专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

91. 发明授权

US07943909B2 Fluorescence detecting apparatus and fluorescence observation system 有权
标题翻译：荧光检测装置和荧光观察系统
公开(公告)号：US07943909B2
公开(公告)日：2011-05-17
申请号：US12482608
申请日：2009-06-11
申请人： Shigeyuki Mano
发明人： Shigeyuki Mano
IPC分类号： G01J1/58 , G01J3/50 , G02B21/00
CPC分类号： G02B21/0076 , G01N21/6458 , G01N2021/6419 , G01N2021/6421 , G02B21/0064
摘要： A fluorescence detecting apparatus includes a light detecting device disposed in a light path of fluorescence generated in an illuminated area of a specimen and a barrier filter disposed in the light path toward the light detecting device to exhibit transparency for each of a plurality of fluorescences having separated wavelength bands.
摘要翻译：荧光检测装置包括：光检测装置，其设置在在样本的被照射区域中产生的荧光的光路中;以及屏障滤光器，设置在光路中，朝向光检测装置，以对于具有分离的多个荧光体的每一个显示透明度波段。

92. 发明申请

US20110112388A1 INTEGRATED MINIATURIZED FIBER OPTIC PROBE 有权
标题翻译：集成微型光纤探头
公开(公告)号：US20110112388A1
公开(公告)日：2011-05-12
申请号：US12613715
申请日：2009-11-06
申请人： Thomas F. Kuech , Nirmala Ramanujam , Leon McCaughan
发明人： Thomas F. Kuech , Nirmala Ramanujam , Leon McCaughan
IPC分类号： A61B5/1459 , H01J40/00 , G01J5/10 , G01J3/44 , A61B6/00 , G01J1/58
CPC分类号： A61B5/1459 , A61B5/14546 , A61B5/14556 , G01J1/02 , G01J1/0233 , G01J1/04 , G01J1/0403 , G01J1/0425 , G01J1/4228 , G01J1/58 , G01J3/02 , G01J3/0202 , G01J3/0218 , G01J3/0272 , G01J3/2803 , G01J3/44 , G01J5/08 , G01J5/0818 , G01J5/0821 , G01J5/10
摘要： A fiber optic probe having one or more photodetectors bound thereto is provided. By directly integrating thin, flexible photodetectors with an optical fiber, the probes provide a compact structure that increases throughput and decreases cost, making it practical for a clinical use. In some embodiments, the fiber optic probes are small enough for insertion into the shaft of a needle, such as a biopsy needle.
摘要翻译：提供了具有一个或多个与其结合的光电探测器的光纤探针。通过直接将薄型，柔性光电探测器与光纤集成在一起，探头提供了一种结构紧凑的结构，可以增加产量并降低成本，从而使临床使用成为可能。在一些实施例中，光纤探针足够小以插入到针的轴中，例如活检针。

93. 发明申请

US20110095204A1 Method and apparatus for measuring the phase shift iduced in a light signal by a sample 有权
标题翻译：用于测量由样品在光信号中产生的相移的方法和装置
公开(公告)号：US20110095204A1
公开(公告)日：2011-04-28
申请号：US12929073
申请日：2010-12-29
申请人： Søren Aasmul
发明人： Søren Aasmul
IPC分类号： G01J1/58
CPC分类号： G01N21/6408 , G01J3/4406 , G01N21/274 , G01N21/6428 , G01N21/645 , G01N27/3271 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441
摘要： A first light source emits a light signal along a measurement optical path that includes a sample and a second light source emits a light signal along a dummy measurement optical path. A measurement circuit receives the light signals and provides outputs separated in time which are indicative of the phase of the respective light signals. A phase shift is induced in light in the measurement optical path by the sample. A reference circuit receives a signal indicative of the phase of the light signals emitted by the first and second light sources. Circuitry compares the phases of light output from the two circuits to provide output indicative of a first measured phase difference during operation of the first light source. Correction is applied to this measurement by taking a similar phase difference measurement during operation of the second light source and comparing the two phase differences.
摘要翻译：第一光源沿着包括样本的测量光路发射光信号，并且第二光源沿着虚拟测量光路发射光信号。测量电路接收光信号并提供时间上分离的指示相应光信号的相位的输出。通过样品在测量光路中的光中引起相移。参考电路接收指示由第一和第二光源发射的光信号的相位的信号。电路比较来自两个电路的光输出的相位，以在第一光源的操作期间提供指示第一测量相位差的输出。通过在第二光源的操作期间进行相似的相位差测量并比较两个相位差，对该测量进行校正。

