专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2017197016A1 MELATONIN-BASED NASAL COMPOSITIONS AND USES THEREOF 审中-公开
标题翻译：基于褪黑素的鼻用组合物及其用途
公开(公告)号：WO2017197016A1
公开(公告)日：2017-11-16
申请号：PCT/US2017/032008
申请日：2017-05-10
申请人： THE LESTER SMITH MEDICAL RESEARCH INSTITUTE, LLC
发明人： CORONADO, Ramon
IPC分类号： A61K9/00 , A61K31/4045 , A61K31/405 , A61P25/20
摘要： Disclosed is an improved composition characterized in containing a combination of melatonin and 5-HTP in a nasal administration for the rapid treatment of insomnia, anxiety, and related disorders in mammals, including humans. The present invention relates also to a pharmaceutical composition comprising 5-HTP and melatonin which utilizes the known effects of two substances to provide sleep improvement, relaxation, and reduced anxiety via rapid delivery of the combination, via nasal administration, for short-term alleviation of sleep disorder and anxiety-related symptoms. The combined effects of 5-HTP and melatonin in the present invention provide a short-term increase in blood plasma levels of melatonin while simultaneously increasing the production of serotonin for purposes of achieving natural melatonin biosynthesis in combination with the increased melatonin content in blood plasma.
摘要翻译：公开了一种改进的组合物，其特征在于在鼻腔施用中含有褪黑激素和5-HTP的组合，用于快速治疗哺乳动物包括人的失眠，焦虑和相关病症。本发明还涉及包含5-HTP和褪黑激素的药物组合物，其利用两种物质的已知作用通过经鼻施用快速递送组合以提供睡眠改善，松弛和减轻的焦虑，用于短期缓解睡眠障碍和焦虑相关症状。本发明中5-HTP和褪黑激素的联合作用提供了褪黑激素的血浆水平的短期增加，同时增加了血清素的产生，以实现天然褪黑激素生物合成并结合血浆中褪黑激素含量的增加。

IPRDB

热门服务

关于我们

友情链接

联系方式