专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2009011858A1 ABSORBABLE TISSUE DRESSING ASSEMBLIES, SYSTEMS, AND METHODS FORMED FROM A HYDROPHILIC CHITOSAN SPONGE STRUCTURE AND INCLUDING A FLEXIBLE ABSORBABLE BACKING LAYER OF POLY-4-HYDROXY BUTYRATE 审中-公开
标题翻译：可吸收的组织装配组件，系统和方法由聚合的壳聚糖海绵结构形成，并包括聚-4-羟基丁酸酯的柔性可吸收的背层
公开(公告)号：WO2009011858A1
公开(公告)日：2009-01-22
申请号：PCT/US2008/008665
申请日：2008-07-16
申请人： HEMCON MEDICAL TECHNOLOGIES, INC. , MCCARTHY, Simon , MCGRATH, Barbara , WINATA, Ervelyn
发明人： MCCARTHY, Simon , MCGRATH, Barbara , WINATA, Ervelyn
IPC分类号： A61F13/00
CPC分类号： A61F13/00995 , A61F13/00063 , A61F2013/00157 , A61F2013/00472 , A61F2013/00519 , A61F2013/00931 , A61L15/28 , A61L15/425 , A61L15/64 , C08L5/08
摘要： Absorbable tissue dressing assemblies are formed from hydrophilic polymer sponge structures, such as chitosan.
摘要翻译：可吸收组织敷料组件由亲水聚合物海绵结构如壳聚糖形成。

2. 发明申请

WO2009011856A1 ABSORBABLE TISSUE DRESSING ASSEMBLIES, SYSTEMS, AND METHODS FORMED FROM HYDROPHILIC POLYMER SPONGE STRUCTURES SUCH AS CHISTOSAN 审中-公开
标题翻译：可吸收的组织，系统和方法由氢化聚合物海绵结构如CHISTOSAN
公开(公告)号：WO2009011856A1
公开(公告)日：2009-01-22
申请号：PCT/US2008/008660
申请日：2008-07-16
申请人： HEMCON MEDICAL TECHNOLOGIES, INC. , MCCARTHY, Simon , MCGRATH, Barbara , WINATA, Ervelyn
发明人： MCCARTHY, Simon , MCGRATH, Barbara , WINATA, Ervelyn
IPC分类号： A61F13/00
CPC分类号： A61F13/00995 , A61F13/00063 , A61F2013/00157 , A61F2013/00472 , A61F2013/00519 , A61F2013/00931 , A61L15/28 , A61L15/425 , A61L15/64 , C08L5/08
摘要： Absorbable tissue dressing assemblies are formed from hydrophilic polymer sponge structures, such as chitosan.
摘要翻译：可吸收组织敷料组件由亲水聚合物海绵结构如壳聚糖形成。

3. 发明申请

WO2015120085A1 CHITOSAN MATERIALS FROM CARBONIC ACID SOLUTION 审中-公开
标题翻译：来自碳酸溶液的CHITOSAN材料
公开(公告)号：WO2015120085A1
公开(公告)日：2015-08-13
申请号：PCT/US2015/014507
申请日：2015-02-04
申请人： HEMCON MEDICAL TECHNOLOGIES, INC.
发明人： MCCARTHY, Simon , MCGRATH, Barbara , KUHN, Sam , KIMBALL, Jess , STOLTEN, Michael , BENNETT, Amanda
IPC分类号： A61K31/722
CPC分类号： A61K31/722 , A61K9/1652 , A61K9/1694 , A61K9/19 , A61K9/70 , A61K47/12
摘要： The present invention comprises chitosan materials and methods of using carbonic acid for aqueous solubilization of neutralized or pre-treated chitosan gels and provides, among other things, substantially acid salt free composition native final forms without requiring subsequent acid salt elution. The invention includes chitosan-based solid and semi-solid material forms, optionally reinforced with chitosan fibers, such as powders, fibers, films, matrices, sponges, implants, scaffolds, fillers, and hydrogels. Native final forms are produced from chitosan powder solubilized in an aqueous acidic solution, processed to form a high pH hydrated chitosan gel precipitate material that is then neutralized by water washing and re-solubilized substantially to chitosan solution using carbonic acid. Chitosan materials can be mixed in solution with one or more of other hydrophilic polymers to create compositional heterogeneity and pharmaceutical agents to achieve controlled release of the agent(s) from the final forms at the site of application.
摘要翻译：本发明包括壳聚糖材料和使用碳酸进行中和或预处理的壳聚糖凝胶的水溶性增溶的方法，并且除其他外，还提供基本上无酸盐的组合物天然最终形式，而不需要随后的酸盐洗脱。本发明包括任选用壳聚糖纤维如粉末，纤维，薄膜，基质，海绵，植入物，支架，填料和水凝胶增强的基于壳聚糖的固体和半固体材料形式。天然最终形式由溶解在酸性水溶液中的壳聚糖粉末制备，加工形成高pH水合壳聚糖凝胶沉淀物质，然后通过水洗中和，并使用碳酸基本上再溶解于壳聚糖溶液。壳聚糖材料可以与一种或多种其它亲水性聚合物在溶液中混合以产生组成异质性和药剂，以在施用部位从最终形式控制释放试剂。

