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11. 发明申请

US20120250821A1 COMPUTED TOMOGRAPHY APPARATUS 有权
标题翻译：计算机摄影装置
公开(公告)号：US20120250821A1
公开(公告)日：2012-10-04
申请号：US13509840
申请日：2010-12-10
申请人： Thomas Koehler , Roland Proksa , Ewald Roessl
发明人： Thomas Koehler , Roland Proksa , Ewald Roessl
IPC分类号： G01N23/04
CPC分类号： A61B6/032 , A61B6/469 , A61B6/542 , G01N23/046 , G01N2223/419 , G06T11/005 , Y10S378/901
摘要： The invention relates to a computed tomography apparatus for imaging an object. The computed tomography apparatus comprises a radiation source (2) for generating modulated radiation (4) traversing the object and a detector (6) for generating detection values depending on the radiation (4) after having traversed the object, while the radiation source (2) and the object are moved relative to each other. A weight providing unit (14) provides modulation weights for weighting the detection values depending on the modulation of the radiation (4) and a reconstruction unit (15) reconstructs an image of the object, wherein the detection values are weighted based on the provided modulation weights and an image of the object is reconstructed from the weighted detection values. This can allow to optimize the dose application to the object by modulating the radiation accordingly, wherein the reconstructed images still have a high quality.
摘要翻译：本发明涉及一种用于对物体成像的计算机断层摄影装置。计算机断层摄影装置包括用于产生经过物体的调制辐射（4）的辐射源（2）和用于在穿过物体之后产生取决于辐射（4）的检测值的检测器（6），而辐射源）并且对象相对于彼此移动。权重提供单元（14）根据辐射（4）的调制提供用于对检测值进行加权的调制权重，并且重建单元（15）重建对象的图像，其中基于所提供的调制对所述检测值进行加权从加权检测值重建对象的权重和图像。这可以通过相应地调节辐射来优化对物体的剂量应用，其中重建的图像仍然具有高质量。

12. 发明申请

US20120237097A1 MOTION COMPENSATION WITH TISSUE DENSITY RETENTION 有权
标题翻译：运动补偿与组织密度保持
公开(公告)号：US20120237097A1
公开(公告)日：2012-09-20
申请号：US13510153
申请日：2010-11-18
申请人： Thomas Koehler , Tobias Klinder , Sven Kabus
发明人： Thomas Koehler , Tobias Klinder , Sven Kabus
IPC分类号： G06K9/00
CPC分类号： G06T11/008 , G06T2211/412
摘要： A method includes reconstructing the projection data based on a reconstruction algorithm that compensates for both motion and tissue density changes of the moving organ across different motion phases, thereby generating motion and density compensated image data. A data compensator includes a reconstructor that reconstructs motion compensated image data based on an reconstruction algorithm that compensates for tissue density changes in a moving object.
摘要翻译：一种方法包括基于补偿运动器官在不同运动相位上的运动和组织密度变化的重建算法重建投影数据，从而产生运动和密度补偿图像数据。数据补偿器包括重建器，其基于补偿移动物体中的组织密度变化的重建算法重建运动补偿图像数据。

13. 发明申请

US20120165376A1 STABILIZED MICROBICIDAL COMPOSITION 审中-公开
标题翻译：稳定的微生物组合物
公开(公告)号：US20120165376A1
公开(公告)日：2012-06-28
申请号：US13323948
申请日：2011-12-13
申请人： Thomas Koehler , Pierre Marie Lenoir
发明人： Thomas Koehler , Pierre Marie Lenoir
IPC分类号： A01N37/34 , A01N43/80 , A01P1/00
CPC分类号： A01N37/34 , A01N43/80 , A01N2300/00 , A01N25/02 , A01N25/22 , A01N35/08
摘要： A microbicidal composition having at least four components. The first component is 2-25 wt % of 2,2-dibromo-3-nitrilopropionamide. The second component is 2-30 wt % water. The third component is 5-30 wt % of an aliphatic compound having 2-6 hydroxyl groups. The fourth component is 20-70 wt % of a glycol solvent.
摘要翻译：具有至少四种组分的杀微生物组合物。第一组分为2,2-二溴-3-次氮基丙酰胺的2-25重量％。第二组分为2-30重量％的水。第三成分为5-30重量％的具有2-6个羟基的脂肪族化合物。第四组分是二醇溶剂的20-70重量％。

14. 发明申请

US20120020461A1 ACHROMATIC PHASE-CONTRAST IMAGING 有权
标题翻译：高级相对成像
公开(公告)号：US20120020461A1
公开(公告)日：2012-01-26
申请号：US13260424
申请日：2010-03-19
申请人： Ewald Roessl , Thomas Koehler
发明人： Ewald Roessl , Thomas Koehler
IPC分类号： G01N23/20
CPC分类号： G21K1/06 , G02B27/52 , G21K2207/005
摘要： An achromatic phase-contrast imaging apparatus for examining an object of interest is provided which comprises two different phase gratings which have different pitches. Thus, the imaging apparatus yields phase-contrast information for two different energies. Thus, phase-information over a wider energy band can be used.
摘要翻译：提供一种用于检查感兴趣对象的消色差相位对比成像装置，其包括具有不同间距的两个不同的相位光栅。因此，成像装置产生两个不同能量的相位对比度信息。因此，可以使用较宽能带上的相位信息。

