专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2004108140A1 COMPOSITION FOR INHIBITING DIFFERENTIATION OR GROWTH OF FAT CELLS 审中-公开
标题翻译：抑制脂肪细胞分化或生长的组合物
公开(公告)号：WO2004108140A1
公开(公告)日：2004-12-16
申请号：PCT/KR2004/001314
申请日：2004-06-02
申请人： DOOSAN CORPORATION , HWANG, You-A , CHOI, Wangkeun , KIM, Jinwook , PARK, Changseo , NAM, Sang June , CHUNG, So Young
发明人： HWANG, You-A , CHOI, Wangkeun , KIM, Jinwook , PARK, Changseo , NAM, Sang June , CHUNG, So Young
IPC分类号： A61K31/685
CPC分类号： A61K31/685
摘要： The present invention relates to a composition for inhibiting differentiation or growth of fat cells including sebocytes, which contains phosphatidylcholine (PC) and/or hydrogenated phosphatidylcholine (HPC) as an active ingredient. The composition is effective in treatment or prevention of fat cell-related diseases, particularly obesity or acne through inhibiting of differentiation or growth of fat cells such as sebocytes. Further, the composition can be used in combination with other compositions or other active ingredients in treatment or prevention of many fat cell-related diseases.
摘要翻译：本发明涉及抑制包含磷脂酰胆碱（PC）和/或氢化磷脂酰胆碱（HPC）作为活性成分的脂质细胞分化或生长的组合物。该组合物通过抑制脂肪细胞如脂蛋白的分化或生长，有效地治疗或预防脂肪细胞相关疾病，特别是肥胖或痤疮。此外，组合物可以与其它组合物或其它活性成分组合使用，以治疗或预防许多脂肪细胞相关疾病。

2. 发明申请

WO2005030161A1 COMPOSITION FOR PROTECTING SKIN 审中-公开
标题翻译：保护皮肤的组合物
公开(公告)号：WO2005030161A1
公开(公告)日：2005-04-07
申请号：PCT/KR2004/002517
申请日：2004-10-01
申请人： DOOSAN CORPORATION , PARK, Changseo , KIM, Sunki , KIM, Jinwook , KANG, HyeongJoon , HAN, Bokyung , LEE, Younggon , CHUNG, Soyoung , CHOI, Wangkeun , NAM, Sang June
发明人： PARK, Changseo , KIM, Sunki , KIM, Jinwook , KANG, HyeongJoon , HAN, Bokyung , LEE, Younggon , CHUNG, Soyoung , CHOI, Wangkeun , NAM, Sang June
IPC分类号： A61K7/48
CPC分类号： A61K8/04 , A61K8/68 , A61K2800/413 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/08 , B82Y5/00
摘要： Disclosed are a composition for protecting skin and uses thereof. The composition comprises sphingomyelin as an active ingredient and protects the skin by inhibiting skin aging, treating a skin wound and improving a skin barrier.
摘要翻译：公开了一种用于保护皮肤及其用途的组合物。组合物包含鞘磷脂作为活性成分，通过抑制皮肤老化，治疗皮肤伤口和改善皮肤屏障来保护皮肤。