94. 发明申请

US20110084199A1 OPTICAL SENSOR USING NANO-SPACER AND DETECTION METHOD USING THE SAME 审中-公开
标题翻译：使用纳米间隔物的光学传感器和使用其的检测方法
公开(公告)号：US20110084199A1
公开(公告)日：2011-04-14
申请号：US12900030
申请日：2010-10-07
申请人： Hyeon Bong PYO
发明人： Hyeon Bong PYO
IPC分类号： H01J40/14 , G01N21/55 , G01J3/44 , G01J1/58
CPC分类号： G01J5/58 , G01J1/58 , G01J3/44 , G01N21/554 , G01N21/658 , G01N21/77 , G01N2021/6441
摘要： An optical sensor includes: a nano-spacer a length of which is reversibly varied depending on an external stimuli; a first material body coupled to one side of the nano-spacer; a second material body coupled to the other side of the nano-spacer; and a detection unit detecting light emitted by an interaction between the first material body and the second material body.
摘要翻译：光学传感器包括：纳米间隔物，其长度根据外部刺激而可逆地变化; 耦合到所述纳米间隔物的一侧的第一材料体; 耦合到所述纳米间隔物的另一侧的第二材料体; 以及检测单元，其检测由所述第一材料体和所述第二材料体之间的相互作用发射的光。

95. 发明授权

US07919761B2 Fluorescence observation apparatus 有权
标题翻译：荧光观察装置
公开(公告)号：US07919761B2
公开(公告)日：2011-04-05
申请号：US12883932
申请日：2010-09-16
申请人： Yasushige Ishihara
发明人： Yasushige Ishihara
IPC分类号： G01J1/58
CPC分类号： A61B5/0071 , A61B1/00009 , A61B1/041 , A61B1/043 , A61B1/045 , A61B1/05 , A61B1/0638 , A61B1/0646 , A61B5/0084 , G01N21/55 , G01N21/6456 , G01N2021/6484
摘要： Clearly observing the state of an examination site is made by sufficiently suppressing the influence of residues. Fluorescence observation apparatus includes: a light source emits excitation light for irradiating the vicinity of an examination site; a fluorescence information acquisition unit acquires information about fluorescence emitted from the vicinity of the examination site through the irradiation with the excitation light from the light source; a residue fluorescence information acquisition unit acquires information about fluorescence emitted from residues selectively dyed with a fluorescent dye, through the irradiation with the excitation light from the light source; and a fluorescence information correction unit generates fluorescence information about the examination site in which the fluorescence from the residues is suppressed, based on the fluorescence information from the vicinity of the examination site, acquired by the fluorescence information acquisition unit, and the fluorescence information from the residues, acquired by the residue fluorescence information acquisition unit.
摘要翻译：通过充分抑制残留物的影响，清楚地观察检查点的状态。荧光观察装置包括：光源发射用于照射检查部位附近的激发光; 荧光信息获取单元通过来自光源的激发光的照射来获取关于从检查部位附近发出的荧光的信息; 残留荧光信息获取单元通过用来自光源的激发光的照射来获取关于用荧光染料选择性染色的残留物发出的荧光的信息; 并且荧光信息校正单元基于由荧光信息获取单元获取的来自检查部位附近的荧光信息和从荧光信息获取单元获取的荧光信息，生成关于来自残基的荧光被抑制的检查部位的荧光信息残留物，由残留荧光信息获取单元获取。

96. 发明申请

US20110057118A1 Method of Indirect Emission by Nano-materials 有权
标题翻译：纳米材料的间接排放方法
公开(公告)号：US20110057118A1
公开(公告)日：2011-03-10
申请号：US12869788
申请日：2010-08-27
申请人： Yan Zheng , Jingyu Bian , Shufan Geng , Ruifu Yang , Lei Zhou , Huijie Huang , Youbao Zhang , Lihua Huang
发明人： Yan Zheng , Jingyu Bian , Shufan Geng , Ruifu Yang , Lei Zhou , Huijie Huang , Youbao Zhang , Lihua Huang
IPC分类号： G01J1/58
CPC分类号： G01N21/6428 , B82Y15/00 , B82Y20/00 , G01N2021/6441 , G01N2201/06193
摘要： A method of indirect emission by nano-materials includes providing an infrared up-conversion phosphor 1 (weight ratio) and a long-wave ultraviolet phosphor 0.01-10 (weight ratio); treating both surfaces of the infrared up-conversion phosphor and the long-wave ultraviolet phosphor; mixing the infrared up-conversion phosphor and the long-wave ultraviolet phosphor; exciting the infrared up-conversion phosphor by a near-infrared laser with a wavelength of 980 mn to emit blue light as a secondary excitation lightsource; exciting the long-wave ultraviolet phosphor by the blue light to emit a visible light. Biological reactions can be conveniently detected by detecting the visible light.
摘要翻译：纳米材料间接发射的方法包括提供红外线上转换荧光体1（重量比）和长波紫外线荧光粉0.01-10（重量比）; 处理红外线上变换荧光体和长波紫外线荧光体的两面; 混合红外线上转换荧光体和长波紫外线荧光体; 通过波长980nm的近红外激光激发红外上转换荧光体，发射蓝光作为次级激发光源; 通过蓝光激发长波紫外线荧光体发出可见光。通过检测可见光可以方便地检测生物反应。

