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1. 发明申请

WO1995010538A1 DNA ENCODING THE HUMAN P2U RECEPTOR AND NULL CELLS EXPRESSING P2U RECEPTORS 审中-公开
标题翻译：编码人P2U受体和表达P2U受体的空细胞的DNA
公开(公告)号：WO1995010538A1
公开(公告)日：1995-04-20
申请号：PCT/US1994011260
申请日：1994-10-04
申请人： THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL , THE CURATORS OF THE UNIVERSITY OF MISSOURI , BOUCHER, Richard, C. , WEISMAN, Gary, A. , TURNER, John, T. , HARDEN, Thomas, K. , PARR, Claude, E. , SULLIVAN, Daniel, M. , ERB, Laura, J. , LUSTIG, Kevin, D.
发明人： THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL , THE CURATORS OF THE UNIVERSITY OF MISSOURI
IPC分类号： C07K14/705
CPC分类号： C07K14/705 , A61K38/00
摘要： Isolated DNAs encoding the human P2U receptor are disclosed, along with vectors and host cells containing the same and methods of using the same. Host cells which are essentially free of endogenous P2U receptor expression, and which express a heterologous P2U receptor such as a murine P2U receptor, are also disclosed, along with methods of using the same.
摘要翻译：公开了编码人P2U受体的分离的DNA，以及含有其的载体和宿主细胞以及使用它们的方法。还公开了基本上不含内源性P2U受体表达并且表达异源P2U受体如鼠P2U受体的宿主细胞，以及使用它们的方法。

2. 发明申请

WO1991016148A1 PROCESS FOR APPLYING A COMPOSITE INSULATIVE COATING TO A SUBSTRATE 审中-公开
标题翻译：将复合绝缘涂料施用于基材的方法
公开(公告)号：WO1991016148A1
公开(公告)日：1991-10-31
申请号：PCT/US1990002087
申请日：1990-04-16
申请人： THE CURATORS OF THE UNIVERSITY OF MISSOURI
发明人： THE CURATORS OF THE UNIVERSITY OF MISSOURI , NICHOLS, Michael, F. , HAHN, Allen, W.
IPC分类号： B05D03/06
CPC分类号： B05D1/62 , B05D7/52 , H01L21/481 , H01L24/26 , H01L24/83 , H01L2224/8319 , H01L2224/8385 , H01L2924/01005 , H01L2924/01006 , H01L2924/0101 , H01L2924/01013 , H01L2924/01014 , H01L2924/01015 , H01L2924/01018 , H01L2924/01023 , H01L2924/01027 , H01L2924/01033 , H01L2924/01039 , H01L2924/01051 , H01L2924/01073 , H01L2924/01074 , H01L2924/01078 , H01L2924/01082 , H01L2924/07802 , H01L2924/09701 , H01L2924/12044 , H01L2924/14 , H01L2924/19041 , H01L2924/19042 , H01L2924/30105 , H01L2924/30107 , H01L2924/351 , H05K3/284 , H01L2924/3512 , H01L2924/00
摘要： A process for applying an adherent electrically insulative moisture-resistant composite coating to a substrate (1). A thin, adherent, highly cross-linked, substantially liquid moisture-impervious primer coating (3) is provided on the substrate (1) by glow discharge polymerization of a low molecular weight hydrocarbon monomer in a low pressure chamber containing the substrate (1), the monomer being selected from among methane, ethane, propane, ethylene, and propylene. A second polymeric coating layer (5) is provided over the primer coating (3) by glow discharge polymerization of a second precursor comprising a hydorcarbon or substituted hydrocarbon. The precursor exhibits a hydrogen yield of not greater than about 0.75 hydrogen atoms per molecule under the glow discharge polymerization conditions under which the second layer (5) is deposited, whereby the second polymeric coating layer (5) is substantially resilient and strongly bonded to the primer coating (3) and the second layer (5) comprises high concentration of surface and bulk free radicals.
摘要翻译：一种将粘附的电绝缘防潮复合涂层施加到基底（1）的方法。通过在含有基材（1）的低压室中的低分子量烃单体的辉光放电聚合，在基板（1）上提供薄的，粘附的，高度交联的，基本上液体的不透水的底漆涂层（3），所述单体选自甲烷，乙烷，丙烷，乙烯和丙烯。通过包含氢碳或取代烃的第二前体的辉光放电聚合，在底漆涂层（3）上提供第二聚合物涂层（5）。在沉积第二层（5）的辉光放电聚合条件下，前体表现出每分子不大于约0.75个氢原子的氢产率，由此第二聚合物涂层（5）基本上具有弹性并且牢固地结合到底漆涂层（3）和第二层（5）包含高浓度的表面和体积自由基。

