专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 外观设计

USD969536S1 Pot cover stand 有权
公开(公告)号：USD969536S1
公开(公告)日：2022-11-15
申请号：US29727922
申请日：2020-03-13
申请人： Shuisheng Ye , Bo Zhang
设计人： Shuisheng Ye , Bo Zhang

2. 外观设计

USD960637S1 Simple push-button lid with straw 有权
公开(公告)号：USD960637S1
公开(公告)日：2022-08-16
申请号：US29802097
申请日：2021-08-03
申请人： Bo Zhang
设计人： Bo Zhang

3. 外观设计

USD946347S1 Vacuum bottle lid with handle 有权
公开(公告)号：USD946347S1
公开(公告)日：2022-03-22
申请号：US29774305
申请日：2021-03-16
申请人： Bo Zhang
设计人： Bo Zhang

4. 发明申请

US20170258940A1 TRANSGENIC MOUSE MODEL FOR CONDITIONAL FKBP51 EXPRESSION AND RELATED METHODS 审中-公开
公开(公告)号：US20170258940A1
公开(公告)日：2017-09-14
申请号：US15602985
申请日：2017-05-23
申请人： Chad Dickey , Bo Zhang , Laura Jenelle Blair
发明人： Chad Dickey , Bo Zhang , Laura Jenelle Blair
IPC分类号： A61K49/00 , A01K67/027 , C12N15/85 , C12N9/90
CPC分类号： A61K49/0006 , A01K67/0278 , A01K2217/203 , A01K2227/105 , A01K2267/01 , A01K2267/0356 , A61K49/0008 , C12N9/90 , C12N15/8509
摘要： The subject invention pertains to transgenic non-human animals comprising a transgenic nucleotide sequence, integrated into the genome of the animals, comprising a nucleotide sequence encoding human FKBP51 operably linked to a tetracycline response element. In some embodiments, the transgenic animal comprises an additional transgenic nucleotide sequence, integrated into the genome of the animal, comprising a nucleotide sequence encoding a tetracycline transactivator (tTA) operably linked to a promoter; wherein the tTA is expressed upon activation of the promoter and binds the tetracycline response element, thereby causing expression of FKBP51. The invention also pertains to methods for screening for agents for the prevention and/or treatment of psychiatric disorders, such as depression.

5. 发明授权

US09453062B2 Glucose dependent insulinotropic polypeptide analogs, pharmaceutical compositions and use thereof 有权
标题翻译：葡萄糖依赖性促胰岛素多肽类似物，药物组合物及其用途
公开(公告)号：US09453062B2
公开(公告)日：2016-09-27
申请号：US14125061
申请日：2012-06-08
申请人： Tao Ma , Shusen Xu , Zhijun Liu , Bo Zhang , Ning Shen , Hai Yang , Wei Zhang , Yuhua Li , Sunghwan Moon , Maengsup Kim
发明人： Tao Ma , Shusen Xu , Zhijun Liu , Bo Zhang , Ning Shen , Hai Yang , Wei Zhang , Yuhua Li , Sunghwan Moon , Maengsup Kim
IPC分类号： A61K38/22 , A61K38/00 , A61K38/28 , A61K38/26 , A61K38/16 , A61P3/04 , A61P3/10 , A61P7/12 , A61P19/10 , C07K14/605 , C07K5/00 , C07K7/00 , C07K16/00 , C07K17/00 , C07K14/575 , C07K14/00
CPC分类号： C07K14/575 , A61K38/00 , A61K38/16 , A61K38/22 , C07K14/00 , C07K14/605
摘要： The present invention provides a GIP analog, which is derived from GIP (1-29, SEQ ID NO: 1), has both GLP-1 agonist activity and GIPR stimulation activity, and comprises an amino acid sequence represented by the following formula I: Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp-Leu- A27-A28-A29-Y. The present invention also provides a pharmaceutical composition comprising the GIP analog and use thereof.
摘要翻译：本发明提供衍生自GIP（1-29，SEQ ID NO：1）的GIP类似物具有GLP-1激动剂活性和GIPR刺激活性，并且包含由下式I表示的氨基酸序列： Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp- Leu- A27-A28-A29-Y。本发明还提供了包含GIP类似物及其用途的药物组合物。

