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1. 发明申请

US20140221253A1 Synthetic Antibodies 审中-公开
标题翻译：合成抗体
公开(公告)号：US20140221253A1
公开(公告)日：2014-08-07
申请号：US14198316
申请日：2014-03-05
申请人： Stephen A Johnston , Neal Woodbury , John C Chaput , Christopher W Diehnelt , Hao Yan
发明人： Stephen A Johnston , Neal Woodbury , John C Chaput , Christopher W Diehnelt , Hao Yan
IPC分类号： G01N33/543
CPC分类号： G01N33/54306 , C07K16/00 , C07K16/14 , C07K16/2881 , C07K2317/31 , C40B40/10
摘要： Methods for synthetic antibodies, methods for making synthetic antibodies, methods for identifying ligands, and related methods and reagents.
摘要翻译：合成抗体的方法，制备合成抗体的方法，鉴别配体的方法以及相关方法和试剂。

2. 发明授权

US09863938B2 Synthetic antibodies 有权
公开(公告)号：US09863938B2
公开(公告)日：2018-01-09
申请号：US14198316
申请日：2014-03-05
申请人： Stephen A Johnston , Neal Woodbury , John C Chaput , Christopher W Diehnelt , Hao Yan
发明人： Stephen A Johnston , Neal Woodbury , John C Chaput , Christopher W Diehnelt , Hao Yan
IPC分类号： C40B40/10 , G01N33/543 , C07K16/00 , C07K16/14 , C07K16/28
CPC分类号： G01N33/54306 , C07K16/00 , C07K16/14 , C07K16/2881 , C07K2317/31 , C40B40/10
摘要： Methods for synthetic antibodies, methods for making synthetic antibodies, methods for identifying ligands, and related methods and reagents.

3. 发明申请

US20110143953A1 Synthetic Antibodies 审中-公开
标题翻译：合成抗体
公开(公告)号：US20110143953A1
公开(公告)日：2011-06-16
申请号：US12445923
申请日：2007-10-16
申请人： Stephen A. Johnston , Neal Woodbury , John C. Chaput , Chris W. Diehnelt , Hao Yan
发明人： Stephen A. Johnston , Neal Woodbury , John C. Chaput , Chris W. Diehnelt , Hao Yan
IPC分类号： C40B30/04 , C07K16/00 , C40B40/10
CPC分类号： G01N33/54306 , C07K16/00 , C07K16/14 , C07K16/2881 , C07K2317/31 , C40B40/10
摘要： The present invention provides methods for synthetic antibodies, methods for making synthetic antibodies, methods for identifying ligands, and related methods and reagents.
摘要翻译：本发明提供合成抗体的方法，制备合成抗体的方法，鉴定配体的方法以及相关方法和试剂。

4. 发明申请

US20120065123A1 Synthetic Antibodies 审中-公开
标题翻译：合成抗体
公开(公告)号：US20120065123A1
公开(公告)日：2012-03-15
申请号：US13256500
申请日：2010-03-23
申请人： Stephen A. Johnston , Neal Woodbury , Christopher Diehnelt , Paul Belcher , Nidhi Gupta , Zhan-Gong Zhao , Matthew Greving , Jack Emery , Hao Yan , John Chaput
发明人： Stephen A. Johnston , Neal Woodbury , Christopher Diehnelt , Paul Belcher , Nidhi Gupta , Zhan-Gong Zhao , Matthew Greving , Jack Emery , Hao Yan , John Chaput
IPC分类号： A61K38/02 , C07K1/00 , C07K19/00 , C40B20/00 , C40B20/08
CPC分类号： G01N33/6845 , C07K2318/20 , G01N33/6854 , G01N2500/04
摘要： Methods for synthetic antibodies, methods for making synthetic antibodies, methods for identifying ligands, and related methods and reagents.
摘要翻译：合成抗体的方法，制备合成抗体的方法，鉴别配体的方法以及相关方法和试剂。

5. 发明申请

US20140252316A1 QUANTUM DOTS, RODS, WIRES, SHEETS, AND RIBBONS, AND USES THEREOF 有权
标题翻译：量子，线，线，片和RIBBONS及其用途
公开(公告)号：US20140252316A1
公开(公告)日：2014-09-11
申请号：US14238775
申请日：2012-10-03
申请人： Hao Yan , Zhengtao Deng , Yan Liu
发明人： Hao Yan , Zhengtao Deng , Yan Liu
IPC分类号： H01L29/06 , H01L29/775 , H01L29/66
CPC分类号： C09K11/883 , B82Y5/00 , B82Y10/00 , B82Y15/00 , B82Y30/00 , B82Y40/00 , C01B19/002 , C01B19/007 , C01G9/08 , C01G19/00 , C01P2002/72 , C01P2002/84 , C01P2002/85 , C01P2004/04 , C01P2004/16 , C01P2004/17 , C01P2004/64 , C01P2004/86 , C01P2004/88 , C09K11/02 , C09K11/08 , C09K11/0811 , C09K11/54 , C09K11/565 , C09K11/574 , C09K11/661 , G01N33/588 , H01B1/02 , H01L29/0669 , H01L29/122 , H01L29/127 , H01L29/22 , H01L29/66977 , H01L29/775 , Y10T428/12431 , Y10T428/294
摘要： Described are ZnxCd1-xSySe1-y/ZnSzSe1-z core/shell nanocrystals, CdTe/CdS/ZnS core/shell/shell nanocrystals, optionally ally doped Zn(S,Se,Te) nano- and quantum wires, and SnS quantum sheets or ribbons, methods for making the same, and their use in biomedical and photonic applications, such as sensors for analytes in cells and preparation of field effect transistors.
摘要翻译：描述了ZnxCd1-xSySe1-y / ZnSzSe1-z核/壳纳米晶体，CdTe / CdS / ZnS核/壳/壳纳米晶体，任选地掺杂Zn（S，Se，Te）纳米和量子线，以及SnS量子片或丝带，制造方法，以及它们在生物医学和光子应用中的应用，如细胞中分析物的传感器和场效应晶体管的制备。

