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    • 1. 发明公开
    • A METHOD AND SYSTEM FOR PRION INACTIVATION
    • 一种用于突变灭活的方法和系统
    • KR20070098752A
    • 2007-10-05
    • KR20070032423
    • 2007-04-02
    • ETHICON INC
    • ROBERTS CHARLES GFAVERO MARTIN
    • A61L2/14A61L2/00A61L2/02A61L2/07
    • A61L2/208A61L2/14A61L2202/122
    • A method and a system for prion inactivation are provided to prevent prion disease like CJD or CJDv in a host by inactivating the prion with several methods including a method of decomposing one or more chemical coupling of the prion. A method for prion inactivation includes the steps of: putting an article having a large amount of prion on the surface thereof into a sterilizing chamber(12); reducing the pressure inside the sterilizing chamber to be less than the steam pressure of a hydrogen peroxide; putting a solution containing a hydrogen peroxide into the sterilizing chamber, and making the article come into contact with the vapor of the hydrogen peroxide; and inactivating the prion inside the chamber through the contact between the prion and the vapor of the hydrogen peroxide.
    • 提供了用于朊病毒失活的方法和系统,以通过用几种方法灭活朊病毒来防止宿主中的CJD或CJDv等朊病毒病,包括分解朊病毒的一种或多种化学偶联的方法。 朊病毒灭活的方法包括以下步骤:将具有大量朊病毒的物品放置在灭菌室(12)的表面上。 将灭菌室内的压力降低至小于过氧化氢的蒸汽压力; 将含有过氧化氢的溶液放入灭菌室,使制品与过氧化氢的蒸气接触; 并通过朊病毒与过氧化氢的蒸气之间的接触来灭活室内的朊病毒。