6. 发明申请

US20150231238A1 OVERCOMING RESISTANCE TO ERBB PATHWAY INHIBITORS 审中-公开
标题翻译：对ERBB途径抑制剂的抵抗力
公开(公告)号：US20150231238A1
公开(公告)日：2015-08-20
申请号：US14004848
申请日：2012-03-15
申请人： Gabriela Garcia , William Kubasek , Maria Johanna Lahdenranta , Gavin MacBeath , Charlotte McDonagh , Victor Moyo , Matthew David Onsum , Birgit Schoeberl , Mark Sevecka , Marisa Wainszelbaum , Bo Zhang
发明人： Gabriela Garcia , William Kubasek , Maria Johanna Lahdenranta , Gavin MacBeath , Charlotte McDonagh , Victor Moyo , Matthew David Onsum , Birgit Schoeberl , Mark Sevecka , Marisa Wainszelbaum , Bo Zhang
IPC分类号： A61K39/395 , A61K45/06 , A61K31/138 , A61K31/337
CPC分类号： A61K39/39558 , A61K31/138 , A61K31/337 , A61K31/513 , A61K31/517 , A61K31/7068 , A61K33/24 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/55 , C07K16/2863 , C07K16/32 , C07K2317/31 , C07K2317/73 , C07K2317/76 , A61K2300/00
摘要： Provided are methods for overcoming resistance to an ErbB pathway inhibitor, such as an EGFR inhibitor or a HER2 inhibitor. The resistance may be acquired resistance to an EGFR inhibitor, such as acquired resistance to gefitinib. In the methods provided, a subject exhibiting resistance to an ErbB pathway inhibitor is selected and both an ErbB 3 inhibitor and a second ErbB pathway inhibitor are administered to the subject, such as an EGFR inhibitor or a HER2 inhibitor. Also provided are methods for inhibiting the growth of a tumor comprising a T790M EGFR mutation by contacting the tumor with an ErbB3 inhibitor and an EGFR inhibitor. Compositions for overcoming resistance to an ErbB pathway inhibitor, comprising both an ErbB 3 inhibitor and a second ErbB pathway inhibitor, such as an EGFR inhibitor or a HER2 inhibitor, are also provided.
摘要翻译：提供了克服对ErbB途径抑制剂如EGFR抑制剂或HER2抑制剂的抗性的方法。抗性可能是对EGFR抑制剂的获得性抗性，如对吉非替尼的获得性抗性。在所提供的方法中，选择表现出对ErbB途径抑制剂的抗性的受试者，并且对受试者，例如EGFR抑制剂或HER2抑制剂施用ErbB 3抑制剂和第二ErbB途径抑制剂。还提供了通过使肿瘤与ErbB3抑制剂和EGFR抑制剂接触来抑制包含T790M EGFR突变的肿瘤的生长的方法。还提供了克服对ErbB通路抑制剂的抗性的组合物，其包含ErbB 3抑制剂和第二ErbB途径抑制剂，例如EGFR抑制剂或HER2抑制剂。

7. 发明申请

US20150121536A1 METHODS AND APPARATUS FOR PROTECTING SOFTWARE FROM UNAUTHORIZED COPYING 有权
标题翻译：用于从未经授权的复制保护软件的方法和装置
公开(公告)号：US20150121536A1
公开(公告)日：2015-04-30
申请号：US14125743
申请日：2013-10-24
申请人： Bin Xing , Bo Zhang , Mark W. Shanahan , James D. Beaney, JR.
发明人： Bin Xing , Bo Zhang , Mark W. Shanahan , James D. Beaney, JR.
IPC分类号： G06F21/12 , G06F21/53
CPC分类号： G06F21/12 , G06F21/53 , G06F2221/03 , G06F2221/07
摘要： A processing device provides a method for protecting a program from unauthorized copying. The processing device may include an encrypted version of the program. According to one example method, the processing device creates a secure enclave, and in response to a request to execute the encrypted program, the processing device automatically generates a decrypted version of the program in the secure enclave by decrypting the encrypted program in the secure enclave. After automatically generating the decrypted version of the program in the secure enclave, the processing device may automatically execute the decrypted version of the program in the secure enclave. Other embodiments are described and claimed.
摘要翻译：一种处理装置提供了一种保护程序免遭未经授权复制的方法。处理设备可以包括程序的加密版本。根据一个示例性方法，处理设备创建安全飞地，并且响应于执行加密程序的请求，处理设备通过解密安全飞地中的加密程序来自动地生成安全飞地中的程序的解密版本。在安全飞地自动生成程序的解密版本之后，处理装置可以自动地在安全飞地中执行程序的解密版本。描述和要求保护其他实施例。

