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11. 发明授权

US10098950B2 PD-1 Peptide Inhibitors 有权
公开(公告)号：US10098950B2
公开(公告)日：2018-10-16
申请号：US15705333
申请日：2017-09-15
申请人： Leidos, Inc.
发明人： Gabriel M. Gutierrez , Vinayaka Kotraiah , James Pannucci , Ramses Ayala
IPC分类号： A61K6/00 , A61K39/00 , A61K39/002 , A61K39/015 , A61K39/395 , A61K45/00 , A61K45/06 , C07K1/00 , C07K16/00 , C07K16/18 , C07K16/20 , A61K39/39 , A61K38/16 , A61K38/10 , C07K7/08
摘要： This disclosure provides peptides which have a strong affinity for the checkpoint receptor “programmed death 1” (PD-1). These peptides block the interaction of PD-1 with its ligand PD-L1 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer, treating infectious diseases, enhancing a response to vaccination, and treating sepsis.

12. 发明申请

US20180217291A1 Method For Autonomous Self-Blanking by Radiation Portal Monitors to Minimize the Interference From Pulsed X-Rays Radiation 审中-公开
公开(公告)号：US20180217291A1
公开(公告)日：2018-08-02
申请号：US15882070
申请日：2018-01-29
申请人： Leidos, Inc.
发明人： Adrian Stoian , Gregory Alan Greenwood
IPC分类号： G01V5/00
CPC分类号： G01V5/0016 , G01T1/17 , G01V5/0008 , G01V5/0066
摘要： A system and associated method for isolating intended radiation signals for determining target characteristics includes multiple detectors for detecting radiation signals having varying energies, delay modules for delaying the detected radiation signals and a discriminator associated with the multiple detectors for determining if detected radiation signals include unintended radiation signals, e.g., x-rays, and provided blanking signals to a switch in order to effectively remove the unintended radiation signals from the data that is presented to the processor for determining target characteristics.

13. 发明授权

US09978418B2 System and method for automated hardware compatibility testing 有权
公开(公告)号：US09978418B2
公开(公告)日：2018-05-22
申请号：US14886845
申请日：2015-10-19
申请人： Leidos, Inc.
发明人： Timothy William Estell , Bruce Allen Clark , Littleton Kent Riggins , Jeffrey Errol Cade , Ronald Franklin Cox , Martin William Sutton, Jr.
IPC分类号： G06F11/00 , G11B20/18 , G06F11/07 , G06F11/22
CPC分类号： G11B20/1816 , G06F11/0727 , G06F11/221
摘要： Systems and methods for automating testing of multiple SATA hard drives with multiple motherboards are described herein. In certain embodiments any number of SATA drives may be switchably connected to any number of motherboards, and any number of tests may be performed on combinations of the SATA drives and motherboards without or with only minimal manual intervention between tests. In one embodiment, the system may include an automated selector having a controller adapted to receive a testing instruction and transmit the received testing instruction and a mainboard in communication with the controller. The mainboard may include a logic device to receive the testing instruction from the controller and/or a switch for pairing and unpairing motherboards with SATA storage devices.

14. 发明申请

US20180132139A1 Method and System For Multiple Carrier Resource Allocation in LTE-Advanced Networks 审中-公开
公开(公告)号：US20180132139A1
公开(公告)日：2018-05-10
申请号：US15854113
申请日：2017-12-26
申请人： Leidos, Inc.
发明人： Rebecca K. Harrington
IPC分类号： H04W28/24 , H04W4/00 , H04M15/00 , H04W4/24
CPC分类号： H04W28/24 , H04M15/8044 , H04M15/805 , H04M15/8055 , H04W4/00 , H04W4/24
摘要： A process for selecting an optimal individual user solution including an optimal rate allocation and associated price for a predetermined bandwidth of cellular network resources includes application of an iterative process and selection from multiple proposed user solutions. The inputs to the iterative process include at least an initial user bid, an initial network rate allocation, a generated user utility function and the cost data. The user utility function includes multiple application user functions. Optimal solution selection includes comparing each multiple proposed user rate allocation with the initial network rate allocation for the user and selecting the closest multiple proposed user rate allocation to the initial network rate allocation. The process may be applied to aggregated cellular carrier scenarios.

