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1. 发明专利

JP2008189573A Sleep inducer and stress insomnia ameliorating agent 有权
标题翻译：睡眠诱导器和应激性胰岛素调节剂
公开(公告)号：JP2008189573A
公开(公告)日：2008-08-21
申请号：JP2007024306
申请日：2007-02-02
申请人： Fancl Corp , Kyushu Univ , 国立大学法人九州大学 , 株式会社ファンケル
发明人： KAN TSUTOMU , HAYAMIZU KOSUKE , FURUSE MITSUHIRO , YAMANE HARUKA
IPC分类号： A61K38/00 , A23L1/305 , A61P25/20
摘要： PROBLEM TO BE SOLVED: To provide a sleep inducer and a stress insomnia ameliorating agent. SOLUTION: The sleep inducer comprises a dipeptide in which the constituent amino acid is selected from glutamic acid, cysteine and glycine. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供睡眠诱导剂和压力失眠改善剂。解决方案：睡眠诱导剂包含其中构成氨基酸选自谷氨酸，半胱氨酸和甘氨酸的二肽。版权所有（C）2008，JPO＆INPIT

2. 发明专利

JP2008056628A Sleep inducer and stress insomnia ameliorating agent 审中-公开
标题翻译：睡眠诱导器和应激性胰岛素调节剂
公开(公告)号：JP2008056628A
公开(公告)日：2008-03-13
申请号：JP2006237603
申请日：2006-09-01
申请人： Fancl Corp , Kyushu Univ , 国立大学法人九州大学 , 株式会社ファンケル
发明人： KAN TSUTOMU , HAYAMIZU KOSUKE , TOMI HIROTAKA , FURUSE MITSUHIRO , YAMANE HARUKA
IPC分类号： A61K38/00 , A23K1/16 , A23L1/305 , A61P25/20
摘要： PROBLEM TO BE SOLVED: To provide a sleep inducer and a stress insomnia ameliorating agent. SOLUTION: The sleep inducer comprises glutathione. The stress insomnia ameliorating agent comprises the glutathione. Furthermore, in the sleep inducer or stress insomnia ameliorating agent, the glutathione is produced by any method of a protein hydrolysis method, a chemical synthesis method, an enzyme method, a fermentation method or extraction or purification from a natural raw material. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供睡眠诱导剂和压力失眠改善剂。解决方案：睡眠诱导剂包括谷胱甘肽。压力失眠改善剂包括谷胱甘肽。此外，在睡眠诱导剂或压力失眠改善剂中，谷胱甘肽通过蛋白质水解法，化学合成法，酶法，发酵法或天然原料的提取或纯化的任何方法制备。版权所有（C）2008，JPO＆INPIT

3. 发明专利

JP2010184901A APOPTOSIS INHIBITOR CONTAINING ESSENCE OF CISTANCHE DESERTICOLA Y. C. Ma, DNA DAMAGE INHIBITOR AND ACTIVE OXYGEN (ROS) INHIBITOR 有权
标题翻译：抗坏血酸抑制剂含有西妥昔单抗的药物Y.C.Ma，DNA损伤抑制剂和活性氧（ROS）抑制剂
公开(公告)号：JP2010184901A
公开(公告)日：2010-08-26
申请号：JP2009030761
申请日：2009-02-13
申请人： Fancl Corp , Peking Univ , 北京大学Peking University , 株式会社ファンケル
发明人： KAN TSUTOMU , TU PENGFEI , MA ZHIZHONG
IPC分类号： A61K36/18 , A61P39/06 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To develop an agent for suppressing apoptosis or inhibiting DNA damage. SOLUTION: The agent for suppressing apoptosis contains essence of Cistanche deserticola Y. C. Ma. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：开发抑制细胞凋亡或抑制DNA损伤的药剂。解决方案：抑制细胞凋亡的药物含有肉istan蓉的精华。版权所有（C）2010，JPO＆INPIT

