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1. 发明授权

US06524232B1 Method for radioactive stent delivery 有权
标题翻译：放射性支架输送方法
公开(公告)号：US06524232B1
公开(公告)日：2003-02-25
申请号：US09746267
申请日：2000-12-22
申请人： Fuh-Wei Tang , Ty Tiefeng Hu , Jean-Francois Corbett
发明人： Fuh-Wei Tang , Ty Tiefeng Hu , Jean-Francois Corbett
IPC分类号： A61M3604
CPC分类号： A61K51/1282 , A61N5/1002
摘要： A method for delivering multiple doses of radiation to a target area of a vessel. The method includes delivering multiple radioisotopes to a target area of a vessel and allowing the radioisotopes to dwell in the target area for a period of time to deliver a predetermined and uniform radiation dose.
摘要翻译：一种用于将多个剂量的辐射递送到血管的目标区域的方法。该方法包括将多个放射性同位素输送到容器的目标区域，并允许放射性同位素在目标区域内停留一段时间以递送预定和均匀的辐射剂量。

2. 发明授权

US06569076B1 Radioactive source train 有权
标题翻译：放射源火车
公开(公告)号：US06569076B1
公开(公告)日：2003-05-27
申请号：US09616260
申请日：2000-07-14
申请人： Charles E. Larsen , Robert C. Farnan
发明人： Charles E. Larsen , Robert C. Farnan
IPC分类号： A61M3604
CPC分类号： A61N5/1002 , A61N2005/1023 , A61N2005/1025
摘要： A treating element source train that comprises a plurality of treating elements, with each treating element comprising a hollow outer housing closed on each end and a radiation emitting substance encapsulated therein. The treating elements are aligned end-to-end, and a wire is wound around the exterior of the treating elements to maintain the treating elements in their end-to-end relationship. The wire may be helically coiled about the treating elements, or braided around them. Also, the wire may be secured to the proximal and distal treating elements, or to each individual treating element. Preferably, the wire is made of a radiopaque material such as gold, platinum, platinum iridium, tungsten and tantalum. In an alternate embodiment, the source train may be provided with an end cap at either end, with the wire jacket being secured to each endcap.
摘要翻译：一种处理元件源列，其包括多个处理元件，每个处理元件包括在每一端封闭的中空外壳体和封装在其中的辐射发射物质。处理元件端对齐地对准，并且线缠绕在处理元件的外部，以将处理元件保持在它们的端对端关系中。线可以围绕治疗元件螺旋卷绕，或围绕它们编织。此外，线可以固定到近端和远端处理元件或每个单独的处理元件。优选地，导线由不透射线的材料制成，例如金，铂，铂铱，钨和钽。在替代实施例中，源列可以在任一端设置有端盖，其中电线护套固定到每个端盖。

3. 发明授权

US06605031B1 Stepped centering balloon for optimal radiation delivery 有权
标题翻译：步进的定心气球，以获得最佳的辐射输送
公开(公告)号：US06605031B1
公开(公告)日：2003-08-12
申请号：US09505340
申请日：2000-02-16
申请人： Firas Mourtada , Eric D. Peterson
发明人： Firas Mourtada , Eric D. Peterson
IPC分类号： A61M3604
CPC分类号： A61M25/1002 , A61M2025/1047 , A61N5/1002 , A61N2005/1003
摘要： A stepped centering catheter for delivery of intravascular radiation therapy including a central segment of a first effective diameter and smaller, offset segments of second effective diameters to each side of the central segment. The first effective diameter of the central segment substantially centers a portion of a radiation source within the lumen of a vessel along a therapeutic treatment length. The second effective diameters of the offset segments constrain portions of the radioactive source that extend beyond the therapeutic treatment length within a region having a minimum offset distance from the vessel wall. The first effective diameter of the central segment is gradually tapered to the second effective diameter of the offset segments across first steps. The second effective diameters of the offset segments are gradually tapered to the diameter of the catheter shaft across second steps. The smaller diameter offset segments and tapered change in diameters mitigates further injury to vessel walls located outside the therapeutic treatment length.
摘要翻译：一种用于递送血管内放射治疗的阶梯式定心导管，包括第一有效直径的中心段和较小的第二有效直径的偏移段到中心段的每一侧。中心段的第一有效直径基本上使辐射源的一部分沿着治疗处理长度居中在容器的腔内。偏移段的第二有效直径将放射源的部分限制在距离血管壁最小偏移距离的区域内延伸超过治疗处理长度。中心段的第一有效直径在第一步骤中逐渐变细到偏移段的第二有效直径。偏移段的第二有效直径在第二步骤中逐渐变细到导管轴的直径。较小的直径偏移段和直径的锥形变化减轻了位于治疗治疗长度之外的血管壁的进一步损伤。

4. 发明授权

US06387035B1 Catheter with swivel tip 有权
标题翻译：导管带旋转头
公开(公告)号：US06387035B1
公开(公告)日：2002-05-14
申请号：US09436666
申请日：1999-11-10
申请人： Eugene J. Jung, Jr. , James D. Savage
发明人： Eugene J. Jung, Jr. , James D. Savage
IPC分类号： A61M3604
CPC分类号： A61N5/1002 , A61N2005/1005
摘要： A device and method for precisely delivering dosage of radiation from a radiation source to a treatment site of a vessel is provided herein. In one embodiment, the device includes a catheter which inserts into a vessel lumen of the body. The catheter includes an adjuster section for altering a portion of the radiation emitting radially from the radiation source so that the radiation source delivers an asymmetrical radiation profile to the vessel. The device can also include a catheter supporter which inhibits rotational deformation in the catheter between a catheter distal end and a catheter proximal end. This allows the delivery section to be precisely rotated to properly position the adjuster section within the vessel lumen.
摘要翻译：本文提供了一种用于将辐射源的辐射剂量准确地输送到容器的处理部位的装置和方法。在一个实施例中，该装置包括插入身体的血管腔的导管。导管包括调节器部分，用于改变从辐射源径向辐射的辐射的一部分，使得辐射源将不对称辐射轮廓传送到血管。该装置还可以包括导管支撑件，其阻止导管在导管远端和导管近端之间的旋转变形。这允许输送部分被精确地旋转以将调节器部分适当地定位在血管内腔内。

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