3. 发明申请

WO1996001913A1 MONOCRYSTALLINE DIAMOND FILM PRODUCTION BY CHEMICAL VAPOR DEPOSITION 审中-公开
标题翻译：通过化学蒸气沉积生产单晶金刚石膜
公开(公告)号：WO1996001913A1
公开(公告)日：1996-01-25
申请号：PCT/US1995008630
申请日：1995-07-10
申请人： THE CURATORS OF THE UNIVERSITY OF MISSOURI
发明人： THE CURATORS OF THE UNIVERSITY OF MISSOURI , POPOVICI, Galina , CHAO, Chih-Hsiang , PRELAS, Mark, A. , CHARLSON, Joseph, E. , CHARLSON, Elaine, M. , MEESE, Jon, M. , STACY, T., E.
IPC分类号： C23C16/26
CPC分类号： C23C16/271 , C23C16/02 , C30B25/02 , C30B29/04
摘要： A monocrystalline diamond film (17) is deposited on a continous surface of a substrate (12) by a CVD process. During the nucleation and growth of diamond crystallites, a d.c. bias supplied from a d.c. bias power source (4) is applied to the substrate surface and maintained until coalescence, which results in an applied current density having a magnitude in the range of about 0.01 A/cm to about 1 A/cm .
摘要翻译：通过CVD工艺将单晶金刚石膜（17）沉积在衬底（12）的连续表面上。在金刚石微晶的成核和生长过程中，来自直流电源的偏压偏置电源（4）被施加到衬底表面并保持直到聚结，这导致施加的电流密度具有在约0.01A / cm 2至约1A / cm 2范围内的量级。

4. 发明申请

WO1995030015A2 ISOLATED EPSTEIN-BARR VIRUS BZLF2 PROTEINS THAT BIND MHC CLASS II BETA CHAINS 审中-公开
标题翻译：分离的EPSTEIN-BARR病毒BZLF2蛋白质MHC II类BETA链
公开(公告)号：WO1995030015A2
公开(公告)日：1995-11-09
申请号：PCT/US1995005348
申请日：1995-04-28
申请人： IMMUNEX CORPORATION , THE CURATORS OF THE UNIVERSITY OF MISSOURI , NATIONAL INSTITUTES OF HEALTH
发明人： IMMUNEX CORPORATION , THE CURATORS OF THE UNIVERSITY OF MISSOURI , NATIONAL INSTITUTES OF HEALTH , ALDERSON, Mark , ARMITAGE, Richard, J. , COHEN, Jeffrey, I. , COMEAU, Michael, R. , FARRAH, Theresa, M. , HUTT-FLETCHER, Lindsey, M. , SPRIGGS, Melanie, K.
IPC分类号： C12N15/62
CPC分类号： C07K16/00 , A61K38/00 , A61K39/00 , C07K14/005 , C07K16/085 , C07K2317/73 , C07K2319/00 , C12N2710/16222
摘要： Isolated viral proteins, and pharmaceutical compositions made therefrom, are disclosed which are capable of binding to a beta chain of a Class II Major Histocompatibility Complex antigen, thereby functioning to inhibit an antigen-specific response. The viral proteins also have superantigen-like activity, and inhibit EBV infection.
摘要翻译：公开了分离的病毒蛋白质和由其制备的药物组合物，其能够结合II类主要组织相容性复合物抗原的β链，从而起抑制抗原特异性应答的作用。病毒蛋白也具有超抗原样活性，并抑制EBV感染。

5. 发明申请

WO1991010456A1 MULTIPLE LUMEN CATHETER FOR HEMODIALYSIS 审中-公开
标题翻译：多发性肝细胞癌导管
公开(公告)号：WO1991010456A1
公开(公告)日：1991-07-25
申请号：PCT/US1991000071
申请日：1991-01-04
申请人： THE CURATORS OF THE UNIVERSITY OF MISSOURI
发明人： THE CURATORS OF THE UNIVERSITY OF MISSOURI , TWARDOWSKI, Zbylaut, J. , VAN STONE, John, C. , NICHOLS, W., Kirt
IPC分类号： A61M01/00
CPC分类号： A61M25/0068 , A61M1/16 , A61M1/285 , A61M1/3658 , A61M5/1582 , A61M25/0029 , A61M25/0041 , A61M2025/0031 , A61M2025/0037
摘要： A multiple lumen, intravenous catheter (10), for hemodialysis defines a distal end portion (28) in which a pair of the catheter lumens each communicates with the exterior through aperture means. By this invention the aperture means of one of the lumens defines a first port (24) at essentially the distal catheter end, and the aperture means of the other of the lumens defines a second port (26) spaced proximally along the catheter from the distal end and first port. The second port is positioned to face radially inwardly to at least a slight degree to avoid engagement of the wall of the blood vessel that the catheter occupies. Additionally, the tip of the catheter distal of the second port (26) is of substantially helically shape, being sized to assist in keeping the second port away from the blood vessel wall. The catheter may be angled or have an inflatable balloon.
摘要翻译：用于血液透析的多腔静脉内导管（10）限定了远端部分（28），其中一对导管管腔各自通过孔口装置与外部连通。通过本发明，一个管腔的孔口装置在基本上远端的导管端部限定了第一端口（24），并且另一个内腔的孔口装置限定了沿着导管从远端远侧间隔开的第二端口（26）端口和第一个端口。第二端口被定位成径向向内至少微小的程度，以避免导管占据的血管的壁的接合。此外，第二端口（26）远端的导管的尖端具有基本上螺旋形的形状，其尺寸被设计成有助于保持第二端口远离血管壁。导管可以成角度或具有可充气气囊。

