专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

EP3174848B1 VERFAHREN ZUR HERSTELLUNG VON POLYGUANIDINEN 有权
公开(公告)号：EP3174848B1
公开(公告)日：2018-08-01
申请号：EP15771843.8
申请日：2015-07-30
申请人： Sealife Pharma GmbH
发明人： PRETSCH, Alexander , NAGL, Michael , WIESNER, Christoph , HOLLAUS, Ralph , GENOV, Miroslav
IPC分类号： A61K45/06 , C07C277/08 , A61K31/155
CPC分类号： A61K31/785 , A01N47/44 , A61K31/155 , A61K45/06 , C07C277/08 , C07C279/00 , C07D213/42 , C08G73/00 , C08G73/0627 , A61K2300/00 , C07C279/04

2. 发明授权

EP2804888B1 PROTON-CONDUCTING MEMBRANE, METHOD FOR THEIR PRODUCTION AND THEIR USE IN ELECTROCHEMICAL CELLS 有权
标题翻译：质子传导膜，其制造方法相同，它们在电化学电池
公开(公告)号：EP2804888B1
公开(公告)日：2017-03-15
申请号：EP13738112.5
申请日：2013-01-16
申请人： BASF SE , BASF Schweiz AG
发明人： BENICEWICZ, Brian, , BRÄUNINGER, Sigmar , CALUNDANN, Gordon , MOLLEO, Max , QIAN, Guoqing
IPC分类号： C08G73/18 , H01M4/86 , H01M8/10
CPC分类号： H01M8/1041 , C08G73/0611 , C08G73/0616 , C08G73/0627 , C08G73/0633 , C08G73/0688 , C08G73/18 , H01M4/8892 , H01M8/102 , H01M8/1027 , H01M8/103 , H01M8/1067 , H01M2008/1095 , Y02P70/56

3. 发明授权

EP2414089B1 MEMBRANE POLYMERE DYNAMIQUE AUTOSUPPORTEE, PROCEDE DE PREPARATION ET UTILISATIONS 有权
标题翻译：自支持动态高分子膜，方法和用途
公开(公告)号：EP2414089B1
公开(公告)日：2014-12-31
申请号：EP10716379.2
申请日：2010-03-11
申请人： Centre National de la Recherche Scientifique
发明人： NASR, Gihane , BARBOIU, Mihail-Dumitru , CHARMETTE, Christophe , SANCHEZ MARCANO, José, Gregorio
IPC分类号： B01D71/60 , B01D71/80 , B01D67/00 , C08G73/04 , H01M8/10
CPC分类号： B01D67/0006 , B01D71/52 , B01D71/60 , B01D71/62 , B01D71/80 , B01D2325/20 , C08G65/331 , C08G65/33306 , C08G73/00 , C08G73/0627 , C08G2650/50 , C08J5/2256 , C08J2379/02 , C08L79/00 , C08L79/04 , H01G9/2009 , H01M8/0289 , H01M8/103 , Y02E60/521

4. 发明公开

EP2586447A1 HETEROCHAIN ALIPHATIC POLY-N-OXIDE COPOLYMERS AND VACCINATING AGENTS AND DRUGS BASED THEREON 审中-公开
标题翻译：阿拉伯联合酋长国高分子聚氧乙烯共聚物SOWIE DARAUF BASIERENDE IMPFSTOFFE UND ARZNEIMITTEL
公开(公告)号：EP2586447A1
公开(公告)日：2013-05-01
申请号：EP11798436.9
申请日：2011-06-20
申请人： Obchtchestvo S Ogranitchennoi Otvetstvennostyou '' NPO Petrovaks Farm"
发明人： NEKRASOV, Arkady Vasilievich , PUCHKOVA, Natalya Grigoryevna
IPC分类号： A61K31/787 , C08G73/02 , C08F8/06 , A61K39/44 , A61K47/48 , A61P39/04 , A61P39/06 , A61P37/02
CPC分类号： A61K31/787 , A61K31/424 , A61K31/546 , A61K45/06 , C08G73/0627 , C08G73/0633 , C08L79/04 , A61K2300/00
摘要： The invention relates to the field of synthesizing high molecular weight chemical compounds that exhibit biological activity for the production of highly effective pharmacological preparations and vaccines and, more specifically, to heterochain aliphatic poly-N-oxide copolymers of general formula. (1), where R = N, CH; x = 2 or 4; y = 0 or 2; n = 10 - 1000; q = (0.1 - 0.9)n; z = (0.1 - 0.9)n, which exhibit pharmacological activity, including an antioxidant effect and a therapeutic effect as a detoxicant and immunomodulating agent. Also claimed are: a vaccinating agent comprising an antigen and a formula (1) copolymer as an immunomodulating agent; and a vaccine against hepatitis A and hepatitis B, which contains a vaccine preparation comprising HVA Ag and HBsAg simultaneously or vaccine preparations against hepatitis A and against hepatitis B and a formula (1) heterochain aliphatic poly-N-oxide copolymer, A drug is described which comprises a medicinal substance and a formula (1) copolymer as a carrier. The invention represents a new class of compounds that exhibit a wide range of pharmacological activity and a vaccination effect as well as increased safety in use, and is directed towards increasing manufacturability, cost efficiency and environmental safety in the production of drugs.
摘要翻译：本发明涉及合成高分子化合物的领域，该化合物具有用于生产高效药理学制剂和疫苗的生物活性，更具体地说，涉及通式为的杂链脂族聚-N-氧化物共聚物。（1），其中R = N，CH; x = 2或4; y = 0或2; n = 10-1000; q =（0.1-0.9）n; z =（0.1〜0.9）n，其具有药理活性，包括抗氧化作用和作为除毒剂和免疫调节剂的治疗作用。还要求的是：包含抗原和式（1）共聚物作为免疫调节剂的疫苗接种剂; 和一种针对甲型和乙型肝炎的疫苗，其中含有包含HVA Ag和HBsAg的疫苗制剂，或者针对乙型肝炎和乙型肝炎的疫苗制剂和式（1）杂链脂族聚-N-氧化物共聚物，描述了一种药物其包含药物和式（1）共聚物作为载体。本发明代表了一类新的化合物，其具有广泛的药理活性和疫苗接种效果以及使用中的安全性，并且旨在提高药物生产中的可制造性，成本效率和环境安全性。