15. 发明申请

US20110142250A1 GRADIENT COIL NOISE MASKING FOR MPI DEVICE 审中-公开
标题翻译：用于MPI设备的梯度线圈噪声掩蔽
公开(公告)号：US20110142250A1
公开(公告)日：2011-06-16
申请号：US13058230
申请日：2009-08-11
申请人： Ingo Schmale , Thomas Koehler
发明人： Ingo Schmale , Thomas Koehler
IPC分类号： H04R3/02
CPC分类号： G10K11/175 , G01R33/288 , G01R33/3854 , H04K3/42 , H04K3/45 , H04K3/825 , H04K2203/12
摘要： When subjecting a patient to an MRI scan, noise generated by gradient coils in an MRI device is beautified by playing a complementary musical piece that matches the gradient coil noise in one or both of tempo and musical key. Complementary musical pieces (e.g., songs, tunes, melodies, etc.) are pre-generated for specific gradient coil sequences. Upon selection of one or more sequences to be executed during an MR scan, complementary musical pieces for the selected sequence(s) are identified and played back to a patient in the bore of the MRI device during the scan to alleviate patient stress. Tempo and/or musical key of the complementary musical pieces is adjustable (a priori or in real time) to synchronize the complementary musical piece(s) to a specific gradient sequence both rhythmically and harmonically.
摘要翻译：当患者进行MRI扫描时，通过在节奏和音乐键中的一个或两个中播放与梯度线圈噪声相匹配的互补乐曲来美化MRI设备中的梯度线圈产生的噪声。为特定的梯度线圈序列预先生成补充音乐作品（例如，歌曲，曲调，旋律等）。在选择在MR扫描期间要执行的一个或多个序列时，在扫描期间识别所选序列的补充音乐片段并将其回放到MRI装置的孔中的患者以减轻患者压力。互补音乐作品的速度和/或音乐键可以调整（先验或实时），以便将互补乐曲节奏地和谐音地同步到特定的梯度序列。

16. 发明申请

US20100272230A1 DETECTION SETUP FOR X-RAY PHASE CONTRAST IMAGING 有权
标题翻译：用于X射线相位对比成像的检测设置
公开(公告)号：US20100272230A1
公开(公告)日：2010-10-28
申请号：US12744070
申请日：2008-11-19
申请人： Thomas Koehler
发明人： Thomas Koehler
IPC分类号： G01N23/02
CPC分类号： A61B6/00 , A61B6/032 , A61B6/06 , A61B6/4291 , A61B6/484
摘要： The invention relates to a method and a device for generating phase contrast X-ray images of an object (1). The device comprises an X-ray source (10) that may for example be realized by a spatially extended emitter (11) behind a grating (G0). A diffractive optical element (DOE), for example a phase grating (G1), generates an interference pattern (I) from the X-radiation that has passed the object (1), and a spectrally resolving X-ray detector (30) is used to measure this interference pattern behind the DOE. Using the information obtained for different wavelengths/energies of X-radiation, the phase shift induced by the object can be reconstructed.
摘要翻译：本发明涉及一种用于产生对象（1）的相差X射线图像的方法和装置。该装置包括例如可以由光栅（G0）后面的空间扩展的发射器（11）实现的X射线源（10）。衍射光学元件（DOE），例如相位光栅（G1），从已经通过物体（1）的X射线产生干涉图案（I），光谱分辨X射线检测器（30）是用于测量DOE背后的干扰模式。使用对于X射线的不同波长/能量获得的信息，可以重建由对象引起的相移。

17. 发明授权

US07822171B2 Cone beam computed tomography with multiple partial scanning trajectories 失效
标题翻译：具有多个部分扫描轨迹的锥束计算机断层扫描
公开(公告)号：US07822171B2
公开(公告)日：2010-10-26
申请号：US12296945
申请日：2006-04-19
申请人： Claas Bontus , Thomas Koehler , Peter Koken , Andy Ziegler
发明人： Claas Bontus , Thomas Koehler , Peter Koken , Andy Ziegler
IPC分类号： A61B6/00
CPC分类号： G06T11/006 , A61B6/027 , G06T11/005
摘要： A computer tomography apparatus (100) for examination of an object of interest (107) comprising an electromagnetic radiation source (104) adapted to emit electromagnetic radiation to an object of interest (107), a detecting device (108) adapted to detect electromagnetic radiation generated by the electromagnetic radiation source (104) and passed through the object of interest (107), and a motion generation device (101, 119) adapted to move the electromagnetic radiation source (104) and the detecting device (108) with respect to the object of interest (107) along a first trajectory and along a second trajectory which differs from the first trajectory, wherein the second trajectory is selected in such a manner that electromagnetic radiation detected during performing the second trajectory provides data which complete mathematically incomplete data detected during performing the first trajectory to thereby allow a reconstruction of structural information concerning the object of interest (107).
摘要翻译：一种用于检查感兴趣对象（107）的计算机断层摄影装置（100），包括适于向感兴趣对象（107）发射电磁辐射的电磁辐射源（104），适于检测电磁辐射的检测装置由电磁辐射源（104）产生并通过感兴趣物体（107）的运动产生装置（101,119），适于相对于电磁辐射源（104）和检测装置（108）移动感兴趣的物体（107）沿着第一轨迹并且沿着与第一轨迹不同的第二轨迹，其中以这样的方式选择第二轨迹，使得在执行第二轨迹期间检测到的电磁辐射提供了完全数学上不完整的数据检测的数据在执行第一轨迹期间，从而允许重建关于感兴趣对象的结构信息（107）。