8. 发明授权

US08983835B2 Electronic device and server for processing voice message 有权
标题翻译：用于处理语音留言的电子设备和服务器
公开(公告)号：US08983835B2
公开(公告)日：2015-03-17
申请号：US13173177
申请日：2011-06-30
申请人： Shih-Fang Wong , Tsung-Jen Chuang , Bo Zhang
发明人： Shih-Fang Wong , Tsung-Jen Chuang , Bo Zhang
IPC分类号： G10L15/00 , G10L15/26 , H04M1/64 , H04W4/12 , H04W4/18
CPC分类号： H04W4/12 , G10L15/265 , H04W4/18
摘要： An electronic device includes a voice processing unit, a wireless communication unit, and a combining unit. The voice processing unit receives speech signals. The wireless communication unit sends the speech signals to a server. The server converts the speech signals into a text message. The wireless communication unit receives the text message from the server. The combining unit combines the text message and the speech signals into a combined message. The wireless communication unit further sends the combined message to a recipient. A related server is also provided.
摘要翻译：电子设备包括语音处理单元，无线通信单元和组合单元。语音处理单元接收语音信号。无线通信单元将语音信号发送到服务器。服务器将语音信号转换为文本消息。无线通信单元从服务器接收文本消息。组合单元将文本消息和语音信号组合成组合消息。无线通信单元还将组合的消息发送到接收者。还提供了一个相关的服务器。

9. 发明授权

US08866462B2 Minimum energy point tracking buck converter 有权
标题翻译：最小能量点跟踪降压转换器
公开(公告)号：US08866462B2
公开(公告)日：2014-10-21
申请号：US13637230
申请日：2011-02-28
申请人： Ping Luo , Shaowei Zhen , Xiang Geng , Ye Zhang , Yajuan He , Bo Zhang
发明人： Ping Luo , Shaowei Zhen , Xiang Geng , Ye Zhang , Yajuan He , Bo Zhang
IPC分类号： H02M3/157 , H02M3/158 , H02M1/00
CPC分类号： H02M3/157 , H02M3/158 , H02M2001/0025
摘要： This invention involves with a low power IC (Integrated Circuit) with high energy efficiency. This invention describes a Buck converter that can track the minimum energy point of the load. It works by estimating input energy of every sensing period, taking advantage of energy consumption curve of IC in sub-threshold. Energy estimation is implemented with counting conducted pulses, while maintaining constant input energy of each pulse by regulating output voltage and ON time with digital control circuit. With digital control circuit, minimum energy point can be tracked with a lookup table stored inside. Most of this invention's control circuit is digital, with benefits of low power consumption and small chip area.
摘要翻译：本发明涉及具有高能量效率的低功率IC（集成电路）。本发明描述了可以跟踪负载的最小能量点的降压转换器。通过估计每个感测周期的输入能量，利用IC的能量消耗曲线在次阈值中起作用。通过计数传导脉冲实现能量估计，同时通过使用数字控制电路调节输出电压和导通时间来保持每个脉冲的恒定输入能量。使用数字控制电路，可以使用存储在其中的查找表来跟踪最小能量点。本发明的大多数控制电路是数字式的，具有低功耗和小芯片面积的优点。

10. 发明申请

US20140162945A1 GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE ANALOGS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF 有权
标题翻译：葡萄糖依赖性胰岛素多肽类似物，药物组合物及其用途
公开(公告)号：US20140162945A1
公开(公告)日：2014-06-12
申请号：US14125061
申请日：2012-06-08
申请人： Tao Ma , Shusen Xu , Zhijun Liu , Bo Zhang , Ning Shen , Hai Yang , Wei Zhang , Yuhua Li , Sunghwan Moon , Maengsup Kim
发明人： Tao Ma , Shusen Xu , Zhijun Liu , Bo Zhang , Ning Shen , Hai Yang , Wei Zhang , Yuhua Li , Sunghwan Moon , Maengsup Kim
IPC分类号： C07K14/575
CPC分类号： C07K14/575 , A61K38/00 , A61K38/16 , A61K38/22 , C07K14/00 , C07K14/605
摘要： The present invention provides a GIP analog, which is derived from GIP (1-29, SEQ ID NO: 1), has both GLP-1 agonist activity and GIPR stimulation activity, and comprises an amino acid sequence represented by the following formula I: Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp-Leu-A27-A28-A29-Y. The present invention also provides a pharmaceutical composition comprising the GIP analog and use thereof.
摘要翻译：本发明提供衍生自GIP（1-29，SEQ ID NO：1）的GIP类似物具有GLP-1激动剂活性和GIPR刺激活性，并且包含由下式I表示的氨基酸序列： Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp- Leu-A27-A28-A29-Y。本发明还提供了包含GIP类似物及其用途的药物组合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式