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1. 发明专利

JP6013670B1 老化抑制剤有权
标题翻译：老化抑制剂
公开(公告)号：JP6013670B1
公开(公告)日：2016-10-25
申请号：JP2016547622
申请日：2015-12-01
申请人：株式会社日本自然発酵
发明人：東直樹 , 中西雅寛
IPC分类号： A61K36/899 , A61K36/46 , A61K36/8994 , A61K36/75 , A61K36/87 , A61K36/73 , A61K36/736 , A61K36/44 , A61K36/185 , A61K36/42 , A61K36/60 , A61K36/732 , A61K36/752 , A61K36/725 , A61K36/49 , A61K36/888 , A61K36/23 , A61K36/8962 , A61K36/39 , A61K36/894 , A61K36/31 , A61K36/28 , A61K36/896 , A61K36/9068 , A61K36/9066 , A61K36/535 , A61K36/70 , A61K36/282 , A61K36/288 , A61K36/03 , A61K36/52 , A61K36/16 , A61K36/07 , A61P39/00 , A61P43/00 , A61K36/8998
CPC分类号： A61K31/19 , A61K31/192 , A61K31/194 , A61K31/196 , A61K31/197 , A61K31/198 , A61K31/352 , A61K31/353 , A61K31/401 , A61K31/405 , A61K31/4172 , A61K35/744 , A61K36/03 , A61K36/062 , A61K36/064 , A61K36/07 , A61K36/185 , A61K36/31 , A61K36/39 , A61K36/75 , A61K36/899
摘要：本発明は、老化症状の発現を遅延させるとともに、寿命の延長をもたらし、安全性が高い老化抑制剤を提供することを課題とする。上記課題を解決した本発明の老化抑制剤は、次の(a)ないし(g) (a)大麦、黒大豆、赤米、黒米、小豆、はと麦、ヒエ、アワおよびキビよりなる群から選ばれる1種又は2種以上の豆・穀物類の麹菌発酵物 (b)ミカン、ブドウ、リンゴ、ヤマブドウ、モモ、カキ、パパイヤ、ナシ、スイカ、ウメ、イチジク、カリン、カボチャ、キンカン、ユズ、ビワ、アンズ、ナツメ、クリ、マタタビおよびスモモよりなる群から選ばれる1種又は2種以上の果実類の酵母および/又は乳酸菌発酵物 (c)紫イモ、菊芋、ニンジン、タマネギ、サツマイモ、里芋、自然薯、大根、赤カブ、ゴボウ、レンコン、ヤーコン、ユリ根、クワイ、しょうが、にんにくおよびウコンよりなる群から選ばれる1種又は2種以上の根菜類・イモ類の酵母および/又は乳酸菌発酵物 (d)キャベツ、紫蘇、桑葉、どくだみ、ヨモギ、クマザサおよびタンポポよりなる群から選ばれる1種又は2種以上の花・葉菜類の酵母および/又は乳酸菌発酵物 (e)コンブ、ワカメおよびモズクよりなる群から選ばれる1種又は2種以上の海藻類の酵母および/又は乳酸菌発酵物 (f)黒ゴマ、クルミおよびギンナンよりなる群から選ばれる1種又は2種以上の種子類の酵母および/又は乳酸菌発酵物 (g)マイタケおよびシイタケよりなる群から選ばれる1種又は2種のキノコ類の酵母および/又は乳酸菌発酵物の混合物である植物発酵物を有効成分として含有することを特徴とする。
摘要翻译：本发明中，与延迟一起的衰老症状的表达，造成生命的延长，并提供了高安全性老化抑制剂。老化的本发明解决了上述问题的抑制剂，没有如下的（a）（克）（a）中大麦，黑大豆，红米，黑米，红豆，珍珠大麦，粟，选自小米和小米一种或多种豆类，谷类的发酵曲霉选择（b）中柑桔，葡萄，苹果，葡萄coignetiae，桃，柿子，木瓜，梨，西瓜，李子，无花果，木瓜，南瓜，金桔，柚子，枇杷，杏，枣，栗子，酵母和/或选自由猕猴桃和李子（c）中紫甘薯的组中选择的一种或多种水果的乳酸菌发酵物，菊芋，胡萝卜，洋葱，甘薯，芋头，野生山药，萝卜，甜菜根，牛蒡，莲藕，雪莲果，百合，葵，姜，一个或多个根蔬菜的酵母，马铃薯选自大蒜和姜黄和/或乳酸菌发酵产物（的组中选择 D）卷心菜，紫苏桑叶，蕺草，艾蒿，一个或酵母和/或两种或更多种的花，叶蔬菜（e）中海带，选自海藻组成的组中以及从由条纹竹和蒲公英的组海蕴中选择的一种乳酸菌发酵物或酵母和/或两个或更多的海藻（f）中，黑芝麻，酵母和/或乳酸细菌选自下组的一个或多个种子包括核桃和银杏（G）的发酵产物的乳酸菌发酵物其特征在于它含有作为植物发酵产物的一种或两种活性成分是酵母和/或选自由舞茸和香菇的组中选择的蘑菇乳酸菌发酵产物的混合物。