4. 发明申请

WO2014152796A2 BIOCOMPATIBLE AND BIOABSORBABLE DERIVATIZED CHITOSAN COMPOSITIONS 审中-公开
标题翻译：生物成分和生物可溶性衍生化的CHITOSAN组合物
公开(公告)号：WO2014152796A2
公开(公告)日：2014-09-25
申请号：PCT/US2014/027766
申请日：2014-03-14
申请人： HEMCON MEDICAL TECHNOLOGIES, INC.
发明人： MCGRATH, Barbara , MCCARTHY, Simon , KUHN, Sam , WOLD, Alysha , STOLTEN, Michael , BENNETT, Amanada
IPC分类号： A61L27/20 , C08B37/08 , A61K47/36 , G01N33/68
CPC分类号： A61L27/58 , A61K9/0024 , A61K47/36 , A61K49/0008 , A61L27/20 , A61L27/26 , A61L2400/04 , C08B37/003 , C08L5/08 , C08L89/06 , C08L2201/06 , G01N33/5014 , G01N33/6869 , G01N2333/545 , G01N2400/28
摘要： The invention relates to biocompatible, bioabsorbable derivatized non-crosslinked chitosan compositions optionally crosslinked to gelatin/collagen by 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride (EDC) for biomedical use and methods of making and testing such compositions, including a modified acute systemic toxicity test. The compositions comprise derivatized chitosan reacetylated to a degree of N-deacetylation (DDA) of between about 15% and 40%. The compositions are typically bioabsorbed in about 90 days or less and can be made to bioabsorb at differing rates of speed. The compositions are initially soluble in aqueous solution below pH 6.5. The compositions have an acid content that can be adjusted between about 0% (w/w) and about 8% (w/w) to customize the composition for uses that require and/or tolerate differing levels of cytotoxicity, adhesion, composition cohesion, and cell infiltration into the composition.
摘要翻译：本发明涉及用于生物医学使用的1-乙基-3- [3-二甲基氨基丙基]碳二亚胺盐酸盐（EDC），任选地交联至明胶/胶原的生物相容性，生物可吸收的衍生的非交联壳聚糖组合物，以及制备和测试这些组合物的方法，包括改良型急性全身毒性试验。组合物包含重新乙酰化至约15％至40％的N-脱乙酰度（DDA）的衍生的壳聚糖。组合物通常在约90天或更短时间内生物吸收，并且可以以不同的速度制成生物吸收。组合物最初可溶于低于pH6.5的水溶液中。组合物的酸含量可以在约0％（w / w）至约8％（w / w）之间调节，以定制需要和/或耐受不同水平的细胞毒性，粘附性，组成内聚力，和细胞浸润到组合物中。

5. 发明公开

EP2173293A1 ABSORBABLE TISSUE DRESSING ASSEMBLIES, SYSTEMS, AND METHODS FORMED FROM HYDROPHILIC POLYMER SPONGE STRUCTURES SUCH AS CHISTOSAN 审中-公开
标题翻译：可吸收纺织协会装置，系统和亲水性聚合物海绵状结构，如CHISTOSAN方法
公开(公告)号：EP2173293A1
公开(公告)日：2010-04-14
申请号：EP08780198.1
申请日：2008-07-16
申请人： Hemcon Medical Technologies, Inc.
发明人： MCCARTHY, Simon , MCGRATH, Barbara , WINATA, Ervelyn
IPC分类号： A61F13/00
CPC分类号： A61F13/00995 , A61F13/00063 , A61F2013/00157 , A61F2013/00472 , A61F2013/00519 , A61F2013/00931 , A61L15/28 , A61L15/425 , A61L15/64 , C08L5/08
摘要： Absorbable tissue dressing assemblies are formed from hydrophilic polymer sponge structures, such as chitosan.

