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1. 发明授权

US09018381B2 Chemical compounds 有权
标题翻译：化合物
公开(公告)号：US09018381B2
公开(公告)日：2015-04-28
申请号：US13198764
申请日：2011-08-05
申请人： Robert Bruce Diebold , Thomas Gero , Paul Grover , Shan Huang , Stephanos Ioannidis , Claude Afona Ogoe , Jamal Carlos Saeh
发明人： Robert Bruce Diebold , Thomas Gero , Paul Grover , Shan Huang , Stephanos Ioannidis , Claude Afona Ogoe , Jamal Carlos Saeh
IPC分类号： C07D211/30 , A61K31/445 , C07D211/34 , C07F9/59 , C07D413/12 , C07D211/22
CPC分类号： C07F9/65583 , A61K31/451 , A61K31/496 , A61K31/5377 , A61K31/675 , C07D211/22 , C07D211/34 , C07D413/12 , C07F9/58 , C07F9/59 , C07F9/650952
摘要： The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.
摘要翻译：本发明涉及式（I）的化合物及其盐，药物组合物，使用方法及其制备方法。这些化合物抑制Bcl-2和/或Bcl-XL活性，并可用于治疗癌症。

2. 发明授权

US08793714B2 Excluding specific application traffic from customer consumption data 有权
标题翻译：从客户消费数据中排除特定的应用流量
公开(公告)号：US08793714B2
公开(公告)日：2014-07-29
申请号：US13342727
申请日：2012-01-03
申请人： Michael S. Kelsen , Tushar Nakhre , Shan Huang , Andrew Danforth , Howard Pfeffer
发明人： Michael S. Kelsen , Tushar Nakhre , Shan Huang , Andrew Danforth , Howard Pfeffer
IPC分类号： H04N7/16 , H04N7/173
CPC分类号： H04N21/2543 , H04L12/1435 , H04L12/1485 , H04M15/41 , H04M15/60 , H04M15/8214 , H04N21/2541 , H04N21/25841 , H04N21/262 , H04N21/266 , H04N21/42684 , H04N21/4622 , H04N21/6118 , H04N21/6125 , H04N21/6168 , H04N21/6175 , H04N21/6402 , H04N21/64322
摘要： Techniques disclosed herein include systems and methods for excluding specific application traffic from customer consumption-based data billing counts. This is useful for excluding traffic from consumption totals where the application traffic has been accounted for using other means, such as through billing as a separate or technically distinct service. In practice, a tablet computer (or other end user device) can run a video application that uses a high-speed data network via a cable modem. This video application may be included as part of a core video package associated with a distinct cable television service. The system then provides accurate consumption billing of customer traffic that is outside of any other managed services by creating separate logical data service flows at a Cable Modem Termination System (CMTS) for excluding specific traffic counts.
摘要翻译：本文公开的技术包括用于将特定应用流量从基于消费者消费的数据计费计数中排除的系统和方法。这有助于排除使用其他方式计算应用程序流量的消费总量的流量，例如通过单独或技术上不同的服务计费。实际上，平板电脑（或其他最终用户设备）可以运行通过电缆调制解调器使用高速数据网络的视频应用程序。该视频应用可以被包括为与不同的有线电视服务相关联的核心视频包的一部分。然后，系统通过在有线调制解调器终端系统（CMTS）上创建单独的逻辑数据服务流来提供不在任何其他管理服务之外的客户流量的精确消费计费，以排除特定流量计数。

3. 发明申请

US20110201628A1 HETEROCYCLIC JAK KINASE INHIBITORS 审中-公开
标题翻译：异源JAK激酶抑制剂
公开(公告)号：US20110201628A1
公开(公告)日：2011-08-18
申请号：US13119028
申请日：2009-09-29
申请人： Claudio Edmundo Chuaqui , Shan Huang , Stephanos Ioannidis , Jie Shi , Mei Su , Qibin Su
发明人： Claudio Edmundo Chuaqui , Shan Huang , Stephanos Ioannidis , Jie Shi , Mei Su , Qibin Su
IPC分类号： A61K31/519 , C07D491/04 , C07D487/04 , C07D471/04 , C07D239/70 , C07D239/72 , A61K31/517 , A61P35/00
CPC分类号： C07D495/04 , C07D403/14 , C07D471/04 , C07D487/04 , C07D513/04
摘要： The present invention relates to compounds of Formula (I) and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds provide a treatment for myeloproliferative disorders and cancer.
摘要翻译：本发明涉及式（I）化合物及其盐，药物组合物，使用方法及其制备方法。这些化合物提供骨髓增生性疾病和癌症的治疗。