2. 发明专利

JP5882915B2 丸葉留紅草抽出物を含有する糖尿病治療用医薬組成物有权
标题翻译：含有MaruYoTome红草提取物的抗糖尿病的药物组合物
公开(公告)号：JP5882915B2
公开(公告)日：2016-03-09
申请号：JP2012553821
申请日：2011-02-21
申请人：コリアリサーチインスティテュートオブバイオサイエンスアンドバイオテクノロジー
发明人：チョンボンヒョン , キムムニル , イソヨン , イウィジン , パクキョンスク , ペパンキ
IPC分类号： A61P3/10 , A61P9/10 , A61P9/00 , A61P13/12 , A61P27/02 , A61P43/00 , A61P13/02 , A61P35/00 , A23L33/10 , A61K36/36
CPC分类号： A61K36/39 , A23L33/105 , A23V2002/00

3. 发明专利

JP5973571B2 留紅草属から分離した新規化合物およびこれを有効成分として含む糖尿病予防または治療用組成物有权
标题翻译：新化合物和预防糖尿病或治疗组合物，其包含如从Tomebeni草属分离的活性成分
公开(公告)号：JP5973571B2
公开(公告)日：2016-08-23
申请号：JP2014525914
申请日：2012-06-28
申请人：ナノバイオテクカンパニーリミテッド , NANOBIOTECH CO., LTD.
发明人：チョンボンヒョン , イソヨン , イウィジン
IPC分类号： A61P3/10 , A61K31/715 , A61P3/06 , A61P3/04 , A61P9/10 , A61P9/00 , A61P13/12 , A61P19/02 , A61P19/10 , A61P27/02 , A61P17/02 , A61P27/06 , A61P27/12 , A61K45/00 , A61K31/198 , A61K31/4453 , A61K31/64 , A61K31/155 , A61K31/7034 , A23L33/105 , A23L2/52 , C08B37/00
CPC分类号： C08B37/006 , A23L33/40 , A61K31/351 , A61K31/715 , A61K36/39 , A61K45/06 , C07D407/12 , C07D407/14 , C07H15/04

4. 发明专利

JP2013530224A Compositions and methods to give a stimulus to the Magp-1 to improve the appearance of the skin 有权
公开(公告)号：JP2013530224A
公开(公告)日：2013-07-25
申请号：JP2013518428
申请日：2011-06-13
申请人：エイボンプロダクツインコーポレーテッド
发明人：ゼン、キアン , ダブリューチェン、シミン , サンタナム、ウマ , ダブリューライガ、ジョン
IPC分类号： A61K8/97 , A61K8/46 , A61K8/49 , A61Q19/00 , A61Q19/08
CPC分类号： A61K8/97 , A61K8/466 , A61K8/49 , A61K31/5377 , A61K36/185 , A61K36/39 , A61K36/53 , A61K36/74 , A61K45/06 , A61K2800/20 , A61Q19/00 , A61Q19/08
摘要：本開示は、皮膚の状態及び美的外観を治療、防止及び改善する方法、特に、ＭＡＧＰ−１の発現を刺激し、老化及び／又は光損傷した皮膚の外観を改善する、天然化合物又は抽出物の１種又は組み合わせたものを塗布して、皮膚の小皺及び／又は皺を治療、防止、回復、低減及び／又は除去する方法に関する。本発明の組成物は、皮膚の状態及び美的外観を改善するのに有効な量で、それを必要とする皮膚に局所的に塗布されるか、又は一定方向手段によって部位に伝達される。
【選択図】なし