6. 发明申请

US20120072432A1 FACET-BASED FILTERING OF SOCIAL NETWORK UPDATE DATA 有权
标题翻译：基于FACET的社会网络更新数据的过滤
公开(公告)号：US20120072432A1
公开(公告)日：2012-03-22
申请号：US13237844
申请日：2011-09-20
申请人： Alejandro Crosa , Esteban Kozak , Yasuhiro Matsuda , Xiaoyang Gu , Hao Yan , John Wang , Chanh Nguyen
发明人： Alejandro Crosa , Esteban Kozak , Yasuhiro Matsuda , Xiaoyang Gu , Hao Yan , John Wang , Chanh Nguyen
IPC分类号： G06F17/30 , G06F15/16
CPC分类号： G06Q50/01 , G06F17/30867 , G06Q10/00
摘要： A network update interface is presented to a user on a network to display network updates from other users of a mutual social-networking site. The network updates shared by the other users are gathered in a stream and supplied to a facet-filtering system including a network update interface. The user controls the display of certain network update items according to facet-filter characteristics enabled in facet-filter selection panels in the network update interface. The facet-filter characteristics are used by a facet filter to select certain network updates for display to the user in the network update interface. Trending links to further articles with content corresponding to the facet-filter characteristics are displayed to the user according to greatest popularity among the other users. Links to the profiles of the users sharing the articles are also provided in the network update interface.
摘要翻译：向网络上的用户呈现网络更新界面以显示来自相互社交网站的其他用户的网络更新。由其他用户共享的网络更新集中在一个流中，并提供给包括网络更新界面的构面过滤系统。用户根据网络更新界面中的小平面过滤器选择面板中启用的特征滤波器特征来控制某些网络更新项目的显示。小平面滤波器特征由小平面滤波器用于选择某些网络更新以在网络更新界面中向用户显示。根据其他用户的最大的普及程度，向用户显示与具有相关特征的内容对应的其他文章的趋势链接。在网络更新界面中还提供了共享文章用户的配置文件的链接。

7. 发明申请

US20100318397A1 SYNCHRONIZING DELEGATION MODELS BETWEEN DISPARATE SERVERS 审中-公开
标题翻译：同步服务器之间的同步代码模型
公开(公告)号：US20100318397A1
公开(公告)日：2010-12-16
申请号：US12483245
申请日：2009-06-12
申请人： Vishal Singh , Murtaza H. Hakim , Hao Yan , Nishant P. Choudhary , Vijay Kishen Hampapur Parthasarathy , Amit Gupta , Dhigha D. Sekaran
发明人： Vishal Singh , Murtaza H. Hakim , Hao Yan , Nishant P. Choudhary , Vijay Kishen Hampapur Parthasarathy , Amit Gupta , Dhigha D. Sekaran
IPC分类号： G06Q10/00 , H04L29/06 , G06F15/16 , G06Q50/00
CPC分类号： H04L67/1095 , G06Q10/10 , G06Q10/105 , G06Q10/1093 , H04L12/1818 , H04L67/325
摘要： Architecture that provides synchronization of delegation permissions between discrete delegation models. For example, the synchronization of the delegation permissions (of a delegator and delegatee) can be performed between a delegation component of a scheduling system and a delegation component of a conferencing system such that the delegatee not only accesses the scheduling system on behalf of the delegator but also the conferencing system on behalf of the delegator. A synchronization component synchronizes the delegation permissions between the server systems (delegation components). Once synchronized, the delegatee administers the communications session, based on on-behalf-of information is validated, the delegatee can then establish the communications session.
摘要翻译：提供离散委托模型之间委派权限同步的架构。例如，可以在调度系统的委派组件和会议系统的委派组件之间执行授权委托和代理委托权限的同步，以便委托人不仅代表委托人访问调度系统也是代表委托者的会议系统。同步组件同步服务器系统（委派组件）之间的委派权限。一旦同步，委托人就管理通信会话，根据代表信息进行验证，代表可以建立通信会话。