5. 发明授权

EP1754738B1 PROCESS FOR PRODUCING POLYPYRIDINIUM 有权
标题翻译：用于生产POLYPYRIDINIUM
公开(公告)号：EP1754738B1
公开(公告)日：2012-05-30
申请号：EP05721280.5
申请日：2005-03-23
申请人： Japan Science and Technology Agency
发明人： IYODA, Tomokazu , KAMATA, Kaori , SUZUKI, Yukimitsu
IPC分类号： C08G73/06
CPC分类号： C08G73/0627
摘要： [PROBLEMS] To provide a process for producing polypyridinium having a narrow molecular weight distribution and a desired molecular weight. [MEANS FOR SOLVING PROBLEMS] A pyridine derivative monomer (2) is polymerized with a polymerization initiator (1) specially designed, such as a 4-halopyridinium, in the presence of a dissolution accelerator (e.g., tetrabutylammonium tetrafluoroborate) for dissolving the polymer to be yielded in a solvent to thereby synthesize a polypyridinium (3) having a narrow molecular weight distribution and a desired molecular weight, as shown in the following scheme (Chemical formula 4). [Chemical formula 4] (1) + (2) → (3) (In the scheme, Y is an anion dissolving in the organic solvent; X and Z each is halogeno; R is a hydrocarbon group, etc.; and o is 1 to about 300.)

6. 发明公开

EP2414089A1 MEMBRANE POLYMERE DYNAMIQUE AUTOSUPPORTEE, PROCEDE DE PREPARATION ET UTILISATIONS 有权
标题翻译：自支持动态高分子膜，方法和用途
公开(公告)号：EP2414089A1
公开(公告)日：2012-02-08
申请号：EP10716379.2
申请日：2010-03-11
申请人： Centre National de la Recherche Scientifique
发明人： NASR, Gihane , BARBOIU, Mihail-Dumitru , CHARMETTE, Christophe , SANCHEZ MARCANO, José, Gregorio
IPC分类号： B01D71/60 , B01D71/80 , B01D67/00 , C08G73/04 , H01M8/10
CPC分类号： B01D67/0006 , B01D71/52 , B01D71/60 , B01D71/62 , B01D71/80 , B01D2325/20 , C08G65/331 , C08G65/33306 , C08G73/00 , C08G73/0627 , C08G2650/50 , C08J5/2256 , C08J2379/02 , C08L79/00 , C08L79/04 , H01G9/2009 , H01M8/0289 , H01M8/103 , Y02E60/521
摘要： The present invention relates to self-supporting dynamic polymer membranes (called "dynamer" membranes) of the polyimine type, to their method of preparation and to their use in separation processes, especially for separating gaseous species.

7. 发明公开

EP2387807A1 MONOMERPERLEN ZUR HERSTELLUNG EINER PROTONENLEITENDEN MEMBRAN 有权
标题翻译：单体小珠的制备质子导电膜
公开(公告)号：EP2387807A1
公开(公告)日：2011-11-23
申请号：EP10701200.7
申请日：2010-01-14
申请人： BASF SE
发明人： LEITNER, Klaus , NAWALADE, Sameer
IPC分类号： H01M8/10 , C08G73/18
CPC分类号： C08G73/18 , C08G73/0627 , C08G73/0633 , H01M8/0289 , H01M8/103 , H01M8/1048 , H01M8/1072 , H01M8/109 , Y02E60/521 , Y02P70/56
摘要： The invention relates to monomer beads, attainable according to a method, wherein i. one or more aromatic tetra-amino compounds are mixed in an extruder with one or more aromatic carboxylic acids comprising at least two acid groups per carboxylic acid monomer and melted at 190°C-270°C; ii. the melt drips at 190°C-270°C via a nozzle located at the extruder exit; iii. the fluid droplets are captured, cooled and solidified. The monomer beads are in particular suited for producing a proton-conducting polymer membrane based on polyazoles.

