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1. 发明授权

US09128057B2 Dual-mode microfluidic genetics testing platforms and methods of dual-mode genetics testing using same 有权
标题翻译：双模微流体遗传学测试平台和双模式遗传学检测方法
公开(公告)号：US09128057B2
公开(公告)日：2015-09-08
申请号：US13068384
申请日：2011-05-10
申请人： Tanya Moreno , Cindy Wang , David Becker
发明人： Tanya Moreno , Cindy Wang , David Becker
IPC分类号： G01N21/64 , B01L7/00
CPC分类号： G01N21/6428 , B01L7/52 , G01N21/6452 , G01N2201/061
摘要： Dual mode genetics testing systems are devised about a single element testing platform. A microfluidic network and system of interconnected receiving cells and reaction vessels supports at the same time genotyping and copy number analysis where the platform may be subject to a common thermal cycle schedule to cause the proper reactions (DNA replication) necessary in both test types. Further, the microfluidic platform which includes reaction vessels for genotyping which are spatially removed from reaction vessels for copy number analysis, is coupled to optical scanner and detection systems specifically arranged to apply test specific detection routines on each of these distinct regions or portions of the dual mode test platform.
摘要翻译：关于单个元素测试平台设计了双模式遗传学测试系统。互连接收细胞和反应容器的微流体网络和系统同时支持基因分型和拷贝数分析，其中平台可能经受常见的热循环进程，以引起两种测试类型中必需的适当反应（DNA复制）。此外，包括用于基因分型的反应容器的微流体平台被从用于拷贝数分析的反应容器中空间移除，被耦合到光学扫描器和检测系统，该系统被特别设置为在这些不同区域或双重部分的每一个上应用测试特异性检测程序模式测试平台。

2. 发明申请

US20130011832A1 Dual-mode microfluidic genetics testing platforms and methods of dual-mode genetics testing using same 有权
公开(公告)号：US20130011832A1
公开(公告)日：2013-01-10
申请号：US13068384
申请日：2011-05-10
申请人： Tanya Moreno , Cindy Wang , David Becker
发明人： Tanya Moreno , Cindy Wang , David Becker
IPC分类号： C12M1/40 , G01N21/64
CPC分类号： G01N21/6428 , B01L7/52 , G01N21/6452 , G01N2201/061
摘要： Dual mode genetics testing systems are devised about a single element testing platform. A microfluidic network and system of interconnected receiving cells and reaction vessels supports at the same time genotyping and copy number analysis where the platform may be subject to a common thermal cycle schedule to cause the proper reactions (DNA replication) necessary in both test types. Further, the microfluidic platform which includes reaction vessels for genotyping which are spatially removed from reaction vessels for copy number analysis, is coupled to optical scanner and detection systems specifically arranged to apply test specific detection routines on each of these distinct regions or portions of the dual mode test platform.

3. 发明申请

US20130164738A1 Genetic Sample Collection Systems 审中-公开
标题翻译：遗传样本收集系统
公开(公告)号：US20130164738A1
公开(公告)日：2013-06-27
申请号：US13333883
申请日：2011-12-21
申请人： David Becker , James Plante , Moreno Tanya , Cindy Wang
发明人： David Becker , James Plante , Moreno Tanya , Cindy Wang
IPC分类号： C12Q1/68 , C12M1/00
CPC分类号： B01L3/508 , A61B10/0051 , A61B10/0096 , A61B2010/0006 , B01L3/502 , B01L3/50825 , B01L99/00 , B01L2200/185 , B01L2300/042 , B01L2300/044 , B01L2300/047 , B01L2300/06 , B01L2300/0672 , C12N15/1006 , C12Q1/6806
摘要： Biological sample collection kits are devised with physical features to enable a high performance collection system which delivers preprocessed biological matter via conventional shipping means to a testing laboratories. In particular, untrained and unskilled users deposit biological matter such as saliva or blood into a receiving vessel. By sealing the container, the user causes release of a premixed solution containing preservatives and optionally lysis reagents. In addition, a purification agent is arranged to bind to target molecules and facilitate their removal from solution. These time consuming processes occur while the sample is in transit to the testing facility such that when it arrives, it is in a preconditioned state immediately ready for execution of washing steps. Thus, the high performance containers taught herein are useful for collection biological samples and performing initial process steps on received matter—steps which are largely effected during the shipping stage of the transfer process.
摘要翻译：生物样本收集套件设计有物理特征，以实现高性能收集系统，其通过常规运输方式将预处理的生物物质提供给测试实验室。特别是，未经训练和不熟练的使用者将诸如唾液或血液的生物物质沉积到接收容器中。通过密封容器，使用者引起含有防腐剂和任选裂解试剂的预混溶液的释放。此外，将净化剂配置成与靶分子结合并促进它们从溶液中的去除。这些耗时的过程发生在样品转运到测试设备时，使得当其到达时，它处于预处理状态，立即准备好执行洗涤步骤。因此，本文中教导的高性能容器对于收集生物样品是有用的，并且在接收的物质步骤上执行初始的处理步骤，这些步骤主要是在转移过程的运输阶段中实现的。