5. 发明专利

JP2008208030A Inhibitor for lipid accumulation in liver 审中-公开
标题翻译：用于肝脏脂肪蓄积的抑制剂
公开(公告)号：JP2008208030A
公开(公告)日：2008-09-11
申请号：JP2005130513
申请日：2005-04-27
申请人： Toyo Shinyaku:Kk , 株式会社東洋新薬
发明人： TAKAGAKI KINYA
IPC分类号： A61K36/18 , A23L1/30 , A61P1/16 , A61P3/06 , A61P3/10 , A61P9/10 , A61P9/12
CPC分类号： A61K36/39 , A23L33/105
摘要： PROBLEM TO BE SOLVED: To find the new function of sweet potato stems and leaves to broaden the application range of the sweet potato stems and leaves, and to provide a new inhibitor for lipid accumulation in the liver. SOLUTION: They are intended to provide an inhibitor for lipid accumulation in the liver which comprises a processed product of sweet potato stems and leaves as the active ingredient, and to provide a food containing the inhibitor for lipid accumulation in the liver. Because of having excellent effects of inhibiting neutral fat accumulation and inhibiting total cholesterol accumulation in the liver, this inhibitor for lipid accumulation in the liver can prevent or ameliorate fatty liver and relieves the risks of cirrhosis, diabetes, hyperlipemia, hypertension, arteriosclerosis and so on. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：寻找甘薯茎叶的新功能，拓宽甘薯茎叶的应用范围，为肝脏脂质积累提供新的抑制剂。解决方案：它们旨在为肝脏中的脂质积聚提供抑制剂，其包含甘薯茎和叶的加工产物作为活性成分，并提供含有肝脏脂质积聚抑制剂的食物。由于具有抑制中性脂肪蓄积和抑制肝脏总胆固醇积累的优异效果，肝脏脂质积聚抑制剂可预防或改善脂肪肝，缓解肝硬化，糖尿病，高脂血症，高血压，动脉硬化等风险。。版权所有（C）2008，JPO＆INPIT

6. 发明申请

US20190192608A1 Chinese Herbal Oral Paste for Conditioning Yang Deficiency Constitution and Processing Method thereof 审中-公开
公开(公告)号：US20190192608A1
公开(公告)日：2019-06-27
申请号：US15967027
申请日：2018-04-30
申请人： Zhonghua CI
发明人： Zhonghua CI
IPC分类号： A61K36/8945 , A61K36/40 , A61K36/64 , A61K36/39 , A61K36/232 , A61K36/46 , A61K36/815 , A61K36/54 , A61K36/71 , A61K36/258 , A61K35/50 , A61K47/26 , A61K45/06 , A61K9/00
CPC分类号： A61K36/8945 , A61K9/0053 , A61K35/50 , A61K36/232 , A61K36/258 , A61K36/39 , A61K36/40 , A61K36/46 , A61K36/54 , A61K36/64 , A61K36/71 , A61K36/815 , A61K45/06 , A61K47/26 , A61K2236/13 , A61K2236/51
摘要： The present application discloses a Chinese herbal oral paste for conditioning yang deficiency constitution. The Chinese herbal oral paste includes the following raw material components :prepared rehmannia root, Chinese yam,dogberry,seed of Chinese dodder, angelica, eucommia ulmoides, lycium barbarum, cinnamon, fuling, cortex moutan, rhizoma alismatis,white atractylodes rhizome, radix polygonum multiflorum preparata, dried ginseng,processed aconite root,pprepared liquorice root,cumin,herba cistanche,fruit of Chinese magnoliavine,radix cyathulae, raspberry, nutmeg, fructus broussonetiae,epimedium,fructus psoraleae,rhizoma curculiginis,rhizoma acori graminei,morinda officinalis, human placenta,cynomorium songaricum,bitter cardamon, semen allii tuberosi,antler gelatin,xylitol,walnut kernel, and donkey-hide gelatin. The Chinese herbal oral paste of the present disclosure has a higher drug concentration and good taste, is particularly suitable for health preserving in winter and conditioning the yang deficiency constitution and is capable of achieving certain efficacy of strengthening physical health.