3. 发明申请

WO2005118521A1 MONOMETHYLPHYTOSPHINGOSINE AND THE COMPOSITION FOR ANTI-CANCER CONTAINING THE SAME 审中-公开
标题翻译：单甲基磷灰石和含有其的抗癌组合物
公开(公告)号：WO2005118521A1
公开(公告)日：2005-12-15
申请号：PCT/KR2005/001436
申请日：2005-05-17
申请人： DOOSAN CORPORATION , LIM, Dae-Seog , KIM, Jinwook , PARK, Sungjin , HWANG, You-A , PARK, Changseo , LEE, Ho-Jae
发明人： LIM, Dae-Seog , KIM, Jinwook , PARK, Sungjin , HWANG, You-A , PARK, Changseo , LEE, Ho-Jae
IPC分类号： C07C215/10
CPC分类号： C07C215/10
摘要： Disclosed are a monomethylphytosphingosine (MMPS) or a pharmaceutically acceptable salt thereof and a composition containing the same. The compound can highly inhibit an activity of sphingosine kinase and thus interrupt many mechanisms caused by the sphingosine kinase. In particular, the invention prevents ceramide and sphingosine from being phosphorylated due to sphingosine kinase to maintain concentrations of ceramide and sphingosine to be high, thereby inducing apoptosis of a cancer cell and thus treating or preventing a cancer or a cancer-related disease. In addition, since the invention inhibits a cell proliferation-promoting activity of sphingosine kinase and thus can treat or prevent a hyper-proliferative disease such as cancer or psoriasis.
摘要翻译：公开了单甲基鞘氨醇（MMPS）或其药学上可接受的盐和含有它们的组合物。该化合物可以高度抑制鞘氨醇激酶的活性，从而中断由鞘氨醇激酶引起的许多机制。特别地，本发明防止神经酰胺和鞘氨醇由于鞘氨醇激酶而被磷酸化，以保持神经酰胺和鞘氨醇的浓度高，从而诱导癌细胞凋亡，从而治疗或预防癌症或癌症相关疾病。此外，由于本发明抑制鞘氨醇激酶的细胞增殖促进活性，因此可以治疗或预防高增殖性疾病如癌症或牛皮癣。

4. 发明申请

WO2006080589A1 SPHINGOLIPID-PEG DERIVATIVES AND COMPOSITION FOR SKIN EXTERNAL USE CONTAINING THE DERIVATIVES 审中-公开
标题翻译： SPHINGOLIPID-PEG衍生物及含有衍生物的外用皮肤组合物
公开(公告)号：WO2006080589A1
公开(公告)日：2006-08-03
申请号：PCT/KR2004/003382
申请日：2004-12-21
申请人： DOOSAN CORPORATION , PARK, Sungjin , HWANG, You-A , KIM, Jinwook , PARK, Changseo
发明人： PARK, Sungjin , HWANG, You-A , KIM, Jinwook , PARK, Changseo
IPC分类号： C07C233/20
CPC分类号： C08G65/333 , A61K8/68 , A61K8/86 , A61K47/60 , A61K2800/57 , A61Q19/02
摘要： Disclosed are sphingolipid-PEG derivatives, which comprise sphingolipid selected from the group consisting of N-acetylphytosphigosine, N-acetylsphiganine and N-acetylsphingadiene and polyethylene glycol, and compositions for skin external use containing the derivatives. The sphingolipid-PEG derivatives and the compositions exhibit an improved skin whitening effect. Further, the derivatives and compositions show an improved solubility of sphingolipid and a decreased toxicity and, accordingly, can be used broadly.
摘要翻译：公开了鞘脂-PEG衍生物，其包含选自N-乙酰头孢菌素，N-乙酰激素和N-乙酰鞘氨二烯和聚乙二醇的鞘脂，以及含有衍生物的外用皮肤组合物。鞘脂-PEG衍生物和组合物表现出改善的皮肤美白效果。此外，衍生物和组合物显示出鞘脂的溶解度提高和毒性降低，因此可广泛使用。