4. 外观设计

USD980907S1 Clipboard 有权
公开(公告)号：USD980907S1
公开(公告)日：2023-03-14
申请号：US29848210
申请日：2022-07-31
申请人： Shan Huang
设计人： Shan Huang , Guorong Xu

5. 发明申请

US20130310344A1 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS 审中-公开
标题翻译： N-氨基磺酰胺疫苗促进剂
公开(公告)号：US20130310344A1
公开(公告)日：2013-11-21
申请号：US13814318
申请日：2011-08-05
申请人： Robert Bruce Diebold , Thomas Gero , Paul Grover , Shan Huang , Stephanos Ioannidis , Claude Afona Ogoe , Jamal Carlos Saeh , Jeffrey Gilbert Varnes
发明人： Robert Bruce Diebold , Thomas Gero , Paul Grover , Shan Huang , Stephanos Ioannidis , Claude Afona Ogoe , Jamal Carlos Saeh , Jeffrey Gilbert Varnes
IPC分类号： C07D211/34 , C07F9/59 , C07D413/12
CPC分类号： C07F9/65583 , A61K31/451 , A61K31/496 , A61K31/5377 , A61K31/675 , C07D211/22 , C07D211/34 , C07D413/12 , C07F9/58 , C07F9/59 , C07F9/650952
摘要： The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.
摘要翻译：本发明涉及式（I）的化合物及其盐，药物组合物，使用方法及其制备方法。这些化合物抑制Bcl-2和/或Bcl-XL活性，并可用于治疗癌症。

6. 发明申请

US20110046400A1 PREPARATION METHOD OF (3S,4S)-3-HEXYL-4-((R)-2-HYDROXYTRIDECYL)-OXETAN-2-0NE AND THE PRODUCT OF THAT METHOD 有权
标题翻译：（3S，4S）-3-甲基-4 - （（R）-2-羟基吡啶基） - 异-2-烯的制备方法及其制法
公开(公告)号：US20110046400A1
公开(公告)日：2011-02-24
申请号：US12990111
申请日：2008-05-26
申请人： Yong Qin , Xianglin Deng , Xuan Zhou , Guofeng Yu , Ke Wang , Hao Song , Xiaolin Wang , Shan Huang
发明人： Yong Qin , Xianglin Deng , Xuan Zhou , Guofeng Yu , Ke Wang , Hao Song , Xiaolin Wang , Shan Huang
IPC分类号： C07D305/12
CPC分类号： C07D305/12 , C07D213/70
摘要： The present invention relates to a method for the preparation of (3S,4S)-3-hexyl-4-((R)-2-hydroxytridecyl)-oxetan-2-one and a product of the method. The method includes the following steps: a) reducing a substance represented by formula (II) to obtain a substance represented by formula (III), and then oxidizing the substance represented by formula (III) to form a substance represented by formula (IV); b) acylating n-octanoic acid to obtain n-octanoyl chloride using thionyl dichloride, then condensing the obtained n-octanoyl chloride with 2-mercapto-pyridine under basic condition to form a substance represented by formula (V), and then converting the substance represented by formula (V) to a substance represented by formula (VI); c) reacting the substance obtained in the step a) with the substance obtained in the step b) under catalytic condition of Lewis acid to generate a substance represented by formula (VII), and then reacting with a Lewis acid. The meanings of the signs in these formulas are the same as those in the description.
摘要翻译：本发明涉及制备（3S，4S）-3-己基-4 - （（R）-2-羟基十三烷基）氧杂环丁烷-2-酮的方法和该方法的产物。该方法包括以下步骤：a）还原由式（II）表示的物质以获得由式（III）表示的物质，然后氧化由式（III）表示的物质以形成由式（IV）表示的物质， ; b）用正辛酸酰化得到正辛酰氯，然后在碱性条件下将所得的正辛酰氯与2-巯基 - 吡啶缩合形成式（Ⅴ）表示的物质，然后转化成物质由式（Ⅴ）代表由式（Ⅵ）表示的物质; c）在路易斯酸的催化条件下，使步骤a）中获得的物质与步骤b）中获得的物质反应，生成由式（Ⅶ）表示的物质，然后与路易斯酸反应。这些公式中的符号的含义与描述中的符号的含义相同。