4. 发明授权

US10286297B1 Gaming table assembly 有权
公开(公告)号：US10286297B1
公开(公告)日：2019-05-14
申请号：US15920516
申请日：2018-03-14
申请人： David Becker
发明人： David Becker
IPC分类号： A63F9/04 , A63F11/00 , A63F9/06
摘要： A gaming table assembly for entertainment includes a plate and a mirror. The plate is substantially transparent. The mirror is shaped substantially complementarily to the plate. A first frame is coupled to a perimeter of the plate. A second frame is coupled to a circumference of the mirror. A plurality of legs is coupled to and extends between the first frame and the second frame. The legs are configured to support the first frame and the second frame on a horizontal surface with the first frame positioned distally from the horizontal surface and the mirror facing upwardly. A plurality of multifaceted gaming pieces is configured to position on the plate so that a respective facet of each multifaceted gaming piece is positioned in contact with the plate. The mirror is positioned to view the respective facet so that the respective facet is incorporable into a game.

5. 发明授权

US09029655B2 Cotton variety FM 9250GL 有权
标题翻译：棉花品种FM 9250GL
公开(公告)号：US09029655B2
公开(公告)日：2015-05-12
申请号：US13426694
申请日：2012-03-22
申请人： Margaret Shields , David Becker
发明人： Margaret Shields , David Becker
IPC分类号： A01H5/02 , A01H5/10
CPC分类号： A01H5/10 , A01H5/02
摘要： The cotton variety FM 9250GL is disclosed. The invention relates to seeds, plants, plant cells, plant tissue, harvested products and cotton lint as well as to hybrid cotton plants and seeds obtained by repeatedly crossing plants of variety FM 9250GL with other plants. The invention also relates to plants and varieties produced by the method of essential derivation from plants of FM 9250GL and to plants of FM 9250GL reproduced by vegetative methods, including but not limited to tissue culture of regenerable cells or tissue from FM 9250GL.
摘要翻译：棉花品种FM 9250GL被公开。本发明涉及种子，植物，植物细胞，植物组织，收获的产品和棉绒，以及通过将品种FM 9250GL的植物与其他植物重复交叉而获得的杂种棉花植物和种子。本发明还涉及通过FM 9250GL的植物必需衍生的方法生产的植物和品种以及通过营养方法再生的FM 9250GL植物，包括但不限于来自FM 9250GL的可再生细胞或组织的组织培养。

6. 发明申请

US20110289617A1 Cotton Variety FM 9103GT 有权
标题翻译：棉花品种FM 9103GT
公开(公告)号：US20110289617A1
公开(公告)日：2011-11-24
申请号：US13110425
申请日：2011-05-18
申请人： David Becker , Margaret Shields
发明人： David Becker , Margaret Shields
IPC分类号： A01H5/00 , C12N15/82 , C12N5/04 , A01H1/02 , A01H5/10 , C12N5/00
CPC分类号： A01H5/10
摘要： The cotton variety FM 9103GT is disclosed. The invention relates to seeds, plants, plant cells, plant tissue, harvested products and cotton lint as well as to hybrid cotton plants and seeds obtained by repeatedly crossing plants of variety FM 9103GT with other plants. The invention also relates to plants and varieties produced by the method of essential derivation from plants of FM 9103GT and to plants of FM 9103GT reproduced by vegetative methods, including but not limited to tissue culture of regenerable cells or tissue from FM 9103GT.
摘要翻译：棉花品种FM 9103GT被公开。本发明涉及种子，植物，植物细胞，植物组织，收获产品和棉绒，以及通过将品种FM 9103GT的植物与其他植物重复交叉而获得的杂种棉花植物和种子。本发明还涉及通过FM 9103GT的植物必需衍生的方法和通过营养方法再生的FM 9103GT的植物产生的植物和品种，包括但不限于来自FM 9103GT的可再生细胞或组织的组织培养。