6. 发明公开

EP3003026A2 BIOCOMPATIBLE AND BIOABSORBABLE DERIVATIZED CHITOSAN COMPOSITIONS 有权
标题翻译：生物相容的，生物可吸收的和衍生的脱乙酰壳多糖的组合物
公开(公告)号：EP3003026A2
公开(公告)日：2016-04-13
申请号：EP14770494.4
申请日：2014-03-14
申请人： Hemcon Medical Technologies, Inc.
发明人： MCGRATH, Barbara , MCCARTHY, Simon , KUHN, Sam , WOLD, Alysha , STOLTEN, Michael , BENNETT, Amanada
IPC分类号： A01N25/00
CPC分类号： A61L27/58 , A61K9/0024 , A61K47/36 , A61K49/0008 , A61L27/20 , A61L27/26 , A61L2400/04 , C08B37/003 , C08L5/08 , C08L89/06 , C08L2201/06 , G01N33/5014 , G01N33/6869 , G01N2333/545 , G01N2400/28
摘要： The invention relates to biocompatible, bioabsorbable derivatized non-crosslinked chitosan compositions optionally crosslinked to gelatin/collagen by 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride (EDC) for biomedical use and methods of making and testing such compositions, including a modified acute systemic toxicity test. The compositions comprise derivatized chitosan reacetylated to a degree of N-deacetylation (DDA) of between about 15% and 40%. The compositions are typically bioabsorbed in about 90 days or less and can be made to bioabsorb at differing rates of speed. The compositions are initially soluble in aqueous solution below pH 6.5. The compositions have an acid content that can be adjusted between about 0% (w/w) and about 8% (w/w) to customize the composition for uses that require and/or tolerate differing levels of cytotoxicity, adhesion, composition cohesion, and cell infiltration into the composition.

7. 发明申请

WO2003004738A1 HIGH-STRENGTH CHEMICALLY RESISTANT THIN SHEATH FIBERS AND METHODS OF MANUFACTURE 审中-公开
标题翻译：高强度耐化学品薄膜纤维和制造方法
公开(公告)号：WO2003004738A1
公开(公告)日：2003-01-16
申请号：PCT/US2001/041240
申请日：2001-07-03
申请人： HONEYWELL INTERNATIONAL INC. , ZHOU, Qiang , LOBOVSKY, Alex , MATRUNICH, Jim , TWOMEY, Conor , MCGRATH, Barbara
发明人： ZHOU, Qiang , LOBOVSKY, Alex , MATRUNICH, Jim , TWOMEY, Conor , MCGRATH, Barbara
IPC分类号： D01F8/00
CPC分类号： D01F8/10 , D01F8/06 , D01F8/12 , D01F8/14
摘要： Compositions and methods are directed to a sheath core fiber with a core and a sheath that comprises a fluoropolymer. Contemplated sheath materials include PVDF, ECTFE, and ETFE, and may have an apparent shear viscosity equal to or less than the apparent shear viscosity of the core material. Especially contemplated sheaths have a weight of 30% or less of the weight of the fiber. Preferred fibers are spun in a spin pack having a sheath material conduit with a ratio of open volume to sheath material mass flow of less than 0.75 for a fiber with a 30wt% sheath, of less than 1.15 for a fiber with a 20wt% sheath, and of less than 2.30 for a fiber with a 10wt% sheath.
摘要翻译：组合物和方法涉及具有包含氟聚合物的芯和鞘的皮芯纤维。考虑的护套材料包括PVDF，ECTFE和ETFE，并且可以具有等于或小于芯材料的表观剪切粘度的表观剪切粘度。特别设想的护套具有纤维重量的30％或更小的重量。优选的纤维在具有护套材料管道的纺丝组件中旋转，对于具有30重量％护套的纤维，具有20重量％护套的纤维的小于1.15的开口体积与护套材料质量流量的比率小于0.75，对于具有10重量％护套的纤维，小于2.30。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式