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    • 8. 发明申请
    • Unsaturated Fatty Acids as Thrombin Inhibitors
    • 不饱和脂肪酸作为凝血酶抑制剂
    • US20090234007A1
    • 2009-09-17
    • US12084438
    • 2006-11-30
    • Hans-Rainer Hoffmann
    • Hans-Rainer Hoffmann
    • A61K31/201C07C57/03
    • A61K31/201A61K31/202A61K36/185A61K36/23A61K36/235A61K36/31A61K36/35A61K36/71A61K36/889A61K36/9064
    • A preparation having at least one unsaturated fatty acid and the use of at least one unsaturated fatty acid having a chain length of 18 or 20 carbon atoms and of plant drugs containing the unsaturated fatty acid as a free fatty acid or a fatty acid radical of a triglyceride. The fatty acid has a chain length of 18 carbon atoms which are provided with 1 to 3 double bonds and the fatty acid has a chain length of 20 carbon atoms which are provided with 1 to 4 double bonds. The double bond or one of the double bonds are located in position 9 or 11 of the carbon chain. The unsaturated fatty acid is supplied in the all-cis configuration. The at least one unsaturated fatty acid prevents and/or treats or is used for producing a preparation for preventing and/or treating thrombosis and thromboembolic diseases.
    • 具有至少一种不饱和脂肪酸和至少一种链长为18或20个碳原子的不饱和脂肪酸和含有不饱和脂肪酸的植物药物作为游离脂肪酸或脂肪酸基的制剂 甘油三酯。 脂肪酸具有18个碳原子的链长度,其具有1至3个双键,脂肪酸具有20个碳原子的链长度,其具有1至4个双键。 双键或双键中的一个位于碳链的9或11位。 不饱和脂肪酸以全顺式构型提供。 至少一种不饱和脂肪酸防止和/或治疗或用于制备预防和/或治疗血栓形成和血栓栓塞性疾病的制剂。