18. 发明授权

US07782997B2 Reconstruction algorithm for object point outside the scan-field-of-view 有权
标题翻译：对象点的重建算法在扫描视野外
公开(公告)号：US07782997B2
公开(公告)日：2010-08-24
申请号：US11994700
申请日：2006-07-04
申请人： Thomas Koehler , Peter Forthmann
发明人： Thomas Koehler , Peter Forthmann
IPC分类号： A61B6/00
CPC分类号： G06T11/006 , A61B6/027 , G06T2211/432
摘要： CT scanners have a certain scan-field-of-view defined by the fan-angle of the system. According to an exemplary embodiment of the present invention, object points outside the scan-field-of-view may be reconstructed on the basis of a system of linear equations which may be solved iteratively and with reasonable effort. Therefore, explicit regularization techniques may be applied to recover the unknown object function.
摘要翻译： CT扫描仪具有由系统的扇角定义的特定扫描视场。根据本发明的示例性实施例，可以基于可以以合理的努力迭代地解决的线性方程式的系统来重构扫描视场外的物点。因此，可以应用明确的正则化技术来恢复未知对象的功能。

19. 发明授权

US07702063B2 CT method for the examination of cyclically moving object 有权
标题翻译： CT方法检查循环移动物体
公开(公告)号：US07702063B2
公开(公告)日：2010-04-20
申请号：US11719305
申请日：2005-11-07
申请人： Thomas Koehler , Michael Grass
发明人： Thomas Koehler , Michael Grass
IPC分类号： A61B6/00
CPC分类号： A61B6/541 , A61B6/032 , A61B6/4085
摘要： The invention relates to a computer tomography method for the detection of a cyclically moved object in an examination zone. First, after the acquisition of the measured values, a rough image of the examination zone is reconstructed from which a region relevant for the further method is selected. For the generation of an image with reduced motion artifacts or improved temporal resolution, reconstruction windows in predefinable position are used, which are optimized in such a way that they are, on the one hand, smallest possible, on the other hand, however, sufficiently large, to be able to reconstruct all voxels of this region. Only measured values acquired within the reconstruction windows are taken into account for the reconstruction of a CT image of the region.
摘要翻译：本发明涉及一种用于在检查区域中检测循环移动物体的计算机断层摄影方法。首先，在获取测量值之后，重建检查区域的粗略图像，从中选择与该另一方法相关的区域。为了产生具有减少的运动伪影或改进的时间分辨率的图像，使用可预定义位置的重建窗口，其以这样的方式被优化：一方面，尽管如此，另一方面，足够的大，能够重建这个地区的所有体素。仅在重建窗口中获取的测量值被考虑用于重建该区域的CT图像。

20. 发明授权

US07623616B2 Computer tomography apparatus and method for examining an object of interest 失效
标题翻译：用于检查感兴趣对象的计算机断层摄影装置和方法
公开(公告)号：US07623616B2
公开(公告)日：2009-11-24
申请号：US11718724
申请日：2005-11-02
申请人： Andy Ziegler , Thomas Koehler , Michael Grass
发明人： Andy Ziegler , Thomas Koehler , Michael Grass
IPC分类号： G01N23/087 , G01N23/201
CPC分类号： G01T1/2985 , A61B6/027 , A61B6/032 , A61B6/4241 , A61B6/482 , A61B6/483 , G01V5/0025 , G01V5/005 , G06T11/006 , G06T2211/424
摘要： A computer tomography apparatus (100) for examination of an object of interest (107), the computer tomography apparatus (100) comprising detecting elements (123) adapted to detect electromagnetic radiation coherently scattered from an object of interest (107) in an energy-resolving manner, and a determination unit (118) adapted to determine structural information concerning the object of interest (107) based on a statistical analysis of detecting signals received from the detecting elements (123).
摘要翻译：一种用于检查感兴趣对象（107）的计算机断层摄影装置（100），所述计算机断层摄影装置（100）包括检测元件（123），所述检测元件适于检测能量相关物体（107）相干散射的电磁辐射，以及确定单元（118），其适于基于从所述检测元件（123）接收的检测信号的统计分析来确定关于感兴趣对象的结构信息（107）。

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