6. 发明申请

WO1986006282A1 PERITONEAL DIALYSIS CATHETER 审中-公开
公开(公告)号：WO1986006282A1
公开(公告)日：1986-11-06
申请号：PCT/US1986000957
申请日：1986-04-30
申请人： THE CURATORS OF THE UNIVERSITY OF MISSOURI
发明人： THE CURATORS OF THE UNIVERSITY OF MISSOURI , TWARDOWSKI, Zbylut, J. , NOLPH, Karl, D. , KHANNA, Ramesh
IPC分类号： A61M15/00
CPC分类号： A61M1/285
摘要： A peritoneal catheter comprises a flexible catheter tube (12) carrying porous cuff means (20, 22) to facilitate permanent securance of the catheter to the abdominal wall. The catheter tube defines, in its natural, unstressed condition, a bent segment (24) adjacent the porous cuff means. This permits the catheter to be mounted in a tunnel formed through the adbominal wall in relatively unstressed configuration, with both ends pointing downwardly toward the feet of the patient. In one embodiment, the catheter includes a flange (48) extending circumferentially outwardly of the catheter tube adjacent to the porous cuff means. The flange extends at a nonperpendicular angle relative to the axis of the catheter tube, and the slope of the flange extends transverse the direction of the bent segment. The angled flange, when sutured to the posterior rectus sheath, maintains the catheter tube in the desired tunnel direction within the abdominal wall, with the distal end of the catheter tube pointed properly downwardly toward the pelvic cavity.

7. 发明申请

WO1997045027A1 THE USE OF POLYVINYLPYRROLIDONE IN FAT REDUCED COMPOSITIONS 审中-公开
标题翻译：聚氧乙烯吡咯烷酮在减少脂肪的组合物中的应用
公开(公告)号：WO1997045027A1
公开(公告)日：1997-12-04
申请号：PCT/US1997009117
申请日：1997-05-30
申请人： BASF CORPORATION , THE CURATORS OF THE UNIVERSITY OF MISSOURI
发明人： BASF CORPORATION , THE CURATORS OF THE UNIVERSITY OF MISSOURI , WOOLF, Herbert, D. , HOLLENBACH, Roger, C. , MARSHALL, Robert, T. , AMEN, Ronald, J. , CASH, Penny, A. , SNYDER, Margaret, A.
IPC分类号： A23L01/308
CPC分类号： A23G9/32 , A21D2/14 , A21D13/80 , A23C9/152 , A23G9/327 , A23L13/40 , A23L27/60 , A23L33/25
摘要： Food compositions and methods are provided for non-fat and low-fat food compositions containing a polyvinylpyrrolidone. The food compositions contain polyvinylpyrrolidone and other ingredients such as food stabilizers. Preferred compositions are non-fried foods, which include dairy products, baked goods, salad dressings, and meat products. Specific food compositions include ice cream, muffins and pourable salads.
摘要翻译：食品组合物和方法用于含有聚乙烯吡咯烷酮的非脂肪和低脂食品组合物。食品组合物含有聚乙烯吡咯烷酮和其它成分如食品稳定剂。优选的组合物是非油炸食品，其包括乳制品，烘焙食品，色拉调味品和肉制品。具体的食物组合物包括冰淇淋，松饼和可倾倒的沙拉。