4. 发明专利

JP2005087110A Mumefural-containing fruit extract and method for producing the same 有权
标题翻译：含有水果的果汁提取物及其生产方法
公开(公告)号：JP2005087110A
公开(公告)日：2005-04-07
申请号：JP2003325666
申请日：2003-09-18
申请人： Fancl Corp , 株式会社ファンケル
发明人： KAN TSUTOMU
IPC分类号： A23L1/212 , A23L1/30
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a mumefural-containing fruit extract and to provide the mumefural-containing fruit extract. SOLUTION: The method for producing the mumefural-containing fruit extract is carried out as follows. A fruit juice obtained from a fruit [except an Ume (a Japanese plum)] is use as a raw material and two stages of a concentration step and a heating step are included. In the concentration step, the moisture content of the fruit extract raw material is reduced to ≤50 mass%. In the heating step, the moisture content is then maintained. The mumefural-containing fruit extract is provided. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：待解决的问题：提供一种制备含有水乳液的果实提取物的方法，并提供含有水乳液的果实提取物。解决方案：含有水乳液的果实提取物的制造方法如下进行。从果实获得的果汁（除了Ume（日本李子）]用作原料，并且包括两个阶段的浓缩步骤和加热步骤。在浓缩步骤中，水果提取物原料的水分含量降低至≤50质量％。在加热步骤中，保持水分含量。提供含有水乳液的果实提取物。版权所有（C）2005，JPO＆NCIPI

5. 发明专利

JP2008105977A Anti-anxiety agent 审中-公开
标题翻译：抗静电剂
公开(公告)号：JP2008105977A
公开(公告)日：2008-05-08
申请号：JP2006288926
申请日：2006-10-24
申请人： Fancl Corp , Kyushu Univ , 国立大学法人九州大学 , 株式会社ファンケル
发明人： KAN TSUTOMU , HAYAMIZU KOSUKE , FURUSE MITSUHIRO
IPC分类号： A61K31/198 , A23K1/16 , A23L1/305 , A61P25/22
摘要： PROBLEM TO BE SOLVED: To provide a pharmaceutical, food, food for specific health, nutritive functional food or health food, each having such anti-anxiety function as not to develop serious side effects including drug dependence, excitement and confusion attributable to its mass and continuous uptake, or light side effects including drowsiness, dizziness, weakness, constipation, anorexia and hepatic dysfunction attributable to its uptake in small amounts and for a short period, inherent in conventional anti-anxiety agents. SOLUTION: An anti-anxiety agent is provided, containing alanine. The alanine is produced by either one of the following methods: protein hydrolysis, chemical synthesis, enzymic method, fermentation, and extraction and purification from natural raw material(s). COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：为特定健康，营养功能性食品或保健食品提供制药，食品，食品，每种具有抗焦虑功能，不会产生严重的副作用，包括药物依赖性，兴奋性和混淆性，可归因于其质量和持续摄取，或轻微的副作用，包括由常规抗焦虑剂固有的少量摄入和短时间引起的嗜睡，头晕，虚弱，便秘，厌食和肝功能障碍。解决方案：提供含有丙氨酸的抗焦虑剂。丙氨酸通过以下任一方法产生：蛋白质水解，化学合成，酶法，发酵，以及天然原料的提取和纯化。版权所有（C）2008，JPO＆INPIT

6. 发明专利

JP2005112731A Hepatic function ameliorating agent 有权
标题翻译：自动功能调理剂
公开(公告)号：JP2005112731A
公开(公告)日：2005-04-28
申请号：JP2003345154
申请日：2003-10-03
申请人： Fancl Corp , 株式会社ファンケル
发明人： KAN TSUTOMU , TSUJI TOMOKO , YAMAGUCHI KOJI , YAZAWA KAZUYOSHI , KOBAYASHI NOE
IPC分类号： A23L1/30 , A61K31/661 , A61P1/16
摘要： PROBLEM TO BE SOLVED: To provide a medicine and a functional food effective for prophylaxis, amelioration and treatment of various kinds of hepatic dysfunctions such as viral hepatitis, alcoholic hepatopathy or drug hepatopathy. SOLUTION: A hepatic function ameliorating agent comprises phosphatidylserine as an active ingredient. In the hepatic function ameliorating agent, the phosphatidylserine is produced from lecithin using a base exchange reaction with an enzyme. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供对预防，改善和治疗各种肝功能异常如病毒性肝炎，酒精性肝病或药物性肝病有效的药物和功能性食品。解决方案：肝功能改善剂包括磷脂酰丝氨酸作为活性成分。在肝功能改善剂中，使用与酶的碱交换反应由卵磷脂产生磷脂酰丝氨酸。版权所有（C）2005，JPO＆NCIPI

