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    • 4. 发明申请
    • Polymer Compositions for Dual or Multi Staged Curing
    • 双组分或多分段固化的聚合物组合物
    • US20070225387A1
    • 2007-09-27
    • US10591606
    • 2005-03-03
    • Roshan MayadunnePathiraja GunatillakeRaju Adhkari
    • Roshan MayadunnePathiraja GunatillakeRaju Adhkari
    • C08G18/10C09D167/07C09D175/16C09J167/07C09J175/16
    • C08G18/10C08G18/3206C08G18/4277C08G18/428C08G18/4854C08G18/7664C08G18/771C08G18/775C08G18/8025C08G18/8116C08G18/42
    • The present invention provides a polymer composition for use at least in surface coating applications and in fabrication of rigid foams with load bearing capacity comprising a base molecule, a linker molecule and at least one initiator compound, said base molecule having at least two differing functionalities, and said linker molecule having a functionality reactive with at least one functionality of said base molecule, the first of said at least two functionalities of said base molecule enabling a first curing stage of said polymer composition by reaction with said linker molecule, and the second and any further functionality of said base molecule enabling second and further curing stages of said polymer composition, said first, second and any further curing stages being capable of activation simultaneously or independently of each other as required. A further provides uses of the polymer compositions of the invention in surface coating and adhesives applications and in the preparation of rigid foams with load bearing capacity.
    • 本发明提供一种聚合物组合物,其用于至少在表面涂覆应用中并用于制造具有承载能力的刚性泡沫体,其具有包含基础分子,连接分子和至少一种引发剂化合物,所述碱基分子具有至少两个不同的官能团, 并且所述连接分子具有与所述碱基分子的至少一个官能度反应的官能度,所述碱基分子的所述至少两个官能团中的第一个能够通过与所述连接分子的反应来实现所述聚合物组合物的第一固化阶段, 所述基础分子的任何另外的功能使得所述聚合物组合物的第二和进一步固化阶段,所述第一,第二和任何其它固化阶段能够根据需要同时或彼此独立地活化。 本发明的聚合物组合物进一步提供了表面涂层和粘合剂应用以及制备具有承载能力的刚性泡沫的用途。
    • 5. 发明申请
    • Biocompatible polymer compositions for dual or multi staged curing
    • 用于双阶段或多阶段固化的生物相容性聚合物组合物
    • US20050197422A1
    • 2005-09-08
    • US11070217
    • 2005-03-03
    • Roshan MayadunneRaju AdhikariPathiraja Gunatillake
    • Roshan MayadunneRaju AdhikariPathiraja Gunatillake
    • A61K6/00A61K6/087A61L24/04A61L27/18A61L31/06C08G18/10C09J167/07C09J175/16
    • C08G18/10C08G18/3206C08G18/4277C08G18/428C08G18/4854C08G18/7671C08G18/771C08G18/8116C08L75/16C08L101/16
    • The present invention provides a biocompatible polymer composition for use in biomedical applications comprising a base molecule, a linker molecule and at least one initiator compound, said base molecule having at least two differing functionalities, and said linker molecule having a functionality reactive with at least one functionality of said base molecule, the first of said at least two functionalities of said base molecule enabling a first curing stage of said polymer composition by reaction with said linker molecule, and the second and any further functionality of said base molecule enabling second and further curing stages of said polymer composition, said first, second and any further curing stages being capable of activation simultaneously or independently of each other as required. The invention further provides uses of the polymer compositions of the invention in biomedical applications such as tissue engineering, dry delivery, as a bioadhesive in wound healing, as bone substitutes or scaffolds, as cements in dental and periodontal applications and as anti-adhesives or protective barriers.
    • 本发明提供了用于生物医学应用的生物相容性聚合物组合物,其包含基础分子,连接分子和至少一种引发剂化合物,所述碱基分子具有至少两个不同的官能团,并且所述连接分子具有与至少一个 所述碱基分子的功能性,所述碱基分子的所述至少两个官能团中的第一个能够通过与所述连接分子的反应来实现所述聚合物组合物的第一固化阶段,并且所述碱基分子的第二和任何其它官能团能够进行第二次和进一步固化 所述聚合物组合物的阶段,所述第一,第二和任何其它固化阶段能够根据需要同时或彼此独立地活化。 本发明进一步提供本发明的聚合物组合物在生物医学应用中的用途,例如组织工程,干燥递送,作为伤口愈合中的生物粘合剂,作为骨替代物或支架,用作牙科和牙周应用中的水泥,以及作为抗粘合剂或保护性 障碍