7. 发明授权

US09465198B2 Optical imaging lens and electronic device comprising the same 有权
标题翻译：光学成像透镜及其组成的电子设备
公开(公告)号：US09465198B2
公开(公告)日：2016-10-11
申请号：US14695049
申请日：2015-04-24
申请人： Shih-Han Chen , Huabin Liao , Shan Huang
发明人： Shih-Han Chen , Huabin Liao , Shan Huang
IPC分类号： G02B3/02 , G02B13/18 , G02B9/62 , G02B13/00 , H04N5/225 , G02B3/04 , G02B9/64 , G02B5/00 , G02B27/00
摘要： An optical imaging lens set includes an aperture stop, a first lens element to a sixth lens element from an object side toward an image side along an optical axis. The first lens element has an image-side surface with a convex portion in a vicinity of its periphery. The second lens element has an image-side surface with a concave portion in a vicinity of the optical axis and a convex portion in a vicinity of its periphery. The third lens element is made of plastic. The fourth lens element has an image-side surface with a concave portion in a vicinity of its periphery. The fifth lens element is made of plastic. The sixth lens element is made of plastic and has an object-side surface with a concave portion in a vicinity of the optical axis.
摘要翻译：光学成像透镜组包括孔径光阑，第一透镜元件，沿着光轴从物体侧朝向像侧的第六透镜元件。第一透镜元件具有在其周边附近具有凸部的图像侧表面。第二透镜元件具有在光轴附近具有凹部的像侧表面和其周边附近的凸部。第三透镜元件由塑料制成。第四透镜元件具有在其周边附近具有凹部的图像侧表面。第五透镜元件由塑料制成。第六透镜元件由塑料制成，并且具有在光轴附近具有凹部的物体侧表面。

8. 发明授权

US08931073B2 Firewall access control with border gateway protocol attributes 有权
标题翻译：具有边界网关协议属性的防火墙访问控制
公开(公告)号：US08931073B2
公开(公告)日：2015-01-06
申请号：US13237678
申请日：2011-09-20
申请人： Shan Huang , Michael S. Kelsen , Ron da Silva
发明人： Shan Huang , Michael S. Kelsen , Ron da Silva
IPC分类号： H04L29/06 , H04L12/56 , H04L12/715
CPC分类号： H04L45/04 , H04L63/0227 , H04L63/0236
摘要： Packets are routed from at least one internet protocol (IP) address in accordance with border gateway protocol (BGP); while carrying out the routing in accordance with the border gateway protocol (BGP), at least one border gateway protocol (BGP) attribute associated with the at least one internet protocol (IP) address is noted. A firewall policy is applied to the packets from the at least one internet protocol (IP) address based on the at least one border gateway protocol (BGP) attribute associated with the at least one internet protocol (IP) address. Techniques may be implemented, for example, on a router or on a separate firewall device coupled to a router.
摘要翻译：数据包根据边界网关协议（BGP）从至少一个互联网协议（IP）地址路由; 在根据边界网关协议（BGP）执行路由的同时，指出与所述至少一个因特网协议（IP）地址相关联的至少一个边界网关协议（BGP）属性。基于与至少一个因特网协议（IP）地址相关联的至少一个边界网关协议（BGP）属性，将防火墙策略应用于来自所述至少一个因特网协议（IP）地址的分组。技术可以例如在路由器上或耦合到路由器的单独的防火墙设备上实现。