7. 发明申请

US20180028591A1 MALE AND FEMALE INFERTILITY HERBAL COMPOSITION 审中-公开
公开(公告)号：US20180028591A1
公开(公告)日：2018-02-01
申请号：US15224991
申请日：2016-08-01
申请人： Shaobin Ke
发明人： Shaobin Ke
IPC分类号： A61K36/9066 , A61K36/537 , A61K36/752 , A61K36/70 , A61K36/296 , A61K36/185 , A61K36/73 , A61K36/481 , A61K36/8945 , A61K36/65 , A61K36/28 , A61K36/605 , A61K36/39 , A61K36/344
CPC分类号： A61K36/9066 , A61K36/185 , A61K36/28 , A61K36/296 , A61K36/344 , A61K36/39 , A61K36/481 , A61K36/537 , A61K36/605 , A61K36/65 , A61K36/70 , A61K36/73 , A61K36/752 , A61K36/8945 , A61K2236/00 , A61K2300/00
摘要： An herbal composition that enhances and promotes fertility in both males and females by nourishing the kidney, regulating the liver and spleen, improving circulation of Qi and blood, and balancing the Yin and Yang through a unique composition consisting of natural herbs known in traditional Chinese medicine. The herbs create a synergy between each other that works to enhance fertility for both males and females. The composition consists of the following herbal ingredients mixed in varying weight percentages. goji berry, dodder seed, red sage root, green orange peel, processed fleece flower root, horny goat weed, codonopsis, raspberry, astragalus root, Chinese yam, white peony root, false daisy, mulberry, curcuma tuber, and cynomorium. The herbal ingredients are cleaned, purified and/or processed prior to formulation. The formulation process is at least partially dependent on the desired means of preparation and administering the composition.

8. 发明申请

US20170360733A1 AGING INHIBITOR 审中-公开
公开(公告)号：US20170360733A1
公开(公告)日：2017-12-21
申请号：US15534319
申请日：2015-12-01
申请人： NIHON SIZEN HAKKOH CO., LTD.
发明人： Naoki HIGASHI , Masahiro NAKANISHI
IPC分类号： A61K31/198 , A23K50/50 , A61K36/8998 , A61K36/8994 , A61K36/899 , A61K36/8967 , A61K36/8962 , A61K36/8945 , A61K36/888 , A61K36/88 , A61K36/87 , A61K36/81 , A61K36/78 , A61K36/752 , A61K36/736 , A61K36/73 , A61K36/605 , A61K36/60 , A61K36/535 , A61K36/52 , A61K36/49 , A61K36/48 , A61K36/44 , A61K36/42 , A61K36/31 , A61K36/282 , A61K36/28 , A61K36/23 , A61K36/185 , A61K36/16 , A61K36/07 , A61K36/03 , A61K31/4172 , A61K31/405 , A61K31/401 , A61K31/352 , A61K31/194 , A61K31/192 , A61K31/19 , A61K8/99 , A61K36/9066 , A23L2/52 , A23L33/105 , A23K10/12 , A61K36/9068
CPC分类号： A61K31/198 , A23K10/12 , A23K50/50 , A23L2/52 , A23L33/105 , A23V2002/00 , A61K8/99 , A61K31/19 , A61K31/192 , A61K31/194 , A61K31/196 , A61K31/197 , A61K31/352 , A61K31/353 , A61K31/401 , A61K31/405 , A61K31/4172 , A61K35/744 , A61K36/03 , A61K36/062 , A61K36/064 , A61K36/07 , A61K36/16 , A61K36/185 , A61K36/23 , A61K36/28 , A61K36/282 , A61K36/31 , A61K36/39 , A61K36/42 , A61K36/44 , A61K36/48 , A61K36/49 , A61K36/52 , A61K36/535 , A61K36/60 , A61K36/605 , A61K36/73 , A61K36/736 , A61K36/75 , A61K36/752 , A61K36/78 , A61K36/81 , A61K36/87 , A61K36/88 , A61K36/888 , A61K36/8945 , A61K36/8962 , A61K36/8967 , A61K36/899 , A61K36/8994 , A61K36/8998 , A61K36/9066 , A61K36/9068
摘要： An object of the present invention is to provide a senescence retarding agent that delays the onset of senescence symptoms and extends longevity, and is superior in safety. The senescence retarding agent of the present invention that achieves the object is characterized by containing a plant fermentation product as an active ingredient, the plant fermentation product being a mixture of the following: (a) a koji mold-fermented product of one or more kinds of beans and/or cereals selected from the group consisting of barley, black soybean, red rice, black rice, adzuki bean, adlay, Japanese millet, foxtail millet, and millet; (b) a yeast- and/or lactic acid bacterium-fermented product of one or more kinds of fruits selected from the group consisting of mikan (mandarin orange), grape, apple, yama-budo (crimson glory grape), peach, kaki (Japanese persimmon), papaya, nashi (Japanese pear), watermelon, ume (Japanese apricot), fig, karin (Chinese quince), pumpkin, kumquat, yuzu (Chinese lemon), loquat, apricot, jujube, chestnut, matatabi (silvervine), and sumomo (Japanese plum); (c) a yeast- and/or lactic acid bacterium-fermented product of one or more kinds of root crops and/or potatoes selected from the group consisting of murasaki-imo (purple sweet potato), kikuimo (Jerusalem artichoke), carrot, onion, satsuma-imo (sweet potato), satoimo (taro), jinenzyo (Japanese yam), daikon (Japanese radish), akakabu (red turnip), gobo (burdock root), renkon (lotus root), yacon, yuri-ne (lily bulb), kuwai (arrowhead), ginger, garlic, and turmeric; (d) a yeast- and/or lactic acid bacterium-fermented product of one or more kinds of flowers and/or leaf vegetables selected from the group consisting of cabbage, shiso (perilla), mulberry leaves, dokudami (Korean houttuynia), yomogi (wormwood), kumazasa (kuma bamboo grass), and dandelion; (e) a yeast- and/or lactic acid bacterium-fermented product of one or more kinds of seaweeds selected from the group consisting of kombu (sea tangle), wakame (Undaria pinnatifida), and mozuku (Nemacystus decipiens); (f) a yeast- and/or lactic acid bacterium-fermented product of one or more kinds of seeds selected from the group consisting of black sesame seeds, walnuts, and ginkgo nuts; and (g) a yeast- and/or lactic acid bacterium-fermented product of one or two kinds of mushrooms selected from the group consisting of maitake (Grifola frondosa) and shiitake (Lentinus edodes).