8. 发明公开

EP2141149A4 PROCESS FOR PRODUCING SUBSTITUTED METHYLAMINE COMPOUND AND TRIAZINE DERIVATIVE 有权
标题翻译：制造方法取代的甲基胺化合物和三嗪衍生物
公开(公告)号：EP2141149A4
公开(公告)日：2011-01-19
申请号：EP07742277
申请日：2007-04-24
申请人： NIPPON SODA CO
发明人： SHIBATA YASUSHI , IMAGAWA TSUTOMU
IPC分类号： C07D213/61 , C07B43/04 , C07D401/06
CPC分类号： C07D213/61 , C07B43/04 , C07C209/06 , C07C211/03 , C07C211/48 , C07C211/62 , C07D251/04 , C07D257/08 , C07D277/20 , C07D401/06 , C07D401/14 , C08G73/0627 , C08G73/0644
摘要： The present invention provides a process that enables a substituted methylamine compound which is useful as an intermediate for the production of agricultural chemicals and medicines, to be produced easily, with good yield, and at low cost, and also provides a production intermediate thereof. The process comprises a step of reacting a hexamethylenetetraammonium salt compound represented by a formula (I) with a base to obtain an N-methylidene-substituted methylamine oligomer represented by a formula (II) or a mixture of two or more of the oligomers, and a step of hydrolyzing the N-methylidene-substituted methylamine oligomer represented by formula (II) or the mixture of two or more of the oligomers in the presence of an acid. (wherein A represents an organic group that is either a hydrocarbon group or a heterocyclic group, or said organic group that has a substituent, R represents a hydrogen atom, an organic group that is either a hydrocarbon group or a heterocyclic group, or said organic group that has a substituent, L represents a halogen atom and the like, and n represents an integer of 2 to 20)

9. 发明公开

EP1759713A2 Lock and key micelles 失效
标题翻译： Schlüssel-宫，Mizelle
公开(公告)号：EP1759713A2
公开(公告)日：2007-03-07
申请号：EP06026544.4
申请日：1997-08-26
申请人： UNIVERSITY OF SOUTH FLORIDA
发明人： Newkome, George R. , Moorefield, Charles N.
IPC分类号： A61K47/48 , C07C233/47 , C07D213/68 , C07D213/75 , C07D239/62 , C07D239/64 , C08G73/02
CPC分类号： C07D213/75 , B82Y5/00 , C07C233/47 , C07D213/68 , C07D239/62 , C07D239/64 , C08G73/028 , C08G73/0627 , Y10S424/16 , Y10S525/936 , Y10S530/816 , Y10T428/2985 , Y10T428/2987
摘要： A lock unimolecular micelle includes at least one engineered acceptor specifically binding a ligand (or specifically a "key" unimolecular micelle) thereto. A key unimolecular micelle comprises a core molecule and a plurality of branches extending therefrom, at least one of the branches including a shank portion extending therefrom having a terminal moiety at an end thereof for binding to a complimentary acceptor of a lock unimolecular micelle. Together, the lock and key micelles form a unit, either irreversibly or reversibly bound wherein the lock micelle is a soluble receptor engineered to specifically bind to the specifically engineered key micelle.
摘要翻译：锁单分子胶束包括至少一个工程化受体，其特异性结合配体（或特别是“键”单分子胶束）。关键的单分子胶束包括芯分子和从其延伸的多个分支，至少一个分支包括从其延伸的柄部分，其端部具有末端部分，用于结合锁定单分子胶束的互补受体。锁和键胶束一起形成不可逆或可逆地结合的单元，其中锁定胶束是被工程化以特异性结合特异性工程化键键合的可溶性受体。

10. 发明授权

EP1007011B1 LOCK AND KEY MICELLES 失效
标题翻译： KEY LOCK胶束
公开(公告)号：EP1007011B1
公开(公告)日：2006-12-27
申请号：EP97944295.1
申请日：1997-08-26
申请人： UNIVERSITY OF SOUTH FLORIDA
发明人： NEWKOME, George, R. , MOOREFIELD, Charles, N.
IPC分类号： A61K9/50 , A61K9/107 , B01J13/22 , C07C235/74 , A61K47/48
CPC分类号： C07D213/75 , B82Y5/00 , C07C233/47 , C07D213/68 , C07D239/62 , C07D239/64 , C08G73/028 , C08G73/0627 , Y10S424/16 , Y10S525/936 , Y10S530/816 , Y10T428/2985 , Y10T428/2987
摘要： A lock unimolecular micelle includes at least one engineered acceptor specifically binding a ligand (or specifically a 'key' unimolecular micelle) thereto. A key unimolecular micelle comprises a core molecule and a plurality of branches extending therefrom, at least one of the branches including a shank portion extending therefrom having a terminal moiety at an end thereof for binding to a complimentary acceptor of a lock unimolecular micelle. Together, the lock and key micelles form a unit, either irreversibly or reversibly bound wherein the lock micelle is a soluble receptor engineered to specifically bind to the specifically engineered key micelle.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式