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    • 5. 发明专利
    • Film preparation for oral mucosa
    • 口腔粘液膜的制备
    • JP2009280611A
    • 2009-12-03
    • JP2009195168
    • 2009-08-26
    • Kyukyu Yakuhin Kogyo Kk救急薬品工業株式会社
    • SURIDEJI KAZUYOSHIKAKICHI MEGUMI
    • A61K9/70A61K31/4468A61K47/02A61K47/10A61K47/12A61K47/32A61K47/36A61K47/38A61P25/04
    • PROBLEM TO BE SOLVED: To provide a film preparation for the oral mucosa including a pH regulator for improving the absorption through the oral mucosa and eliminating the instability of a drug by effects of the pH regulator in the film preparation of the type through the oral mucosa by applying to the oral mucosa or dissolving in the oral cavity and absorbing the drug through the oral mucosa.
      SOLUTION: The film preparation for the oral mucosa is provided with a soluble drug layer containing the drug and disintegrating or soluble non-drug layers without containing the drug. The pH regulator for improving the absorption of the drug through the oral mucosa is contained in the non-drug layers without including the pH regulator in the drug layer. In particular, the drug is a compound of fentanyls. The pH regulator is such as sodium hydroxide, trisodium phosphate, anhydrous dibasic sodium phosphate, citric acid, etc.
      COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:提供一种用于口腔粘膜的膜制剂,其包括用于改善通过口腔粘膜的吸收的pH调节剂,并通过pH调节剂在类型通过的膜制备中的作用消除药物的不稳定性 口腔粘膜通过施用于口腔粘膜或溶解在口腔中并通过口腔粘膜吸收药物。 解决方案:用于口腔粘膜的薄膜制剂提供含有不含药物的药物和崩解或可溶性非药物层的可溶性药物层。 用于改善药物通过口腔粘膜吸收的pH调节剂包含在非药物层中,而不包括药物层中的pH调节剂。 特别地,该药物是芬太尼的化合物。 pH调节剂如氢氧化钠,磷酸三钠,无水磷酸氢二钠,柠檬酸等。版权所有(C)2010,JPO&INPIT
    • 7. 发明专利
    • Sheet-form compound drying device with microwaves
    • 具有微波的片状复合干燥装置
    • JP2005265271A
    • 2005-09-29
    • JP2004077618
    • 2004-03-18
    • Idx CorpKyukyu Yakuhin Kogyo Kk救急薬品工業株式会社株式会社Idx
    • OKAMOTO TADASHIYASUDA MASAHIROSON HIYOTAKAYANAGI HITOSHIFURUSAWA KAZUYOSHI
    • H05B6/68F26B3/347F26B13/04F26B13/10F26B23/08
    • Y02B40/143
    • PROBLEM TO BE SOLVED: To provide a sheet-form compound drying device with microwaves capable of removing alcohols quickly by heating the sheet uniformly with a high efficiency, the sheet having an exfoliate sheet coated with compound containing water-soluble high-polymer substance or ethanol-soluble high-polymer substance which is dissolved or suspended in a solvent consisting of ethanol or water.
      SOLUTION: The sheet-form compound drying device has its basic portion consisting of a cavity resonator 1 exciting an electric field having a very high intensity and approximately uniform in the width direction of sheet-form compound W. The sheet-form compound W to be dried is heated in receiving the action of the electric field generated in the cavity while it passes through the cavity resonator 1 via openings 4a and 5a, and high efficiency drying is conducted owing to quick evaporation of a dissolving agent used as the solvent. The cavity resonator 1 generates an intense electric field uniform in the sheet width direction, and the electric field heats selectively the solvent in the sheet-form compound, which allows uniform drying with good efficiency and accomplishing suppression of the space and saving the energy.
      COPYRIGHT: (C)2005,JPO&NCIPI
    • 要解决的问题:为了提供具有能够通过以高效率均匀加热片材来快速除去醇的微波炉的片状复合干燥装置,该片材具有涂覆有含有水溶性高分子聚合物的化合物的剥离片 溶解或悬浮在由乙醇或水构成的溶剂中的物质或乙醇可溶性高分子物质。 解决方案:片状复合干燥装置的基本部分包括空腔谐振器1,其激发在片状化合物W的宽度方向上具有非常高的强度和近似均匀的电场。片状化合物 待干燥的W被加热以在其经由开口4a和5a通过空腔谐振器1时在空腔中产生的电场的作用被加热,并且由于用作溶剂的溶解剂的快速蒸发而进行高效干燥 。 腔谐振器1在片宽方向上产​​生均匀的强电场,并且电场选择性地加热片状化合物中的溶剂,其能够以良好的效率进行均匀干燥并且实现空间的抑制并节省能量。 版权所有(C)2005,JPO&NCIPI