15. 发明申请

US20180019629A1 Radial Flux Alternator 审中-公开
公开(公告)号：US20180019629A1
公开(公告)日：2018-01-18
申请号：US15708595
申请日：2017-09-19
申请人： Leidos, Inc.
发明人： Charles R. Fralick , Christopher J. Eckert
IPC分类号： H02K1/27 , H02K1/14 , H02K3/32 , H02K3/28 , H02K3/12
CPC分类号： H02K1/274 , H02K1/14 , H02K1/278 , H02K3/12 , H02K3/28 , H02K3/325 , Y02E10/725
摘要： An energy conversion system includes rotor, stator and shell components configurations for increasing power efficiency and improving replacement and repair efficiency. The system harvests environmental energy for lower power generation and accounts for non-mechanical sources of rotational resistance within the generator.

16. 发明授权

US09784192B2 System and method for managing a volatile organic compound emission stream 有权
公开(公告)号：US09784192B2
公开(公告)日：2017-10-10
申请号：US15352674
申请日：2016-11-16
申请人： Leidos, Inc.
发明人： William Ronald Steen , Scott Francis Coon
IPC分类号： B60L1/02 , F01K15/00 , F01K17/02 , F02C6/00 , F02C6/18 , F02D19/02 , F02M25/00 , H02K7/18 , F02D29/06 , F02D41/00 , B01D53/72 , F02G5/00 , F02B63/04 , F02C7/22 , F02C7/26 , F02D19/06
CPC分类号： F02D19/029 , B01D53/72 , B01D2257/708 , F02B63/04 , F02D19/0634 , F02D19/0642 , F02D29/06 , F02D41/0025 , F02D41/0027 , F02G5/00 , F02M25/00 , H02K7/1807 , H02K7/1815 , Y02E20/14 , Y02T10/16 , Y02T10/36
摘要： A Volatile Organic Compound (VOC) mitigation system employs a combination of technologies coupling VOC laden exhaust with a reciprocating engine and generator system (Combined Heat & Power (CHP) System) with heat recovery to destroy the VOC emissions and generate electric power and useful thermal energy.

17. 发明授权

US09528491B2 System and method for generated power from wave action 有权
标题翻译：波动作用产生电力的系统和方法
公开(公告)号：US09528491B2
公开(公告)日：2016-12-27
申请号：US14506016
申请日：2014-10-03
申请人： Leidos, Inc.
发明人： Steven C. Hench , Charles R. Fralick
IPC分类号： F03B13/20 , E02B9/08 , F15B11/08
CPC分类号： F03B13/20 , E02B9/08 , F05B2240/93 , F05B2260/406 , F15B11/08 , F15B2211/2053 , F15B2211/7058 , Y02E10/38
摘要： Wave energy conversion systems are provided utilizing a mass of water entrained in a collapsible water mass enclosure that is suspended beneath a float (e.g., a vehicle, buoy, platform, etc.) to provide an inertial force in opposition to the rising heave-induced acceleration of the float. The water mass enclosure is communication with a generator, such as by tethering one end of a tethering means to the generator and the other to the enclosure. The enclosure may be placed in communication with an intermediary hydraulic system, which is also in communication with the generator. In certain embodiments, the system will include a reel system for deploying and retrieving the water masse enclosure.
摘要翻译：提供了波浪能量转换系统，其利用悬挂在浮动体（例如，车辆，浮标，平台等）下方的可折叠水体箱体中的大量水，以提供与上升起伏引起的相反的惯性力加速浮子。水体外壳与发生器连通，例如通过将束缚装置的一端束缚到发生器，将另一端连接到外壳。外壳可以放置成与中间液压系统连通，中间液压系统也与发电机连通。在某些实施例中，该系统将包括一个用于展开和取回水闸外壳的卷轴系统。