97. 发明申请

US20110057117A1 OPTICAL SYSTEM FOR MULTIPLE REACTIONS 有权
标题翻译：多种反应的光学系统
公开(公告)号：US20110057117A1
公开(公告)日：2011-03-10
申请号：US12841725
申请日：2010-07-22
申请人： Adrian Fawcett , David Tracy , Kevin Daley Simmons
发明人： Adrian Fawcett , David Tracy , Kevin Daley Simmons
IPC分类号： G01J1/58 , F21S4/00 , F21V5/00 , F21V9/16
CPC分类号： G01N21/6486 , B01L7/52 , B01L2300/046 , B01L2300/0829 , B01L2300/1805 , G01N21/0332 , G01N21/6452 , G01N2021/0367 , G01N2021/6421 , G01N2021/6471 , G01N2021/6478 , G01N2201/02 , G01N2201/062 , G01N2201/0626 , G01N2201/0627 , G01N2201/0636
摘要： Optical systems, and corresponding methods, for multiple reactions are provided. The optical systems are in a fixed position relative to a thermal assembly and include at least one array of excitation sources (e.g., light emitting diodes (LEDs)) configured to output excitation energy along an excitation optical path. In addition, a detector configured to receive emission energy along a detection optical path in the same plane as the excitation optical path is also provided.
摘要翻译：提供了多种反应的光学系统和相应的方法。光学系统相对于热组件处于固定位置，并且包括被配置为沿着激发光路输出激发能量的至少一组激励源（例如，发光二极管（LED））。此外，还提供了被配置为沿着与激励光路相同的平面中的检测光路接收发射能量的检测器。

98. 发明申请

US20110049386A1 FLUORESCENCE IMAGE PRODUCING METHOD, FLUORESCENCE IMAGE PRODUCING APPARATUS, AND FLUORESCENCE IMAGE PRODUCING PROGRAM 有权
标题翻译：荧光图像生产方法，荧光图像生产设备和荧光图像生产程序
公开(公告)号：US20110049386A1
公开(公告)日：2011-03-03
申请号：US12851748
申请日：2010-08-06
申请人： Koichiro Kishima , Takashi Yamamoto
发明人： Koichiro Kishima , Takashi Yamamoto
IPC分类号： G01J1/58 , G06K9/00
CPC分类号： A45D33/02 , G01J1/58 , G01N21/6458 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441 , G02B21/006 , G02B21/0076 , G02B21/10 , G02B21/16 , G02B21/244 , G02B21/367
摘要： Method and apparatus for producing an image associated with a biological sample is provided. The biological sample is focused on the biological sample based on fluorescence of a first fluorescent material and the image is captured based on fluorescence of the second fluorescent material. A computer readable memory device storing instructions to cause a data processing unit is also provided.
摘要翻译：提供了用于生产与生物样品相关联的图像的方法和装置。生物样品基于第一荧光材料的荧光聚焦在生物样品上，并且基于第二荧光材料的荧光捕获图像。还提供了存储用于引起数据处理单元的指令的计算机可读存储器件。