8. 发明申请

US20080223121A1 APTAMER PROBE FOR LOCATING MOLECULES AND METHOD OF USE 审中-公开
标题翻译：用于定位分子的APTAMER探针和使用方法
公开(公告)号：US20080223121A1
公开(公告)日：2008-09-18
申请号：US11948960
申请日：2007-11-30
申请人： Liyun Lin , Hao Yan , Yan Liu , Stuart Lindsay
发明人： Liyun Lin , Hao Yan , Yan Liu , Stuart Lindsay
IPC分类号： G01B5/28
CPC分类号： G01Q60/42
摘要： An atomic force microscope and a method for detecting interactions between a probe and at least one sensed agent on a scanned surface is provided. The microscope has a scanning probe with a tip that is sensitive to a property of said scanned surface; a nucleic acid aptamer tethered to the tip of the probe; and a device for simultaneously recording the displacement of said probe tip as a function of time, topographic images, and the spatial location of interactions between said probe and the at least one sensed agent on said surface.
摘要翻译：提供了一种原子力显微镜和用于检测探针与被扫描表面上的至少一个检测到的试剂之间的相互作用的方法。显微镜具有扫描探针，其具有对所述扫描表面的特性敏感的尖端; 连接到探针末端的核酸适配子; 以及用于根据时间，地形图像以及所述探针和所述表面上的所述至少一个感测到的感测剂之间的相互作用的空间位置同时记录所述探针尖端的位移的装置。

9. 发明授权

US09202867B2 Nanocrystals containing CdTe core with CdS and ZnS coatings 有权
标题翻译：含有CdTe和ZnS涂层的CdTe核的纳米晶体
公开(公告)号：US09202867B2
公开(公告)日：2015-12-01
申请号：US14238775
申请日：2012-10-03
申请人： Hao Yan , Zhengtao Deng , Yan Liu
发明人： Hao Yan , Zhengtao Deng , Yan Liu
IPC分类号： C09K11/08 , H01L29/06 , C09K11/54 , C09K11/02 , C09K11/56 , C09K11/57 , C09K11/66 , C09K11/88 , C01B19/00 , H01L29/12 , H01L29/22 , B82Y5/00 , B82Y30/00 , B82Y40/00 , C01G19/00 , G01N33/58 , H01L29/66 , H01L29/775 , B82Y10/00 , B82Y15/00
CPC分类号： C09K11/883 , B82Y5/00 , B82Y10/00 , B82Y15/00 , B82Y30/00 , B82Y40/00 , C01B19/002 , C01B19/007 , C01G9/08 , C01G19/00 , C01P2002/72 , C01P2002/84 , C01P2002/85 , C01P2004/04 , C01P2004/16 , C01P2004/17 , C01P2004/64 , C01P2004/86 , C01P2004/88 , C09K11/02 , C09K11/08 , C09K11/0811 , C09K11/54 , C09K11/565 , C09K11/574 , C09K11/661 , G01N33/588 , H01B1/02 , H01L29/0669 , H01L29/122 , H01L29/127 , H01L29/22 , H01L29/66977 , H01L29/775 , Y10T428/12431 , Y10T428/294
摘要： Described are CdTe/CdS/ZnS core/shell/shell nanocrystals, methods for making the same, and their use in biomedical and photonic applications, such as sensors for analytes in cells and preparation of field effect transistors. In particular, the disclosure provides a nanocrystal having a CdTe core, a CdS coating over the core, and a ZnS core over the CdS coating, where the nanocrystal has a photoluminescence maximum between about 650 nm and 900 nm.
摘要翻译：描述的是CdTe / CdS / ZnS核/壳/壳纳米晶体，其制备方法，以及它们在生物医学和光子学应用中的用途，例如用于细胞中分析物的传感器和制备场效应晶体管。具体地，本公开提供了具有CdTe芯，在芯上的CdS涂层和CdS涂层上的ZnS芯的纳米晶体，其中纳米晶体在约650nm和900nm之间具有最大的光致发光。

10. 发明授权

US08552167B2 Multifunctional aptamer-nucleic acid nanostructures for tumor-targeted killing 有权
标题翻译：用于肿瘤靶向杀伤的多功能适体 - 核酸纳米结构
公开(公告)号：US08552167B2
公开(公告)日：2013-10-08
申请号：US13392735
申请日：2010-10-07
申请人： Yung Chang , Hao Yan
发明人： Yung Chang , Hao Yan
IPC分类号： C07H21/04 , A61K48/00
CPC分类号： C12N15/115 , C12N15/10 , C12N2310/16 , C12N2310/3519
摘要： The present invention provides compositions comprising a ligand-nucleic acid nanostructure that promote tumor cell-specific killing and methods of using the compositions. Specially, the invention provides aptamer-nucleic acid nanostructures for treating tumors in a mammal. The methods of making the compositions are also provided.
摘要翻译：本发明提供了包含促进肿瘤细胞特异性杀伤的配体 - 核酸纳米结构的组合物和使用该组合物的方法。特别地，本发明提供用于治疗哺乳动物肿瘤的适体 - 核酸纳米结构。还提供了制备组合物的方法。

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