5. 发明申请

WO2005118522A1 MONOMETHYLPHYTOSPHINGOSINE- POLYETHYLENEGLY COL AND THE COMPOSITION FOR ANTI-CANCER CONTAINING THE SAME 审中-公开
标题翻译：单甲基磷杂环磷酰胺 - 聚乙烯醚和含有其的抗癌组合物
公开(公告)号：WO2005118522A1
公开(公告)日：2005-12-15
申请号：PCT/KR2005/001438
申请日：2005-05-17
申请人： DOOSAN CORPORATION , LIM, Dae-Seog , KIM, Jinwook , PARK, Sungjin , HWANG, You-A , PARK, Changseo , LEE, Ho-Jae
发明人： LIM, Dae-Seog , KIM, Jinwook , PARK, Sungjin , HWANG, You-A , PARK, Changseo , LEE, Ho-Jae
IPC分类号： C07C215/10
CPC分类号： C07C219/06
摘要： Disclosed are a monomethylphytosphingosine-polyethyleneglycol (MMPS-PEG) derivative formed by combining monomethylphytosphingosine (MMPS), which is a derivative of sphingolipid, with polyethyleneglycol (PEG) or a pharmaceutically acceptable salt thereof and a composition containing the same. The compound inhibits a growth of tumor xenografted to the mammal, thereby treating or preventing a cancer or a cancer-related disease. In addition, it is possible to inhibit an activity of promoting a cell proliferation, thereby treating or preventing a hyper-proliferative disease such as a cancer and psoriasis. Further, a solubility of the monomethylphytosphingosine is improved and a toxicity thereof influencing on the human body is reduced, thereby remarkably expanding the application ranges thereof.
摘要翻译：公开了通过将作为鞘脂的衍生物的单甲基鞘氨醇（MMPS）与聚乙二醇（PEG）或其药学上可接受的盐和含有它们的组合物组合而形成的单甲基鞘氨醇 - 聚乙二醇（MMPS-PEG）衍生物。该化合物抑制异种移植到哺乳动物的肿瘤的生长，从而治疗或预防癌症或癌症相关疾病。此外，可以抑制促进细胞增殖的活性，从而治疗或预防高增殖性疾病如癌症和牛皮癣。此外，改善了单甲基鞘氨醇的溶解性，降低了对人体的毒性，从而显着扩大了其应用范围。

6. 发明申请

WO2005063688A1 SPHINGOLIPID-RUCINOL DERIVATIVES AND COMPOSITION FOR SKIN EXTERNAL USE CONTAINING THE DERIVATIVES 审中-公开
标题翻译：皮质激素 - 赖氨酸衍生物及含有衍生物的外用皮肤组合物
公开(公告)号：WO2005063688A1
公开(公告)日：2005-07-14
申请号：PCT/KR2004/003446
申请日：2004-12-24
申请人： DOOSAN CORPORATION , PARK, Sungjin , HWANG, You-A , KIM, Jinwook , PARK, Changseo
发明人： PARK, Sungjin , HWANG, You-A , KIM, Jinwook , PARK, Changseo
IPC分类号： C07C233/20
CPC分类号： C07C235/80 , A61K8/68 , A61Q19/02
摘要： Disclosed are sphingolipid-rucinol derivatives, which comprise sphingolipid selected from the group consisting of N-acetylphytosphigosine, N-acetylsphiganine and N-acetylsphingadiene, and rucinol, and compositions for skin external use containing the derivatives. The sphingolipid-rucinol derivatives and the compositions exhibit an improved skin whitening effect. Further, the derivatives and compositions show an improved solubility of sphingolipid and a decreased toxicity and, accordingly, have broad applications.
摘要翻译：公开了含有选自N-乙酰头孢菌素，N-乙酰激素和N-乙酰鞘氨二烯的神经鞘脂，以及赖in诺和含有该衍生物的外用皮肤组合物的鞘脂 - 莽草酸衍生物。鞘脂 - 岩藻糖醇衍生物和组合物表现出改善的皮肤美白效果。此外，衍生物和组合物显示出鞘脂的溶解度提高和毒性降低，因此具有广泛的应用。