18. 发明授权

US09501535B2 System and method for correlating cloud-based big data in real-time for intelligent analytics and multiple end uses 有权
公开(公告)号：US09501535B2
公开(公告)日：2016-11-22
申请号：US14809393
申请日：2015-07-27
申请人： Leidos, Inc.
发明人： Thomas James Cannaliato , Joshua A. Decker , Matthew William Vahlberg
IPC分类号： G06F17/30
CPC分类号： G06F17/30569 , G06F17/30294 , G06F17/30303 , G06F17/30377 , G06F17/30424 , G06F17/3048 , G06F17/30539 , G06F17/30592 , G06F17/30595 , G06F19/00 , G06F21/6254 , G16H10/60
摘要： A processing platform integrates ETL (extract, transform, and load), real time stream processing, and “big data” data stores into a high performance analytic system that runs in a public or private cloud. The platform performs real time pre-storage enrichment of data records to form a single comprehensive record usable for analytics, searching and alerting. The platform further supports sharing of components and plug-ins and performs automatic scaling of resources based on real time resource monitoring and analysis.

19. 发明申请

US20160337834A1 Method and System For Multiple Carrier Resource Allocation in LTE-Advanced Networks 有权
标题翻译： LTE-Advanced网络中多载波资源分配的方法与系统
公开(公告)号：US20160337834A1
公开(公告)日：2016-11-17
申请号：US15210142
申请日：2016-07-14
申请人： Leidos, Inc.
发明人： Rebecca K. Harrington
IPC分类号： H04W4/26 , H04W28/24
CPC分类号： H04W28/24 , H04M15/8044 , H04M15/805 , H04M15/8055 , H04W4/00 , H04W4/24
摘要： A process for selecting an optimal individual user solution including an optimal rate allocation and associated price for a predetermined bandwidth of cellular network resources includes application of an iterative process and selection from multiple proposed user solutions. The inputs to the iterative process include at least an initial user bid, an initial network rate allocation, a generated user utility function and the cost data. The user utility function includes multiple application user functions. Optimal solution selection includes comparing each multiple proposed user rate allocation with the initial network rate allocation for the user and selecting the closest multiple proposed user rate allocation to the initial network rate allocation. The process may be applied to aggregated cellular carrier scenarios.
摘要翻译：用于选择包括蜂窝网络资源的预定带宽的最优速率分配和相关价格的最佳个体用户解决方案的过程包括迭代过程的应用和来自多个提出的用户解决方案的选择。迭代过程的输入至少包括初始用户出价，初始网络速率分配，生成的用户效用函数和成本数据。用户效用函数包括多个应用程序用户功能。最佳解决方案选择包括将每个多个提出的用户速率分配与用户的初始网络速率分配进行比较，并且选择与最初的网络速率分配最接近的多个提出的用户速率分配。该过程可以应用于聚合的蜂窝载波场景。

20. 发明申请

US20160299102A1 System and Method For Fusing Chemical Detectors 审中-公开
标题翻译：用于熔化化学检测器的系统和方法
公开(公告)号：US20160299102A1
公开(公告)日：2016-10-13
申请号：US15190338
申请日：2016-06-23
申请人： Leidos, Inc.
发明人： Charles Stephen Harden , Robert James Schafer
IPC分类号： G01N27/62
CPC分类号： H01J49/0095 , G01N27/622 , G01N27/624 , H01J49/0013 , H01J49/0022 , H01J49/004 , H01J49/009
摘要： Two complementary approaches to the science of IMS technology, IMS and differential IMS (DIMS), are combined into a single instrument to provide improvements in interference rejection without sacrificing detection sensitivity. The technology is applicable to, inter alia, the analysis of trace quantities of toxic or otherwise dangerous organic chemical materials. The approach improves both sensitivity and specificity (interference rejection) of field detection instrumentation.
摘要翻译：将IMS技术，IMS和差分IMS（DIMS）的科学技术的两种互补方法组合成一个单一的仪器，以提供干扰抑制的改进，而不会牺牲检测灵敏度。该技术特别适用于痕量有毒或其他危险的有机化学材料的分析。该方法提高了现场检测仪器的灵敏度和特异性（干扰抑制）。

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