7. 发明专利

JP2004081014A Ume extract with high mumefural content and method for producing the same 有权
公开(公告)号：JP2004081014A
公开(公告)日：2004-03-18
申请号：JP2002242631
申请日：2002-08-22
申请人： Fancl Corp , 株式会社ファンケル
发明人： KAN TSUTOMU
IPC分类号： A23L1/212 , A23L1/30
摘要： PROBLEM TO BE SOLVED: To attain a high mumefural content in a fruit extract and to provide a method for simply and stably producing the same and to obtain a composition having a high-quality flavor. SOLUTION: The fruit extract composition with the high mumefural content has≥0.5 mass% mumefural content in the fruit extract and ≥10 mass% fruit extract content in the whole composition. The method for simply and stably producing the same is provided and a method for producing the fruit extract composition having the high mumefural content and the high-quality flavor is to produce the Ume (Japanese prune) extract with the high mumefural content. The production process comprises two steps of a concentrating step and a heating step. In the concentrating step, water content is reduced and the mumefural is then produced while maintaining the water content in the heating step. The water content in the extract to be processed is ≤40 mass% and pressurization is carried out in the heating step. Furthermore, saccharides or citric acid are added before the finish into the extract in the heating step. COPYRIGHT: (C)2004,JPO

8. 发明专利

JP2006321732A REMOVAL OF ABNORMAL PROTEIN, AND COMPOSITION FOR SUPPRESSING INCREASE OF 8-HYDROXY-2'-DEOXYGUANOSINE 审中-公开
公开(公告)号：JP2006321732A
公开(公告)日：2006-11-30
申请号：JP2005144853
申请日：2005-05-18
申请人： FANCL CORP
发明人： KIN TATSUYA , KAN TSUTOMU , MIHARA KAZUNOBU
IPC分类号： A61K31/381 , A23L1/30 , A61P3/10 , A61P9/10 , A61P13/12 , A61P17/16 , A61P21/02 , A61P25/16 , A61P25/28 , A61P27/12 , A61P43/00 , C07D339/04
摘要： PROBLEM TO BE SOLVED: To provide a composition for removing abnormal proteins comprising a highly effective abnormal protein-removing component, and to provide an anti-ageing composition contributing to prevention and treatments of diseases caused by abnormal proteolysis using the abnormal protein-removing component. SOLUTION: The composition comprises α-lipoic acid as the abnormal protein-removing component. Health foods and beauty foods comprising the same are also provided. The composition for suppressing the increase of 8-hydroxy-2'-deoxyguanosine comprises α-lipoic acid. COPYRIGHT: (C)2007,JPO&INPIT

9. 发明专利

JP2006104103A Oral composition comprising difructose anhydride 有权
标题翻译：口服组合物包含不溶形式的非氢化物
公开(公告)号：JP2006104103A
公开(公告)日：2006-04-20
申请号：JP2004291541
申请日：2004-10-04
申请人： Fancl Corp , 株式会社ファンケル
发明人： TAMURA AKIKO , KAN TSUTOMU , SHIGEMATSU NORIHIRO
IPC分类号： A61K31/7012 , A23K1/16 , A23K1/18 , A23L1/30 , A61P3/12 , C07H3/04
CPC分类号： A23K50/40 , A23K20/105 , A23K20/163 , A23L33/10 , A23V2002/00 , A61K31/7016 , A23V2250/606 , A23V2250/506 , A23V2250/5118
摘要： PROBLEM TO BE SOLVED: To obtain a new composition and a prophylactic ameliorating agent, and to provide a food and drink and a pet feed, ameliorating adverse effects of excessive ingestion of common salt which is one cause of onset and aggravation of diseases belonging to life style related diseases and complications thereof, and to improve the freedom of a meal of a person carrying injury in the kidney by promoting the excretion of sodium and/or potassium. SOLUTION: The subject oral composition for promoting the excretion of the sodium and/or potassium comprises a DFA (difructose anhydride) as an active ingredient for promoting the excretion of the sodium and/or potassium. COPYRIGHT: (C)2006,JPO&NCIPI

10. 发明专利

JP2005247841A Anti-anxiety agent 有权
标题翻译：抗静电剂
公开(公告)号：JP2005247841A
公开(公告)日：2005-09-15
申请号：JP2005029114
申请日：2005-02-04
申请人： Fancl Corp , 株式会社ファンケル
发明人： HAYAMIZU KOSUKE , KAN TSUTOMU , TSUJI TOMOKO , FURUSE MITSUHIRO
IPC分类号： A23L1/305 , A61K31/198 , A61K31/661 , A61P25/22
摘要： PROBLEM TO BE SOLVED: To provide a safe anti-anxiety agent without causing adverse effects. SOLUTION: The anti-anxiety agent is characterized as comprising one or two or more kinds selected from a compound having a serine unit, cysteine, phosphatidic acid and glycine. COPYRIGHT: (C)2005,JPO&NCIPI

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