7. 发明申请

WO2006004359A1 SPHINGOLIPID DERIVATIVES AND THE COMPOSITION FOR ANTI-CANCER CONTAINING THE SAME 审中-公开
标题翻译：皮质激素衍生物及其含有抗癌剂的组合物
公开(公告)号：WO2006004359A1
公开(公告)日：2006-01-12
申请号：PCT/KR2005/002102
申请日：2005-07-01
申请人： DOOSAN CORPORATION , IMAGENE CO., LTD. , KIM, Jinwook , PARK, Sungjin , LEE, Ho-Jae , PARK, Changseo , KIM, Yong-woo , LEE, Won-koo , HA, Hyun-joon
发明人： KIM, Jinwook , PARK, Sungjin , LEE, Ho-Jae , PARK, Changseo , KIM, Yong-woo , LEE, Won-koo , HA, Hyun-joon
IPC分类号： C07C233/18
CPC分类号： C07C233/18 , C07C215/28
摘要： Disclosed are a novel sphingolipid derivative having a sphingosine kinase suppressing activity and a composition containing the same. When the newly synthesized sphingolipid derivative of the invention is used, it is possible to maintain concentrations of ceramide and sphingosine to be high by preventing ceramide and sphingosine from being phosphorylated due to sphingosine kinase since an activity of sphingosine kinase is suppressed. In addition, since the apoptosis is induced in a cancer cell by ceramide and sphingosine, it is possible to treat or prevent a cancer or disease related to the cancer. Further, it is possible to treat or prevent a hyper- proliferative disease such as cancer or proliferation-promoting activity of sphingosine kinase. Accordingly, the composition containing the same can be used as a composition for suppressing sphingosine kinase and a composition for treating or preventing a cancer or hyper-proliferative disease.
摘要翻译：公开了具有鞘氨醇激酶抑制活性的新型鞘脂衍生物和含有鞘氨醇激酶抑制活性的组合物。当使用本发明的新合成的鞘脂衍生物时，由于鞘氨醇激酶的活性被抑制，因此通过防止神经酰胺和鞘氨醇由于鞘氨醇激酶而被磷酸化，可以使神经酰胺和鞘氨醇的浓度保持高。此外，由于通过神经酰胺和鞘氨醇在癌细胞中诱导凋亡，因此可以治疗或预防与癌症相关的癌症或疾病。此外，可以治疗或预防高增殖性疾病如癌症或鞘氨醇激酶的增殖促进活性。因此，含有该组合物的组合物可以用作抑制鞘氨醇激酶的组合物和用于治疗或预防癌症或高增殖性疾病的组合物。

8. 发明申请

WO2019066111A1 FLOW CONTROL VALVE AND HYDRAULIC MACHINE INCLUDING THE SAME 审中-公开
公开(公告)号：WO2019066111A1
公开(公告)日：2019-04-04
申请号：PCT/KR2017/011033
申请日：2017-09-29
申请人： VOLVO CONSTRUCTION EQUIPMENT AB , KIM, Jinwook
发明人： KIM, Jinwook
IPC分类号： F15B13/04 , F16K11/07
摘要： A flow control valve is disclosed. A valve body has an inner circumferential surface defining a longitudinal bore to which at least a portion of first and second fluid passages is connected. A spool is slidably inserted into the bore to allow a flow of fluid from the first to second fluid passage. A valve regulates a flow rate of fluid flowing through the first fluid passage. A first seat surface is defined between an area in which the first fluid passage is connected to the bore and an area in which the second fluid passage is connected to the bore. When the flow of fluid from the first to second fluid passage is initiated, an area of a gap between the first seat surface and the spool on a plane taken in a transverse direction is 5%~50%, preferably 10%~20% of an area of an opening defined by the first seat surface.