8. 发明申请

WO1997038363A1 LOW OPERATING POWER, FAST-RESPONSE SERVOVALVE 审中-公开
标题翻译：低操作功率，快速响应服务器
公开(公告)号：WO1997038363A1
公开(公告)日：1997-10-16
申请号：PCT/US1997005200
申请日：1997-03-28
申请人： THE CURATORS OF THE UNIVERSITY OF MISSOURI
发明人： THE CURATORS OF THE UNIVERSITY OF MISSOURI , TAN, Jinglu
IPC分类号： G05D07/06
CPC分类号： G05D7/005 , F16K31/402 , Y10T137/7759 , Y10T137/7761 , Y10T137/7764 , Y10T137/777
摘要： A servovalve (10) includes a primary valve (18) that is movable between a closed position and a plurality of open positions in which the valve plug (60) presents a restriction of variable size for varying flow. A diaphragm (34) supports the valve plug (60). A control chamber (32) is provided on the first side of the diaphragm (34) and is connected to the inlet (14) by a pilot inlet passage (48) and to the outlet (16) by a pilot outlet passage (40). A pilot valve (20) controls the flow of fluid through the pilot outlet passage (40), and includes a control plug (82) between a closed and a plurality of open positions in which the control plug (82) presents a restriction of variable size within the pilot outlet passage (40) for varying the flow between the control chamber (32) and the outlet (16). A solenoid (94) moves the control plug (82). The plug (82) is positioned by the force of an electromagnetic coil (94) working against spring (86).
摘要翻译：伺服阀（10）包括主阀（18），其可在关闭位置和多个打开位置之间移动，其中阀塞（60）呈现可变尺寸的限制以改变流量。隔膜（34）支撑阀塞（60）。控制室（32）设置在隔膜（34）的第一侧上，并通过先导入口通道（48）连接到入口（14），并通过先导出口通道（40）连接到出口（16）。先导阀（20）控制通过先导出口通道（40）的流体流动，并且包括在闭合位置和多个打开位置之间的控制塞（82），其中控制塞（82）呈现可变的限制先导出口通道（40）内的尺寸用于改变控制室（32）和出口（16）之间的流动。螺线管（94）移动控制插头（82）。插头（82）通过对抗弹簧（86）的电磁线圈（94）的力定位。

9. 发明申请

WO1996030203A1 OPTICALLY TRANSPARENT COMPOSITE MATERIAL AND PROCESS FOR PREPARING SAME 审中-公开
标题翻译：光学透明复合材料及其制备方法
公开(公告)号：WO1996030203A1
公开(公告)日：1996-10-03
申请号：PCT/US1996003953
申请日：1996-03-20
申请人： THE CURATORS OF THE UNIVERSITY OF MISSOURI
发明人： THE CURATORS OF THE UNIVERSITY OF MISSOURI , DAY, Delbert, E. , STOFFER, James, O. , BARR, John, M.
IPC分类号： B32B05/00
CPC分类号： B29C70/086 , B29C70/20 , B29K2033/12 , B29K2309/08 , B29K2995/0026 , B29L2009/00 , B32B5/08 , B32B5/28 , C08J5/24 , C08K3/40 , Y10T428/24058 , Y10T428/24132 , Y10T428/252 , Y10T442/2992 , Y10T442/67
摘要： Glass ribbon-reinforced transparent polymer composites which provide excellent optical transparency and a low distortion level over a wide temperature range while exhibiting superior mechanical properties as compared to non-reinforced polymer counterparts, and equivalent properties as compared to glass fiber-reinforced counterparts.
摘要翻译：玻璃带状增强的透明聚合物复合材料在宽温度范围内提供优异的光学透明度和低变形水平，与非增强聚合物相比具有优异的机械性能，以及与玻璃纤维增强的对应物相当的性能。

10. 发明申请

WO1992019573A2 MULTIFUNCTIONAL LIGAND FOR USE AS A DIAGNOSTIC OR THERAPEUTIC PHARMACEUTICAL 审中-公开
标题翻译：用于诊断或治疗药物的多功能配体
公开(公告)号：WO1992019573A2
公开(公告)日：1992-11-12
申请号：PCT/US1992003662
申请日：1992-05-01
申请人： THE CURATORS OF THE UNIVERSITY OF MISSOURI , KATTI, Kattesh, V. , VOLKERT, Wynn, Arthur , KETRING, Alan, Reed
发明人： THE CURATORS OF THE UNIVERSITY OF MISSOURI
IPC分类号： C07C0
CPC分类号： A61K51/0478 , A61K51/0489 , C07F7/003 , C07F7/30 , C07F9/065 , C07F9/228 , C07F9/4496 , C07F9/5355 , C07F13/00 , C07F13/005 , C07F15/0066 , C07F15/065 , C07F19/005
摘要： A compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises either a phosphorous or germanium core and at least two hydrazine groups forming a ligand for bonding to a metal extending from the phosphorous or germanium core.
摘要翻译：制备用作治疗或诊断目的的药物的化合物和方法，所述化合物包含磷核或锗核以及至少两个配体形成肼基团附着于从磷光体或锗核延伸的金属。

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