻译：一种包含电解质组合物的金属氢化物电池，所述电解质组合物包含选自质子酸，质子铵化合物，质子氧鎓化合物，非质子铵化合物，非质子性氧鎓化合物，非质子鏻化合物和碱金属或碱土金属盐的离子化合物; 或包含选自碱金属或碱土金属氢氧化物和碱金属或碱土金属醇盐和有机溶剂的离子化合物; 或包含碱金属氢氧化物，水和一种或多种选自有机溶剂，其他离子化合物和添加剂的其他组分的组分; 或者包含选自羧酸酯化合物和羧酸的离子化合物。离子化合物包括离子液体和盐。包含某些电解质组合物的金属氢化物电池具有约1.5V至约5.0V的标称开路电压。

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