99. 发明申请

US20110012025A1 FLUORESCENCE OBSERVATION APPARATUS 审中-公开
标题翻译：荧光观察装置
公开(公告)号：US20110012025A1
公开(公告)日：2011-01-20
申请号：US12833337
申请日：2010-07-09
申请人： Shunji TAKEI
发明人： Shunji TAKEI
IPC分类号： G01J1/58
CPC分类号： A61B1/05 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/0684 , A61B5/0071 , A61B5/0084 , G01N2021/6441
摘要： A fluorescence observation apparatus according to the present invention includes a light source section that can emit a plurality of excitation light beams of different wavelength bands and select excitation light beams to be emitted to an object where there are a first fluorescent substance and a second fluorescent substance to be examined from among the plurality of excitation light beams, a variable filter section that selectively allows at least part of the wavelength band of returning light from the object to pass, a photo-detecting section that detects the light that has passed through the variable filter section, a calculation processing section that carries out calculations to determine a wavelength band of the excitation light emitted from the light source section and a transmission wavelength band in the variable filter section based on intensity characteristics of the plurality of excitation light beams, fluorescence characteristics of the first fluorescent substance and fluorescence characteristics of the second fluorescent substance and a control section that performs control of causing the light source section to interlock with the variable filter section based on the calculation result of the calculation processing section.
摘要翻译：根据本发明的荧光观察装置包括：光源部，其可以发射多个不同波长带的激发光束，并且选择要发射到具有第一荧光物质和第二荧光物质的物体的激发光束; 从所述多个激发光束中检查出可选滤波器部分，所述可变滤波器部分选择性地允许来自所述物体的返回光的波长带的至少一部分通过;光检测部分，其检测已经通过所述变量的光滤波器部分，计算处理部分，其基于多个激发光束的强度特性，执行计算以确定从光源部分发射的激发光的波长带和可变滤波器部分中的透射波长带，荧光特性的第一种荧光物质和流感基于计算处理部的计算结果，第二荧光体的荧光特性和控制部，其执行使光源部与可变滤波器部互锁的控制。

100. 发明申请

US20110005932A1 UNIVERSAL SAMPLE PREPARATION SYSTEM AND USE IN AN INTEGRATED ANALYSIS SYSTEM 有权
标题翻译：通用样品制备系统及其在综合分析系统中的应用
公开(公告)号：US20110005932A1
公开(公告)日：2011-01-13
申请号：US12795515
申请日：2010-06-07
申请人： Stevan B. JOVANOVICH , William D. Nielsen , David S. Cohen , Michael Recknor , Mattias Vangbo , Ezra Van Gelder , Lars Majlof , Omar El-Sissi
发明人： Stevan B. JOVANOVICH , William D. Nielsen , David S. Cohen , Michael Recknor , Mattias Vangbo , Ezra Van Gelder , Lars Majlof , Omar El-Sissi
IPC分类号： G01N27/447 , H01J5/16 , G01J1/58 , G01N21/64
CPC分类号： C12Q1/6806 , G01J3/4406 , G01N1/31 , G01N1/405 , G01N21/64 , G01N27/44721 , G01N27/44791 , G01N27/745 , G01N35/00029 , G01N2035/00148 , G01N2035/00247 , G01N2201/06113 , G01N2201/062 , Y10T436/11 , Y10T436/143333 , Y10T436/25 , Y10T436/2575
摘要： The invention provides a system that can process a raw biological sample, perform a biochemical reaction and provide an analysis readout. For example, the system can extract DNA from a swab, amplify STR loci from the DNA, and analyze the amplified loci and STR markers in the sample. The system integrates these functions by using microfluidic components to connect what can be macrofluidic functions. In one embodiment the system includes a sample purification module, a reaction module, a post-reaction clean-up module, a capillary electrophoresis module and a computer. In certain embodiments, the system includes a disposable cartridge for performing analyte capture. The cartridge can comprise a fluidic manifold having macrofluidic chambers mated with microfluidic chips that route the liquids between chambers. The system fits within an enclosure of no more than 10 ft3. and can be a closed, portable, and/or a battery operated system. The system can be used to go from raw sample to analysis in less than 4 hours.
摘要翻译：本发明提供一种可以处理原始生物样品，进行生化反应并提供分析读数的系统。例如，该系统可以从拭子中提取DNA，从DNA扩增STR基因座，并分析样品中扩增的位点和STR标记。该系统通过使用微流体组件来集成这些功能，以连接什么是宏流动功能。在一个实施方案中，该系统包括样品纯化模块，反应模块，反应后净化模块，毛细管电泳模块和计算机。在某些实施例中，该系统包括用于执行分析物捕获的一次性盒。墨盒可以包括流体歧管，该流体歧管具有与微流体芯片配合的大流动腔室，所述微流体芯片在腔室之间引导液体。该系统适合不超过10英尺3的外壳。并且可以是封闭的，便携式的和/或电池供电的系统。该系统可用于在不到4小时内从原始样品进行分析。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式