9. 发明授权

US09694043B2 Composition for preventing or treating hearing loss 有权
公开(公告)号：US09694043B2
公开(公告)日：2017-07-04
申请号：US14925265
申请日：2015-10-28
申请人： UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
发明人： Tong Ho Kang , Bin Na Hong
IPC分类号： A61K36/39 , A61K36/64 , A61K36/804 , A61K36/43 , A61K36/185 , A61K9/00 , A61K9/14 , A61K9/20 , A23L33/105 , A61K9/08
CPC分类号： A61K36/39 , A23L33/105 , A23V2002/00 , A61K9/0019 , A61K9/08 , A61K9/145 , A61K9/2018 , A61K9/2059 , A61K36/185 , A61K36/43 , A61K36/64 , A61K36/804 , A23V2200/30 , A23V2250/21 , A61K2300/00
摘要： A composition including Cuscuta japonica Choisy extract, or the extract of Rehmannia glutinosa Libschitz var. purpurea MAKINO and Cuscuta japonica Choisy is provided. The composition, which can be a pharmaceutical or food composition, is useful for preventing, ameliorating, or treating hearing loss. A method for ameliorating, preventing, or treating hearing loss, in particular, acoustic trauma, temporary or permanent hearing loss by effectively inhibiting the threshold shift induced by noise and the likes is disclosed.

10. 发明申请

US20170106040A1 COMPOSITION FOR PREVENTING AND TREATING MALE INFERTILITY, CONTAINING MIXED HERBAL EXTRACT AS ACTIVE INGREDIENT AND USE THEREOF 审中-公开
公开(公告)号：US20170106040A1
公开(公告)日：2017-04-20
申请号：US15310762
申请日：2015-04-08
申请人： Industrial Cooperation Foundation Chonbuk National University
发明人： Jong Kwan PARK
IPC分类号： A61K36/8962 , A61K36/39 , A23L33/00 , A23L33/10 , A23P10/40 , A23P10/28 , A23P10/30 , A23L2/52 , A61K36/746 , A23L33/105
CPC分类号： A61K36/8962 , A23L2/52 , A23L33/10 , A23L33/105 , A23L33/30 , A23P10/28 , A23P10/30 , A23P10/40 , A23V2002/00 , A61K36/39 , A61K36/43 , A61K36/746 , A61K2236/333 , A61K2300/00
摘要： A composition and health functional food for treating male infertility using a mixed herbal mixture. Through an in vitro sperm mobility promotion effect evaluation method experiment for investigating effects of an herbal extract of Morinda officinalis, Cuscuta seed, and/or Allium cepa of the present invention on changes in sperm count and mobility in human semen, it was verified that the composition increased sperm mobility. In addition, through an in vivo varicocele animal model evaluation method for investigating effects of the herbal extract on changes in sperm count and mobility in an in vivo varicocele animal model, it was verified that the composition samples of the present invention increased the sperm count in the semen obtained from spermiducts of a sample-administered group among varicocele-induced groups. Therefore, the herbal extract can be used in a pharmaceutical composition, health functional food, and health supplement food for treating male infertility.

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