7. 发明授权

US07840476B1 Transformation bidding with tooling requirements 有权
标题翻译：转型招标与工具要求
公开(公告)号：US07840476B1
公开(公告)日：2010-11-23
申请号：US10223080
申请日：2002-08-16
申请人： Matthew C. Zack , Daniel Edwards , David Becker
发明人： Matthew C. Zack , Daniel Edwards , David Becker
IPC分类号： G06Q40/00
CPC分类号： G06Q30/08 , G06Q40/04
摘要： A system and method of transformation bidding in an electronic auction system. The system acquires lot data including tooling information for a lot, receives a bid from a bidder, and transforms the lot data and the bid into a true cost of procuring the lot from the bidder. The system also presents the true cost to a sponsor.
摘要翻译：电子拍卖系统转型竞价的制度与方法。系统从批量获取包括工具信息在内的批量数据，从投标人收到投标书，并将批次数据和投标变成从投标人采购批次的真实成本。该系统还向赞助商呈现了真正的成本。

8. 发明申请

US20080037792A1 HOME NETWORK SYSTEMS 审中-公开
标题翻译：家庭网络系统
公开(公告)号：US20080037792A1
公开(公告)日：2008-02-14
申请号：US11559778
申请日：2006-11-14
申请人： David Becker , Chia Lun Chung
发明人： David Becker , Chia Lun Chung
IPC分类号： H04L9/08
CPC分类号： H04B3/542 , H04B2203/5408 , H04B2203/5445 , H04B2203/545 , H04B2203/5454 , H04L63/0428 , H04L63/062 , H04L2463/061
摘要： A method and system for key management and distribution are disclosed. A network can comprise plurality of stations, each station is dedicated to a network device and is configured to plug into an electrical receptacle so as to facilitate network communications via home electrical wiring for the network device. A hardware key is used to distribute keys among stations so as to enable access to the network for the dedicated network device. Each hardware key comprises a solid state memory. A key is stored in the solid state memory. The solid state memory is configured such that the key is not user modifiable. Thus, users cannot inadvertently delete or change the key.
摘要翻译：披露了密钥管理和分发的方法和系统。网络可以包括多个站，每个站专用于网络设备，并且被配置为插入到电插座中，以便于通过用于网络设备的家用电线来进行网络通信。硬件密钥用于在站间分配密钥，以便能够访问专用网络设备的网络。每个硬件密钥包括固态存储器。密钥存储在固态存储器中。固态存储器被配置为使得密钥不是用户可修改的。因此，用户不能无意中删除或更改密钥。

9. 发明申请

US20070037765A1 Formulations comprising antisense nucleotides to connexins 审中-公开
公开(公告)号：US20070037765A1
公开(公告)日：2007-02-15
申请号：US11447599
申请日：2006-06-05
申请人： David Becker , Colin Green
发明人： David Becker , Colin Green
IPC分类号： A61K48/00
CPC分类号： C07H21/04 , A61K31/711 , A61K38/00 , C12N15/111 , C12N15/1138 , C12N2310/11 , C12N2320/32
摘要： A therapeutic and/or cosmetic formulation comprising at least one anti-sense polynucleotide to a connexin protein together with a pharmaceutically acceptable carrier or vehicle is useful in site specific down regulation of connexin protein expression, particularly in reduction of neuronal cells death, wound healing, reduction of inflammation, decrease of scar formation and skin rejuvenation and thickening.

10. 发明授权

US08353839B2 Intracavity probe with continuous shielding of acoustic window 有权
标题翻译：具有声窗口连续屏蔽的腔内探头
公开(公告)号：US08353839B2
公开(公告)日：2013-01-15
申请号：US10599322
申请日：2005-03-22
申请人： Barry Scheirer , Kevin Wickline , David Becker , Jeffrey Hart
发明人： Barry Scheirer , Kevin Wickline , David Becker , Jeffrey Hart , Alan Hornberger
IPC分类号： A61B8/14
CPC分类号： G10K11/02
摘要： An ultrasound probe has a transducer array which is moved to scan a patient with ultrasonic energy. The array is located in a fluid chamber (42) which is enclosed by an acoustic window end cap (34). The acoustic window cap is coated with a thin conductive layer (38) which shields the transducer and its motive mechanism from EFI/RFI emissions. The conductive layer is coupled to a reference potential.
摘要翻译：超声波探头具有换能器阵列，其被移动以用超声能量扫描患者。该阵列位于由声窗端盖（34）包围的流体室（42）中。声窗盖涂覆有薄的导电层（38），其屏蔽换能器及其动力机构免受EFI / RFI发射。导电层耦合到参考电位。

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