9. 发明申请

WO2012161407A1 METHOD OF MOTION TRACKING 审中-公开
标题翻译：运动跟踪方法
公开(公告)号：WO2012161407A1
公开(公告)日：2012-11-29
申请号：PCT/KR2012/001119
申请日：2012-02-15
申请人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , KIM, Jinwook , JUNG, Yujin , KANG, Donghoon
发明人： KIM, Jinwook , JUNG, Yujin , KANG, Donghoon
IPC分类号： A61B5/103 , A61B5/11
CPC分类号： G01B5/004 , A61B5/1114 , A61B5/6822 , A61B5/6823 , A61B5/6824 , A61B5/6825 , A61B5/6828 , A61B5/6829 , A61B5/6831 , A61B2503/10 , A61B2505/09 , G06F3/011
摘要： A motion of a model including a joint, at least one body part that rotates with respect to the joint, and a plurality of inertial sensors attached to each body part and measuring a rotational motion of the body part is tracked by obtaining a rotational matrix of a sensor coordinate system fixed to each of the inertial sensors with respect to an inertial coordinate system fixed to ground, by using a signal measured by the inertial sensor attached to each body part; obtaining a rotational matrix of the sensor coordinate systems with respect to a body part coordinate system fixed to each body part, by using an obtained rotational matrix value of the sensor coordinate system; obtaining a rotational matrix of each body part coordinate system with respect to the inertial coordinate system, by using a calculated rotational matrix of the sensor coordinate systems; and calculating a joint variable with respect to each body part, by using a calculated rotational matrix of the body part coordinate system.
摘要翻译：包括关节的模型的运动，相对于关节旋转的至少一个身体部分以及附接到每个身体部分并测量身体部位的旋转运动的多个惯性传感器被跟踪，通过获得通过使用由附接到每个身体部分的惯性传感器测量的信号，相对于固定在地面上的惯性坐标系固定到每个惯性传感器的传感器坐标系; 通过使用获得的传感器坐标系的旋转矩阵值，获得相对于固定到每个身体部位的身体部位坐标系的传感器坐标系的旋转矩阵; 通过使用计算出的传感器坐标系的旋转矩阵获得每个身体部位坐标系相对于惯性坐标系的旋转矩阵; 以及通过使用身体部位坐标系的计算旋转矩阵来计算关于每个身体部位的关节变量。

10. 发明申请

WO2010044509A1 MOTION TRACKING METHOD USING SCANNING DEVICE 审中-公开
标题翻译：使用扫描设备的运动跟踪方法
公开(公告)号：WO2010044509A1
公开(公告)日：2010-04-22
申请号：PCT/KR2008/006881
申请日：2008-11-21
申请人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , KIM, Jinwook , HONG, Seungpyo , KO, Heedong
发明人： KIM, Jinwook , HONG, Seungpyo , KO, Heedong
IPC分类号： H04N1/04 , H04N5/00
CPC分类号： G01S17/66
摘要： The motion tracking method disclosed herein suggests a method for precisely tracking the motion of a scanning device by correcting the surrounding information distortedly recognized due to the time differences between pieces of information regarding the surroundings of the device over one scanning cycle. The method, as a motion tracking method of a scanning device collecting the surrounding information corresponding to a plurality of the points of the surroundings, includes collecting the surrounding information, obtaining the displacement data of the scanning device using the surrounding information, updating the velocity of the scanning device using the displacement data of the scanning device, correcting the surrounding information using the updated velocity of the scanning device, and determining location and position information of the scanning device using the corrected surrounding information. According to the method herein, the motion of the scanning device may be more precisely tracked because the surrounding information is corrected based on the velocity of the scanning device.
摘要翻译：本文公开的运动跟踪方法提出了一种通过校正由于在一个扫描周期上与设备的周围环境相关的信息之间的时间差异而失真识别的周围信息来精确跟踪扫描设备的运动的方法。作为收集与周围的多个点对应的周围信息的扫描装置的运动跟踪方法，包括收集周围信息，使用周围信息获取扫描装置的位移数据，更新速度所述扫描装置使用所述扫描装置的位移数据，使用所述扫描装置的更新速度来校正所述周围信息，以及使用所述校正的周围信息来确定所述扫描装置的位置和位置信息。根据本文的方法，可以更精确地跟踪扫描装置的运动，因为基于扫描装置的速度来校正周围的信息。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式