9. 发明授权

US08885667B2 Destination based methodology for managing network resources 有权
标题翻译：用于管理网络资源的基于目标的方法
公开(公告)号：US08885667B2
公开(公告)日：2014-11-11
申请号：US12500751
申请日：2009-07-10
申请人： Ron da Silva , Shan Huang , Michael S. Kelsen
发明人： Ron da Silva , Shan Huang , Michael S. Kelsen
IPC分类号： H04L12/801 , H04L12/823 , H04L12/851 , H04L12/413 , H04L12/927 , H04L12/813
CPC分类号： H04L47/10 , H04L12/413 , H04L47/12 , H04L47/20 , H04L47/2441 , H04L47/32 , H04L47/808
摘要： A replicator is configured to be coupled to a first packet-based network, and a packet analysis module and a router are coupled to the replicator. The router is configured to be coupled to a second packet-based network. The replicator receives packets from the first packet-based network, passes the packets to the router, and passes a copy of the packets to the packet analysis module. The packet analysis module identifies, in a set of customers of the second packet-based network, a top usage subset. The top usage subset includes those of the customers who are using more bandwidth of the second packet-based network than other ones of the customers. The top usage subset includes at least two of the customers. The packet analysis module identifies, at an entry point of the second packet-based network, routes of packets destined for the top usage subset. The router discards a predetermined percentage of the packets destined for the top usage subset. The predetermined percentage is determined in order to reduce bandwidth utilization of the second packet-based network by a desired amount. The predetermined percentage is identical for all of the customers in the top usage subset.
摘要翻译：复制器被配置为耦合到第一基于分组的网络，并且分组分析模块和路由器耦合到复制器。路由器被配置为耦合到第二基于分组的网络。复制器从第一个基于分组的网络接收分组，将分组传递给路由器，并将分组的副本传递给分组分析模块。分组分析模块在第二基于分组的网络的一组客户中识别顶部使用子集。最大的使用子集包括那些正在使用第二个基于分组的网络的带宽比其他客户的客户的那些。最高使用量子集包括至少两个客户。分组分析模块在第二基于分组的网络的入口点处识别去往顶部使用子集的分组的路由。路由器丢弃目的地为最大使用子集的预定百分比的分组。确定预定百分比以便将第二基于分组的网络的带宽利用率减少期望的量。对于最高使用子集中的所有客户，预定百分比是相同的。

10. 发明申请

US20130074174A1 FIREWALL ACCESS CONTROL WITH BORDER GATEWAY PROTOCOL ATTRIBUTES 有权
标题翻译：使用边界网关协议属性进行防火墙访问控制
公开(公告)号：US20130074174A1
公开(公告)日：2013-03-21
申请号：US13237678
申请日：2011-09-20
申请人： Shan Huang , Michael S. Kelsen , Ron Da Silva
发明人： Shan Huang , Michael S. Kelsen , Ron Da Silva
IPC分类号： G06F21/20
CPC分类号： H04L45/04 , H04L63/0227 , H04L63/0236
摘要： Packets are routed from at least one internet protocol (IP) address in accordance with border gateway protocol (BGP); while carrying out the routing in accordance with the border gateway protocol (BGP), at least one border gateway protocol (BGP) attribute associated with the at least one internet protocol (IP) address is noted. A firewall policy is applied to the packets from the at least one internet protocol (IP) address based on the at least one border gateway protocol (BGP) attribute associated with the at least one internet protocol (IP) address. Techniques may be implemented, for example, on a router or on a separate firewall device coupled to a router.
摘要翻译：数据包根据边界网关协议（BGP）从至少一个互联网协议（IP）地址路由; 在根据边界网关协议（BGP）执行路由的同时，指出与所述至少一个因特网协议（IP）地址相关联的至少一个边界网关协议（BGP）属性。基于与至少一个因特网协议（IP）地址相关联的至少一个边界网关协议（BGP）属性，将防火墙策略应用于来自所述至少一个因特网协议（IP）地址的分组。技术可以例如在路由器上或耦合到路由器的单独的防火墙设备上实现。

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